-
1
-
-
33644749322
-
Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: Many differences, few similarities
-
Cnop M, Welsh N, Jonas JC, Jorns A, Lenzen S, Eizirik DL. Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 2005. 54(Suppl 2):S97-S107.
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL. 2
-
-
Cnop, M.1
Welsh, N.2
Jonas, J.C.3
Jorns, A.4
Lenzen, S.5
Eizirik, D.L.6
-
2
-
-
0035668779
-
A choice of death - the signal-transduction of immune-mediated beta-cell apoptosis
-
Eizirik DL, Mandrup-Poulsen T. A choice of death - the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia 2001. 44:2115-2133.
-
(2001)
Diabetologia
, vol.44
, pp. 2115-2133
-
-
Eizirik, D.L.1
Mandrup-Poulsen, T.2
-
3
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 2003. 52:102-110.
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
4
-
-
26444442450
-
Endoplasmic reticulum stress: Cell life and death decisions
-
Xu C, Bailly-Maitre B, Reed JC. Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 2005. 115:2656-2664.
-
(2005)
J Clin Invest
, vol.115
, pp. 2656-2664
-
-
Xu, C.1
Bailly-Maitre, B.2
Reed, J.C.3
-
5
-
-
0036895383
-
Endoplasmic reticulum stress and the development of diabetes: A review
-
Harding HP, Ron D. Endoplasmic reticulum stress and the development of diabetes: a review. Diabetes 2002. 51 (Suppl 3):S455-S461.
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL. 3
-
-
Harding, H.P.1
Ron, D.2
-
6
-
-
0036022403
-
Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells
-
Oyadomari S, Araki E, Mori M. Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells. Apoptosis 2002. 7:335-345.
-
(2002)
Apoptosis
, vol.7
, pp. 335-345
-
-
Oyadomari, S.1
Araki, E.2
Mori, M.3
-
7
-
-
33646166752
-
Endoplasmic reticulum stress-induced apoptosis and auto-immunity in diabetes
-
Lipson KL, Fonseca SG, Urano F. Endoplasmic reticulum stress-induced apoptosis and auto-immunity in diabetes. Curr Mol Med 2006. 6:71-77.
-
(2006)
Curr Mol Med
, vol.6
, pp. 71-77
-
-
Lipson, K.L.1
Fonseca, S.G.2
Urano, F.3
-
8
-
-
0035845568
-
Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway
-
Oyadomari S, Takeda K, Takiguchi M, Gotoh T, Matsumoto M, Wada I, Akira S, Araki E, Mori M. Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway. Proc Natl Acad Sci U S A 2001. 98:10845-10850.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10845-10850
-
-
Oyadomari, S.1
Takeda, K.2
Takiguchi, M.3
Gotoh, T.4
Matsumoto, M.5
Wada, I.6
Akira, S.7
Araki, E.8
Mori, M.9
-
9
-
-
4644233237
-
Response of human islets to isolation stress and the effect of antioxidant treatment
-
Bottino R, Balamurugan AN, Tse H, Thirunavukkarasu C, Ge X, Profozich J, Milton M, Ziegenfuss A, Trucco M, Piganelli JD. Response of human islets to isolation stress and the effect of antioxidant treatment. Diabetes 2004. 53:2559-2568.
-
(2004)
Diabetes
, vol.53
, pp. 2559-2568
-
-
Bottino, R.1
Balamurugan, A.N.2
Tse, H.3
Thirunavukkarasu, C.4
Ge, X.5
Profozich, J.6
Milton, M.7
Ziegenfuss, A.8
Trucco, M.9
Piganelli, J.D.10
-
10
-
-
0032918044
-
A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse
-
Wang J, Takeuchi T, Tanaka S, Kubo SK, Kayo T, Lu D, Takata K, Koizumi A, Izumi T. A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse. J Clin Invest 1999. 103:27-37.
-
(1999)
J Clin Invest
, vol.103
, pp. 27-37
-
-
Wang, J.1
Takeuchi, T.2
Tanaka, S.3
Kubo, S.K.4
Kayo, T.5
Lu, D.6
Takata, K.7
Koizumi, A.8
Izumi, T.9
-
11
-
-
0033048175
-
Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein
-
Arden SD, Zahn T, Steegers S, Webb S, Bergman B, O'Brien RM, Hutton JC. Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein. Diabetes 1999. 48:531-542.
