-
1
-
-
38749119045
-
Effect of arginine hydrochloride and hydroxypropyl cellulose as stabilizers on the physical stability of high drug loading nanosuspensions of a poorly soluble compound
-
Ain-Ai A., and Gupta P.K. Effect of arginine hydrochloride and hydroxypropyl cellulose as stabilizers on the physical stability of high drug loading nanosuspensions of a poorly soluble compound. Int. J. Pharm. 351 (2008) 282-288
-
(2008)
Int. J. Pharm.
, vol.351
, pp. 282-288
-
-
Ain-Ai, A.1
Gupta, P.K.2
-
2
-
-
53949112927
-
-
Avantium. http://www.avantium.com/index.php.
-
Avantium. http://www.avantium.com/index.php.
-
-
-
-
3
-
-
53949107478
-
-
British Standards Institution, 2005. PAS 71:2005-Vocabulary-Nanoparticles. http://www.bsi-global.com/upload/Standards%20&%20Publications/Nanotechnologies/PAS71.pdf.
-
British Standards Institution, 2005. PAS 71:2005-Vocabulary-Nanoparticles. http://www.bsi-global.com/upload/Standards%20&%20Publications/Nanotechnologies/PAS71.pdf.
-
-
-
-
4
-
-
12444256027
-
A high-throughput combinatorial approach for the discovery of a cremophor EL-free paclitaxel formulation
-
Chen H., Zhang Z., McNulty C., Olbert C., Yoon H.J., Lee J.W., Kim S.C., Seo M.H., Oh H.S., Lemmo A.V., Ellis S.J., and Heimlich K. A high-throughput combinatorial approach for the discovery of a cremophor EL-free paclitaxel formulation. Pharm. Res. 20 (2003) 1302-1308
-
(2003)
Pharm. Res.
, vol.20
, pp. 1302-1308
-
-
Chen, H.1
Zhang, Z.2
McNulty, C.3
Olbert, C.4
Yoon, H.J.5
Lee, J.W.6
Kim, S.C.7
Seo, M.H.8
Oh, H.S.9
Lemmo, A.V.10
Ellis, S.J.11
Heimlich, K.12
-
5
-
-
34548331724
-
1,3-Dicyclohexyl urea nanosuspension for intravenous steady-state delivery in rats
-
Chiang P.C., Wahlstrom J.L., Selbo J.G., Zhou S., Wene S.P., Albin L.A., Warren C.J., Smith M.E., Roberds S.L., Ghosh S., Zhang L.L., and Pretzer D.K. 1,3-Dicyclohexyl urea nanosuspension for intravenous steady-state delivery in rats. J. Exp. Nanosci. 2 (2007) 239-250
-
(2007)
J. Exp. Nanosci.
, vol.2
, pp. 239-250
-
-
Chiang, P.C.1
Wahlstrom, J.L.2
Selbo, J.G.3
Zhou, S.4
Wene, S.P.5
Albin, L.A.6
Warren, C.J.7
Smith, M.E.8
Roberds, S.L.9
Ghosh, S.10
Zhang, L.L.11
Pretzer, D.K.12
-
6
-
-
19144364655
-
Role of polymeric stabilizers for drug nanocrystal dispersions
-
Choi J.Y., Yoo J.Y., Kwak H.S., Nam B.U., and Lee J. Role of polymeric stabilizers for drug nanocrystal dispersions. Curr. Appl. Phys. 5 (2005) 472-474
-
(2005)
Curr. Appl. Phys.
, vol.5
, pp. 472-474
-
-
Choi, J.Y.1
Yoo, J.Y.2
Kwak, H.S.3
Nam, B.U.4
Lee, J.5
-
7
-
-
33846783997
-
Turbidimetric measurement and prediction of dissolution rates of poorly soluble drug nanocrystals
-
Crisp M.T., Tucker C.J., Rogers T.L., Williams R.O., and Johnston K.P. Turbidimetric measurement and prediction of dissolution rates of poorly soluble drug nanocrystals. J. Control. Release 117 (2007) 351-359
-
(2007)
J. Control. Release
, vol.117
, pp. 351-359
-
-
Crisp, M.T.1
Tucker, C.J.2
Rogers, T.L.3
Williams, R.O.4
Johnston, K.P.5
-
8
-
-
53949108129
-
-
Cunningham, J., Merisko-Liversidge, E., Cooper, E.R., Liversidge, G.G., 15 July 2004. Milling microgram quantities of nanoparticulate candidate compounds. World Patent WO 2004/058216 A2.
-
Cunningham, J., Merisko-Liversidge, E., Cooper, E.R., Liversidge, G.G., 15 July 2004. Milling microgram quantities of nanoparticulate candidate compounds. World Patent WO 2004/058216 A2.
-
-
-
-
9
-
-
34047271049
-
Parallel screening approach to identify solubility-enhancing formulations for improved bioavailability of a poorly water-soluble compound using milligram quantities of material
-
Dai W.G., Dong L.C., Li S., Pollock-Dove C., Chen J., Mansky P., and Eichenbaum G. Parallel screening approach to identify solubility-enhancing formulations for improved bioavailability of a poorly water-soluble compound using milligram quantities of material. Int. J. Pharm. 336 (2007) 1-11
-
(2007)
Int. J. Pharm.
