메뉴 건너뛰기




Volumn 311, Issue 1, 2004, Pages 373-381

Development of a real-time polymerase chain reaction-based method for the measurement of relative allelic expression and identification of CYP2A13 alleles with decreased expression in human lung

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2A; CYTOCHROME P450 2A13; DNA; MESSENGER RNA; NITROSAMINE; UNCLASSIFIED DRUG;

EID: 4644227631     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.069872     Document Type: Article
Times cited : (25)

References (37)
  • 1
    • 0042856457 scopus 로고    scopus 로고
    • Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: Characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1
    • Aklillu E, Carrillo JA, Makonnen E, Hellman K, Pitarque M, Bertilsson L, and Ingelman-Sundberg M (2003) Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1. Mol Pharmacol 64:659-669.
    • (2003) Mol Pharmacol , vol.64 , pp. 659-669
    • Aklillu, E.1    Carrillo, J.A.2    Makonnen, E.3    Hellman, K.4    Pitarque, M.5    Bertilsson, L.6    Ingelman-Sundberg, M.7
  • 4
    • 0031958575 scopus 로고    scopus 로고
    • Rapid, efficient method for multiplex amplification from filter paper
    • Caggana M, Conroy JM, and Pass KA (1998) Rapid, efficient method for multiplex amplification from filter paper. Hum Mutat 11:404-409.
    • (1998) Hum Mutat , vol.11 , pp. 404-409
    • Caggana, M.1    Conroy, J.M.2    Pass, K.A.3
  • 6
    • 0141628887 scopus 로고    scopus 로고
    • Immunoblot analysis and immunohistochemical characterization of CYP2A expression in human olfactory mucosa
    • Chen Y, Liu YQ, Su T, Ren X, Shi L, Liu DZ, Gu J, Zhang Q-Y, and Ding X (2003) Immunoblot analysis and immunohistochemical characterization of CYP2A expression in human olfactory mucosa. Biochem Pharmacol 66:1245-1251.
    • (2003) Biochem Pharmacol , vol.66 , pp. 1245-1251
    • Chen, Y.1    Liu, Y.Q.2    Su, T.3    Ren, X.4    Shi, L.5    Liu, D.Z.6    Gu, J.7    Zhang, Q.-Y.8    Ding, X.9
  • 12
    • 0035434678 scopus 로고    scopus 로고
    • A cluster of three single nucleotide polymorphisms in the 3′-untranslated region of human glycoprotein PC-1 gene stabilizes PC-1 mRNA and is associated with increased PC-1 protein content and insulin resistance-related abnormalities
    • Frittitta L, Ercolino T, Bozzali M, Argiolas A, Graci S, Santagati MG, Spampinato D, Di Paola R, Cisternino C, Tassi V, et al. (2001) A cluster of three single nucleotide polymorphisms in the 3′-untranslated region of human glycoprotein PC-1 gene stabilizes PC-1 mRNA and is associated with increased PC-1 protein content and insulin resistance-related abnormalities. Diabetes 50:1952-1955.
    • (2001) Diabetes , vol.50 , pp. 1952-1955
    • Frittitta, L.1    Ercolino, T.2    Bozzali, M.3    Argiolas, A.4    Graci, S.5    Santagati, M.G.6    Spampinato, D.7    Di Paola, R.8    Cisternino, C.9    Tassi, V.10
  • 14
    • 0034212519 scopus 로고    scopus 로고
    • Expression of biotransformation enzymes in human fetal olfactory mucosa: Potential roles in developmental toxicity
    • Gu J, Su T, Chen Y, Zhang Q-Y, and Ding X (2000) Expression of biotransformation enzymes in human fetal olfactory mucosa: potential roles in developmental toxicity. Toxicol Appl Pharmacol 165:158-162.
    • (2000) Toxicol Appl Pharmacol , vol.165 , pp. 158-162
    • Gu, J.1    Su, T.2    Chen, Y.3    Zhang, Q.-Y.4    Ding, X.5
  • 15
    • 0035175053 scopus 로고    scopus 로고
    • Organization, structure and evolution of the CYP2 gene cluster on human chromosome 19
    • Hoffman SM, Nelson DR, and Keeney DS (2001) Organization, structure and evolution of the CYP2 gene cluster on human chromosome 19. Pharmacogenetics 11:687-698.
