Hypertonicity regulates the function of human neutrophils by modulating chemoattractant receptor signaling and activating mitogen-activated protein kinase p38

Journal of Clinical Investigation

Volumn 101, Issue 12, 1998, Pages 2768-2779

  Junger, Wolfgang G ^a,c   Hoyt, David B ^a   Davis, Richard E ^a   Herdon Remelius, Crystal ^a   Namiki, Sachiko ^a   Junger, Heidi ^a   Loomis, William ^a   Altman, Amnon ^b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c UCSD MEDICAL CENTER   (United States)

Author keywords

Hypertonic saline resuscitation; Inflammation; MAP kinase; Neutrophil activation and function; Signaling

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CHEMOATTRACTANT; CHEMOTACTIC FACTOR; HYPERTONIC SOLUTION; MITOGEN ACTIVATED PROTEIN KINASE; SUPEROXIDE;

ARTICLE; DEGRANULATION; ENZYME RELEASE; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE ACTIVATION; NEUTROPHIL; OSMOLALITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REPERFUSION; RESUSCITATION; SIGNAL TRANSDUCTION;

EID: 0032525894     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI1354     Document Type: Article

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