, vol.336
, pp. 1-11
-
-
Dai, W.G.1
Dong, L.C.2
Li, S.3
Pollock-Dove, C.4
Chen, J.5
Mansky, P.6
Eichenbaum, G.7
-
11
-
-
39049103837
-
Understanding a relaxation behavior in a nanoparticle suspension for drug delivery applications
-
Deng Z., Xu S., and Li S. Understanding a relaxation behavior in a nanoparticle suspension for drug delivery applications. Int. J. Pharm. 351 (2008) 236-243
-
(2008)
Int. J. Pharm.
, vol.351
, pp. 236-243
-
-
Deng, Z.1
Xu, S.2
Li, S.3
-
12
-
-
0000134186
-
Theory of the stability of strongly charged lyophobic sols and of the adhesion of strongly charged particles in solutions of electrolytes
-
Derjaguin B.V., and Landau L. Theory of the stability of strongly charged lyophobic sols and of the adhesion of strongly charged particles in solutions of electrolytes. Acta Phys. Chim. 14 (1941) 633-662
-
(1941)
Acta Phys. Chim.
, vol.14
, pp. 633-662
-
-
Derjaguin, B.V.1
Landau, L.2
-
14
-
-
53949121854
-
-
Elan. http://www.elan.com.
-
Elan. http://www.elan.com.
-
-
-
-
15
-
-
0032054501
-
Innovative strategies for the oral delivery of drugs and peptides
-
Fasano A. Innovative strategies for the oral delivery of drugs and peptides. TIBTECH 16 (1998) 152-157
-
(1998)
TIBTECH
, vol.16
, pp. 152-157
-
-
Fasano, A.1
-
16
-
-
53949099873
-
-
FDA Orange Book. http://www.fda.gov/cder/ob/default.htm.
-
FDA Orange Book. http://www.fda.gov/cder/ob/default.htm.
-
-
-
-
17
-
-
53949104228
-
-
Drugs@FDA. http://www.accessdata.fda.gov/scripts/cder/drugsatfda/.
-
Drugs@FDA. http://www.accessdata.fda.gov/scripts/cder/drugsatfda/.
-
-
-
-
18
-
-
53949088264
-
-
Feynman, R., 29 December 1959. There's plenty of room at the bottom (lecture). American Physical Society Meeting, Pasadena.
-
Feynman, R., 29 December 1959. There's plenty of room at the bottom (lecture). American Physical Society Meeting, Pasadena.
-
-
-
-
19
-
-
37549041747
-
Preparation and characterization of an oridonin nanosuspension for solubility and dissolution velocity enhancement
-
Gao L., Zhang D., Chen M., Zheng T., and Wang S. Preparation and characterization of an oridonin nanosuspension for solubility and dissolution velocity enhancement. Drug Dev. Ind. Pharm. 33 (2007) 1332-1339
-
(2007)
Drug Dev. Ind. Pharm.
, vol.33
, pp. 1332-1339
-
-
Gao, L.1
Zhang, D.2
Chen, M.3
Zheng, T.4
Wang, S.5
-
20
-
-
41349120910
-
Studies on pharmacokinetics and tissue distribution of oridonin nanosuspensions
-
Gao L., Zhang D., Chen M., Duan C., Dai W., Jia L., and Zhao W. Studies on pharmacokinetics and tissue distribution of oridonin nanosuspensions. Int. J. Pharm. 355 (2008) 321-327
-
(2008)
Int. J. Pharm.
, vol.355
, pp. 321-327
-
-
Gao, L.1
Zhang, D.2
Chen, M.3
Duan, C.4
Dai, W.5
Jia, L.6
Zhao, W.7
-
21
-
-
11144357547
-
Application of high throughput technologies to drug substance and drug product development
-
Gardner C.R., Almarsson O., Chen H., Morissette S., Peterson M., Zhang Z., Wang S., Lemmo A., Gonzalez-Zugasti J., Monagle J., Marchionna J., Ellis S., McNulty C., Johnson A., Levinson D., and Cima M. Application of high throughput technologies to drug substance and drug product development. Comput. Chem. Eng. 28 (2004) 943-953
-
(2004)
Comput. Chem. Eng.