-
(1999)
Diabetes
, vol.48
, pp. 531-542
-
-
Arden, S.D.1
Zahn, T.2
Steegers, S.3
Webb, S.4
Bergman, B.5
O'Brien, R.M.6
Hutton, J.C.7
-
12
-
-
0037478632
-
Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes
-
Lieberman SM, Evans AM, Han B, Takaki T, Vinnitskaya Y, Caldwell JA, Serreze DV, Shabanowitz J, Hunt DF, Nathenson SG, et al. Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes. Proc Natl Acad Sci U S A 2003. 100:8384-8388.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 8384-8388
-
-
Lieberman, S.M.1
Evans, A.M.2
Han, B.3
Takaki, T.4
Vinnitskaya, Y.5
Caldwell, J.A.6
Serreze, D.V.7
Shabanowitz, J.8
Hunt, D.F.9
Nathenson, S.G.10
-
13
-
-
0028931879
-
Beta-cell-cytotoxic CD8+ T cells from nonobese diabetic mice use highly homologous T cell receptor alpha-chain CDR3 sequences
-
Santamaria P, Utsugi T, Park BJ, Averill N, Kawazu S, Yoon JW. Beta-cell-cytotoxic CD8+ T cells from nonobese diabetic mice use highly homologous T cell receptor alpha-chain CDR3 sequences. J Immunol 1995. 154:2494-2503.
-
(1995)
J Immunol
, vol.154
, pp. 2494-2503
-
-
Santamaria, P.1
Utsugi, T.2
Park, B.J.3
Averill, N.4
Kawazu, S.5
Yoon, J.W.6
-
14
-
-
0030588572
-
Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains
-
Verdaguer J, Yoon JW, Anderson B, Averill N, Utsugi T, Park BJ, Santamaria P. Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains. J Immunol 1996. 157:4726-4735.
-
(1996)
J Immunol
, vol.157
, pp. 4726-4735
-
-
Verdaguer, J.1
Yoon, J.W.2
Anderson, B.3
Averill, N.4
Utsugi, T.5
Park, B.J.6
Santamaria, P.7
-
15
-
-
0030724897
-
Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice
-
Verdaguer J, Schmidt D, Amrani A, Anderson B, Averill N, Santamaria P. Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice. J Exp Med 1997. 186:1663-1676.
-
(1997)
J Exp Med
, vol.186
, pp. 1663-1676
-
-
Verdaguer, J.1
Schmidt, D.2
Amrani, A.3
Anderson, B.4
Averill, N.5
Santamaria, P.6
-
16
-
-
0032514701
-
Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement
-
DiLorenzo TP, Graser RT, Ono T, Christianson GJ, Chapman HD, Roopenian DC, Nathenson SG, Serreze DV. Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement. Proc Natl Acad Sci U S A 1998. 95:12538-12543.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 12538-12543
-
-
DiLorenzo, T.P.1
Graser, R.T.2
Ono, T.3
Christianson, G.J.4
Chapman, H.D.5
Roopenian, D.C.6
Nathenson, S.G.7
Serreze, D.V.8
-
17
-
-
0034680105
-
Progression of autoimmune diabetes driven by avidity maturation of a T-cell population
-
Amrani A, Verdaguer J, Serra P, Tafuro S, Tan R, Santamaria P. Progression of autoimmune diabetes driven by avidity maturation of a T-cell population. Nature 2000. 406:739-742.
-
(2000)
Nature
, vol.406
, pp. 739-742
-
-
Amrani, A.1
Verdaguer, J.2
Serra, P.3
Tafuro, S.4
Tan, R.5
Santamaria, P.6
-
18
-
-
34249107054
-
Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men
-
In press
-
Unger WW, Pinkse GG, Mulder-van der Kracht S, van der Slik AR, Kester M, Ossendorp F, Drijfhout JW, Serreze D, Roep BO. Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men. Ann N Y Acad Sci 2007. In press.
-
(2007)
Ann N Y Acad Sci
-
-
Unger, W.W.1
Pinkse, G.G.2
Mulder-van der Kracht, S.3
van der Slik, A.R.4
Kester, M.5
Ossendorp, F.6
Drijfhout, J.W.7
Serreze, D.8
Roep, B.O.9
-
19
-
-
33847338541
-
CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes
-
Mallone R, Martinuzzi E, Blancou P, Novelli G, Afonso G, Dolz M, Bruno G, Chaillous L, Chatenoud L, Bach JM, et al. CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes. Diabetes 2007. 56:613-621.
-
(2007)
Diabetes
, vol.56
, pp. 613-621
-
-
Mallone, R.1
Martinuzzi, E.2
Blancou, P.3
Novelli, G.4
Afonso, G.5
Dolz, M.6
Bruno, G.7
Chaillous, L.8
Chatenoud, L.9
Bach, J.M.10
-
20
-
-
33845539536
-
Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes
-
Ouyang Q, Standifer NE, Qin H, Gottlieb P, Verchere CB, Nepom GT, Tan R, Panagiotopoulos C. Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes. Diabetes 2006. 55:3068-3074.
