A peptidomimetic tight junction modulator to improve regional analgesia

Molecular Pharmaceutics

Volumn 9, Issue 6, 2012, Pages 1785-1794

  Zwanziger, Denise ^a   Hackel, Dagmar ^b   Staat, Christian ^a   Böcker, Alexander ^b   Brack, Alexander ^b   Beyermann, Michael ^a   Rittner, Heike ^b   Blasig, Ingolf E ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

Author keywords

claudin peptide; paracellular modulation; regional analgesia; tight junction

Indexed keywords

ANTINOCICEPTIVE AGENT; CELL PROTEIN; CLAUDIN 1; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ISOFLURANE; PEPTIDE C1C2; PEPTIDOMIMETIC AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BETA SHEET; BLOOD BRAIN BARRIER; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL VACUOLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; HUMAN; HUMAN CELL; HYDROPHILICITY; IN VIVO STUDY; INTERNALIZATION; ION PERMEABILITY; MOLECULAR WEIGHT; NOCICEPTION; NONHUMAN; PAIN THRESHOLD; PERINEURIUM; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; REGIONAL ANESTHESIA; TIGHT JUNCTION;

ANALGESIA; ANIMALS; BLOTTING, WESTERN; CACO-2 CELLS; CELL LINE; CIRCULAR DICHROISM; CLAUDIN-1; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, CONFOCAL; PEPTIDES; PEPTIDOMIMETICS; PERIPHERAL NERVES; RATS; RATS, WISTAR; SCIATIC NERVE; TIGHT JUNCTIONS;

EID: 84862017234     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp3000937     Document Type: Article

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