Permeability characteristics of tetragastrins across intestinal membranes using the Caco-2 monolayer system: Comparison between acylation and application of protease inhibitors

Pharmaceutical Research

Volumn 15, Issue 9, 1998, Pages 1387-1392

  Fujita, Takuya ^a   Kawahara, Iichiro ^a   Quan, Ying Shu ^a   Hattori, Koji ^a   Takenaka, Kayo ^a   Muranishi, Shozo ^a   Yamamoto, Akira ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Caco 2 cells; Chemical modification; Membrane permeability; Tetragastrin

Indexed keywords

ACETYLTETRAGASTRIN; ACYLTETRAGASTRIN; BACITRACIN; CAPROYLTETRAGASTRIN; GABEXATE; PROTEINASE INHIBITOR; TETRAGASTRIN; TETRAGASTRIN DERIVATIVE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG PENETRATION; DRUG STABILITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ACETYLATION; ACYLATION; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; DRUG STABILITY; GABEXATE; HUMANS; INTESTINAL ABSORPTION; INTESTINE, SMALL; MODELS, BIOLOGICAL; SERINE PROTEINASE INHIBITORS; TETRAGASTRIN;

EID: 0031784784     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011997404306     Document Type: Article

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