메뉴 건너뛰기




Volumn 23, Issue 4, 2012, Pages 412-418

The Xenopus oocyte: A model for studying the metabolic regulation of cancer cell death

Author keywords

Apoptosis; Cancer; Caspase 2; Metabolism; Model system; Xenopus laevis

Indexed keywords

FATTY ACID SYNTHASE; GLUTAMINE; LACTIC ACID; PENTOSE PHOSPHATE;

EID: 84861995187     PISSN: 10849521     EISSN: 10963634     Source Type: Journal    
DOI: 10.1016/j.semcdb.2012.03.015     Document Type: Review
Times cited : (18)

References (71)
  • 1
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • February
    • Warburg O. On the origin of cancer cells. Science 1956, 123(February):309.
    • (1956) Science , vol.123 , pp. 309
    • Warburg, O.1
  • 2
    • 79251517382 scopus 로고    scopus 로고
    • Regulation of cancer cell metabolism. Nature reviews
    • FEBRUARY
    • Cairns R.A., Harris I.S., Mak T.W. Regulation of cancer cell metabolism. Nature reviews. Cancer 2011, 11(February):85.
    • (2011) Cancer , vol.11 , pp. 85
    • Cairns, R.A.1    Harris, I.S.2    Mak, T.W.3
  • 3
    • 34748912615 scopus 로고    scopus 로고
    • Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nature reviews
    • October
    • Menendez J.A., Lupu R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nature reviews. Cancer 2007, 7(October):763.
    • (2007) Cancer , vol.7 , pp. 763
    • Menendez, J.A.1    Lupu, R.2
  • 5
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • March
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144(March):646.
    • (2011) Cell , vol.144 , pp. 646
    • Hanahan, D.1    Weinberg, R.A.2
  • 7
    • 0024513047 scopus 로고
    • Metabolic regulation during early frog development: glycogenic flux in Xenopus oocytes, eggs, and embryos
    • April
    • Dworkin M.B., Dworkin-Rastl E. Metabolic regulation during early frog development: glycogenic flux in Xenopus oocytes, eggs, and embryos. Developmental Biology 1989, 132(April):512.
    • (1989) Developmental Biology , vol.132 , pp. 512
    • Dworkin, M.B.1    Dworkin-Rastl, E.2
  • 8
    • 33745480959 scopus 로고    scopus 로고
    • Study of apoptosis in vitro using the Xenopus egg extract reconstitution system
    • Deming P., Kornbluth S. Study of apoptosis in vitro using the Xenopus egg extract reconstitution system. Methods in Molecular Biology 2006, 322:379.
    • (2006) Methods in Molecular Biology , vol.322 , pp. 379
    • Deming, P.1    Kornbluth, S.2
  • 11
    • 0018386209 scopus 로고
    • Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells
    • April
    • Reitzer L.J., Wice B.M., Kennell D. Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells. The Journal of Biological Chemistry 1979, 254(April):2669.
    • (1979) The Journal of Biological Chemistry , vol.254 , pp. 2669
    • Reitzer, L.J.1    Wice, B.M.2    Kennell, D.3
  • 12
    • 33846002728 scopus 로고    scopus 로고
    • A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
    • January
    • Bonnet S., Archer S.L., Allalunis-Turner J., Haromy A., Beaulieu C., Thlmpson R., et al. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell 2007, 11(January):37.
    • (2007) Cancer Cell , vol.11 , pp. 37
    • Bonnet, S.1    Archer, S.L.2    Allalunis-Turner, J.3    Haromy, A.4    Beaulieu, C.5    Thlmpson, R.6
  • 13
    • 9744221185 scopus 로고    scopus 로고
    • Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak
    • December
    • Majewski N., Nogueira V., Bhaskar P., Coy P.E., Sheen J.E., Gottlob K., et al. Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Molecular Cell 2004, 16(December):819.
    • (2004) Molecular Cell , vol.16 , pp. 819
    • Majewski, N.1    Nogueira, V.2    Bhaskar, P.3    Coy, P.E.4    Sheen, J.E.5    Gottlob, K.6
  • 14
    • 34250179471 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1
    • June
    • Zhao Y., Altman B.J., Coloff J.L., Herman C.E., Jacobs S.R., Wieman H.L., et al. Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Molecular and Cellular Biology 2007, 27(June):4328.
