Use of nanoparticles for cerebral cancer

Tumori

Volumn 94, Issue 2, 2008, Pages 271-277

  Kreuter, Jörg ^a   Gelperina, Svetlana ^b  

^a GOETHE UNIVERSITY   (Germany)

^b Nanosystem LTD   (Russian Federation)

Author keywords

Apolipoproteins; Doxorubicin; Glioblastoma; Nanoparticles; Poly(butyl cyanoacrylate); Poly(lactide co glycolic acid)

Indexed keywords

ACRYLIC ACID DERIVATIVE; APOLIPOPROTEIN; DOXORUBICIN; GLYCOPROTEIN P; NANOPARTICLE; POLOXAMER; POLOXAMINE 908; POLY(ALKYL 2 CYANOACRYLATE); POLY(BUTYL CYANOACRYLATE); POLYGLACTIN; POLYSORBATE 80;

BLOOD BRAIN BARRIER; BRAIN CAPILLARY; BRAIN TUMOR; CARDIOTOXICITY; CONFERENCE PAPER; CONFOCAL LASER MICROSCOPY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG FORMULATION; DRUG TRANSPORT; DRUG UPTAKE; GLIOBLASTOMA; GLIOSARCOMA; HUMAN; MULTIPLE CYCLE TREATMENT; NONHUMAN; RADIATION STERILIZATION; TUMOR REGRESSION;

EID: 45249092544     PISSN: 03008916     EISSN: None     Source Type: Journal    
DOI: 10.1177/030089160809400220     Document Type: Conference Paper

References (43)