, vol.28
, pp. 943-953
-
-
Gardner, C.R.1
Almarsson, O.2
Chen, H.3
Morissette, S.4
Peterson, M.5
Zhang, Z.6
Wang, S.7
Lemmo, A.8
Gonzalez-Zugasti, J.9
Monagle, J.10
Marchionna, J.11
Ellis, S.12
McNulty, C.13
Johnson, A.14
Levinson, D.15
Cima, M.16
-
23
-
-
4243483209
-
Suspension formulation
-
Nielloud F., and Marti-Mestres G. (Eds), Marcel Dekker, Inc., New York
-
Gonzáles-Caballero F., and de Dios Garciá López-Durán J. Suspension formulation. In: Nielloud F., and Marti-Mestres G. (Eds). Pharmaceutical Emulsions and Suspensions, Drugs and the Pharmaceutical Sciences vol. 105 (2000), Marcel Dekker, Inc., New York 127-190
-
(2000)
Pharmaceutical Emulsions and Suspensions, Drugs and the Pharmaceutical Sciences
, vol.105
, pp. 127-190
-
-
Gonzáles-Caballero, F.1
de Dios Garciá López-Durán, J.2
-
24
-
-
0033964139
-
Nanosuspensions of poorly soluble drugs-reproducibility of small scale production
-
Grau M.J., Kayser O., and Müller R.H. Nanosuspensions of poorly soluble drugs-reproducibility of small scale production. Int. J. Pharm. 196 (2000) 155-159
-
(2000)
Int. J. Pharm.
, vol.196
, pp. 155-159
-
-
Grau, M.J.1
Kayser, O.2
Müller, R.H.3
-
25
-
-
53949114467
-
Fundamentals of Drug Nanoparticles
-
Gupta R.B., and Kompella U.B. (Eds), Taylor & Francis Group, LLC, New York
-
Gupta R.B. Fundamentals of Drug Nanoparticles. In: Gupta R.B., and Kompella U.B. (Eds). Nanoparticle Technology for Drug Delivery, Drugs and the Pharmaceutical Sciences vol. 159 (2006), Taylor & Francis Group, LLC, New York 1-19
-
(2006)
Nanoparticle Technology for Drug Delivery, Drugs and the Pharmaceutical Sciences
, vol.159
, pp. 1-19
-
-
Gupta, R.B.1
-
26
-
-
34547863131
-
Pharmacokinetic evaluation of oral fenofibrate nanosuspensions and SLN in comparison to conventional suspensions of micronized drug
-
Hanafy A., Spahn-Langguth H., Vergnault G., Grenier P., Grozdanis M.T., Lenhardt T., and Langguth P. Pharmacokinetic evaluation of oral fenofibrate nanosuspensions and SLN in comparison to conventional suspensions of micronized drug. Adv. Drug Deliv. Rev. 59 (2007) 419-426
-
(2007)
Adv. Drug Deliv. Rev.
, vol.59
, pp. 419-426
-
-
Hanafy, A.1
Spahn-Langguth, H.2
Vergnault, G.3
Grenier, P.4
Grozdanis, M.T.5
Lenhardt, T.6
Langguth, P.7
-
27
-
-
53949120244
-
-
Hansell, R.J., 3 February 2005. Laboratory scale milling process. United States Patent US 2005/0023386 A.
-
Hansell, R.J., 3 February 2005. Laboratory scale milling process. United States Patent US 2005/0023386 A.
-
-
-
-
28
-
-
21844461846
-
Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipine
-
Hecq J., Deleers M., Fanara D., Vranckx H., and Amighi K. Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipine. Int. J. Pharm. 299 (2005) 167-177
-
(2005)
Int. J. Pharm.
, vol.299
, pp. 167-177
-
-
Hecq, J.1
Deleers, M.2
Fanara, D.3
Vranckx, H.4
Amighi, K.5
-
29
-
-
33750089277
-
Preparation and in vitro/in vivo evaluation of nano-sized crystals for dissolution rate enhancement of ucb-35440-3, a highly dosed poorly water-soluble weak base
-
Hecq J., Deleers M., Fanara D., Vranckx H., Boulanger P., Le Lamer S., and Amighi K. Preparation and in vitro/in vivo evaluation of nano-sized crystals for dissolution rate enhancement of ucb-35440-3, a highly dosed poorly water-soluble weak base. Eur. J. Pharm. Biopharm. 64 (2006) 360-368
-
(2006)
Eur. J. Pharm. Biopharm.
, vol.64
, pp. 360-368
-
-
Hecq, J.1
Deleers, M.2
Fanara, D.3
Vranckx, H.4
Boulanger, P.5
Le Lamer, S.6
Amighi, K.7
-
30
-
-
33846309257
-
Nifedipine nanocrystals: pharmacokinetic evaluation in the rat and permeability studies in Caco-2/HT29-5M21 (co)-cultures
-
Hecq J., Nollevaux G., Deleers M., Fanara D., Vranckx H., Peulen O., Dandrifosse G., and Amighi K. Nifedipine nanocrystals: pharmacokinetic evaluation in the rat and permeability studies in Caco-2/HT29-5M21 (co)-cultures. J. Drug Del. Sci. Technol. 16 (2006) 437-442
-
(2006)
J. Drug Del. Sci. Technol.
, vol.16
, pp. 437-442
-
-
Hecq, J.1
Nollevaux, G.2
Deleers, M.3
Fanara, D.4
Vranckx, H.5
Peulen, O.6
Dandrifosse, G.7
Amighi, K.8
-
31
-
-
33644799822
-
Characterization of nebulized buparvaquone nanosuspensions-effect of nebulization technology
-
Hernández-Trejo N., Kayser O., Steckel H., and Müller R.H. Characterization of nebulized buparvaquone nanosuspensions-effect of nebulization technology. J. Drug Target. 13 (2005) 499-507
-
(2005)
J. Drug Target.
, vol.13
, pp. 499-507
-
-
Hernández-Trejo, N.1
Kayser, O.2
Steckel, H.3
Müller, R.H.4
-
32
-
-
0035803697
-
Organic nanoparticles in the aqueous phase-theory, experiment, and use
-
Horn D., and Rieger J. Organic nanoparticles in the aqueous phase-theory, experiment, and use. Angew. Chem. Int. 40 (2001) 4331-4361
-
(2001)
Angew. Chem. Int.
