-
1
-
-
0036742053
-
Poor aqueous solubility - An industry wide problem in drug discovery
-
C. Lipinski, Poor aqueous solubility - an industry wide problem in drug discovery, Am. Pharm. Rev. 5 (2002) 82-85.
-
(2002)
Am. Pharm. Rev.
, vol.5
, pp. 82-85
-
-
Lipinski, C.1
-
2
-
-
75549088273
-
Nanoparticles: A personal experience for formulating poorly water soluble drugs
-
E.R. Cooper, Nanoparticles: a personal experience for formulating poorly water soluble drugs, J. Control. Release 141 (2010) 300-302.
-
(2010)
J. Control. Release
, vol.141
, pp. 300-302
-
-
Cooper, E.R.1
-
3
-
-
28444461830
-
Drug nanocrystals of poorly soluble drugs produced by high pressure homogenisation
-
DOI 10.1016/j.ejpb.2005.05.009, PII S0939641105001797
-
C.M. Keck, R.H. Müller, Drug nanocrystals of poorly soluble drugs produced by high pressure homogenisation, Eur. J. Pharm. Biopharm. 62 (2006) 3-16. (Pubitemid 41736019)
-
(2006)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.62
, Issue.1
, pp. 3-16
-
-
Keck, C.M.1
Muller, R.H.2
-
4
-
-
4544383493
-
Nanosuspensions in drug delivery
-
DOI 10.1038/nrd1494
-
B.E. Rabinow, Nanosuspensions in drug delivery, Nat. Rev. Drug Discov. 3 (2004) 785-796. (Pubitemid 39242830)
-
(2004)
Nature Reviews Drug Discovery
, vol.3
, Issue.9
, pp. 785-796
-
-
Rabinow, B.E.1
-
5
-
-
42549152846
-
Drug nanocrystals for the formulation of poorly soluble drugs and its application as a potential drug delivery system
-
L. Gao, D. Zhang, M. Chen, Drug nanocrystals for the formulation of poorly soluble drugs and its application as a potential drug delivery system, J. Nanopart. Res. 10 (2008) 845-862.
-
(2008)
J. Nanopart. Res.
, vol.10
, pp. 845-862
-
-
Gao, L.1
Zhang, D.2
Chen, M.3
-
6
-
-
0029080002
-
Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs
-
G.G. Liversidge, K.C. Cundy, Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs, Int. J. Pharm. 125 (1995) 91-97.
-
(1995)
Int. J. Pharm.
, vol.125
, pp. 91-97
-
-
Liversidge, G.G.1
Cundy, K.C.2
-
7
-
-
0033965872
-
Preparation of a clofazimine nanosuspension for intravenous use and evaluation of its therapeutic efficacy in murine Mycobacterium avium infection
-
K. Peters, S. Leitzke, J. Diederichs, K. Borner, H. Hahn, R.H. Müller, S. Ehlers, Preparation of a clofazimine nanosuspension for intravenous use and evaluation of its therapeutic efficacy in murine Mycobacterium avium infection, J. Antimicrob. Chemother. 45 (2000) 77-83. (Pubitemid 30060237)
-
(2000)
Journal of Antimicrobial Chemotherapy
, vol.45
, Issue.1
, pp. 77-83
-
-
Peters, K.1
Leitzke, S.2
Diederichs, J.E.3
Borner, K.4
Hahn, H.5
Muller, R.H.6
Ehlers, S.7
-
8
-
-
0036020063
-
Eudragit RS100 nanosuspensions for the ophthalmic controlled delivery of ibuprofen
-
P. Rosario, B. Claudio, F. Piera, M. Adriana, P. Antonina, P. Giovanni, Eudragit RS100 nanosuspensions for the ophthalmic controlled delivery of ibuprofen, Eur. J. Pharm. Sci. 16 (2002) 53-61.
-
(2002)
Eur. J. Pharm. Sci.
, vol.16
, pp. 53-61
-
-
Rosario, P.1
Claudio, B.2
Piera, F.3
Adriana, M.4
Antonina, P.5
Giovanni, P.6
-
9
-
-
0036176196
-
Production and characterization of a budesonide nanosuspension for pulmonary administration
-
DOI 10.1023/A:1014276917363
-
C. Jacobs, R.H. Müller, Production and characterization of a budesonide nanosuspension for pulmonary administration, Pharm. Res. 19 (2002) 189-194. (Pubitemid 34165405)
-
(2002)
Pharmaceutical Research
, vol.19
, Issue.2
, pp. 189-194
-
-
Jacobs, C.1
Muller, R.H.2
-
10
-
-
0035937599
-
Nanosuspensions as particulate drug formulations in therapy: Rationale for development and what we can expect for the future
-
DOI 10.1016/S0169-409X(00)00118-6, PII S0169409X00001186
-
R.H. Müller, C. Jacobs, O. Kayser, Nanosuspensions as particulate drug formulations in therapy: rationale for development and what we can expect for the future, Adv. Drug Deliv. Rev. 47 (2001) 3-19. (Pubitemid 32209229)
-
(2001)
Advanced Drug Delivery Reviews
, vol.47
, Issue.1
, pp. 3-19
-
-
Muller, R.H.1
Jacobs, C.2
Kayser, O.3
-
11
-
-
53949092998
-
Top-down production of drug nanocrystals: Nanosuspension stabilization, miniaturization and transformation into solid products
-
B. Van Eerdenbrugh, G. Van den Mooter, P. Augustijns, Top-down production of drug nanocrystals: nanosuspension stabilization, miniaturization and transformation into solid products, Int. J. Pharm. 364 (2008) 64-75.
-
(2008)
Int. J. Pharm.
, vol.364
, pp. 64-75
-
-
Van Eerdenbrugh, B.1
Van Den Mooter, G.2
Augustijns, P.3
-
12
-
-
0037312695
-
Nanosizing: A formulation approach for poorly-water-soluble compounds
-
DOI 10.1016/S0928-0987(02)00251-8
-
E. Merisko-Liversidge, G.G. Liversidge, E.R. Cooper, Nanosizing: a formulation approach for poorly-water-soluble compounds, Eur. J. Pharm. Sci. 18 (2003) 113-120. (Pubitemid 36184748)
-
(2003)
European Journal of Pharmaceutical Sciences
, vol.18
, Issue.2
, pp. 113-120
-
-
Merisko-Liversidge, E.1
Liversidge, G.G.2
Cooper, E.R.3
-
13
-
-
1842559836
-
Nanoparticle Engineering Processes for Enhancing the Dissolution Rates of Poorly Water Soluble Drugs
-
DOI 10.1081/DDC-120030422
-
J. Hu, K.P. Johnston, R.O. Williams, Nanoparticle engineering processes for enhancing the dissolution rates of poorly water soluble drugs, Drug Dev. Ind. Pharm. 30 (2004) 233-245. (Pubitemid 38451748)
-
(2004)
Drug Development and Industrial Pharmacy
, vol.30
, Issue.3
, pp. 233-245
-
-
Hu, J.1
Johnston, K.P.2
Williams III, R.O.3
-
14
-
-
69749103682
-
Nanocrystal technology, drug delivery and clinical applications
-
J.A.H. Junghanns, R.H. Müller, Nanocrystal technology, drug delivery and clinical applications, Int. J. Nanomedicine 3 (2008) 295-310.
-
(2008)
Int. J. Nanomedicine
, vol.3
, pp. 295-310
-
-
Junghanns, J.A.H.1
Müller, R.H.2
-
15
-
-
0025304474
-
Mechanisms of creatine kinase release from isolated rat skeletal muscles damaged by propylene glycol and ethanol
-
DOI 10.1002/jps.2600790506
-
G.A. Brazeau, H.L. Fung, Mechanisms of creatine kinase release from isolated rat skeletal muscles damaged by propylene glycol and ethanol, J. Pharm. Sci. 79 (1990) 393-397. (Pubitemid 20152168)
-
(1990)
Journal of Pharmaceutical Sciences
, vol.79
, Issue.5
, pp. 393-397
-
-
Brazeau, G.A.1
Fung, H.-L.2
-
16
-
-
0016980286
-
Polyethylene glycol as a solvent for diazepam: Bioavailability and clinical effects after intramuscular administration, comparison of oral, intramuscular and rectal administration, and precipitation from intravenous solutions
-
K. Korttila, A. Sothman, P. Andersson, Polyethylene glycol as a solvent for diazepam: bioavailability and clinical effects after intramuscular administration, comparison of oral, intramuscular and rectal administration, and precipitation from intravenous solutions, Acta Pharmacol. Toxicol. (Copenh) 39 (1976) 104-117.
-
(1976)
Acta Pharmacol. Toxicol. (Copenh)
, vol.39
, pp. 104-117
-
-
Korttila, K.1
Sothman, A.2
Andersson, P.3
-
17
-
-
0018749130
-
Experiments on the toxic, sedative and muscle relaxant potency of various drug solvents in mice
-
DOI 10.1016/0163-7258(79)90119-0
-
R. Budden, U.G. Kuhl, J. Bahlsen, Experiments on toxic, sedative and muscle relaxant potency of various drug solvents in mice, Pharmacol. Ther. 5 (1979) 467-474. (Pubitemid 9227944)
-
(1979)
Pharmacology and Therapeutics
, vol.5
, Issue.1-3
, pp. 467-474
-
-
Budden, R.1
Kuehl, U.G.2
Bahlsen, J.3
-
18
-
-
77953257993
-
Targeted cancer therapy with novel high drug-loading nanocrystals
-
F. Liu, J.Y. Park, Y. Zhang, C. Conwell, Y. Liu, S.R. Bathula, L. Huang, Targeted cancer therapy with novel high drug-loading nanocrystals, J. Pharm. Sci. 99 (2010) 3542-3551.
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 3542-3551
-
-
Liu, F.1
Park, J.Y.2
Zhang, Y.3
Conwell, C.4
Liu, Y.5
Bathula, S.R.6
Huang, L.7
-
19
-
-
34250879747
-
Itraconazole IV nanosuspension enhances efficacy through altered pharmacokinetics in the rat
-
DOI 10.1016/j.ijpharm.2007.02.030, PII S0378517307002062
-
B. Rabinow, J. Kipp, P. Papadopoulos, J. Wong, J. Glosson, J. Gass, C.S. Sun, T. Wielgos, R. White, C. Cook, K. Barker, K. Wood, Itraconazole IV nanosuspension enhances efficacy through altered pharmacokinetics in the rat, Int. J. Pharm. 339 (2007) 251-260. (Pubitemid 46977603)
-
(2007)
International Journal of Pharmaceutics
, vol.339
, Issue.1-2
, pp. 251-260
-
-
Rabinow, B.1
Kipp, J.2
Papadopoulos, P.3
Wong, J.4
Glosson, J.5
Gass, J.6
Sun, C.-S.7
Wielgos, T.8
White, R.9
Cook, C.10
Barker, K.11
Wood, K.12
-
20
-
-
34548049483
-
Nanosizing - Oral formulation development and biopharmaceutical evaluation
-
DOI 10.1016/j.addr.2007.05.003, PII S0169409X0700083X
-
F. Kesisoglou, S. Panmai, Y. Wu, Nanosizing - oral formulation development and biopharmaceutical evaluation, Adv. Drug Deliv. Rev. 59 (2007) 631-644. (Pubitemid 47285408)
-
(2007)
Advanced Drug Delivery Reviews
, vol.59
, Issue.7
, pp. 631-644
-
-
Kesisoglou, F.1
Panmai, S.2
Wu, Y.3
-
21
-
-
59949091205
-
Diclofenac-loaded biopolymeric nanosuspensions for ophthalmic application
-
S.M. Agnihotri, P.R. Vavia, Diclofenac-loaded biopolymeric nanosuspensions for ophthalmic application, Nanomedicine 5 (2009) 90-95.