    • (2007) Molecular and Cellular Biology , vol.27 , pp. 4328
    • Zhao, Y.1    Altman, B.J.2    Coloff, J.L.3    Herman, C.E.4    Jacobs, S.R.5    Wieman, H.L.6
  • 15
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • October
    • Datta S.R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., Greenberg M.E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997, 91(October):231.
    • (1997) Cell , vol.91 , pp. 231
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 16
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • October
    • del Peso L., Gonzalez-Garcia M., Page C., Herrera R., Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 1997, 278(October):687.
    • (1997) Science , vol.278 , pp. 687
    • del Peso, L.1    Gonzalez-Garcia, M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 17
    • 33644855216 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
    • March
    • Maurer U., Charvet C., Wagman A.S., Dejardin E., Green D.R. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Molecular Cell 2006, 21(March):749.
    • (2006) Molecular Cell , vol.21 , pp. 749
    • Maurer, U.1    Charvet, C.2    Wagman, A.S.3    Dejardin, E.4    Green, D.R.5
  • 18
    • 33746879141 scopus 로고    scopus 로고
    • Glycolysis inhibition for anticancer treatment
    • August
    • Pelicano H., Martin D.S., Xu R.H., Huang P. Glycolysis inhibition for anticancer treatment. Oncogene 2006, 25(August):4633.
    • (2006) Oncogene , vol.25 , pp. 4633
    • Pelicano, H.1    Martin, D.S.2    Xu, R.H.3    Huang, P.4
  • 19
    • 33846859584 scopus 로고    scopus 로고
    • Glycogen synthesis by the direct or indirect pathways depends on glucose availability: in vivo studies in frog oocytes
    • February
    • Preller A., Kessi E., Ureta T. Glycogen synthesis by the direct or indirect pathways depends on glucose availability: in vivo studies in frog oocytes. FEBS Letters 2007, 581(February):663.
    • (2007) FEBS Letters , vol.581 , pp. 663
    • Preller, A.1    Kessi, E.2    Ureta, T.3
  • 20
    • 34548217873 scopus 로고    scopus 로고
    • Measurement of glycogen synthase activity in crude extracts by CE
    • August
    • Wilson C.A., Preller A., Valenzuela M.A., Ureta T. Measurement of glycogen synthase activity in crude extracts by CE. Electrophoresis 2007, 28(August):2888.
    • (2007) Electrophoresis , vol.28 , pp. 2888
    • Wilson, C.A.1    Preller, A.2    Valenzuela, M.A.3    Ureta, T.4
  • 21
    • 0037404135 scopus 로고    scopus 로고
    • Frog oocyte glycogen synthase: enzyme regulation under in vitro and in vivo conditions
    • May
    • Baez M., Preller A., Ureta T. Frog oocyte glycogen synthase: enzyme regulation under in vitro and in vivo conditions. Archives of Biochemistry and Biophysics 2003, 413(May):9.
    • (2003) Archives of Biochemistry and Biophysics , vol.413 , pp. 9
    • Baez, M.1    Preller, A.2    Ureta, T.3
  • 22
    • 84977297672 scopus 로고
    • Microinjected frog oocytes: a first-rate test tube for studies on metabolism and its control
    • Ureta T., Radojkovic J. Microinjected frog oocytes: a first-rate test tube for studies on metabolism and its control. BioEssays 1985, 2(5):221-226.
    • (1985) BioEssays , vol.2 , Issue.5 , pp. 221-226
    • Ureta, T.1    Radojkovic, J.2
  • 23
    • 0035016679 scopus 로고    scopus 로고
    • Frog oocytes: a living test tube for studies on metabolic regulation
    • January
    • Ureta T., Preller A., Kessi E. Frog oocytes: a living test tube for studies on metabolic regulation. IUBMB Life 2001, 51(January):5.