, vol.40
, pp. 4331-4361
-
-
Horn, D.1
Rieger, J.2
-
33
-
-
1842559836
-
Nanoparticle engineering processes for enhancing the dissolution rates of poorly water soluble drugs
-
Hu J., Johnston K.P., and Williams R.O. Nanoparticle engineering processes for enhancing the dissolution rates of poorly water soluble drugs. Drug Dev. Ind. Pharm. 30 (2004) 233-245
-
(2004)
Drug Dev. Ind. Pharm.
, vol.30
, pp. 233-245
-
-
Hu, J.1
Johnston, K.P.2
Williams, R.O.3
-
35
-
-
0033956297
-
Nanosuspensions as a new approach for the formulation for the poorly soluble drug tarazepide
-
Jacobs C., Kayser O., and Müller R.H. Nanosuspensions as a new approach for the formulation for the poorly soluble drug tarazepide. Int. J. Pharm. 196 (2000) 161-164
-
(2000)
Int. J. Pharm.
, vol.196
, pp. 161-164
-
-
Jacobs, C.1
Kayser, O.2
Müller, R.H.3
-
36
-
-
0035910873
-
Production and characterisation of mucoadhesive nanosuspensions for the formulation of bupravaquone
-
Jacobs C., Kayser O., and Müller R.H. Production and characterisation of mucoadhesive nanosuspensions for the formulation of bupravaquone. Int. J. Pharm. 214 (2001) 3-7
-
(2001)
Int. J. Pharm.
, vol.214
, pp. 3-7
-
-
Jacobs, C.1
Kayser, O.2
Müller, R.H.3
-
37
-
-
0036176196
-
Production and characterization of a budesonide nanosuspension for pulmonary administration
-
Jacobs C., and Müller R.H. Production and characterization of a budesonide nanosuspension for pulmonary administration. Pharm. Res. 19 (2002) 189-194
-
(2002)
Pharm. Res.
, vol.19
, pp. 189-194
-
-
Jacobs, C.1
Müller, R.H.2
-
38
-
-
0001795346
-
The theory of high-pressure homogenization
-
Müller R.H., Benita S., and Böhm B.H.L. (Eds), Medpharm Scientific, Stuttgart
-
Jahnke S. The theory of high-pressure homogenization. In: Müller R.H., Benita S., and Böhm B.H.L. (Eds). Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs (1998), Medpharm Scientific, Stuttgart 177-200
-
(1998)
Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs
, pp. 177-200
-
-
Jahnke, S.1
-
39
-
-
0036689390
-
Effect of nanonization on absorption of 301029: ex vivo and in vivo pharmacokinetic correlations determined by liquid chromatography/mass spectrometry
-
Jia L., Wong H., Cerna C., and Weitman S.D. Effect of nanonization on absorption of 301029: ex vivo and in vivo pharmacokinetic correlations determined by liquid chromatography/mass spectrometry. Pharm. Res. 19 (2002) 1091-1096
-
(2002)
Pharm. Res.
, vol.19
, pp. 1091-1096
-
-
Jia, L.1
Wong, H.2
Cerna, C.3
Weitman, S.D.4
-
40
-
-
33344478634
-
Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs
-
Jinno J., Kamada N., Miyake M., Yamada K., Mukai T., Odomi M., Toguchi H., Liversidge G.G., Higaki K., and Kimura T. Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs. J. Control. Release 111 (2006) 56-64
-
(2006)
J. Control. Release
, vol.111
, pp. 56-64
-
-
Jinno, J.1
Kamada, N.2
Miyake, M.3
Yamada, K.4
Mukai, T.5
Odomi, M.6
Toguchi, H.7
Liversidge, G.G.8
Higaki, K.9
Kimura, T.10
-
41
-
-
13144268599
-
To be nano or not to be nano?
-
Joachim C. To be nano or not to be nano?. Nature Materials 4 (2005) 107-109
-
(2005)
Nature Materials
, vol.4
, pp. 107-109
-
-
Joachim, C.1
-
42
-
-
34447254990
-
Nanosuspension as an ophthalmic delivery system for certain glucocorticoid drugs
-
Kassem M.A., Rahman A.A.A., Ghorab M.M., Ahmed M.B., and Khalil R.M. Nanosuspension as an ophthalmic delivery system for certain glucocorticoid drugs. Int. J. Pharm. 340 (2007) 126-133
-
(2007)
Int. J. Pharm.