-
(2009)
Nanomedicine
, vol.5
, pp. 90-95
-
-
Agnihotri, S.M.1
Vavia, P.R.2
-
22
-
-
0028824401
-
Drug particle size reduction for decreasing gastric irritancy and enhancing absorption of naproxen in rats
-
G.G. Liversidge, P. Conzentino, Drug particle size reduction for decreasing gastric irritancy and enhancing absorption of naproxen in rats, Int. J. Pharm. 125 (1995) 309-313.
-
(1995)
Int. J. Pharm.
, vol.125
, pp. 309-313
-
-
Liversidge, G.G.1
Conzentino, P.2
-
23
-
-
79957861493
-
Nanosizing for oral and parenteral drug delivery: A perspective on formulating poorly-water soluble compounds using wet media milling technology
-
E. Merisko-Liversidge, G.G. Liversidge, Nanosizing for oral and parenteral drug delivery: a perspective on formulating poorly-water soluble compounds using wet media milling technology, Adv. Drug Deliv. Rev. 30 (2011) 427-440.
-
(2011)
Adv. Drug Deliv. Rev.
, vol.30
, pp. 427-440
-
-
Merisko-Liversidge, E.1
Liversidge, G.G.2
-
24
-
-
0033178415
-
Lab-scale production unit design for nanosuspensions of sparingly soluble cytotoxic drugs
-
B.H.L. Böhm, R.H. Müller, Lab-scale production unit design for nanosuspensions of sparingly soluble cytotoxic drugs, Pharm. Sci. Technol. Today 2 (1999) 336-339.
-
(1999)
Pharm. Sci. Technol. Today
, vol.2
, pp. 336-339
-
-
Böhm, B.H.L.1
Müller, R.H.2
-
25
-
-
0742287242
-
Comparative safety of amphotericin B lipid complex and amphotericin B deoxycholate as aerosolized antifungal prophylaxis in lung-transplant recipients
-
DOI 10.1097/01.TP.0000101516.08327.A9
-
R.H. Drew, E. Dodds Ashley, D.K. Benjamin Jr., R. Duane Davis, S.M. Palmer, J.R. Perfect, Comparative safety of amphotericin B lipid complex and amphotericin B deoxycholate as aerosolized antifungal prophylaxis in lung-transplant recipients, Transplantation 77 (2004) 232-237. (Pubitemid 38155752)
-
(2004)
Transplantation
, vol.77
, Issue.2
, pp. 232-237
-
-
Drew, R.H.1
Ashley, E.D.2
Benjamin Jr., D.K.3
Davis, R.D.4
Palmer, S.M.5
Perfect, J.R.6
-
26
-
-
0029148693
-
The physiologic effects of inhaled amphotericin B
-
J. Dubois, T. Bartter, J. Gryn, M.R. Pratter, The physiologic effects of inhaled amphotericin B, Chest 108 (1995) 750-753.
-
(1995)
Chest
, vol.108
, pp. 750-753
-
-
Dubois, J.1
Bartter, T.2
Gryn, J.3
Pratter, M.R.4
-
27
-
-
0035881350
-
Safety of aerosolized amphotericin B lipid complex in lung transplant recipients
-
S.M. Palmer, R.H. Drew, J.D. Whitehouse, V.F. Tapson, R.D. Davis, R.R. McConnell, S.S. Kanj, J.R. Perfect, Safety of aerosolized amphotericin B lipid complex in lung transplant recipients, Transplantation 72 (2001) 545-548. (Pubitemid 32769650)
-
(2001)
Transplantation
, vol.72
, Issue.3
, pp. 545-548
-
-
Palmer, S.M.1
Drew, R.H.2
Whitehouse, J.D.3
Tapson, V.F.4
Duane, D.R.5
McConnell, R.R.6
Kanj, S.S.7
Perfect, J.R.8
-
28
-
-
0032935231
-
Formulation of a protein with propellant HFA 134a for aerosol delivery
-
DOI 10.1016/S0928-0987(98)00015-3, PII S0928098798000153
-
R.O. Williams III, J. Liu, Formulation of a protein with propellant HFA 134a for aerosol delivery, Eur. J. Pharm. Sci. 7 (1999) 137-144. (Pubitemid 29056236)
-
(1999)
European Journal of Pharmaceutical Sciences
, vol.7
, Issue.2
, pp. 137-144
-
-
Williams, I.R.O.1
Liu, J.2
-
29
-
-
0026965892
-
Pharmaceutical evaluation of a new spacer device for delivery of metered-dose inhalers to infants and young children
-
I.C. Ashurst, C.V. Ambrose, D.J. Russell, Pharmaceutical evaluation of a new spacer device for delivery of metered-dose inhalers to infants and young children, J. Aerosol Sci. 23 (1992) 499-502.
-
(1992)
J. Aerosol Sci.
, vol.23
, pp. 499-502
-
-
Ashurst, I.C.1
Ambrose, C.V.2
Russell, D.J.3
-
30
-
-
0032950123
-
Physical stability of ethyl diatrizoate nanocrystalline suspension in steam sterilization
-
G.C. Na, H.J. Stevens, B. Yuan, N. Rajagopalan, Physical stability of ethyl diatrizoate nanocrystalline suspension in steam sterilization, Pharm. Res. 16 (1999) 569-574. (Pubitemid 29191304)
-
(1999)
Pharmaceutical Research
, vol.16
, Issue.4
, pp. 569-574
-
-
Na, G.C.1
Stevens Jr., H.J.2
Yuan, B.O.3
Rajagopalan, N.4
-
31
-
-
68649106338
-
In vitro and in vivo antitumor activity of oridonin nanosuspension
-
H. Lou, X. Zhang, L. Gao, F. Feng, J. Wang, X. Wei, Z. Yu, D. Zhang, Q. Zhang, In vitro and in vivo antitumor activity of oridonin nanosuspension, Int. J. Pharm. 379 (2009) 181-186.
-
(2009)
Int. J. Pharm.
, vol.379
, pp. 181-186
-
-
Lou, H.1
Zhang, X.2
Gao, L.3
Feng, F.4
Wang, J.5
Wei, X.6
Yu, Z.7
Zhang, D.8
Zhang, Q.9
-
32
-
-
41349120910
-
Studies on pharmacokinetics and tissue distribution of oridonin nanosuspensions
-
L. Gao, D. Zhang, M. Chen, C. Duan, W. Dai, L. Jia, W. Zhao, Studies on pharmacokinetics and tissue distribution of oridonin nanosuspensions, Int. J. Pharm. 355 (2008) 321-327.
-
(2008)
Int. J. Pharm.
, vol.355
, pp. 321-327
-
-
Gao, L.1
Zhang, D.2
Chen, M.3
Duan, C.4
Dai, W.5
Jia, L.6
Zhao, W.7
-
33
-
-
0034996764
-
Long circulating and target-specific nanoparticles: Theory to practice
-
S.M. Moghimi, A.C. Hunter, J.C. Murray, Long circulating and target-specific nanoparticles: theory to practice, Pharmacol. Rev. 53 (2001) 283-381.
-
(2001)
Pharmacol. Rev.
, vol.53
, pp. 283-381
-
-
Moghimi, S.M.1
Hunter, A.C.2
Murray, J.C.3
-
34
-
-
58249109448
-
Formulation and pharmacokinetic evaluation of an asulacrine nanocrystalline suspension for intravenous delivery
-
S. Ganta, J.W. Paxton, B.C. Baguley, S. Garg, Formulation and pharmacokinetic evaluation of an asulacrine nanocrystalline suspension for intravenous delivery, Int. J. Pharm. 367 (2009) 179-186.
-
(2009)
Int. J. Pharm.
, vol.367
, pp. 179-186
-
-
Ganta, S.1
Paxton, J.W.2
Baguley, B.C.3
Garg, S.4
-
35
-
-
34547781194
-
A formulation comparison, using a solution and different nanosuspensions of a poorly soluble compound
-
DOI 10.1016/j.ejpb.2007.02.008, PII S0939641107000501
-
K. Sigfridsson, S. Forssén, P. Holländer, U. Skantze, J. de Verdier, A formulation comparison, using a solution and different nanosuspensions of a poorly soluble compound, Eur. J. Pharm. Biopharm. 67 (2007) 540-547. (Pubitemid 47225040)
-
(2007)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.67
, Issue.2
, pp. 540-547
-
-
Sigfridsson, K.1
Forssen, S.2
Hollander, P.3
Skantze, U.4
De Verdier, J.5
-
36
-
-
71049183092
-
Particle size reduction for improvement of oral absorption absorption of the poorly soluble drug UG558 in rats during early development
-
K. Sigfridsson, A.J. Lundqvist, M. Strimfors, Particle size reduction for improvement of oral absorption absorption of the poorly soluble drug UG558 in rats during early development, Drug Dev. Ind. Pharm. 35 (2009) 1479-1486.
-
(2009)
Drug Dev. Ind. Pharm.
, vol.35
, pp. 1479-1486
-
-
Sigfridsson, K.1
Lundqvist, A.J.2
Strimfors, M.3
-
37
-
-
79952961931
-
Folate-targeted drug-delivery systems prepared by nanocomminution
-
S. Kim, J. Lee, Folate-targeted drug-delivery systems prepared by nanocomminution, Drug Dev. Ind. Pharm. 37 (2011) 131-138.
-
(2011)
Drug Dev. Ind. Pharm.
, vol.37
, pp. 131-138
-
-
Kim, S.1
Lee, J.2
-
38
-
-
38349162256
-
Preparation and characterization of intravenously injectable nimodipine nanosuspension
-
R. Xiong, W. Lu, J. Li, P. Wang, R. Xu, T. Chen, Preparation and characterization of intravenously injectable nimodipine nanosuspension, Int. J. Pharm. 350 (2008) 338-343.
-
(2008)
Int. J. Pharm.
, vol.350
, pp. 338-343
-
-
Xiong, R.1
Lu, W.2
Li, J.3
Wang, P.4
Xu, R.5
Chen, T.6
-
39
-
-
78650778104
-
Preparation and characterization of intravenously injectable curcumin nanosuspension
-
Y. Gao, Z. Li, M. Sun, C. Guo, A. Yu, Y. Xi, J. Cui, H. Lou, G. Zhai, Preparation and characterization of intravenously injectable curcumin nanosuspension, Drug Deliv. 18 (2011) 131-142.
-
(2011)
Drug Deliv.
, vol.18
, pp. 131-142
-
-
Gao, Y.1
Li, Z.2
Sun, M.3
Guo, C.4
Yu, A.5
Xi, Y.6
Cui, J.7
Lou, H.8
Zhai, G.9
-
40
-
-
0342897023
-
Nanosuspensions for the formulation of poorly soluble drugs. I. Preparation by a size-reduction technique
-
DOI 10.1016/S0378-5173(97)00311-6, PII S0378517397003116
-
R.H. Müller, K. Peters, Nanosuspensions for the formulation of poorly soluble drugs I. Preparation by a size-reduction technique, Int. J. Pharm. 160 (1998) 229-237. (Pubitemid 28083096)
-
(1998)
International Journal of Pharmaceutics
, vol.160
, Issue.2
, pp. 229-237
-
-
Muller, R.H.1
Peters, K.2
-
41
-
-
52949128719
-
Comparison of nanosuspensions and hydroxypropyl-b-cyclodextrin complex of melarsoprol: Pharmacokinetics and tissue distribution in mice
-
S.B. Zirar, A. Astier, M. Muchow, S. Gibaud, Comparison of nanosuspensions and hydroxypropyl-b-cyclodextrin complex of melarsoprol: pharmacokinetics and tissue distribution in mice, Eur. J. Pharm. Biopharm. 70 (2008) 649-656.