    • (2001) Pharmacogenetics , vol.11 , pp. 687-698
    • Hoffman, S.M.1    Nelson, D.R.2    Keeney, D.S.3
  • 16
    • 0037102094 scopus 로고    scopus 로고
    • mRNA-specific reverse transcription-polymerase chain reaction from human tissue extracts
    • Hurteau GJ and Spivack SD (2002) mRNA-specific reverse transcription-polymerase chain reaction from human tissue extracts. Anal Biochem 307:304-315.
    • (2002) Anal Biochem , vol.307 , pp. 304-315
    • Hurteau, G.J.1    Spivack, S.D.2
  • 17
    • 0032797302 scopus 로고    scopus 로고
    • A novel transversion in the intron 5 donor splice junction of CYP2C19 and a sequence polymorphism in exon 3 contribute to the poor metabolizer phenotype for the anticonvulsant drug S-mephenytoin
    • Ibeanu GC, Blaisdell J, Ferguson RJ, Ghanayem BI, Brosen K, Benhamou S, Bouchardy C, Wilkinson GR, Dayer P, and Goldstein JA (1999) A novel transversion in the intron 5 donor splice junction of CYP2C19 and a sequence polymorphism in exon 3 contribute to the poor metabolizer phenotype for the anticonvulsant drug S-mephenytoin. J Pharmacol Exp Ther 290:635-640.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 635-640
    • Ibeanu, G.C.1    Blaisdell, J.2    Ferguson, R.J.3    Ghanayem, B.I.4    Brosen, K.5    Benhamou, S.6    Bouchardy, C.7    Wilkinson, G.R.8    Dayer, P.9    Goldstein, J.A.10
  • 18
    • 0141792916 scopus 로고    scopus 로고
    • Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13
    • Jalas JR, Ding X, and Murphy SE (2003) Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13. Drug Metab Dispos 31:1199-1202.
    • (2003) Drug Metab Dispos , vol.31 , pp. 1199-1202
    • Jalas, J.R.1    Ding, X.2    Murphy, S.E.3
  • 23
    • 0037397619 scopus 로고    scopus 로고
    • Optimization of quantitative real-time RT-PCR parameters for the study of lymphoid malignancies
    • Lossos IS, Czerwinski DK, Wechser MA, and Levy R (2003) Optimization of quantitative real-time RT-PCR parameters for the study of lymphoid malignancies. Leukemia 17:789-795.
    • (2003) Leukemia , vol.17 , pp. 789-795
    • Lossos, I.S.1    Czerwinski, D.K.2    Wechser, M.A.3    Levy, R.4
  • 24
    • 0036135704 scopus 로고    scopus 로고
    • Quantification of single nucleotide polymorphisms: A novel method that combines primer extension assay and capillary electrophoresis
    • Matyas G, Giunta C, Steinmann B, Hossle JP, and Hellwig R (2002) Quantification of single nucleotide polymorphisms: a novel method that combines primer extension assay and capillary electrophoresis. Hum Mutat 19:58-68.
    • (2002) Hum Mutat , vol.19 , pp. 58-68
    • Matyas, G.1    Giunta, C.2    Steinmann, B.3    Hossle, J.P.4    Hellwig, R.5
  • 25
    • 0032929010 scopus 로고    scopus 로고
    • Genetic polymorphism in the 5′-flanking region of human CYP1A2 gene: Effect on the CYP1A2 inducibility in humans
    • Nakajima M, Yokoi T, Mizutani M, Kinoshita M, Funayama M, and Kamataki T (1999) Genetic polymorphism in the 5′-flanking region of human CYP1A2 gene: effect on the CYP1A2 inducibility in humans. J Biochem 125:803-808.
    • (1999) J Biochem , vol.125 , pp. 803-808
    • Nakajima, M.1    Yokoi, T.2    Mizutani, M.3    Kinoshita, M.4    Funayama, M.5    Kamataki, T.6
  • 26
    • 0032580320 scopus 로고    scopus 로고
    • Two-sided confidence intervals for the single proportion - Comparison of seven methods
    • Newcombe RG (1998) Two-sided confidence intervals for the single proportion - comparison of seven methods. Stat Med 17:857-872.
    • (1998) Stat Med , vol.17 , pp. 857-872
    • Newcombe, R.G.1
  • 27
    • 0034816629 scopus 로고    scopus 로고