, vol.340
, pp. 126-133
-
-
Kassem, M.A.1
Rahman, A.A.A.2
Ghorab, M.M.3
Ahmed, M.B.4
Khalil, R.M.5
-
43
-
-
0037453179
-
Formulation of amphotericin B as nanosuspension for oral administration
-
Kayser O., Olbrich C., Yardley V., Kiderlen A.F., and Croft S.L. Formulation of amphotericin B as nanosuspension for oral administration. Int. J. Pharm. 254 (2003) 73-75
-
(2003)
Int. J. Pharm.
, vol.254
, pp. 73-75
-
-
Kayser, O.1
Olbrich, C.2
Yardley, V.3
Kiderlen, A.F.4
Croft, S.L.5
-
44
-
-
28444461830
-
Drug nanocrystals of poorly soluble drugs produced by high pressure homogenization
-
Keck C.M., and Müller R.H. Drug nanocrystals of poorly soluble drugs produced by high pressure homogenization. Eur. J. Pharm. Biopharm. 62 (2006) 3-16
-
(2006)
Eur. J. Pharm. Biopharm.
, vol.62
, pp. 3-16
-
-
Keck, C.M.1
Müller, R.H.2
-
45
-
-
34249790272
-
Application of nanoparticles in oral delivery of immediate release formulations
-
Kesisoglou F., Panmai S., and Wu Y. Application of nanoparticles in oral delivery of immediate release formulations. Curr. Nanosci. 3 (2007) 183-190
-
(2007)
Curr. Nanosci.
, vol.3
, pp. 183-190
-
-
Kesisoglou, F.1
Panmai, S.2
Wu, Y.3
-
46
-
-
34548049483
-
Nanosizing-oral formulation development and biopharmaceutical evaluation
-
Kesisoglou F., Panmai S., and Wu Y. Nanosizing-oral formulation development and biopharmaceutical evaluation. Adv. Drug Deliv. Rev. 59 (2007) 631-644
-
(2007)
Adv. Drug Deliv. Rev.
, vol.59
, pp. 631-644
-
-
Kesisoglou, F.1
Panmai, S.2
Wu, Y.3
-
47
-
-
5344234787
-
The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs
-
Kipp J.E. The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs. Int. J. Pharm. 284 (2004) 109-122
-
(2004)
Int. J. Pharm.
, vol.284
, pp. 109-122
-
-
Kipp, J.E.1
-
48
-
-
0027243792
-
Improved oral absorption of a poorly water-soluble drug, HO-221, by wet-bead milling producing particles in submicron region
-
Kondo N., Iwao T., Masuda H., Yamanouchi K., Ishihara Y., Yamada N., Haga T., Ogawa Y., and Yokoyama K. Improved oral absorption of a poorly water-soluble drug, HO-221, by wet-bead milling producing particles in submicron region. Chem. Pharm. Bull. 41 (1993) 737-740
-
(1993)
Chem. Pharm. Bull.
, vol.41
, pp. 737-740
-
-
Kondo, N.1
Iwao, T.2
Masuda, H.3
Yamanouchi, K.4
Ishihara, Y.5
Yamada, N.6
Haga, T.7
Ogawa, Y.8
Yokoyama, K.9
-
49
-
-
0035910878
-
Production and characterisation of highly concentrated nanosuspensions by high pressure homogenization
-
Krause K.P., and Müller R.H. Production and characterisation of highly concentrated nanosuspensions by high pressure homogenization. Int. J. Pharm. 214 (2001) 21-24
-
(2001)
Int. J. Pharm.
, vol.214
, pp. 21-24
-
-
Krause, K.P.1
Müller, R.H.2
-
50
-
-
34249824271
-
Improved bioavailability of albendazole following oral administration of nanosuspension in rats
-
Kumar M.P., Rao Y.M., and Apte S. Improved bioavailability of albendazole following oral administration of nanosuspension in rats. Curr. Nanosci. 3 (2007) 191-194
-
(2007)
Curr. Nanosci.
, vol.3
, pp. 191-194
-
-
Kumar, M.P.1
Rao, Y.M.2
Apte, S.3
-
51
-
-
41949130280
-
Formulation of nanosuspensions of albendazole for oral administration
-
Kumar M.P., Rao Y.M., and Apte S. Formulation of nanosuspensions of albendazole for oral administration. Curr. Nanosci. 4 (2008) 53-58
-
(2008)
Curr. Nanosci.
, vol.4
, pp. 53-58
-
-
Kumar, M.P.1
Rao, Y.M.2
Apte, S.3
-
52
-
-
16244398708
-
Nanosuspension formulations for low-soluble drugs: pharmacokinetic evaluation using spironolactone as model compound
-
Langguth P., Hanafy A., Frenzel D., Grenier P., Nhamias A., Ohlig T., Vergnault G., and Spahn-Langguth H. Nanosuspension formulations for low-soluble drugs: pharmacokinetic evaluation using spironolactone as model compound. Drug Dev. Ind. Pharm. 31 (2005) 319-329
-
(2005)
Drug Dev. Ind. Pharm.