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.70
, pp. 649-656
-
-
Zirar, S.B.1
Astier, A.2
Muchow, M.3
Gibaud, S.4
-
42
-
-
33646515151
-
A phase I study with oral SU5416 in patients with advanced solid tumors: A drug inducing its clearance
-
M. Salzberg, M. Pless, C. Rochlitz, K. Ambrus, P. Scigalla, R. Herrmann, A phase I study with oral SU5416 in patients with advanced solid tumors: a drug inducing its clearance, Invest. New Drugs 24 (2006) 299-304.
-
(2006)
Invest. New Drugs
, vol.24
, pp. 299-304
-
-
Salzberg, M.1
Pless, M.2
Rochlitz, C.3
Ambrus, K.4
Scigalla, P.5
Herrmann, R.6
-
43
-
-
0347625573
-
The Pharmacokinetics of Nebulized Nanocrystal Budesonide Suspension in Healthy Volunteers
-
DOI 10.1177/0091270003261490
-
W.K. Kraft, B. Steiger, D. Beussink, J.N. Quiring, N. Fitzgerald, H.E. Greenberg, S.A. Waldman, The pharmacokinetics of nebulized nanocrystal budesonide suspension in healthy volunteers, J. Clin. Pharmacol. 44 (2004) 67-72. (Pubitemid 38005095)
-
(2004)
Journal of Clinical Pharmacology
, vol.44
, Issue.1
, pp. 67-72
-
-
Kraft, W.K.1
Steiger, B.2
Beussink, D.3
Quiring, J.N.4
Fitzgerald, N.5
Greenberg, H.E.6
Waldman, S.A.7
-
44
-
-
34248667006
-
Murine airway histology and intracellular uptake of inhaled amorphous itraconazole
-
DOI 10.1016/j.ijpharm.2007.02.014, PII S0378517307001615
-
J.M. Vaughn, N.P. Wiederhold, J.T. McConville, J.J. Coalson, R.L. Talbert, D.S. Burgess, K.P. Johnston, R.O. Williams III, J.I. Peters, Murine airway histology and intracellular uptake of inhaled amorphous itraconazole, Int. J. Pharm. 338 (2007) 219-224. (Pubitemid 46777243)
-
(2007)
International Journal of Pharmaceutics
, vol.338
, Issue.1-2
, pp. 219-224
-
-
Vaughn, J.M.1
Wiederhold, N.P.2
McConville, J.T.3
Coalson, J.J.4
Talbert, R.L.5
Burgess, D.S.6
Johnston, K.P.7
Williams III, R.O.8
Peters, J.I.9
-
45
-
-
33646841349
-
Single dose and multiple dose studies of itraconazole nanoparticles
-
DOI 10.1016/j.ejpb.2006.01.006, PII S0939641106000063
-
J.M. Vaughn, J.T. McConville, D. Burgess, J.I. Peters, K.P. Johnston, R.L. Talbert, R.O. Williams III, Single dose and multiple dose studies of itraconazole nanoparticles, Eur. J. Pharm. Biopharm. 63 (2006) 95-102. (Pubitemid 43776206)
-
(2006)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.63
, Issue.2
, pp. 95-102
-
-
Vaughn, J.M.1
McConville, J.T.2
Burgess, D.3
Peters, J.I.4
Johnston, K.P.5
Talbert, R.L.6
Williams III, R.O.7
-
46
-
-
33645792333
-
In vivo efficacy of aerosolized nanostructured itraconazole formulations for prevention of invasive pulmonary aspergillosis
-
B.J. Hoeben, D.S. Burgess, J.T. McConville, L.K. Najvar, R.L. Talbert, J.I. Peters, N.P. Wiederhold, B.L. Frei, J.R. Graybill, R. Bocanegra, K.A. Overhoff, P. Sinswat, K.P. Johnston, R.O. Williams III, In vivo efficacy of aerosolized nanostructured itraconazole formulations for prevention of invasive pulmonary aspergillosis, Antimicrob. Agents Chemother. 50 (2006) 1552-1554.
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 1552-1554
-
-
Hoeben, B.J.1
Burgess, D.S.2
McConville, J.T.3
Najvar, L.K.4
Talbert, R.L.5
Peters, J.I.6
Wiederhold, N.P.7
Frei, B.L.8
Graybill, J.R.9
Bocanegra, R.10
Overhoff, K.A.11
Sinswat, P.12
Johnston, K.P.13
Williams III, R.O.14
-
47
-
-
34249995115
-
Aerosolized nanostructured itraconazole as prophylaxis against invasive pulmonary aspergillosis
-
DOI 10.1016/j.jinf.2007.01.014, PII S0163445307000424
-
C.A. Alvarez, N.P. Wiederhold, J.T. McConville, J.I. Peters, L.K. Najvar, J.R. Graybill, J.J. Coalson, R.L. Talbert, D.S. Burgess, R. Bocanegra, K.P. Johnston, R.O. Williams III, Aerosolized nanostructured itraconazole as prophylaxis against invasive pulmonary aspergillosis, J. Infect. 55 (2007) 68-74. (Pubitemid 46888077)
-
(2007)
Journal of Infection
, vol.55
, Issue.1
, pp. 68-74
-
-
Alvarez, C.A.1
Wiederhold, N.P.2
McConville, J.T.3
Peters, J.I.4
Najvar, L.K.5
Graybill, J.R.6
Coalson, J.J.7
Talbert, R.L.8
Burgess, D.S.9
Bocanegra, R.10
Johnston, K.P.11
Williams III, R.O.12
-
48
-
-
57049157156
-
Pharmacokinetics of a novel submicron budesonide dispersion for nebulized delivery in asthma
-
S.B. Shrewsbury, A.P. Bosco, P.S. Uster, Pharmacokinetics of a novel submicron budesonide dispersion for nebulized delivery in asthma, Int. J. Pharm. 365 (2009) 12-17.
-
(2009)
Int. J. Pharm.
, vol.365
, pp. 12-17
-
-
Shrewsbury, S.B.1
Bosco, A.P.2
Uster, P.S.3
-
49
-
-
0027403986
-
Surface modification of i.v. injectable biodegradable nanoparticles with poloxamer polymers and poloxamine 908
-
DOI 10.1016/0378-5173(93)90304-X
-
R.H. Müller, K.H. Wallis, Surface modification of i.v. injectable biodegradable nanoparticles with poloxamer polymers and poloxamine 908, Int. J. Pharm. 89 (1993) 25-31. (Pubitemid 23008588)
-
(1993)
International Journal of Pharmaceutics
, vol.89
, Issue.1
, pp. 25-31
-
-
Muller, R.H.1
Wallis, K.H.2
-
50
-
-
0037072566
-
Nanoparticles in cancer therapy and diagnosis
-
DOI 10.1016/S0169-409X(02)00044-3, PII S0169409X02000443
-
I. Brigger, C. Dubernet, P. Couvreur, Nanoparticles in cancer therapy and diagnosis, Adv. Drug Deliv. Rev. 54 (2002) 631-651. (Pubitemid 35247520)
-
(2002)
Advanced Drug Delivery Reviews
, vol.54
, Issue.5
, pp. 631-651
-
-
Brigger, I.1
Dubernet, C.2
Couvreur, P.3
-
51
-
-
0033805179
-
In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs
-
J.B. Dressman, C. Reppas, In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs, Eur. J. Pharm. Sci. 11 (2000) 73-80.
-
(2000)
Eur. J. Pharm. Sci.
, vol.11
, pp. 73-80
-
-
Dressman, J.B.1
Reppas, C.2
-
52
-
-
77953683770
-
Targeting nanoparticles to cancer
-
M. Wang, M. Thanou, Targeting nanoparticles to cancer, Pharmacol. Res. 62 (2010) 90-99.
-
(2010)
Pharmacol. Res.
, vol.62
, pp. 90-99
-
-
Wang, M.1
Thanou, M.2
-
53
-
-
78650679438
-
Preparation of a chemically stable quercetin formulation using nanosuspension technology
-
L. Gao, G. Liu, X. Wang, F. Liu, Y. Xu, J. Ma, Preparation of a chemically stable quercetin formulation using nanosuspension technology, Int. J. Pharm. 404 (2011) 231-237.
-
(2011)
Int. J. Pharm.
, vol.404
, pp. 231-237
-
-
Gao, L.1
Liu, G.2
Wang, X.3
Liu, F.4
Xu, Y.5
Ma, J.6
-
54
-
-
0037189994
-
Enhanced drug dissolution using evaporative precipitation into aqueous solution
-
M. Sarkari, J. Brown, X. Chen, S. Swinnea, R.O. Williams III, K.P. Johnston, Enhanced drug dissolution using evaporative precipitation into aqueous solution, Int. J. Pharm. 243 (2002) 17-31.
-
(2002)
Int. J. Pharm.
, vol.243
, pp. 17-31
-
-
Sarkari, M.1
Brown, J.2
Chen, X.3
Swinnea, S.4
Williams III, R.O.5
Johnston, K.P.6
-
55
-
-
70350639421
-
Preparation of fenofibrate nanosuspension and study of its pharmacokinetic behavior in rats
-
X. Li, L. Gu, Y. Xu, Y. Wang, Preparation of fenofibrate nanosuspension and study of its pharmacokinetic behavior in rats, Drug Dev. Ind. Pharm. 35 (2009) 827-833.
-
(2009)
Drug Dev. Ind. Pharm.
, vol.35
, pp. 827-833
-
-
Li, X.1
Gu, L.2
Xu, Y.3
Wang, Y.4
-
56
-
-
34547863131
-
Pharmacokinetic evaluation of oral fenofibrate nanosuspensions and SLN in comparison to conventional suspensions of micronized drug
-
DOI 10.1016/j.addr.2007.04.005, PII S0169409X07000397, Lipid Nanoparticles: Recent Advances
-
A. Hanafy, H. Spahn-Langguth, G. Vergnault, P. Grenier, M. Tubic Grozdanis, T. Lenhardt, P. Langguth, Pharmacokinetic evaluation of oral fenofibrate nanosuspensions and SLN in comparison to conventional suspensions of micronized drug, Adv. Drug Deliv. Rev. 59 (2007) 419-426. (Pubitemid 47260709)
-
(2007)
Advanced Drug Delivery Reviews
, vol.59
, Issue.6
, pp. 419-426
-
-
Hanafy, A.1
Spahn-Langguth, H.2
Vergnault, G.3
Grenier, P.4
Tubic, G.M.5
Lenhardt, T.6
Langguth, P.7
-
57
-
-
0037142222
-
In vivo evaluation of matrix pellets containing nanocrystalline ketoprofen
-
DOI 10.1016/S0378-5173(02)00114-X, PII S037851730200114X
-
G.J. Vergote, C. Vervaet, I. Van Driessche, S. Hoste, S. De Smedt, J. Demeester, R.A. Jain, S. Ruddy, J.P. Remon, In vivo evaluation of matrix pellets containing nanocrystalline ketoprofen, Int. J. Pharm. 240 (2002) 79-84. (Pubitemid 34607704)
-
(2002)
International Journal of Pharmaceutics
, vol.240
, Issue.1-2
, pp. 79-84
-
-
Vergote, G.J.1
Vervaet, C.2
Van Driessche, I.3
Hoste, S.4
De Smedt, S.5
Demeester, J.6
Jain, R.A.7
Ruddy, S.8
Remon, J.P.9
-
58
-
-
42149190687
-
Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats
-
DOI 10.1111/j.1742-7843.2008.00213.x
-
S. Ghosh, P. Chiang, J.L. Wahlstrom, H. Fujiwara, J.G. Selbo, S.L. Roberds, Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats, Basic Clin. Pharmacol. Toxicol. 102 (2008) 453-458. (Pubitemid 351537788)
-
(2008)
Basic and Clinical Pharmacology and Toxicology
, vol.102
, Issue.5
, pp. 453-458
-
-
Ghosh, S.1
Chiang, P.-C.2
Wahlstrom, J.L.3
Fujiwara, H.4
Selbo, J.G.5
Roberds, S.L.6
-
59
-
-
16244398708
-
Nanosuspension formulations for low-soluble drugs: Pharmacokinetic evaluation using spironolactone as model compound
-
DOI 10.1081/DDC-52182
-
P. Langguth, A. Hanafy, D. Frenzel, P. Grenier, A. Nhamias, T. Ohlig, G. Vergnault, H. Spahn-Langguth, Nanosuspension formulations for low-soluble drugs: pharmacokinetic evaluation using spironolactone as model compound, Drug Dev. Ind. Pharm. 31 (2005) 319-329. (Pubitemid 40463975)
-
(2005)
Drug Development and Industrial Pharmacy
, vol.31
, Issue.3
, pp. 319-329
-
-
Langguth, P.1
Hanafy, A.2
Frenzel, D.3
Grenier, P.4
Nhamias, A.5
Ohlig, T.6
Vergnault, G.7
Spahn-Langguth, H.8
-
60
-
-
61349191553
-
Enhancement of oral bioavailability of an HIV-attachment inhibitor by nanosizing and amorphous formulation approaches
-
M.G. Fakesa, Blisse J. Vakkalagaddab, Feng Qiana, Sridhar Desikana, Rajesh B. Gandhi, C. Lai, A. Hsieha, M.K. Franchini, H. Toaled, J. Brown, Enhancement of oral bioavailability of an HIV-attachment inhibitor by nanosizing and amorphous formulation approaches, Int. J. Pharm. 370 (2009) 167-174.