    • (2001) IUBMB Life , vol.51 , pp. 5
    • Ureta, T.1    Preller, A.2    Kessi, E.3
  • 24
    • 0033049810 scopus 로고    scopus 로고
    • In vivo operation of the pentose phosphate pathway in frog oocytes is limited by NADP+ availability
    • March
    • Preller A., Guixe V., Ureta T. In vivo operation of the pentose phosphate pathway in frog oocytes is limited by NADP+ availability. FEBS Letters 1999, 446(March):149.
    • (1999) FEBS Letters , vol.446 , pp. 149
    • Preller, A.1    Guixe, V.2    Ureta, T.3
  • 25
    • 0021825425 scopus 로고
    • Energy metabolism and pyridine nucleotide levels during Xenopus oocyte maturation
    • Cicirelli M.F., Smith L.D. Energy metabolism and pyridine nucleotide levels during Xenopus oocyte maturation. Development Growth and Differentiation 1985, 27:283.
    • (1985) Development Growth and Differentiation , vol.27 , pp. 283
    • Cicirelli, M.F.1    Smith, L.D.2
  • 26
    • 0018377129 scopus 로고
    • Absence of dorsal-ventral differences in energy metabolism in early embryos of Xenopus laevis
    • January
    • Thoman M., Gerhart J.C. Absence of dorsal-ventral differences in energy metabolism in early embryos of Xenopus laevis. Developmental Biology 1979, 68(January):191.
    • (1979) Developmental Biology , vol.68 , pp. 191
    • Thoman, M.1    Gerhart, J.C.2
  • 27
    • 0025261144 scopus 로고
    • Regulation of carbon flux from amino acids into sugar phosphates in Xenopus embryos
    • March
    • Dworkin M.B., Dworkin-Rastl E. Regulation of carbon flux from amino acids into sugar phosphates in Xenopus embryos. Developmental Biology 1990, 138(March):177.
    • (1990) Developmental Biology , vol.138 , pp. 177
    • Dworkin, M.B.1    Dworkin-Rastl, E.2
  • 28
    • 0023657243 scopus 로고
    • Metabolic regulation during early frog development. Identification of proteins labeled by 32P-glycolytic intermediates
    • December
    • Dworkin M.B., Dworkin-Rastl E. Metabolic regulation during early frog development. Identification of proteins labeled by 32P-glycolytic intermediates. The Journal of Biological Chemistry 1987, 262(December):17038.
    • (1987) The Journal of Biological Chemistry , vol.262 , pp. 17038
    • Dworkin, M.B.1    Dworkin-Rastl, E.2
  • 29
    • 0017119327 scopus 로고
    • Defined nutrient medium for the in vitro matintenance of Xenopus laevis oocytes
    • Eppig J.J., Dumont J.N. Defined nutrient medium for the in vitro matintenance of Xenopus laevis oocytes. In Vitro 1976, 12:418.
    • (1976) In Vitro , vol.12 , pp. 418
    • Eppig, J.J.1    Dumont, J.N.2
  • 30
    • 26244453715 scopus 로고    scopus 로고
    • Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2
    • October
    • Nutt L.K., Margolis S.S., Jensen M., Herman C.E., Dunphy W.E., et al. Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2. Cell 2005, 123(October):89.
    • (2005) Cell , vol.123 , pp. 89
    • Nutt, L.K.1    Margolis, S.S.2    Jensen, M.3    Herman, C.E.4    Dunphy, W.E.5
  • 33
    • 0026000507 scopus 로고
    • In vivo regulation of monomer-tetramer conversion of pyruvate kinase subtype M2 by glucose is mediated via fructose 1,6-bisphosphate
    • Ashizawa K., Willingham M.C., Liang C.M., Cheng S.Y. In vivo regulation of monomer-tetramer conversion of pyruvate kinase subtype M2 by glucose is mediated via fructose 1,6-bisphosphate. The Journal of Biological Chemistry 1991, 266:16842.
    • (1991) The Journal of Biological Chemistry , vol.266 , pp. 16842
    • Ashizawa, K.1    Willingham, M.C.2    Liang, C.M.3    Cheng, S.Y.4
  • 34
    • 0022488438 scopus 로고
    • The inhibitory effect of various fatty acids on aerobic glycolysis in Ehrlich ascites tumour cells
    • Marchut E., Guminska M., Kedryna T. The inhibitory effect of various fatty acids on aerobic glycolysis in Ehrlich ascites tumour cells. Acta Biochimica Polonica 1986, 33:7.