, vol.31
, pp. 319-329
-
-
Langguth, P.1
Hanafy, A.2
Frenzel, D.3
Grenier, P.4
Nhamias, A.5
Ohlig, T.6
Vergnault, G.7
Spahn-Langguth, H.8
-
53
-
-
0141507950
-
Drug nano- and microparticles processed into solid dosage forms: physical properties
-
Lee J. Drug nano- and microparticles processed into solid dosage forms: physical properties. J. Pharm. Sci. 92 (2003) 2057-2068
-
(2003)
J. Pharm. Sci.
, vol.92
, pp. 2057-2068
-
-
Lee, J.1
-
54
-
-
15244348244
-
Amphiphilic amino acid copolymers as stabilizers for the preparation of nanocrystal dispersion
-
Lee J., Lee S.J., Choi J.Y., Yoo J.Y., and Ahn C.H. Amphiphilic amino acid copolymers as stabilizers for the preparation of nanocrystal dispersion. Eur. J. Pharm. Sci. 24 (2005) 441-449
-
(2005)
Eur. J. Pharm. Sci.
, vol.24
, pp. 441-449
-
-
Lee, J.1
Lee, S.J.2
Choi, J.Y.3
Yoo, J.Y.4
Ahn, C.H.5
-
55
-
-
33344464389
-
Critical freezing rate in freeze drying nanocrystal dispersions
-
Lee J., and Cheng Y. Critical freezing rate in freeze drying nanocrystal dispersions. J. Control. Release 111 (2006) 185-192
-
(2006)
J. Control. Release
, vol.111
, pp. 185-192
-
-
Lee, J.1
Cheng, Y.2
-
56
-
-
41349085155
-
Characteristics of polymers enabling nano-comminution of water-insoluble drugs
-
Lee J., Choi J.Y., and Park C.H. Characteristics of polymers enabling nano-comminution of water-insoluble drugs. Int. J. Pharm. 355 (2008) 328-336
-
(2008)
Int. J. Pharm.
, vol.355
, pp. 328-336
-
-
Lee, J.1
Choi, J.Y.2
Park, C.H.3
-
57
-
-
0036742053
-
Poor aqueous solubility-an industry wide problem in drug discovery
-
Lipinski C. Poor aqueous solubility-an industry wide problem in drug discovery. Am. Pharm. Rev. 5 (2002) 82-85
-
(2002)
Am. Pharm. Rev.
, vol.5
, pp. 82-85
-
-
Lipinski, C.1
-
58
-
-
53949099654
-
-
Liversidge, G.G., Phillips, C.P., Cundy, K.C., 12 April 1994. Method to reduce particle size growth during lyophilization. US Patent US 5,302,401 A.
-
Liversidge, G.G., Phillips, C.P., Cundy, K.C., 12 April 1994. Method to reduce particle size growth during lyophilization. US Patent US 5,302,401 A.
-
-
-
-
59
-
-
0028824401
-
Drug particle size reduction for decreasing gastric irritancy and enhancing absorption of naproxen in rats
-
Liversidge G.G., and Conzentino P. Drug particle size reduction for decreasing gastric irritancy and enhancing absorption of naproxen in rats. Int. J. Pharm. 125 (1995) 309-313
-
(1995)
Int. J. Pharm.
, vol.125
, pp. 309-313
-
-
Liversidge, G.G.1
Conzentino, P.2
-
60
-
-
0029080002
-
Particle size reduction for improvement of oral bioavailability of hydrophobic drugs. I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs
-
Liversidge G.G., and Cundy K.C. Particle size reduction for improvement of oral bioavailability of hydrophobic drugs. I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs. Int. J. Pharm. 125 (1995) 91-97
-
(1995)
Int. J. Pharm.
, vol.125
, pp. 91-97
-
-
Liversidge, G.G.1
Cundy, K.C.2
-
61
-
-
53949096775
-
-
Liversidge, G.G., Eickhoff, W.M., Ruddy, S.B., Mueller, K.R., Roberts, M.E., Engers, D.A., 20 August 1998. Formulations of nanoparticle naproxen tablets. World Patent WO 98/35666.
-
Liversidge, G.G., Eickhoff, W.M., Ruddy, S.B., Mueller, K.R., Roberts, M.E., Engers, D.A., 20 August 1998. Formulations of nanoparticle naproxen tablets. World Patent WO 98/35666.
