Generation and characterization of a CYP2A13/2B6/2F1-transgenic mouse model

Drug Metabolism and Disposition

Volumn 40, Issue 6, 2012, Pages 1144-1150

  Wei, Yuan ^a,b   Wu, Hong ^a,b   Li, Lei ^a,b   Liu, Zhihua ^a,b   Zhou, Xin ^a,b   Zhang, Qing Yu ^a,b   Weng, Yan ^a,b   D'Agostino, Jaime ^a,b   Ling, Guoyu ^a,b   Zhang, Xiuling ^a,b   Kluetzman, Kerri ^a,b   Yao, Yunyi ^a,b   Ding, Xinxin ^a,b  

^a WADSWORTH CENTER   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; CYTOCHROME P450; CYTOCHROME P450 2A; CYTOCHROME P450 2A13; CYTOCHROME P450 2B6; CYTOCHROME P450 2F1; GENOMIC DNA; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOCHROME P450 2A13 GENE; CYTOCHROME P450 2B6 GENE; CYTOCHROME P450 2F1 GENE; DEVELOPMENT; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME SUBSTRATE; FEMALE; FERTILITY; GENE EXPRESSION REGULATION; GENE FUNCTION; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; LIMIT OF DETECTION; LIVER; LUNG PARENCHYMA; MALE; MORPHOLOGICAL TRAIT; MOUSE; NONHUMAN; NOSE MUCOSA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TISSUE DISTRIBUTION; TRANSGENE; TRANSGENIC MOUSE; WILD TYPE;

ADOLESCENT; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HUMANS; LIVER; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, ANIMAL; MULTIGENE FAMILY; NASAL MUCOSA; OXIDOREDUCTASES, N-DEMETHYLATING; TISSUE DISTRIBUTION;

MUS; MUS MUSCULUS;

EID: 84862110339     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.112.044826     Document Type: Article

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