    • (1986) Acta Biochimica Polonica , vol.33 , pp. 7
    • Marchut, E.1    Guminska, M.2    Kedryna, T.3
  • 35
    • 0024261927 scopus 로고
    • Pyruvate kinase type M2 is phosphorylated at tyrosine residues in cells transformed by Rous sarcoma virus
    • December
    • Presek P., Reinacher M., Eigenbrodt E. Pyruvate kinase type M2 is phosphorylated at tyrosine residues in cells transformed by Rous sarcoma virus. FEBS Letters 1988, 242(December):194.
    • (1988) FEBS Letters , vol.242 , pp. 194
    • Presek, P.1    Reinacher, M.2    Eigenbrodt, E.3
  • 36
    • 40749163248 scopus 로고    scopus 로고
    • The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
    • March
    • Christofk H.R., Vander Heiden M.G., Harris M.H., Ramanathan A., Gerszten R.E., Wei R., et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 2008, 452(March):230.
    • (2008) Nature , vol.452 , pp. 230
    • Christofk, H.R.1    Vander Heiden, M.G.2    Harris, M.H.3    Ramanathan, A.4    Gerszten, R.E.5    Wei, R.6
  • 38
    • 77449160135 scopus 로고    scopus 로고
    • PKM2 tyrosine phosphorylation and glutamine metabolism signal a different view of the Warburg effect
    • Dang C.V. PKM2 tyrosine phosphorylation and glutamine metabolism signal a different view of the Warburg effect. Science Signaling 2009, 2:pe75.
    • (2009) Science Signaling , vol.2
    • Dang, C.V.1
  • 43
    • 0015175596 scopus 로고
    • The pathway of glutamine and glutamate oxidation in isolated mitochondria from mammalian cells
    • December
    • Kovacevic Z. The pathway of glutamine and glutamate oxidation in isolated mitochondria from mammalian cells. The Biochemical Journal 1971, 125(December):757.
    • (1971) The Biochemical Journal , vol.125 , pp. 757
    • Kovacevic, Z.1
  • 44
    • 0025850838 scopus 로고
    • Pathway of glutamate oxidation and its regulation in the HuH13 line of human hepatoma cells
    • August
    • Matsuno T. Pathway of glutamate oxidation and its regulation in the HuH13 line of human hepatoma cells. Journal of Cellular Physiology 1991, 148(August):290.
    • (1991) Journal of Cellular Physiology , vol.148 , pp. 290
    • Matsuno, T.1
  • 45
    • 77955281020 scopus 로고    scopus 로고
    • Glutamine addiction: a new therapeutic target in cancer
    • August
    • Wise D.R., Thompson C.B. Glutamine addiction: a new therapeutic target in cancer. Trends in Biochemical Sciences 2010, 35(August):427.
    • (2010) Trends in Biochemical Sciences , vol.35 , pp. 427
    • Wise, D.R.1    Thompson, C.B.2
  • 48
    • 84861982391 scopus 로고
    • Biochemical studies on the energetics of Bufo arenarum segmenting eggs
    • Salomon De Legname H. Biochemical studies on the energetics of Bufo arenarum segmenting eggs. Acta Embryologiae Experimentalis 1969, 3:187.
    • (1969) Acta Embryologiae Experimentalis , vol.3 , pp. 187
    • Salomon De Legname, H.1
  • 49
    • 77956393910 scopus 로고
    • Alteration of the pool of free amino acids during oogenesis, oocyte maturation and embryogenesis of Xenopus laevis and Xenopus borealis
    • Shiokawa K., Tashiro K., Atsuchi Y., Kawazoe Y. Alteration of the pool of free amino acids during oogenesis, oocyte maturation and embryogenesis of Xenopus laevis and Xenopus borealis. Zoological Science 1986, 3:793.
