Beyond HLA-A*0201: New HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8 + T cell epitopes

Journal of Immunology

Volumn 188, Issue 11, 2012, Pages 5766-5775

  Antal, Zoltan ^a,b,g   Baker, Jason C ^a,g   Smith, Carla ^a   Jarchum, Irene ^a,h   Babad, Jeffrey ^a   Mukherjee, Gayatri ^a   Yang, Yang ^a,d   Sidney, John ^e   Sette, Alessandro ^e   Santamaria, Pere ^c,d,f   DiLorenzo, Teresa P ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL AT MONTEFIORE   (United States)

^c UNIVERSITY OF CALGARY   (Canada)

^d UNIVERSITY OF CALGARY   (Canada)

^e LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^f INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^g WEILL CORNELL MEDICAL COLLEGE   (United States)

^h MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; C PEPTIDE; HLA A ANTIGEN; HLA A3 ANTIGEN; HLA B ANTIGEN; HLA B7 ANTIGEN; EPITOPE; HLA A*02:01 ANTIGEN; HLA A11 ANTIGEN; HLA A2 ANTIGEN; HLA-A*02:01 ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; FEMALE; GENE; HLA A GENE; HLA B GENE; IMMUNE RESPONSE; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; TRANSGENICS; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMISTRY; GENETIC PREDISPOSITION; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; PROTEIN BINDING; TRANSGENIC MOUSE;

ANIMALS; C-PEPTIDE; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DIABETES MELLITUS, TYPE 1; EPITOPES, T-LYMPHOCYTE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HLA-A11 ANTIGEN; HLA-A2 ANTIGEN; HUMANS; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, TRANSGENIC; PROTEIN BINDING;

EID: 84862106232     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102930     Document Type: Article

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