-
(2006)
Diabetes
, vol.55
, pp. 3068-3074
-
-
Ouyang, Q.1
Standifer, N.E.2
Qin, H.3
Gottlieb, P.4
Verchere, C.B.5
Nepom, G.T.6
Tan, R.7
Panagiotopoulos, C.8
-
21
-
-
0034968330
-
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival
-
Harding HP, Zeng H, Zhang Y, Jungries R, Chung P, Plesken H, Sabatini DD, Ron D. Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival. Mol Cell 2001. 7:1153-1163.
-
(2001)
Mol Cell
, vol.7
, pp. 1153-1163
-
-
Harding, H.P.1
Zeng, H.2
Zhang, Y.3
Jungries, R.4
Chung, P.5
Plesken, H.6
Sabatini, D.D.7
Ron, D.8
-
22
-
-
1942475176
-
The role of endoplasmic reticulum stress in nonimmune diabetes: NOD.k iHEL, a novel model of beta cell death
-
Socha L, Silva D, Lesage S, Goodnow C, Petrovsky N. The role of endoplasmic reticulum stress in nonimmune diabetes: NOD.k iHEL, a novel model of beta cell death. Ann N Y Acad Sci 2003. 1005:178-183.
-
(2003)
Ann N Y Acad Sci
, vol.1005
, pp. 178-183
-
-
Socha, L.1
Silva, D.2
Lesage, S.3
Goodnow, C.4
Petrovsky, N.5
-
23
-
-
0036175128
-
Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes
-
Oyadomari S, Koizumi A, Takeda K, Gotoh T, Akira S, Araki E, Mori M. Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes. J Clin Invest 2002. 109:525-532.
-
(2002)
J Clin Invest
, vol.109
, pp. 525-532
-
-
Oyadomari, S.1
Koizumi, A.2
Takeda, K.3
Gotoh, T.4
Akira, S.5
Araki, E.6
Mori, M.7
-
24
-
-
0024281396
-
Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells
-
Lo D, Burkly LC, Widera G, Cowing C, Flavell RA, Palmiter RD, Brinster RL. Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells. Cell 1988. 53:159-168.
-
(1988)
Cell
, vol.53
, pp. 159-168
-
-
Lo, D.1
Burkly, L.C.2
Widera, G.3
Cowing, C.4
Flavell, R.A.5
Palmiter, R.D.6
Brinster, R.L.7
-
25
-
-
0035816652
-
Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes
-
Martin CC, Bischof LJ, Bergman B, Hornbuckle LA, Hilliker C, Frigeri C, Wahl D, Svitek CA, Wong R, Goldman JK, et al. Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes. J Biol Chem 2001. 276:25197-25207.
-
(2001)
J Biol Chem
, vol.276
, pp. 25197-25207
-
-
Martin, C.C.1
Bischof, L.J.2
Bergman, B.3
Hornbuckle, L.A.4
Hilliker, C.5
Frigeri, C.6
Wahl, D.7
Svitek, C.A.8
Wong, R.9
Goldman, J.K.10
-
26
-
-
11144356677
-
Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP)
-
Petrolonis AJ, Yang Q, Tummino PJ, Fish SM, Prack AE, Jain S, Parsons TF, Li P, Dales NA, Ge L, et al. Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP). J Biol Chem 2004. 279:13976-13983.
-
(2004)
J Biol Chem
, vol.279
, pp. 13976-13983
-
-
Petrolonis, A.J.1
Yang, Q.2
Tummino, P.J.3
Fish, S.M.4
Prack, A.E.5
Jain, S.6
Parsons, T.F.7
Li, P.8
Dales, N.A.9
Ge, L.10
-
27
-
-
33847620145
-
Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype
-
Wang Y, Martin CC, Oeser JK, Sarkar S, McGuinness OP, Hutton JC, O'Brien RM. Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype. Diabetologia 2007. 50:774-778.
-
(2007)
Diabetologia
, vol.50
, pp. 774-778
-
-
Wang, Y.1
Martin, C.C.2
Oeser, J.K.3
Sarkar, S.4
McGuinness, O.P.5
Hutton, J.C.6
O'Brien, R.M.7
-
28
-
-
20944441042
-
Prevention of diabetes by manipulation of anti-IGRP autoimmunity: High efficiency of a low-affinity peptide
-
Han B, Serra P, Amrani A, Yamanouchi J, Maree AF, Edelstein-Keshet L, Santamaria P. Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide. Nat Med 2005. 11:645-652.
-
(2005)
Nat Med
, vol.11
, pp. 645-652
-
-
Han, B.1
Serra, P.2
Amrani, A.3
Yamanouchi, J.4
Maree, A.F.5
Edelstein-Keshet, L.6
Santamaria, P.7
-
29
-
-
0028288510
-
Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
-
Casciola-Rosen LA, Anhalt G, Rosen A. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 1994. 179:1317-1330.
-
(1994)
J Exp Med
, vol.179
, pp. 1317-1330
-
-
Casciola-Rosen, L.A.1
Anhalt, G.2
Rosen, A.3
|