    • (1986) Zoological Science , vol.3 , pp. 793
    • Shiokawa, K.1    Tashiro, K.2    Atsuchi, Y.3    Kawazoe, Y.4
  • 51
    • 0016633240 scopus 로고
    • Utilization of glutamine for energy and protein synthesis by cultured rabbit follicular oocytes
    • February
    • Bae I.H., Foote R.H. Utilization of glutamine for energy and protein synthesis by cultured rabbit follicular oocytes. Experimental Cell Research 1975, 90(February):432.
    • (1975) Experimental Cell Research , vol.90 , pp. 432
    • Bae, I.H.1    Foote, R.H.2
  • 52
    • 0016683863 scopus 로고
    • Carbohydrate and amino acid requirements and ammonia production of rabbit follicular oocytes matured in vitro
    • March
    • Bae I.H., Foote R.H. Carbohydrate and amino acid requirements and ammonia production of rabbit follicular oocytes matured in vitro. Experimental cell research 1975, 91(March):113.
    • (1975) Experimental cell research , vol.91 , pp. 113
    • Bae, I.H.1    Foote, R.H.2
  • 53
    • 0004155427 scopus 로고
    • W.H. Freeman and Company, New York
    • Stryer L. Biochemistry 1988, W.H. Freeman and Company, New York.
    • (1988) Biochemistry
    • Stryer, L.1
  • 54
  • 55
    • 79952280229 scopus 로고    scopus 로고
    • P53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
    • March
    • Jiang P., Du W., Wang X., Mancuso A., Gao X., Wu M., Yang X. p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase. Nature Cell Biology 2011, 13(March):310.
    • (2011) Nature Cell Biology , vol.13 , pp. 310
    • Jiang, P.1    Du, W.2    Wang, X.3    Mancuso, A.4    Gao, X.5    Wu, M.6    Yang, X.7
  • 56
    • 57049132739 scopus 로고    scopus 로고
    • Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
    • December
    • Vaughn A.E., Deshmukh M. Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c. Nature Cell Biology 2008, 10(December):1477.
    • (2008) Nature Cell Biology , vol.10 , pp. 1477
    • Vaughn, A.E.1    Deshmukh, M.2
  • 57
    • 69949101473 scopus 로고    scopus 로고
    • Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
    • September
    • Schafer Z.T., Grassian A.R., Song L., Jiang Z., Gerhart-Hines Z., Irie H.Y., et al. Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment. Nature 2009, 461(September):109.
    • (2009) Nature , vol.461 , pp. 109
    • Schafer, Z.T.1    Grassian, A.R.2    Song, L.3    Jiang, Z.4    Gerhart-Hines, Z.5    Irie, H.Y.6
  • 58
    • 33745246534 scopus 로고    scopus 로고
    • Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome
    • June
    • Chandra D., Bratton S.B., Person M.D., Tian Y., Martin A.G., Ayres M., et al. Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome. Cell 2006, 125(June):1333.
    • (2006) Cell , vol.125 , pp. 1333
    • Chandra, D.1    Bratton, S.B.2    Person, M.D.3    Tian, Y.4    Martin, A.G.5    Ayres, M.6
  • 59
    • 66949181198 scopus 로고    scopus 로고
    • Metabolic control of oocyte apoptosis mediated by 14-3-3zeta-regulated dephosphorylation of caspase-2
    • June
    • Nutt L.K., Buchakjian M.R., Gan E., Darbandi R., Yoon S.Y., Wu J.Q., et al. Metabolic control of oocyte apoptosis mediated by 14-3-3zeta-regulated dephosphorylation of caspase-2. Developmental Cell 2009, 16(June):856.
    • (2009) Developmental Cell , vol.16 , pp. 856
    • Nutt, L.K.1    Buchakjian, M.R.2    Gan, E.3    Darbandi, R.4    Yoon, S.Y.5    Wu, J.Q.6
  • 61
    • 73149109062 scopus 로고    scopus 로고
    • Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis
    • January
    • Nomura D.K., Long J.Z., Niessen S., Hoover H.S., Ng S.W., Cravatt B.F. Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis. Cell 2010, 140(January):49.