-
(2009)
Int. J. Pharm.
, vol.370
, pp. 167-174
-
-
Fakesa, M.G.1
Vakkalagaddab, B.J.2
Qiana, F.3
Desikana, S.4
Gandhi, R.B.5
Lai, C.6
Hsieha, A.7
Franchini, M.K.8
Toaled, H.9
Brown, J.10
-
61
-
-
79952922229
-
A formulation comparison between micro- And nanosuspensions: The importance of particle size for absorption of a model compound, following repeated oral administration to rats during early development
-
K. Sigfridsson, A. Nordmark, S. Theilig, A. Lindah, A formulation comparison between micro- and nanosuspensions: the importance of particle size for absorption of a model compound, following repeated oral administration to rats during early development, Drug Dev. Ind. Pharm. 37 (2011) 185-192.
-
(2011)
Drug Dev. Ind. Pharm.
, vol.37
, pp. 185-192
-
-
Sigfridsson, K.1
Nordmark, A.2
Theilig, S.3
Lindah, A.4
-
62
-
-
33344478634
-
Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs
-
DOI 10.1016/j.jconrel.2005.11.013, PII S0168365905006565
-
J. Jinno, N. Kamada, M. Miyake, K. Yamada, T. Mukai, M. Odomi, H. Toguchi, G.G. Liversidge, K. Higaki, T. Kimura, Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs, J. Control. Release 111 (2006) 56-64. (Pubitemid 43289995)
-
(2006)
Journal of Controlled Release
, vol.111
, Issue.1-2
, pp. 56-64
-
-
Jinno, J.-I.1
Kamada, N.2
Miyake, M.3
Yamada, K.4
Mukai, T.5
Odomi, M.6
Toguchi, H.7
Liversidge, G.G.8
Higaki, K.9
Kimura, T.10
-
63
-
-
20844446627
-
The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: A Beagle dog model predicts improved bioavailability and diminished food effect on absorption in human
-
DOI 10.1016/j.ijpharm.2004.08.001, PII S0378517304004831
-
Y. Wu, A. Loper, E. Landis, L. Hettrick, L. Novak, K. Lynn, C. Chen, K. Thompson, R. Higgins, U. Batra, S. Shelukar, G. Kwei, D. Storey, The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: a beagle dog model predicts improved bioavailability and diminished food effect on absorption in human, Int. J. Pharm. 285 (2004) 135-146. (Pubitemid 39361543)
-
(2004)
International Journal of Pharmaceutics
, vol.285
, Issue.1-2
, pp. 135-146
-
-
Wu, Y.1
Loper, A.2
Landis, E.3
Hettrick, L.4
Novak, L.5
Lynn, K.6
Chen, C.7
Thompson, K.8
Higgins, R.9
Batra, U.10
Shelukar, S.11
Kwei, G.12
Storey, D.13
-
64
-
-
33744973517
-
Oral bioavailability of cyclosporine: Solid lipid nanoparticles (SLN®) versus drug nanocrystals
-
DOI 10.1016/j.ijpharm.2006.02.045, PII S037851730600192X
-
R.H. Müller, S. Runge, V. Ravelli, W. Mehnert, A.F. Thünemann, E.B. Souto, Oral bioavailability of cyclosporine: solid lipid nanoparticles (SLN®) versus drug nanocrystals, Int. J. Pharm. 317 (2006) 82-89. (Pubitemid 43866342)
-
(2006)
International Journal of Pharmaceutics
, vol.317
, Issue.1
, pp. 82-89
-
-
Muller, R.H.1
Runge, S.2
Ravelli, V.3
Mehnert, W.4
Thunemann, A.F.5
Souto, E.B.6
-
65
-
-
0031402134
-
Mucoadhesion of colloidal particulate systems in the gastro-intestinal tract
-
DOI 10.1016/S0939-6411(97)00098-2, PII S0939641197000982
-
G. Ponchel, M.J. Montisci, A. Dembri, C. Durrer, D. Duchêne, Mucoadhesion of colloidal particulate systems in the gastro-intestinal tract, Eur. J. Pharm. Biopharm. 44 (1997) 25-31. (Pubitemid 28298772)
-
(1997)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.44
, Issue.1
, pp. 25-31
-
-
Ponchel, G.1
Montisci, M.-J.2
Dembri, A.3
Durrer, C.4
Duchene, D.5
-
66
-
-
0345267135
-
Bioadhesion of solid oral dosage forms, why and how?
-
DOI 10.1016/S0939-6411(97)00097-0, PII S0939641197000970
-
D. Duchêne, G. Ponchel, Bioadhesion of solid oral dosage forms, why and how? Eur. J. Pharm. Biopharm. 44 (1997) 15-23. (Pubitemid 28298771)
-
(1997)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.44
, Issue.1
, pp. 15-23
-
-
Duchene, D.1
Ponchel, G.2
-
67
-
-
17444372009
-
Mucoadhesives in the gastrointestinal tract: Revisiting the literature for novel applications
-
DOI 10.1016/j.ejpb.2005.01.007
-
D. Dodou, P. Breedveld, P.A. Wieringa, Mucoadhesives in the gastrointestinal tract: revisiting the literature for novel applications, Eur. J. Pharm. Biopharm. 60 (2005) 1-16. (Pubitemid 40545855)
-
(2005)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.60
, Issue.1
, pp. 1-16
-
-
Dodou, D.1
Breedveld, P.2
Wieringa, P.A.3
-
68
-
-
26644454810
-
The basics and underlying mechanisms of mucoadhesion
-
DOI 10.1016/j.addr.2005.07.001, PII S0169409X05001390, Mucoadhesive Polymers: Strategies, Achievements and Future Challenges
-
J.D. Smart, The basics and underlying mechanisms of mucoadhesion, Adv. Drug Deliv. Rev. 57 (2005) 1556-1568. (Pubitemid 41443469)
-
(2005)
Advanced Drug Delivery Reviews
, vol.57
, Issue.11
, pp. 1556-1568
-
-
Smart, J.D.1
-
69
-
-
0035910888
-
A new approach for targeting to Cryptosporidium parvum using mucoadhesive nanosuspensions: Research and applications
-
DOI 10.1016/S0378-5173(00)00640-2, PII S0378517300006402
-
O. Kayser, A newapproach for targeting to Cryptosporidiumparvum usingmucoadhesive nanosuspensions: research and applications, Int. J. Pharm. 214 (2001) 83-85. (Pubitemid 32244083)
-
(2001)
International Journal of Pharmaceutics
, vol.214
, Issue.1-2
, pp. 83-85
-
-
Kayser, O.1
-
70
-
-
33751253462
-
Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
-
DOI 10.1016/j.jconrel.2006.08.013, PII S0168365906004020
-
A. des Rieux, V. Fievez, M. Garinot, Y.J. Schneider, V. Préat, Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach, J. Control. Release 116 (2006) 1-27. (Pubitemid 44792295)
-
(2006)
Journal of Controlled Release
, vol.116
, Issue.1
, pp. 1-27
-
-
Des, R.A.1
Fievez, V.2
Garinot, M.3
Schneider, Y.-J.4
Preat, V.5
-
71
-
-
33748885473
-
Low molecular weight heparin nanoparticles: Mucoadhesion and behaviour in Caco-2 cells
-
DOI 10.1088/0957-4484/17/15/009, PII S0957448406226916, 009
-
A. Lamprecht, P. Koenig, N. Ubrich, P. Maincent, D. Neumann, Low molecular weight heparin nanoparticles: mucoadhesion and behaviour in Caco-2 cells, Nanotechnology 17 (2006) 3673-3680. (Pubitemid 44424393)
-
(2006)
Nanotechnology
, vol.17
, Issue.15
, pp. 3673-3680
-
-
Lamprecht, A.1
Koenig, P.2
Ubrich, N.3
Maincent, P.4
Neumann, D.5
-
72
-
-
0032402219
-
Evaluation of nano- and microparticle uptake by the gastrointestinal tract
-
DOI 10.1016/S0169-409X(98)00041-6, PII S0169409X98000416
-
F. Delie, Evaluation of nano- and microparticle uptake by the gastrointestinal tract, Adv. Drug Deliv. Rev. 34 (1998) 221-233. (Pubitemid 28535113)
-
(1998)
Advanced Drug Delivery Reviews
, vol.34
, Issue.2-3
, pp. 221-233
-
-
Delie, F.1
-
74
-
-
0030471901
-
Gastrointestinal uptake of biodegradable microparticles: Effect of particle size
-
DOI 10.1023/A:1016085108889
-
M.P. Desai, V. Labhasetwar, G.L. Amidon, R.J. Levy Gastrointestinal, Uptake of biodegradable microparticles: effect of particle size, Pharm. Res. 13 (1996) 1838-1845. (Pubitemid 27034116)
-
(1996)
Pharmaceutical Research
, vol.13
, Issue.12
, pp. 1838-1845
-
-
Desai, M.P.1
Labhasetwar, V.2
Amidon, G.L.3
Levy, R.J.4
-
75
-
-
33751253462
-
Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
-
DOI 10.1016/j.jconrel.2006.08.013, PII S0168365906004020
-
A. des Rieux, V. Fievez, M. Garinot, Y.J. Scheider, V. Preat, Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach, J. Control. Release 116 (2006) 1-27. (Pubitemid 44792295)
-
(2006)
Journal of Controlled Release
, vol.116
, Issue.1
, pp. 1-27
-
-
Des, R.A.1
Fievez, V.2
Garinot, M.3
Schneider, Y.-J.4
Preat, V.5
-
76
-
-
0032714228
-
Inhibition of P-glycoprotein by D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS)
-
DOI 10.1023/A:1015000503629
-
J.M. Dintaman, J.A. Silverman, Inhibition of P-glycoprotein by D-alphatocopheryl polyethylene glycol 1000 succinate (TPGS), Pharm. Res. 16 (1999) 1550-1556. (Pubitemid 29510551)
-
(1999)
Pharmaceutical Research
, vol.16
, Issue.10
, pp. 1550-1556
-
-
Dintaman, J.M.1
Silverman, J.A.2
-
77
-
-
77953359223
-
The effects of excipients on transporter mediated absorption
-
J. Goole, D.J. Lindley, W. Roth, S.M. Carl, K. Amighi, J.M. Kauffmann, G.T. Knipp, The effects of excipients on transporter mediated absorption, Int. J. Pharm. 393 (2010) 17-31.
