Generation and characterization of a Cyp2f2-null mouse and studies on the role of CYP2F2 in naphthalene-induced toxicity in the lung and nasal olfactory mucosa

Journal of Pharmacology and Experimental Therapeutics

Volumn 339, Issue 1, 2011, Pages 62-71

  Li, Lei ^a   Wei, Yuan ^a   Van Winkle, Laura ^b   Zhang, Qing Yu ^a   Zhou, Xin ^a   Hu, Jinping ^a   Xie, Fang ^a   Kluetzman, Kerri ^a   Ding, Xinxin ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 2F2; EPOXYGENASE; MICROSOME ENZYME; NAPHTHALENE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; CYP2F2 GENE; DRUG CLEARANCE; DRUG CYTOTOXICITY; EXON; GENE; GENE EXPRESSION; HOMOZYGOTE; IN VITRO STUDY; LIVER; LUNG; LUNG TOXICITY; MICROSOME; NONHUMAN; NOSE MUCOSA; PRIORITY JOURNAL;

ANIMALS; BIOTRANSFORMATION; BLOTTING, WESTERN; CYTOCHROME P-450 ENZYME SYSTEM; EMBRYONIC STEM CELLS; FEMALE; GLUTATHIONE; IMMUNOHISTOCHEMISTRY; LIVER; LUNG DISEASES; MICE; MICE, INBRED CBA; MICE, KNOCKOUT; MICROSOMES; NAPHTHALENES; NOSE DISEASES; OLFACTORY MUCOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SULFHYDRYL COMPOUNDS;

EID: 80053137032     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.184671     Document Type: Article

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