-
-
-
-
62
-
-
34250746898
-
Screening method to identify preclinical liquid and semi-solid formulations for low solubility compounds: miniaturization and automation of solvent casting and dissolution testing
-
Mansky P., Dai W.G., Li S., Pollock-Dove C., Daehne K., Dong L., and Eichenbaum G. Screening method to identify preclinical liquid and semi-solid formulations for low solubility compounds: miniaturization and automation of solvent casting and dissolution testing. J. Pharm. Sci. 96 (2007) 1548-1563
-
(2007)
J. Pharm. Sci.
, vol.96
, pp. 1548-1563
-
-
Mansky, P.1
Dai, W.G.2
Li, S.3
Pollock-Dove, C.4
Daehne, K.5
Dong, L.6
Eichenbaum, G.7
-
63
-
-
0001923820
-
Main surfactants used in the pharmaceutical field
-
Nielloud F., and Marti-Mestres G. (Eds), Marcel Dekker, Inc., New York
-
Marti-Mestres G., and Nielloud F. Main surfactants used in the pharmaceutical field. In: Nielloud F., and Marti-Mestres G. (Eds). Pharmaceutical Emulsions and Suspensions, Drugs and the Pharmaceutical Sciences vol. 105 (2000), Marcel Dekker, Inc., New York 1-18
-
(2000)
Pharmaceutical Emulsions and Suspensions, Drugs and the Pharmaceutical Sciences
, vol.105
, pp. 1-18
-
-
Marti-Mestres, G.1
Nielloud, F.2
-
64
-
-
9044235775
-
Formulation and antitumor activity evaluation of nanocrystalline suspensions of poorly soluble anticancer drugs
-
Merisko-Liversidge E., Sarpotdar P., Bruno J., Hajj S., Wei L., Peltier N., Rake J., Shaw J.M., Pugh S., Polin L., Jones J., Corbett T., Cooper E., and Liversidge G.G. Formulation and antitumor activity evaluation of nanocrystalline suspensions of poorly soluble anticancer drugs. Pharm. Res. 13 (1996) 272-278
-
(1996)
Pharm. Res.
, vol.13
, pp. 272-278
-
-
Merisko-Liversidge, E.1
Sarpotdar, P.2
Bruno, J.3
Hajj, S.4
Wei, L.5
Peltier, N.6
Rake, J.7
Shaw, J.M.8
Pugh, S.9
Polin, L.10
Jones, J.11
Corbett, T.12
Cooper, E.13
Liversidge, G.G.14
-
65
-
-
53949097404
-
-
Merisko-Liversidge, E., Linden, W., 27 March 2003. Stabilization of active agents by formulation into nanoparticulate form. World Patent WO 03/024424 A1.
-
Merisko-Liversidge, E., Linden, W., 27 March 2003. Stabilization of active agents by formulation into nanoparticulate form. World Patent WO 03/024424 A1.
-
-
-
-
67
-
-
21644468027
-
Insulin nanoparticles: a novel formulation approach for poorly water soluble Zn-insulin
-
Merisko-Liversidge E., McGurk S.L., and Liversidge G.G. Insulin nanoparticles: a novel formulation approach for poorly water soluble Zn-insulin. Pharm. Res. 21 (2004) 1545-1553
-
(2004)
Pharm. Res.
, vol.21
, pp. 1545-1553
-
-
Merisko-Liversidge, E.1
McGurk, S.L.2
Liversidge, G.G.3
-
68
-
-
4644309307
-
Development of an intravenously injectable chemically stable aqueous omeprazole formulation using nanosuspension technology
-
Möschwitzer J., Achleitner G., Pomper H., and Müller R.H. Development of an intravenously injectable chemically stable aqueous omeprazole formulation using nanosuspension technology. Eur. J. Pharm. Biopharm. 58 (2004) 615-619
-
(2004)
Eur. J. Pharm. Biopharm.
, vol.58
, pp. 615-619
-
-
Möschwitzer, J.1
Achleitner, G.2
Pomper, H.3
Müller, R.H.4
-
69
-
-
33644820008
-
Spray coated pellets as carrier system for mucoadhesive drug nanocrystals
-
Möschwitzer J., and Müller R.H. Spray coated pellets as carrier system for mucoadhesive drug nanocrystals. Eur. J. Pharm. Biopharm. 62 (2006) 282-287
-
(2006)
Eur. J. Pharm. Biopharm.
, vol.62
, pp. 282-287
-
-
Möschwitzer, J.1
Müller, R.H.2
-
70
-
-
33845238460
-
Pharmacokinetics of itraconazole and hydroxyitraconazole in healthy subjects after single and multiple doses of a novel formulation
-
Mouton J.W., van Peer A., de Beule K., Van Vliet A., Donnelly J.P., and Soons P.A. Pharmacokinetics of itraconazole and hydroxyitraconazole in healthy subjects after single and multiple doses of a novel formulation. Antimicrob. Agents Chemother. 50 (2006) 4096-4102
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 4096-4102
-
-
Mouton, J.W.1
van Peer, A.2
de Beule, K.3
Van Vliet, A.4
Donnelly, J.P.5
Soons, P.A.6
-
71
-
-
0000451513
-
Nanosuspensions
-
Müller R.H., Benita S., and Böhm B.H.L. (Eds), Medpharm Scientific, Stuttgart
-
Müller R.H., and Böhm B.H.L. Nanosuspensions. In: Müller R.H., Benita S., and Böhm B.H.L. (Eds). Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs (1998), Medpharm Scientific, Stuttgart 149-174
-
(1998)
Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs
, pp. 149-174
-
-
Müller, R.H.1
Böhm, B.H.L.2
-
72
-
-
0342897023
-
Nanosuspensions for the formulation of poorly soluble drugs. I. Preparation by a size-reduction technique
-
Müller R.H., and Peters K. Nanosuspensions for the formulation of poorly soluble drugs. I. Preparation by a size-reduction technique. Int. J. Pharm. 2 (1998) 229-237
-
(1998)
Int. J. Pharm.