-
(2010)
Int. J. Pharm.
, vol.393
, pp. 17-31
-
-
Goole, J.1
Lindley, D.J.2
Roth, W.3
Carl, S.M.4
Amighi, K.5
Kauffmann, J.M.6
Knipp, G.T.7
-
78
-
-
42649107490
-
Effect of pluronic F68 block copolymer on P-glycoprotein transport and CYP3A4 metabolism
-
J. Huang, L. Si, L. Jiang, Z. Fan, J. Qiu, G. Li, Effect of pluronic F68 block copolymer on P-glycoprotein transport and CYP3A4 metabolism, Int. J. Pharm. 356 (2008) 351-353.
-
(2008)
Int. J. Pharm.
, vol.356
, pp. 351-353
-
-
Huang, J.1
Si, L.2
Jiang, L.3
Fan, Z.4
Qiu, J.5
Li, G.6
-
79
-
-
61449188212
-
Inhibiting efflux with novel non-ionic surfactants: Rational design based on vitamin e TPGS
-
M.F. Wempe, C. Wright, J.L. Little, J.W. Lightner, S.E. Large, G.B. Caflisch, C.M. Buchanan, P.J. Rice, V.J. Wacher, K.M. Ruble, K.J. Edgar, Inhibiting efflux with novel non-ionic surfactants: rational design based on vitamin E TPGS, Int. J. Pharm. 370 (2009) 93-102.
-
(2009)
Int. J. Pharm.
, vol.370
, pp. 93-102
-
-
Wempe, M.F.1
Wright, C.2
Little, J.L.3
Lightner, J.W.4
Large, S.E.5
Caflisch, G.B.6
Buchanan, C.M.7
Rice, P.J.8
Wacher, V.J.9
Ruble, K.M.10
Edgar, K.J.11
-
80
-
-
0033496577
-
Relative bioavailability and effects of a high fat meal on single dose cilostazol pharmacokinetics
-
S.L. Bramer,W.P. Forbes, Relative bioavailability and effects of a high fatmeal on single dose cilostazol pharmacokinetics, Clin. Pharmacokinet. 37 (Suppl. 2) (1999) 13-23. (Pubitemid 30171183)
-
(1999)
Clinical Pharmacokinetics
, vol.37
, Issue.SUPPL. 2
, pp. 13-23
-
-
Bramer, S.L.1
Forbes, W.P.2
-
81
-
-
32544458008
-
Absence of a food effect with a 145 mg nanoparticle fenofibrate tablet formulation
-
A. Hanafy, H. Spahn-Langguth, G. Vergnault, P. Grenier, M. Tubic Grozdanis, T. Lenhardt, P. Langguth, Absence of a food effect with a 145 mg nanoparticle fenofibrate tablet formulation, Int. J. Clin. Pharmacol. Ther. 44 (2006) 64-70.
-
(2006)
Int. J. Clin. Pharmacol. Ther.
, vol.44
, pp. 64-70
-
-
Hanafy, A.1
Spahn-Langguth, H.2
Vergnault, G.3
Grenier, P.4
Tubic Grozdanis, M.5
Lenhardt, T.6
Langguth, P.7
-
82
-
-
51649091116
-
Conversion of nanosuspensions into dry powders by spray drying: A case study
-
M.V. Chaubal, C. Popescu, Conversion of nanosuspensions into dry powders by spray drying: a case study, Pharm. Res. 25 (2008) 2302-2308.
-
(2008)
Pharm. Res.
, vol.25
, pp. 2302-2308
-
-
Chaubal, M.V.1
Popescu, C.2
-
83
-
-
80053980485
-
Nanocrystals as tool to improve piroxicam dissolution rate in novel orally disintegrating tablets
-
F. Lai, E. Pini, G. Angioni, M.L. Manca, J. Perricci, C. Sinico, A.M. Fadda, Nanocrystals as tool to improve piroxicam dissolution rate in novel orally disintegrating tablets, Eur. J. Pharm. Biopharm. 79 (2011) 552-558.
-
(2011)
Eur. J. Pharm. Biopharm.
, vol.79
, pp. 552-558
-
-
Lai, F.1
Pini, E.2
Angioni, G.3
Manca, M.L.4
Perricci, J.5
Sinico, C.6
Fadda, A.M.7
-
84
-
-
79958005215
-
Potent dried drug nanosuspensions for oral bioavailability enhancement of poorly soluble drugs with pH-dependent solubility
-
D. Mou, H. Chen, J. Wan, H. Xu, X. Yang, Potent dried drug nanosuspensions for oral bioavailability enhancement of poorly soluble drugs with pH-dependent solubility, Int. J. Pharm. 413 (2011) 237-244.
-
(2011)
Int. J. Pharm.
, vol.413
, pp. 237-244
-
-
Mou, D.1
Chen, H.2
Wan, J.3
Xu, H.4
Yang, X.5
-
85
-
-
38749119045
-
Effect of arginine hydrochloride and hydroxypropyl cellulose as stabilizers on the physical stability of high drug loading nanosuspensions of a poorly soluble compound
-
DOI 10.1016/j.ijpharm.2007.09.029, PII S0378517307008204
-
A. Ain-Ai, P.K. Gupta, Effect of arginine hydrochloride and hydroxypropyl cellulose as stabilizers on the physical stability of high drug loading nanosuspensions of a poorly soluble compound, Int. J. Pharm. 351 (2008) 282-288. (Pubitemid 351186858)
-
(2008)
International Journal of Pharmaceutics
, vol.351
, Issue.1-2
, pp. 282-288
-
-
Ain-Ai, A.1
Gupta, P.K.2
-
86
-
-
33745617678
-
Surface functionalized alumina nanoparticle filled polymeric nanocomposites with enhanced mechanical properties
-
DOI 10.1039/b603020c
-
Z. Guo, T. Pereira, O. Choi, Y. Wang, H.T. Hahn, Surface functionalized alumina nanoparticle filled polymeric nanocomposites with enhanced mechanical properties, J. Mater. Chem. 16 (2006) 2800-2808. (Pubitemid 43993797)
-
(2006)
Journal of Materials Chemistry
, vol.16
, Issue.27
, pp. 2800-2808
-
-
Guo, Z.1
Pereira, T.2
Choi, O.3
Wang, Y.4
Hahn, H.T.5
-
87
-
-
60049090585
-
Design of biodegradable nanoparticles for oral delivery of doxorubicin: In vivo pharmacokinetics and toxicity studies in rats
-
D.R. Kalaria, G. Sharma, V. Beniwal, M.N. Ravi Kumar, Design of biodegradable nanoparticles for oral delivery of doxorubicin: in vivo pharmacokinetics and toxicity studies in rats, Pharm. Res. 26 (2009) 492-501.
-
(2009)
Pharm. Res.
, vol.26
, pp. 492-501
-
-
Kalaria, D.R.1
Sharma, G.2
Beniwal, V.3
Ravi Kumar, M.N.4
-
88
-
-
5344234787
-
The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs
-
DOI 10.1016/j.ijpharm.2004.07.019, PII S0378517304004582
-
J.E. Kipp, The role of solid nanoparticle technology in parenteral delivery of poorly water soluble drugs, Int. J. Pharm. 284 (2004) 109-122. (Pubitemid 39349144)
-
(2004)
International Journal of Pharmaceutics
, vol.284
, Issue.1-2
, pp. 109-122
-
-
Kipp, J.E.1
-
89
-
-
78650531221
-
SDS-coated atovaquone nanosuspensions show improved therapeutic efficacy against experimental acquired and reactivated toxoplasmosis by improving passage of gastrointestinal and blood-brain barriers
-
H.M. Shubar, S. Lachenmaier, M.M. Heimesaat, U. Lohman, R. Mauludin, R.H. Müller, R. Fitzner, K. Borner, O. Liesenfeld, SDS-coated atovaquone nanosuspensions show improved therapeutic efficacy against experimental acquired and reactivated toxoplasmosis by improving passage of gastrointestinal and blood-brain barriers, J. Drug Target. 19 (2011) 114-124.
-
(2011)
J. Drug Target.
, vol.19
, pp. 114-124
-
-
Shubar, H.M.1
Lachenmaier, S.2
Heimesaat, M.M.3
Lohman, U.4
Mauludin, R.5
Müller, R.H.6
Fitzner, R.7
Borner, K.8
Liesenfeld, O.9
-
90
-
-
78649648146
-
Pharmaceutical nanocrystals by nanomilling: Critical process parameters, particle fracturing and stabilization method
-
L. Peltonen, J. Hirvonen, Pharmaceutical nanocrystals by nanomilling: critical process parameters, particle fracturing and stabilization method, J. Pharm. Pharmacol. 62 (2010) 1569-1579.
-
(2010)
J. Pharm. Pharmacol.
, vol.62
, pp. 1569-1579
-
-
Peltonen, L.1
Hirvonen, J.2
-
91
-
-
67349098845
-
Diclofenac nanosuspensions: Influence of preparation procedure and crystal form on drug dissolution behavior
-
F. Lai, C. Sinico, G. Ennas, F. Marongiu, G. Marongiu, A.M. Fadda, Diclofenac nanosuspensions: influence of preparation procedure and crystal form on drug dissolution behavior, Int. J. Pharm. 373 (2009) 124-132.
-
(2009)
Int. J. Pharm.
, vol.373
, pp. 124-132
-
-
Lai, F.1
Sinico, C.2
Ennas, G.3
Marongiu, F.4
Marongiu, G.5
Fadda, A.M.6
-
92
-
-
0033805179
-
In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs
-
J.B. Dressman, C. Reppas, In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs, Eur. J. Pharm. Sci. 11 (Suppl. 2) (2000) S73-S80.
-
(2000)
Eur. J. Pharm. Sci.
, vol.11
, Issue.SUPPL. 2
-
-
Dressman, J.B.1
Reppas, C.2
-
93
-
-
4544275025
-
Challenges and solutions for the delivery of biotech drugs - A review of drug nanocrystal technology and lipid nanoparticles
-
DOI 10.1016/j.jbiotec.2004.06.007, PII S0168165604003128
-
R.H. Muller, C.M. Keck, Challenges and solutions for the delivery of biotech drugs - a review of drug nanocrystal technology and lipid nanoparticles, J. Biotechnol. 113 (2004) 151-170. (Pubitemid 39237077)
-
(2004)
Journal of Biotechnology
, vol.113
, Issue.1-3
, pp. 151-170
-
-
Muller, R.H.1
Keck, C.M.2
-
94
-
-
34547259640
-
Pharmacokinetic evaluation of a 1,3-dicyclohexylurea nanosuspension formulation to support early efficacy assessment
-
DOI 10.1007/s11671-007-9063-7
-
J.L. Wahlstrom, P. Chiang, S. Ghosh, C.J. Warren, S.P. Wene, L.A. Albin, M.E. Smith, S.L. Roberds, Pharmacokinetic evaluation of a 1,3-dicyclohexylurea nanosuspension formulation to support early efficacy assessment, Nanoscale Res. Lett. 2 (2007) 291-296. (Pubitemid 47139334)
-
(2007)
Nanoscale Research Letters
, vol.2
, Issue.6
, pp. 291-296
-
-
Wahlstrom, J.L.1
Chiang, P.-C.2
Ghosh, S.3
Warren, C.J.4
Wene, S.P.5
Albin, L.A.6
Smith, M.E.7
Roberds, S.L.8
-
95
-
-
77956398535
-
Preparation, characterization, pharmacokinetics, and tissue distribution of curcumin nanosuspension with TPGS as stabilizer
-
Y. Gao, Z. Li,M. Sun,H. Li, C.Guo, J. Cui, A. Li, F. Cao, Y. Xi, H. Lou, G. Zhai, Preparation, characterization, pharmacokinetics, and tissue distribution of curcumin nanosuspension with TPGS as stabilizer, Drug Dev. Ind. Pharm. 36 (2010) 1225-1234.
