Immunotargeting of insulin reactive CD8 T cells to prevent Diabetes

Journal of Autoimmunity

Volumn 35, Issue 4, 2010, Pages 390-397

  Scott, Gwen S ^a   Fishman, Sigal ^b   Khai Siew, L ^a   Margalit, Alon ^b,c   Chapman, Stephen ^a   Chervonsky, Alexander V ^d   Wen, Li ^e   Gross, Gideon ^b,c   Susan Wong, F ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b MIGAL GALILEE TECHNOLOGY CENTER   (Israel)

^c TEL HAI COLLEGE   (Israel)

^d UNIVERSITY OF CHICAGO   (United States)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytotoxic T cells; Cytotoxicity; Diabetes; Rodent

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; FAS ANTIGEN; FAS LIGAND; INSULIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE DERIVATIVE; PERFORIN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL KILLING; CELL MIGRATION; CONTROLLED STUDY; DIABETES MELLITUS; DIABETOGENESIS; DISEASE COURSE; IN VITRO STUDY; IN VIVO STUDY; INCIDENCE; INSULIN DEPENDENT DIABETES MELLITUS; LYMPH NODE; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; TARGET CELL; TRANSGENIC MOUSE;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD3; AUTOANTIGENS; CD8-POSITIVE T-LYMPHOCYTES; CYTOTOXICITY, IMMUNOLOGIC; DIABETES MELLITUS, TYPE 1; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; INSULIN; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; RECOMBINANT FUSION PROTEINS;

EID: 77958153192     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2010.08.005     Document Type: Article

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