1. DeAngelis LM: Brain Tumors. N Engl J Med, 344: 114-123, 2001.
2. Kornblith PL, Walker M: Chemotherapy for malignant gliomas. J Neurosurg, 68: 1-17, 1988.
3. Reardon DA, Wen PY: Therapeutic advances in the treatment of glioblastoma: rationale and potential role of targeted agents. The Oncologist, 11: 152-164, 2006.
4. Huncharek M, Muscat J Geschwind JF: Multi-drug versus single agent chemotherapy for high grade astrocytoma; results of a meta-analysis. Anticancer Res, 18: 4693-4697, 1998.
5. Brandes AA, Pasetto LM, Monfardini S: New drugs in recurrent high grade gliomas. Anticancer Res, 20: 1913-1920, 2000.
6. Robinson PJ: Osmotic opening of the blood-brain barrier and brain tumor chemotherapy. In: Methods in Neurosciences, pp 35-50, 1994.
7. Roullin V-G, Deverre J-R, Lemaire L, Hindré F, Venier-Julienne M-C, Vienet R, Benoit J-P: Anti-cancer drug diffusion within living rat brain tissue: an experimental study using [3H](6)-5-fluorouracil-loaded PLGA microspheres. Eur J Pharm Biopharm, 53: 293-299, 2002.
8. Kreuter J: Nanoparticulate systems for brain delivery of drugs. Adv Drug Deliv Rev, 47: 65-81, 2001.
9. Kreuter J: Transport of drugs across the blood-brain barrier by nanoparticles. Curr Med Chem - Centr Nerv Syst Agents, 2: 241-249, 2002.
10. Kreuter J: Nanoparticles as drug delivery systems for the brain. In: Microencapsulation, Methods and Industrial Applications, Benita S (Ed), 2nd ed, pp 689-706, Taylor and Francis, New York, USA, 2006.
11. Kreuter J: Nanoparticulate carriers for drug delivery to the brain. In: Nanoparticles as Drug Carriers, Torchilin VP (Ed), pp 527-547, Imperial College Press, London, 2006.
12. Gelperina S: Brain delivery by nanoparticles. In: Nanoparticle Technology for Drug Delivery, Gupta RB, Kompella UB, pp 273-318, Taylor and Francis, New York, USA, 2006.
13. Kreuter J: Nanoparticles. In: Encyclopedia of Pharmaceutical Technology, Vol 10, Swarbrick J, Boylan JC (Eds), pp 165-190, M Dekker, New York, 1994.
14. Gulyaev AE, Gelperina SE, Skidan IN, Antropov AS, Kivman, GYa, Kreuter J: Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles. Pharm Res, 16; 1564-1569, 1999.
15. Steiniger SCJ, Kreuter J, Khalansky AS, Skidan IN, Bobruskin AI, Smirnova ZS, Severin SE, Uhl R, Kock M, Geiger, KD, Gelperina SE: Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles. Int J Cancer, 109: 759-767, 2004.
16. Ambruosi A, Gelperina S, Khalansky AS, Tanski S, Theisen, A, Kreuter J: Influence of surfactants, polymer, and doxorubicin loading on the anti-tumour effect of poly(butyl cyanoacrylate) nanoparticles in a rat glioma model. J Microencapsul, 23: 582-592, 2006.
17. Petri B, Bootz A, Khalansky A, Hekmatara T, Müller R, Uhl R, Kreuter J, Gelperina S: Chemotherapy of brain tumour using doxorubicin bound to surfactant-coated poly(butyl cyanoacrylate) nanoparticles: Revisiting the role of surfactants. J Controlled Rel, 117: 51-58, 2007.
18. Alyautdin RN, Petrov VE, Langer K, Berthold A, Kharkevich DA, Kreuter J: Delivery of loperamide across the blood-brain barrier with polysorbate 80-coated polybutylcyanoacrylate nanoparticles. Pharm Res, 14: 325-328, 1997.
19. Michaelis K, Hoffmann MM, Dreis S, Herbert E, Alyautdin RN, Michaelis M, Kreuter J, Langer K: Covalent linkage of apolipoprotein E to albumin-nanoparticles strongly enhances drug transport into the brain. J Pharmacol Exp Ther, 317: 1246-1253, 2006.
20. Kreuter J, Hekmatara T, Dreis S, Vogel T, Gelperina S, Langer K: Covalent attachment of apolipoprotein AI and apolipoprotein B-100 to albumin nanoparticles enables drug transport into the brain. J Controlled Rel, 118: 54-58, 2007.
21. Alyautdin RN, Tezikov EB, Ramge P, Kharkevich DA, Begley DJ, Kreuter J: Significant entry of tubocurarine into the brain of rats by absorption to polysorbate 80-coated polybutyl-cyanoacrylate nanoparticles: an in situ brain perfusion study. J Microencapsul, 15: 67-74, 1998.
22. Kreuter J, Alyautdin RN, Kharkevich DA, Ivanov AA: Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles). Brain Res, 674: 171-174, 1995.
23. Kreuter J, Ramge P, Petrov V, Hamm S, Gelperina SE, Engelhardt B, Alyautdin R, von Briesen H, Begley DJ: Direct evidence that polysorbate 80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drugs to nanoparticles. Pharm Res, 20: 409-416, 2003.
24. Schroeder U, Sommerfeld P, Ulrich S, Sabel BA: Nanoparticle technology for delivery of drugs across the blood-brain barrier. J Pharm Sci, 87: 1305-1307, 1998.