-
(2010)
Drug Dev. Ind. Pharm.
, vol.36
, pp. 1225-1234
-
-
Gao, Y.1
Li, Z.2
Sun, M.3
Li, H.4
Guo, C.5
Cui, J.6
Li, A.7
Cao, F.8
Xi, Y.9
Lou, H.10
Zhai, G.11
-
96
-
-
0006014154
-
Tissue distribution and plasma clearance of a novel microcrystalline- coated flurbiprofen formulation
-
M. Clement, W. Pugh, I. Parikh, Tissue distribution and plasma clearance of a novel microcrystalline-coated flurbiprofen formulation, Pharmacologist 34 (1992) 204-211.
-
(1992)
Pharmacologist
, vol.34
, pp. 204-211
-
-
Clement, M.1
Pugh, W.2
Parikh, I.3
-
97
-
-
67349084376
-
Polymeric nanoparticulate system: A potential approach for ocular drug delivery
-
R.C. Nagarwal, S. Kant, P.N. Singh, P. Maiti, J.K. Pandit, Polymeric nanoparticulate system: a potential approach for ocular drug delivery, J. Control. Release 136 (2009) 2-13.
-
(2009)
J. Control. Release
, vol.136
, pp. 2-13
-
-
Nagarwal, R.C.1
Kant, S.2
Singh, P.N.3
Maiti, P.4
Pandit, J.K.5
-
98
-
-
77949917853
-
Sparfloxacin loaded PLGA nanoparticles for sustained ocular drug delivery
-
H. Gupta, M. Aqil, R.K. Khar, A. Ali, A. Bhatnagar, G. Mittal, Sparfloxacin loaded PLGA nanoparticles for sustained ocular drug delivery, Nanomedicine 6 (2010) 324-333.
-
(2010)
Nanomedicine
, vol.6
, pp. 324-333
-
-
Gupta, H.1
Aqil, M.2
Khar, R.K.3
Ali, A.4
Bhatnagar, A.5
Mittal, G.6
-
99
-
-
78651356705
-
Hydrocortisone nanosuspensions for ophthalmic delivery: A comparative study between microfluidic nanoprecipitation and media milling
-
H.S. Ali, P. York, A.M. Ali, N. Blagden, Hydrocortisone nanosuspensions for ophthalmic delivery: a comparative study between microfluidic nanoprecipitation and media milling, J. Control. Release 149 (2011) 175-181.
-
(2011)
J. Control. Release
, vol.149
, pp. 175-181
-
-
Ali, H.S.1
York, P.2
Ali, A.M.3
Blagden, N.4
-
101
-
-
13844297094
-
The impact of nanobiotechnology on the development of new drug delivery systems
-
O. Kayser, A. Lemke, N. Hernández-Trejo, The impact of nanobiotechnology on the development of newdrug delivery systems, Curr. Pharm. Biotechnol. 6 (2005) 3-5. (Pubitemid 40246748)
-
(2005)
Current Pharmaceutical Biotechnology
, vol.6
, Issue.1
, pp. 3-5
-
-
Kayser, O.1
Lemke, A.2
Hernandez-Trejo, N.3
-
102
-
-
0035999781
-
Flurbiprofen-loaded acrylate polymer nanosuspensions for ophthalmic application
-
DOI 10.1016/S0142-9612(02)00080-7, PII S0142961202000807
-
R. Pignatello, C. Bucolo, G. Spedalieri, A. Maltese, G. Puglisi, Flurbiprofen-loaded acrylate polymer nanosuspensions for ophthalmic application, Biomaterials 23 (2002) 3247-3255. (Pubitemid 34522137)
-
(2002)
Biomaterials
, vol.23
, Issue.15
, pp. 3247-3255
-
-
Pignatello, R.1
Bucolo, C.2
Spedalieri, G.3
Maltese, A.4
Puglisi, G.5
-
103
-
-
77957998482
-
Nanoparticles in drug delivery: Potential green nanobiomedicine applications
-
R. Ravichandran, Nanoparticles in drug delivery: potential green nanobiomedicine applications, Int. J. Green Nanotechnol. Biomed. 1 (2009) B108-B130.
-
(2009)
Int. J. Green Nanotechnol. Biomed.
, vol.1
-
-
Ravichandran, R.1
-
104
-
-
77955052417
-
Miconazole nanosuspensions: Influence of formulation variables on particle size reduction and physical stability
-
A.M. Cerdeira, M. Mazzotti, B. Gander, Miconazole nanosuspensions: influence of formulation variables on particle size reduction and physical stability, Int. J. Pharm. 396 (2010) 210-218.
-
(2010)
Int. J. Pharm.
, vol.396
, pp. 210-218
-
-
Cerdeira, A.M.1
Mazzotti, M.2
Gander, B.3
-
105
-
-
34447254990
-
Nanosuspension as an ophthalmic delivery system for certain glucocorticoid drugs
-
DOI 10.1016/j.ijpharm.2007.03.011, PII S037851730700244X
-
M.A. Kassem, A.A. Abdel Rahman, M.M. Ghorab, M.B. Ahmed, R.M. Khalil, Nanosuspension as an ophthalmic delivery system for certain glucocorticoid drugs, Int. J. Pharm. 340 (2007) 126-133. (Pubitemid 47043351)
-
(2007)
International Journal of Pharmaceutics
, vol.340
, Issue.1-2
, pp. 126-133
-
-
Kassem, M.A.1
Abdel, R.A.A.2
Ghorab, M.M.3
Ahmed, M.B.4
Khalil, R.M.5
-
106
-
-
59949091288
-
Evaluation of aerosol delivery of nanosuspension for pre-clinical pulmonary drug delivery
-
P. Chiang, J.W. Alsup, Y. Lai, Y. Hu, B.R. Heyde, D. Tung, Evaluation of aerosol delivery of nanosuspension for pre-clinical pulmonary drug delivery, Nanoscale Res. Lett. 4 (2009) 254-261.
-
(2009)
Nanoscale Res. Lett.
, vol.4
, pp. 254-261
-
-
Chiang, P.1
Alsup, J.W.2
Lai, Y.3
Hu, Y.4
Heyde, B.R.5
Tung, D.6
-
108
-
-
79957692320
-
Formation, characterization, and fate of inhaled drug nanoparticles
-
J. Zhang, L. Wu, H. Chan, W. Watanabe, Formation, characterization, and fate of inhaled drug nanoparticles, Adv. Drug Deliv. Rev. 63 (2011) 441-455.
-
(2011)
Adv. Drug Deliv. Rev.
, vol.63
, pp. 441-455
-
-
Zhang, J.1
Wu, L.2
Chan, H.3
Watanabe, W.4
-
110
-
-
0344513087
-
Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications
-
DOI 10.1046/j.1365-2125.2003.01892.x
-
N.R. Labiris, M.B. Dolovich, Pulmonary drug delivery. Part I: physiological factors affecting therapeutic effectiveness of aerosolized medications, Br. J. Clin. Pharmacol. 56 (2003) 588-599. (Pubitemid 37491710)
-
(2003)
British Journal of Clinical Pharmacology
, vol.56
, Issue.6
, pp. 588-599
-
-
Labiris, N.R.1
Dolovich, M.B.2
-
111
-
-
33845906339
-
Inhaling medicines: Delivering drugs to the body through the lungs
-
DOI 10.1038/nrd2153, PII NRD2153
-
J.S. Patton, P.R. Byron, Inhaling medicines: delivering drugs to the body through the lungs, Nat. Rev. Drug Discov. 6 (2007) 67-74. (Pubitemid 46020287)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.1
, pp. 67-74
-
-
Patton, J.S.1
Byron, P.R.2
-
113
-
-
47949098294
-
High bioavailability from nebulized itraconazole nanoparticle dispersions with biocompatible stabilizers
-
W. Yang, J. Tam, D.A. Miller, J. Zhou, J.T. McConville, K.P. Johnstonb, R.O. Williams III, High bioavailability from nebulized itraconazole nanoparticle dispersions with biocompatible stabilizers, Int. J. Pharm. 361 (2008) 177-188.
-
(2008)
Int. J. Pharm.
, vol.361
, pp. 177-188
-
-
Yang, W.1
Tam, J.2
Miller, D.A.3
Zhou, J.4
McConville, J.T.5
Johnstonb, K.P.6
Williams III, R.O.7
-
114
-
-
42649106878
-
Nanoparticles: Characteristics, mechanisms of action, and toxicity in pulmonary drug delivery - A review
-
DOI 10.1166/jbn.2007.015
-
S. Gill, R. Lobenberg, T. Ku, S. Azarmi, W. Roa, E.J. Prenner, Nanoparticles: characteristics, mechanisms of action, and toxicity in pulmonary drug delivery-a review, J. Biomed. Nanotechnol. 3 (2007) 107-119. (Pubitemid 351877160)
-
(2007)
Journal of Biomedical Nanotechnology
, vol.3
, Issue.2
, pp. 107-119
-
-
Gill, S.1
Lobenberg, R.2
Ku, T.3
Azarmi, S.4
Roa, W.5
Prenner, E.J.6
-
115
-
-
0033495184
-
Pharmacodynamics and pharmacokinetics of budesonide: A new nebulized corticosteroid
-
S.J. Szefler, Pharmacodynamics and pharmacokinetics of budesonide: a new nebulized corticosteroid, J. Allergy Clin. Immunol. 104 (1999) S175-S183. (Pubitemid 30246942)
-
(1999)
Journal of Allergy and Clinical Immunology
, vol.104
, Issue.4 II
-
-
Szefler, S.J.1
-
116
-
-
77951652999
-
Comparison of bioavailability of amorphous versus crystalline itraconazole nanoparticles via pulmonary administration in rats
-
W. Yang, K.P. Johnston, R.O. Williams III, Comparison of bioavailability of amorphous versus crystalline itraconazole nanoparticles via pulmonary administration in rats, Eur. J. Pharm. Biopharm. 75 (2010) 33-41.
-
(2010)
Eur. J. Pharm. Biopharm.
, vol.75
, pp. 33-41
-
-
Yang, W.1
Johnston, K.P.2
Williams III, R.O.3
-
117
-
-
59849083500
-
Development and clinical trial of nano-atropine sulfate dry powder inhaler as a novel organophosphorous poisoning antidote
-
R. Ali, G.K. Jain, Z. Iqbal, S. Talegaonkar, P. Pandit, S. Sule, G. Malhotra, R.K. Khar, A. Bhatnagar, F.J. Ahmad, Development and clinical trial of nano-atropine sulfate dry powder inhaler as a novel organophosphorous poisoning antidote, Nanomedicine 5 (2009) 55-63.