    • (2010) Cell , vol.140 , pp. 49
    • Nomura, D.K.1    Long, J.Z.2    Niessen, S.3    Hoover, H.S.4    Ng, S.W.5    Cravatt, B.F.6
  • 62
    • 33745728461 scopus 로고    scopus 로고
    • Fatty acid synthase and cancer: new application of an old pathway
    • June
    • Kuhajda F.P. Fatty acid synthase and cancer: new application of an old pathway. Cancer Research 2006, 66(June):5977.
    • (2006) Cancer Research , vol.66 , pp. 5977
    • Kuhajda, F.P.1
  • 63
    • 57649128306 scopus 로고    scopus 로고
    • Inhibition of fatty-acid synthase induces caspase-8-mediated tumor cell apoptosis by up-regulating DDIT4
    • November
    • Knowles L.M., Yang C., Osterman A., Smith J.W. Inhibition of fatty-acid synthase induces caspase-8-mediated tumor cell apoptosis by up-regulating DDIT4. The Journal of Biological Chemistry 2008, 283(November):31378.
    • (2008) The Journal of Biological Chemistry , vol.283 , pp. 31378
    • Knowles, L.M.1    Yang, C.2    Osterman, A.3    Smith, J.W.4
  • 65
    • 0034650757 scopus 로고    scopus 로고
    • Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts
    • January
    • Pizer E.S., Thupari J., Han W.F., Pinn M.L., Chrest F.J., Frehywot G.L., et al. Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts. Cancer Research 2000, 60(January):213.
    • (2000) Cancer Research , vol.60 , pp. 213
    • Pizer, E.S.1    Thupari, J.2    Han, W.F.3    Pinn, M.L.4    Chrest, F.J.5    Frehywot, G.L.6
  • 66
    • 67649222418 scopus 로고    scopus 로고
    • The mechanism and pattern of yolk consumption provide insight into embryonic nutrition in Xenopus
    • May
    • Jorgensen P., Steen J.A., Steen H., Kirschner M.W. The mechanism and pattern of yolk consumption provide insight into embryonic nutrition in Xenopus. Development 2009, 136(May):1539.
    • (2009) Development , vol.136 , pp. 1539
    • Jorgensen, P.1    Steen, J.A.2    Steen, H.3    Kirschner, M.W.4
  • 67
    • 0024543894 scopus 로고
    • Metabolic regulation during early frog development: flow of glycolytic carbon into phospholipids in Xenopus oocytes and fertilized eggs
    • April
    • Dworkin M.B., Dworkin-Rastl E. Metabolic regulation during early frog development: flow of glycolytic carbon into phospholipids in Xenopus oocytes and fertilized eggs. Developmental Biology 1989, 132(April):524.
    • (1989) Developmental Biology , vol.132 , pp. 524
    • Dworkin, M.B.1    Dworkin-Rastl, E.2
  • 69
    • 0031040469 scopus 로고    scopus 로고
    • Effect of extracellular AMP on cell proliferation and metabolism of breast cancer cell lines with high and low glycolytic rates
    • February
    • Mazurek S., Michel A., Eigenbrodt E. Effect of extracellular AMP on cell proliferation and metabolism of breast cancer cell lines with high and low glycolytic rates. The Journal of Biological Chemistry 1997, 272(February):4941.
    • (1997) The Journal of Biological Chemistry , vol.272 , pp. 4941
    • Mazurek, S.1    Michel, A.2    Eigenbrodt, E.3
  • 70
    • 0031730047 scopus 로고    scopus 로고
    • Metabolic characteristics of different malignant cancer cell lines
    • September-October
    • Mazurek S., Grimm H., Wilker S., Leib S., Eigenbrodt E. Metabolic characteristics of different malignant cancer cell lines. Anticancer Research 1998, 18(September-October):3275.
    • (1998) Anticancer Research , vol.18 , pp. 3275
    • Mazurek, S.1    Grimm, H.2    Wilker, S.3    Leib, S.4    Eigenbrodt, E.5
  • 71
    • 11444255268 scopus 로고
    • On respiratory impairment in cancer cells
    • August
    • Weinhouse S. On respiratory impairment in cancer cells. Science 1956, 124(August):267.
    • (1956) Science , vol.124 , pp. 267
    • Weinhouse, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.