Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice

Journal of Immunology

Volumn 184, Issue 8, 2010, Pages 4196-4204

  Vincent, Benjamin G ^a   Young, Ellen F ^a   Buntzman, Adam S ^a   Stevens, Rosemary ^a   Kepler, Thomas B ^b   Tisch, Roland M ^a   Frelinger, Jeffrey A ^a   Hess, Paul R ^a,c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; ISLET SPECIFIC GLUCOSE 6 PHOSPHATASE CATALYTIC SUBUNIT RELATED PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; SAPORIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TETRAMER; UNCLASSIFIED DRUG; AUTOANTIGEN; BETA 2 MICROGLOBULIN; EPITOPE; G6PC2 PROTEIN, MOUSE; GLUCOSE 6 PHOSPHATASE; H 2K(K) ANTIGEN; H-2K(K) ANTIGEN; H2 ANTIGEN; HISTOCOMPATIBILITY ANTIGEN H 2D(B); HISTOCOMPATIBILITY ANTIGEN H-2D(B); IMMUNOTOXIN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN; RIBOSOME INACTIVATING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; DIABETES MELLITUS; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PRIORITY JOURNAL; SEQUENCE ANALYSIS; T CELL DEPLETION; ANIMAL; BIOSYNTHESIS; CELL DEATH; CELL MOTION; DISEASE COURSE; FEMALE; GENETICS; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; MOLECULAR MIMICRY; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; PANCREAS ISLET; PATHOLOGY; TRANSGENIC MOUSE;

ANIMALS; AUTOANTIGENS; BETA 2-MICROGLOBULIN; CD8-POSITIVE T-LYMPHOCYTES; CELL DEATH; CELL MOVEMENT; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; EPITOPES, T-LYMPHOCYTE; FEMALE; GLUCOSE-6-PHOSPHATASE; H-2 ANTIGENS; IMMUNOTOXINS; ISLETS OF LANGERHANS; MICE; MICE, INBRED NOD; MICE, SCID; MICE, TRANSGENIC; MOLECULAR MIMICRY; PROTEINS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RIBOSOME INACTIVATING PROTEINS, TYPE 1;

EID: 77952755936     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903931     Document Type: Article

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