    • Identification of a single nucleotide polymorphism in the TATA box of the CYP2A6 gene: Impairment of its promoter activity
    • Pitarque M, von Richter O, Oke B, Berkkan H, Oscarson M, and Ingelman-Sundberg M (2001) Identification of a single nucleotide polymorphism in the TATA box of the CYP2A6 gene: impairment of its promoter activity. Biochem Biophys Res Commun 284:455-460.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 455-460
    • Pitarque, M.1    Von Richter, O.2    Oke, B.3    Berkkan, H.4    Oscarson, M.5    Ingelman-Sundberg, M.6
  • 29
    • 0032908778 scopus 로고    scopus 로고
    • Functional significance of a C-> A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine
    • Sachse C, Brockmoller J, Bauer S, and Roots I (1999) Functional significance of a C-> A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine. Br J Clin Pharmacol 47:445-449.
    • (1999) Br J Clin Pharmacol , vol.47 , pp. 445-449
    • Sachse, C.1    Brockmoller, J.2    Bauer, S.3    Roots, I.4
  • 30
    • 0142119396 scopus 로고    scopus 로고
    • Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs)
    • Saito S, Iida A, Sekine A, Kawauchi S, Higuchi S, Ogawa C, and Nakamura Y (2003) Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs). J Hum Genet 48:461-468.
    • (2003) J Hum Genet , vol.48 , pp. 461-468
    • Saito, S.1    Iida, A.2    Sekine, A.3    Kawauchi, S.4    Higuchi, S.5    Ogawa, C.6    Nakamura, Y.7
  • 31
    • 0033651177 scopus 로고    scopus 로고
    • Characterization of human CYP2G genes: Widespread loss-of-function mutations and genetic polymorphism
    • Sheng JJ, Guo JC, Hua ZC, Caggana M, and Ding X (2000) Characterization of human CYP2G genes: widespread loss-of-function mutations and genetic polymorphism. Pharmacogenetics 10:667-678.
    • (2000) Pharmacogenetics , vol.10 , pp. 667-678
    • Sheng, J.J.1    Guo, J.C.2    Hua, Z.C.3    Caggana, M.4    Ding, X.5
  • 32
    • 0034665139 scopus 로고    scopus 로고
    • Human cytochrome P450 CYP2A13: Predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    • Su T, Bao Z, Zhang Q-Y, Smith TJ, Hong J-Y, and Ding X (2000) Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res 60:5074-5079.
    • (2000) Cancer Res , vol.60 , pp. 5074-5079
    • Su, T.1    Bao, Z.2    Zhang, Q.-Y.3    Smith, T.J.4    Hong, J.-Y.5    Ding, X.6
  • 33
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, and Speleman F (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3:1-12.
    • (2002) Genome Biol , vol.3 , pp. 1-12
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 34
    • 0345707570 scopus 로고    scopus 로고
    • Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK
    • Wang HJ, Tan W, Hao BT, Miao XP, Zhou GQ, He FH, and Lin DX (2003) Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK. Cancer Res 63:8057-8061.
    • (2003) Cancer Res , vol.63 , pp. 8057-8061
    • Wang, H.J.1    Tan, W.2    Hao, B.T.3    Miao, X.P.4    Zhou, G.Q.5    He, F.H.6    Lin, D.X.7
  • 37
    • 0036070530 scopus 로고    scopus 로고
    • Genetic polymorphisms of the human CYP2A13 gene: Identification of single-nucleotide polymorphisms and functional characterization of an Arg257Cys variant
    • Zhang XL, Su T, Zhang Q-Y, Gu J, Caggana M, Li H, and Ding X (2002) Genetic polymorphisms of the human CYP2A13 gene: identification of single-nucleotide polymorphisms and functional characterization of an Arg257Cys variant. J Pharmacol Exp Ther 302:416-423.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 416-423
    • Zhang, X.L.1    Su, T.2    Zhang, Q.-Y.3    Gu, J.4    Caggana, M.5    Li, H.6    Ding, X.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.