-
(2009)
Nanomedicine
, vol.5
, pp. 55-63
-
-
Ali, R.1
Jain, G.K.2
Iqbal, Z.3
Talegaonkar, S.4
Pandit, P.5
Sule, S.6
Malhotra, G.7
Khar, R.K.8
Bhatnagar, A.9
Ahmad, F.J.10
-
118
-
-
0037378033
-
In vivo pharmacodynamics of antifungal drugs in treatment of candidiasis
-
DOI 10.1128/AAC.47.4.1179-1186.2003
-
D. Andes, Minireview: in vivo pharmacodynamics of antifungal drugs in treatment of candidiasis, Antimicrob. Agents Chemother. 47 (2003) 1179-1186. (Pubitemid 36368572)
-
(2003)
Antimicrobial Agents and Chemotherapy
, vol.47
, Issue.4
, pp. 1179-1186
-
-
Andes, D.1
-
119
-
-
0347361711
-
Pharmacodynamics of a New Triazole, Posaconazole, in a Murine Model of Disseminated Candidiasis
-
DOI 10.1128/AAC.48.1.137-142.2004
-
D. Andes, K. Marchillo, R. Conklin, G. Krishna, F. Ezzet, A. Cacciapuoti, D. Loebenberg, Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis, Antimicrob. Agents Chemother. 48 (2004) 137-142. (Pubitemid 38040189)
-
(2004)
Antimicrobial Agents and Chemotherapy
, vol.48
, Issue.1
, pp. 137-142
-
-
Andes, D.1
Marchillo, K.2
Conklin, R.3
Krishna, G.4
Ezzet, F.5
Cacciapuoti, A.6
Loebenberg, D.7
-
120
-
-
0037453179
-
Formulation of amphotericin B as nanosuspension for oral administration
-
DOI 10.1016/S0378-5173(02)00686-5
-
O. Kayser, C. Olbrich, V. Yardley, A.F. Kiderlen, S.L. Croft, Formulation of amphotericin B as nanosuspension for oral administration, Int. J. Pharm. 254 (2003) 73-75. (Pubitemid 36259814)
-
(2003)
International Journal of Pharmaceutics
, vol.254
, Issue.1
, pp. 73-75
-
-
Kayser, O.1
Olbrich, C.2
Yardley, V.3
Kiderlen, A.F.4
Croft, S.L.5
-
121
-
-
8444227803
-
Uptake of folate-conjugated albumin nanoparticles to the SKOV3 cells
-
DOI 10.1016/j.ijpharm.2004.08.015, PII S0378517304004934
-
L. Zhang, S. Hou, S. Mao, D. Wei, X. Song, Y. Lu, Uptake of folate-conjugated albumin nanoparticles to the SKOV3 cells, Int. J. Pharm. 287 (2004) 155-162. (Pubitemid 39487253)
-
(2004)
International Journal of Pharmaceutics
, vol.287
, Issue.1-2
, pp. 155-162
-
-
Zhang, L.1
Hou, S.2
Mao, S.3
Wei, D.4
Song, X.5
Lu, Y.6
-
122
-
-
0343882023
-
Targeted drug delivery via the folate receptor
-
DOI 10.1016/S0169-409X(99)00062-9, PII S0169409X99000629
-
J. Sudimack, R.J. Lee, Targeted drug delivery via folate receptor, Adv. Drug Deliv. Rev. 41 (2000) 147-162. (Pubitemid 30122955)
-
(2000)
Advanced Drug Delivery Reviews
, vol.41
, Issue.2
, pp. 147-162
-
-
Sudimack, J.1
Lee, R.J.2
-
123
-
-
84855845750
-
Polymeric carrier systems for siRNA delivery
-
P. Vader, L.J. van der Aa, G. Storm, R.M. Schiffelers, J.F. Engbersen, Polymeric carrier systems for siRNA delivery, Curr. Top. Med. Chem. 12 (2012) 108-119.
-
(2012)
Curr. Top. Med. Chem.
, vol.12
, pp. 108-119
-
-
Vader, P.1
Van Der Aa, L.J.2
Storm, G.3
Schiffelers, R.M.4
Engbersen, J.F.5
-
124
-
-
79957794004
-
Cancer cell invasion: Treatment and monitoring opportunities in nanomedicine
-
O. Veiseh, F.M. Kievit, R.G. Ellenbogen, M. Zhang, Cancer cell invasion: treatment and monitoring opportunities in nanomedicine, Adv. Drug Deliv. Rev. 63 (2011) 582-596.
-
(2011)
Adv. Drug Deliv. Rev.
, vol.63
, pp. 582-596
-
-
Veiseh, O.1
Kievit, F.M.2
Ellenbogen, R.G.3
Zhang, M.4
-
125
-
-
0030853702
-
Influence of the type of surfactant on the analgesic effects induced by the peptide dalargin after its delivery across the blood-brain barrier using surfactant-coated nanoparticles
-
DOI 10.1016/S0168-3659(97)00061-8, PII S0168365997000618
-
J. Kreuter, V.E. Petrov, D.A. Kharkevich, R.N. Alyautdin, Influence of the type of surfactant on the analgesic effects induced by the peptide dalargin after its delivery across the blood-brain barrier using surfactant-coated nanoparticles, J. Control. Release 49 (1997) 81-87. (Pubitemid 27417903)
-
(1997)
Journal of Controlled Release
, vol.49
, Issue.1
, pp. 81-87
-
-
Kreuter, J.1
Petrov, V.E.2
Kharkevich, D.A.3
Alyautdin, R.N.4
-
126
-
-
39449117736
-
Injectable actarit-loaded solid lipid nanoparticles as passive targeting therapeutic agents for rheumatoid arthritis
-
DOI 10.1016/j.ijpharm.2007.10.014, PII S0378517307008435
-
J. Ye, Q. Wang, X. Zhou, N. Zhang, Injectable actarit-loaded solid lipid nanoparticles as passive targeting therapeutic agents for rheumatoid arthritis, Int. J. Pharm. 352 (2008) 273-279. (Pubitemid 351273921)
-
(2008)
International Journal of Pharmaceutics
, vol.352
, Issue.1-2
, pp. 273-279
-
-
Ye, J.1
Wang, Q.2
Zhou, X.3
Zhang, N.4
-
127
-
-
14644396096
-
Nanomedicine: Current status and future prospects
-
DOI 10.1096/fj.04-2747rev
-
S.M. Moghimi, A.C. Hunter, J.C. Murray, Nanomedicine: current status and future prospects, FASEB J. 19 (2005) 311-330. (Pubitemid 40316520)
-
(2005)
FASEB Journal
, vol.19
, Issue.3
, pp. 311-330
-
-
Moghimi, S.M.1
Hunter, A.C.2
Murray, J.C.3
-
128
-
-
76749169348
-
To PEGylate or not PEGylate, that is not the question
-
K. Park, To PEGylate or not PEGylate, that is not the question, J. Control. Release 142 (2010) 147-148.
-
(2010)
J. Control. Release
, vol.142
, pp. 147-148
-
-
Park, K.1
-
129
-
-
70350436076
-
Stealth nanoparticles coated with heparin as peptide or peptide carriers
-
M. Socha, P. Bartecki, C. Passitani, A. Sapin, C. Damge, T. Lecompte, J. Barre, E. Ghazouani, P. Maincent, Stealth nanoparticles coated with heparin as peptide or peptide carriers, J. Drug Target. 17 (2009) 575-585.
-
(2009)
J. Drug Target.
, vol.17
, pp. 575-585
-
-
Socha, M.1
Bartecki, P.2
Passitani, C.3
Sapin, A.4
Damge, C.5
Lecompte, T.6
Barre, J.7
Ghazouani, E.8
Maincent, P.9
-
130
-
-
29244441966
-
Poly(ethylene oxide)-modified poly(β-amino ester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs: Part 2. In vivo distribution and tumor localization studies
-
DOI 10.1007/s11095-005-8343-0
-
D. Shenoy, S. Little, R. Langer, M. Amiji, Poly(ethylene oxide)-modified poly(- beta-amino ester) nanoparticles as a pH-sensitive system for tumor targeted delivery of hydrophobic drugs: part 2. In vivo distribution and tumor localization studies, Pharm. Res. 22 (2005) 2107-2114. (Pubitemid 41821590)
-
(2005)
Pharmaceutical Research
, vol.22
, Issue.12
, pp. 2107-2114
-
-
Shenoy, D.1
Little, S.2
Langer, R.3
Amiji, M.4
-
131
-
-
81755174204
-
Surface modified nevirapine nanosuspensions for viral reservoir targeting: In vitro and in vivo evaluation
-
R. Shegokara, K.K. Singha, Surface modified nevirapine nanosuspensions for viral reservoir targeting: in vitro and in vivo evaluation, Int. J. Pharm. 421 (2011) 341-352.
-
(2011)
Int. J. Pharm.
, vol.421
, pp. 341-352
-
-
Shegokara, R.1
Singha, K.K.2
-
132
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Y. Matsumura, H. Maeda, A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS, Cancer Res. 46 (1986) 6387-6392. (Pubitemid 17221789)
-
(1986)
Cancer Research
, vol.46
, Issue.12 I
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
133
-
-
79960153105
-
Preparation and antitumor study of camptothecin nanocrystals
-
H. Zhang, C.P. Hollis, Q. Zhang, T. Li, Preparation and antitumor study of camptothecin nanocrystals, Int. J. Pharm. 415 (2011) 293-300.
-
(2011)
Int. J. Pharm.
, vol.415
, pp. 293-300
-
-
Zhang, H.1
Hollis, C.P.2
Zhang, Q.3
Li, T.4
-
134
-
-
79960422870
-
Oridonin nanosuspension enhances anti-tumor efficacy in SMMC-7721 cells and H22 tumor bearing mice
-
H. Lou, L. Gao, X. Wei, Z. Zhang, D. Zheng, D. Zhang, X. Zhang, Y. Li, Q. Zhang, Oridonin nanosuspension enhances anti-tumor efficacy in SMMC-7721 cells and H22 tumor bearing mice, Colloids Surf. B Biointerfaces 87 (2011) 319-325.
-
(2011)
Colloids Surf. B Biointerfaces
, vol.87
, pp. 319-325
-
-
Lou, H.1
Gao, L.2
Wei, X.3
Zhang, Z.4
Zheng, D.5
Zhang, D.6
Zhang, X.7
Li, Y.8
Zhang, Q.9
-
135
-
-
24144452456
-
Adsorption kinetics of plasma proteins on solid lipid nanoparticles for drug targeting
-
DOI 10.1016/j.ijpharm.2005.06.025, PII S0378517305004540
-
T.M. Goppert, R.H. Müller, Adsorption kinetics of plasma proteins on solid lipid nanoparticles for drug targeting, Int. J. Pharm. 302 (2005) 172-186. (Pubitemid 41242762)
-
(2005)
International Journal of Pharmaceutics
, vol.302
, Issue.1-2
, pp. 172-186
-
-
Goppert, T.M.1
Muller, R.H.2
-
136
-
-
70350782346
-
Formulation of nanosuspensions as a new approach for the delivery of poorly soluble drugs
-
X. Pu, J. Sun, M. Li, Z. He, Formulation of nanosuspensions as a new approach for the delivery of poorly soluble drugs, Curr. Nanosci. 5 (2009) 417-427.
-
(2009)
Curr. Nanosci.
, vol.5
, pp. 417-427
-
-
Pu, X.1
Sun, J.2
Li, M.3
He, Z.4
-
137
-
-
63949084823
-
Recent perspectives in ocular drug delivery
-
R. Gaudana, J. Jwala, S.H.S. Boddu, A.K. Mitra, Recent perspectives in ocular drug delivery, Pharm. Res. 26 (2009) 1197-1216.
-
(2009)
Pharm. Res.