25. Friese A, Seiller E, Quack G, Lorenz B, Kreuter J: Increase of the duration of the anticonvulsive activity of a novel NM-DA receptor antagonist using poly(butylcyanoacylate) nanoparticles as a parenteral controlled release system. Eur J Pharm Biopharm, 49: 103-109, 2000.
26. Stan AC, Casares S, Radu D, Walter GF, Brumeanu TD: Doxorubicin-induced cell death in highly invasive human gliomas. Anticancer Res, 19: 941-950, 1999.
27. Sanchez de Juan B, von Briesen H, Gelperina SE, Kreuter J: Cytotoxicity of doxorubicin bound to poly(butyl cyanoacrylate) nanoparticles in rat glioma cell lines using different assays. J Drug Target 14: 614-622, 2006.
28. Couvreur P, Grislain L, Lenaerts V, Brasseur F, Guiot P, Biernacki A: Biodegradable polymeric nanoparticles as drug carrier for antitumor agents. In: Polymeric Nanoparticles and Microspheres, Guiot P, Couvreur P (Eds), pp 27-93, CRC Press, Boca Raton, USA, 1986.
29. Kattan J, Droz JP, Couvreur P, Marino J-P, Boutan-Laroze A, Rougier P, Brault P, Vranckx H, Grognet J-M, Morge X, Sancho-Garnier H: Phase I clinical trial and pharmacokinetic evaluation of doxorubicin carried by polyisohexylcyanoacrylate nanoparticles. Invest New Drugs, 10: 191-199, 1992.
30. Borchard G, Audus KL, Shi F, Kreuter J: Uptake of surfactant-coated poly(methyl methacrylate)-nanoparticles by bovine brain microvessel endothelial cell monolayers. Int J Pharm, 110: 29-35, 1994.
31. Ramge P, Unger RE, Oltrogge JB, Zenker D, Begley D, Kreuter J, von Briesen H: Polysorbate 80-coating enhances uptake of polybutylcyanoacrylate (PBCA)-nanoparticles by human and bovine primary brain capillary endothelial cells. Europ J Neurosci 12, 1931-1940, 2000.
32. Alyautdin RN, Reichel A, Löbenberg R, Ramge P, Kreuter J, Begley DJ: Interaction of poly-(butylcyanoacrylate) nanoparticles with the blood-brain barrier in vivo and in vitro. J Drug Target 9: 209-221, 2001.
33. Couvreur P, Kante B, Grislain L, Roland M, Speiser P: Toxicity of polyalkylcyanoacrylate nanoparticles II: Doxorubicin-loaded nanoparticles. J Pharm Sci, 71: 790-792, 1982.
34. Ambruosi A, Khalansky AS, Yamamoto H, Gelperina SE, Begley, DJ, Kreuter J: Biodistribution of polysorbate 80-coated doxorubicin-loaded [14C]-poly-(butyl cyanoacrylate) nanoparticles after intravenous administration to glioblastoma-bearing rats. J Drug Target 14, 97-105, 2006.
35. Ambruosi A, Yamamoto H, Kreuter J: Body distribution of polysorbate-80 and doxorubicin-loaded [14C]poly(butyl cyanoacrylate) nanoparticles after i.v. administration in rats. J Drug Target 13, 535-542, 2005.
36. Brigger I, Morizet J, Aubert G, Chacun H, Terrier-Lacombe M-J, Couvreur P, Vassal G: Poly(ethylene glycol)-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting. J Pharmacol Exp Ther, 303: 928-936, 2002.
37. Maeda H: The enhanced permeability and retention (EPR) effect in tumour vasculature: the key role of tumour-selective macromolecular drug targeting. Adv Enzyme Regul, 41: 189-207, 2001.
38. Brigger I, Morizet J, Laudani L, Aubert G, Appel M, Velasco V, Terrier-Lacombe M-J, Desmaele D, d'Angelo J, Couvreur P, Vassal G: Negative preclinical results with stealth® nanosphere-encapsulated doxorubicin in an orthotropic murine brain tumor model. J Controlled Rel, 100: 29-40, 2004.
39. Gelperina SE, Khalansky AS, Skidan IN, Smirnova ZS, Bobruskin AI, Severin SE,1 Turowski B, Zanella FE, Kreuter J: Toxicological studies of doxorubicin bound to polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma. Toxicol Letters, 126: 131-141, 2002.
40. Pereverzeva E, Treschalin I, Bodyagin D, Maksimenko O, Langer K, Dreis S, Asmussen B, Kreuter J, Gelperina S: Influence of the formulation on the tolerance profile of nanoparticle-bound doxorubicin in healthy rats: Focus on cardio- and testicular toxicity. Int J Pharm, 337: 346-356, 2007.
41. Pereverzeva E, Treschalin I, Bodyagin D, Maksimenko O, Kreuter J, Gelperina S: Intravenous tolerance of a nanoparticle-based formulation of doxorubicin in healthy rats. Toxicol Letters, (in press).
42. Maksimenko A, Pavlov E, Toushov E, Molin A, Stukalov Y, Prudskova T, Feldman V, Kreuter J, Gelperina S: Radiation sterilisation of doxorubicin bound to poly(butyl cyanoacrylate) nanoparticles. Int J Pharm, 356: 325-332, 2008.
43. Lück M: Plasmaproteinadsorption als möglicher Schlüsselfaktor für eine kontrollierte Arzneistoffapplikation mit partikulären Trägern. PhD Thesis, Freie Universität Berlin, pp 14-24, 137-154, 1997.