, vol.26
, pp. 1197-1216
-
-
Gaudana, R.1
Jwala, J.2
Boddu, S.H.S.3
Mitra, A.K.4
-
138
-
-
0032848664
-
Targeted delivery of anti-angiogenic agent TNP-470 using water-soluble polymer in the treatment of choroidal neovascularization
-
T. Yasukawa, H. Kimura, Y. Tabata, H. Miyamoto, Y. Honda, Y. Ikada, Y. Ogura, Targeted delivery of anti-angiogenic agent TNP-470 using water-soluble polymer in the treatment of choroidal neovascularization, Invest. Ophthalmol. Vis. Sci. 40 (1999) 2690-2696. (Pubitemid 29455501)
-
(1999)
Investigative Ophthalmology and Visual Science
, vol.40
, Issue.11
, pp. 2690-2696
-
-
Yasukawa, T.1
Kimura, H.2
Tabata, Y.3
Miyamoto, H.4
Honda, Y.5
Ikada, Y.6
Ogura, Y.7
-
139
-
-
77955274105
-
Delivery of amphotericin B nanosuspensions to the brain and determination of activity against Balamuthia mandrillaris amebas
-
A. Lemke, A.F. Kiderlen, B. Petri, O. Kayser, Delivery of amphotericin B nanosuspensions to the brain and determination of activity against Balamuthia mandrillaris amebas, Nanomedicine 6 (2010) 597-603.
-
(2010)
Nanomedicine
, vol.6
, pp. 597-603
-
-
Lemke, A.1
Kiderlen, A.F.2
Petri, B.3
Kayser, O.4
-
140
-
-
84859958800
-
Nanotechnological advances for the delivery of CNS therapeutics
-
doi:10.1016/j.addr.2011.10.007
-
H.L. Wong, X.Y. Wu, R. Bendayan, Nanotechnological advances for the delivery of CNS therapeutics, Adv. Drug Deliv. Rev. (2011), doi:10.1016/j.addr. 2011.10.007.
-
(2011)
Adv. Drug Deliv. Rev.
-
-
Wong, H.L.1
Wu, X.Y.2
Bendayan, R.3
-
141
-
-
45249092544
-
Use of nanoparticles for cerebral cancer
-
J. Kreuter, S. Gelperina, Use of nanoparticles for cerebral cancer, Tumori 94 (2008) 271-277. (Pubitemid 351838835)
-
(2008)
Tumori
, vol.94
, Issue.2
, pp. 271-277
-
-
Kreuter, J.1
Gelperina, S.2
-
142
-
-
0028911362
-
Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles)
-
J. Kreuter, R.N. Alyautdin, D.A. Kharkevich, A.A. Ivanov, Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles), Brain Res. 674 (1995) 171-174.
-
(1995)
Brain Res.
, vol.674
, pp. 171-174
-
-
Kreuter, J.1
Alyautdin, R.N.2
Kharkevich, D.A.3
Ivanov, A.A.4
-
143
-
-
0035937595
-
Nanoparticulate systems for brain delivery of drugs
-
DOI 10.1016/S0169-409X(00)00122-8, PII S0169409X00001228
-
J. Kreuter, Nanoparticulate systems for brain delivery of drugs, Adv. Drug Deliv. Rev. 47 (2001) 65-81. (Pubitemid 32209233)
-
(2001)
Advanced Drug Delivery Reviews
, vol.47
, Issue.1
, pp. 65-81
-
-
Kreuter, J.1
-
144
-
-
18744413936
-
Polysorbate-stabilized solid lipid nanoparticles as colloidal carriers for intravenous targeting of drugs to the brain: Comparison of plasma protein adsorption patterns
-
T.M. Göppert, R.H. Müller, Polysorbate-stabilized solid lipid nanoparticles as colloidal carriers for intravenous targeting of drugs to the brain: comparison of plasma protein adsorption patterns, J. Drug Target. 13 (2005) 179-187.
-
(2005)
J. Drug Target.
, vol.13
, pp. 179-187
-
-
Göppert, T.M.1
Müller, R.H.2
-
145
-
-
28744456012
-
Characterization of folate-chitosan-DNA nanoparticles for gene therapy
-
DOI 10.1016/j.biomaterials.2005.09.020, PII S0142961205008628
-
S. Mansouri, Y. Cuie, F. Winnik, Q. Shi, P. Lavigne, M. Benderdour, E. Beaumont, J.C. Fernandes, Characterization of folate-chitosan-DNA nanoparticles for gene therapy, Biomaterials 27 (2006) 2060-2065. (Pubitemid 41759500)
-
(2006)
Biomaterials
, vol.27
, Issue.9
, pp. 2060-2065
-
-
Mansouri, S.1
Cuie, Y.2
Winnik, F.3
Shi, Q.4
Lavigne, P.5
Benderdour, M.6
Beaumont, E.7
Fernandes, J.C.8
-
146
-
-
27944455140
-
Folate receptor-mediated drug targeting: From therapeutics to diagnostics
-
DOI 10.1002/jps.20457
-
A.R. Hilgenbrink, P.S. Low, Folate receptor-mediated drug targeting: from therapeutics to diagnostics, J. Pharm. Sci. 94 (2005) 2135-2146. (Pubitemid 41665275)
-
(2005)
Journal of Pharmaceutical Sciences
, vol.94
, Issue.10
, pp. 2135-2146
-
-
Hilgenbrink, A.R.1
Low, P.S.2
-
147
-
-
36849065709
-
Cell-based drug delivery
-
DOI 10.1016/j.addr.2007.08.029, PII S0169409X07002505, Emerging Trends in Cell-Based Therapies
-
F. Pierigè, S. Serafini, L. Rossi, M. Magnani, Cell-based drug delivery, Adv. Drug Deliv. Rev. 60 (2008) 286-295. (Pubitemid 350236405)
-
(2008)
Advanced Drug Delivery Reviews
, vol.60
, Issue.2
, pp. 286-295
-
-
Pierige, F.1
Serafini, S.2
Rossi, L.3
Magnani, M.4
-
148
-
-
23644437163
-
Therapeutic potential of nanoparticulate systems for macrophage targeting
-
DOI 10.1016/j.biomaterials.2005.05.044, PII S0142961205004497, Canadian Biomaterials Research
-
F. Chellat, Y. Merhi, A. Moreau, L. Yahia, Therapeutic potential of nanoparticulate systems for macrophage targeting, Biomaterials 26 (2005) 7260-7275. (Pubitemid 41133578)
-
(2005)
Biomaterials
, vol.26
, Issue.35
, pp. 7260-7275
-
-
Chellat, F.1
Merhi, Y.2
Moreau, A.3
Yahia, L.4
-
149
-
-
34250325127
-
Identification of peptide ligands facilitating nanoparticle attachment to erythrocytes
-
DOI 10.1021/bp060333l
-
S.S. Hall, S. Mitragotri, P.S. Daugherty, Identification of peptide ligands facilitating nanoparticle at attachment to erythrocytes, Biotechnol. Prog. 23 (2007) 749-754. (Pubitemid 46911204)
-
(2007)
Biotechnology Progress
, vol.23
, Issue.3
, pp. 749-754
-
-
Hall, S.S.1
Mitragotri, S.2
Daugherty, P.S.3
-
150
-
-
33750436256
-
Quantitative magnetic resonance and SPECT imaging for macrophage tissue migration and nanoformulated drug delivery
-
DOI 10.1189/jlb.0206110
-
S. Gorantla, H. Dou, M. Boska, C.J. Destache, J. Nelson, L. Poluektova, B.E. Rabinow, H.E. Gendelman, R.L. Mosley, Quantitative magnetic resonance and SPECT imaging for macrophage tissue migration and nanoformulated drug delivery, J. Leukoc. Biol. 80 (2006) 1165-1174. (Pubitemid 44646322)
-
(2006)
Journal of Leukocyte Biology
, vol.80
, Issue.5
, pp. 1165-1174
-
-
Gorantla, S.1
Dou, H.2
Boska, M.3
Destache, C.J.4
Nelson, J.5
Poluektova, L.6
Rabinow, B.E.7
Gendelman, H.E.8
Mosley, R.L.9
-
151
-
-
0037451745
-
Delivery to macrophages and toxic action of etoposide carried in mouse red blood cells
-
DOI 10.1016/S0304-4165(02)00536-6
-
L.A. Lotero, G. Olmos, J.C. Diez, Delivery to macrophages and toxic action of etoposide carried inmouse red blood cells, Biochim. Biophys. Acta 1620 (2003) 160-166. (Pubitemid 36197907)
-
(2003)
Biochimica et Biophysica Acta - General Subjects
, vol.1620
, Issue.1-3
, pp. 160-166
-
-
Lotero, L.A.1
Olmos, G.2
Diez, J.C.3
-
152
-
-
23644444447
-
Erythrocyte-based drug delivery
-
DOI 10.1517/17425247.2.2.311
-
L. Rossi, S. Serafini, F. Pierigé, A. Antonelli, A. Cerasi, A. Fraternale, L. Chiarantini, M. Magnani, Erythrocyte-based drug delivery, Expert Opin. Drug Deliv. 2 (2005) 311-322. (Pubitemid 41130885)
-
(2005)
Expert Opinion on Drug Delivery
, vol.2
, Issue.2
, pp. 311-322
-
-
Rossi, L.1
Serafini, S.2
Pierige, F.3
Antonelli, A.4
Cerasi, A.5
Fraternale, A.6
Chiarantini, L.7
Magnani, M.8
-
153
-
-
4444356205
-
Drug delivery through phagocytosis of red blood cells
-
DOI 10.1159/000078042
-
S. Serafini, L. Rossi, A. Antonelli, A. Fraternale, A. Cerasi, R. Crinelli, L. Chiarantini, G.F. Schiavano, M. Magnani, Drug delivery through phagocytosis of red blood cells, Transfus. Med. Hemother. 31 (2004) 92-101. (Pubitemid 39177742)
-
(2004)
Transfusion Medicine and Hemotherapy
, vol.31
, Issue.2
, pp. 92-101
-
-
Serafini, S.1
Rossi, L.2
Antonelli, A.3
Fraternale, A.4
Cerasi, A.5
Crinelli, R.6
Chiarantini, L.7
Schiavano, G.F.8
Magnani, M.9
-
154
-
-
33750611615
-
Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery
-
H. Dou, C.J. Destache, J.R. Morehead, R. Lee Mosley, M.D. Boska, J. Kingsley, S. Gorantla, L. Poluektova, J.A. Nelson, M. Chaubal, J. Werling, J. Kipp, B.E. Rabinow, H.E. Gendelman, Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery, Blood 108 (2006) 2827-2835.
-
(2006)
Blood
, vol.108
, pp. 2827-2835
-
-
Dou, H.1
Destache, C.J.2
Morehead, J.R.3
Lee Mosley, R.4
Boska, M.D.5
Kingsley, J.6
Gorantla, S.7
Poluektova, L.8
Nelson, J.A.9
Chaubal, M.10
Werling, J.11
Kipp, J.12
Rabinow, B.E.13
Gendelman, H.E.14
-
155
-
-
73949146977
-
In vitro inhibition of fungal activity by macrophage-mediated sequestration and release of encapsulated amphotericin B nanosuspension in red blood cells
-
V. Staedtke, M. Bräler, A. Müller, R. Georgieva, S. Bauer, N. Sternberg, A. Voigt, A. Lemke, C. Keck, J. Möschwitzer, H. Bäumler, In vitro inhibition of fungal activity by macrophage-mediated sequestration and release of encapsulated amphotericin B nanosuspension in red blood cells, Small 6 (2010) 96-103.
-
(2010)
Small
, vol.6
, pp. 96-103
-
-
Staedtke, V.1
Bräler, M.2
Müller, A.3
Georgieva, R.4
Bauer, S.5
Sternberg6
|