, vol.2
, pp. 229-237
-
-
Müller, R.H.1
Peters, K.2
-
73
-
-
0343339969
-
Nanosuspensions - formulations for poorly soluble drugs with poor bioavailability - 1st communication: production and properties
-
Müller R.H., Böhm B.H.L., and Grau M.J. Nanosuspensions - formulations for poorly soluble drugs with poor bioavailability - 1st communication: production and properties. Pharm. Ind. 61 (1999) 74-78
-
(1999)
Pharm. Ind.
, vol.61
, pp. 74-78
-
-
Müller, R.H.1
Böhm, B.H.L.2
Grau, M.J.3
-
74
-
-
0033025593
-
Nanosuspensions - formulations for poorly soluble drugs with poor bioavailability - 2nd communication: stability, biopharmaceutical aspects, possible drug forms and registration aspects
-
Müller R.H., Böhm B.H.L., and Grau M.J. Nanosuspensions - formulations for poorly soluble drugs with poor bioavailability - 2nd communication: stability, biopharmaceutical aspects, possible drug forms and registration aspects. Pharm. Ind. 61 (1999) 175-178
-
(1999)
Pharm. Ind.
, vol.61
, pp. 175-178
-
-
Müller, R.H.1
Böhm, B.H.L.2
Grau, M.J.3
-
75
-
-
0000595701
-
Nanosuspensions: a formulation approach for poorly soluble and poorly bioavailable drug
-
Wise D.L. (Ed), Marcel Dekker, Inc., New York
-
Müller R.H., Böhm B.H.L., and Grau M.J. Nanosuspensions: a formulation approach for poorly soluble and poorly bioavailable drug. In: Wise D.L. (Ed). Handbook of Pharmaceutical Controlled Release Technology (2000), Marcel Dekker, Inc., New York 345-357
-
(2000)
Handbook of Pharmaceutical Controlled Release Technology
, pp. 345-357
-
-
Müller, R.H.1
Böhm, B.H.L.2
Grau, M.J.3
-
76
-
-
0002819692
-
Nanosuspensions for the formulation of poorly soluble drugs
-
Nielloud F., and Marti-Mestres G. (Eds), Marcel Dekker, Inc., New York
-
Müller R.H., Jacobs C., and Kayser O. Nanosuspensions for the formulation of poorly soluble drugs. In: Nielloud F., and Marti-Mestres G. (Eds). Pharmaceutical Emulsions and Suspensions, Drugs and the Pharmaceutical Sciences vol. 105 (2000), Marcel Dekker, Inc., New York 383-407
-
(2000)
Pharmaceutical Emulsions and Suspensions, Drugs and the Pharmaceutical Sciences
, vol.105
, pp. 383-407
-
-
Müller, R.H.1
Jacobs, C.2
Kayser, O.3
-
77
-
-
0035937599
-
Nanosuspensions as particulate drug formulations in therapy-rationale for development and what we can expect for the future
-
Müller R.H., Jacobs C., and Kayser O. Nanosuspensions as particulate drug formulations in therapy-rationale for development and what we can expect for the future. Adv. Drug Deliv. Rev. 47 (2001) 3-19
-
(2001)
Adv. Drug Deliv. Rev.
, vol.47
, pp. 3-19
-
-
Müller, R.H.1
Jacobs, C.2
Kayser, O.3
-
78
-
-
0037177516
-
Buparvaquone mucoadhesive nanosuspension: preparation, optimisation and long-term stability
-
Müller R.H., and Jacobs C. Buparvaquone mucoadhesive nanosuspension: preparation, optimisation and long-term stability. Int. J. Pharm. 237 (2002) 151-161
-
(2002)
Int. J. Pharm.
, vol.237
, pp. 151-161
-
-
Müller, R.H.1
Jacobs, C.2
-
79
-
-
6344237328
-
DissoCubes-a novel formulation for poorly soluble and poorly bioavailable drugs
-
Rathborn M.J., Hadgraft J., and Roberts M.S. (Eds), Marcel Dekker, Inc., New York
-
Müller R.H., Kayser O., and Jacobs J. DissoCubes-a novel formulation for poorly soluble and poorly bioavailable drugs. In: Rathborn M.J., Hadgraft J., and Roberts M.S. (Eds). Modified-Release Drug Delivery Technology. Drugs and the Pharmaceutical Sciences vol. 126 (2003), Marcel Dekker, Inc., New York 135-149
-
(2003)
Modified-Release Drug Delivery Technology. Drugs and the Pharmaceutical Sciences
, vol.126
, pp. 135-149
-
-
Müller, R.H.1
Kayser, O.2
Jacobs, J.3
-
80
-
-
4544275025
-
Challenges and solutions for the delivery of biotech drugs-a review of drug nanocrystal technology and lipid nanoparticles
-
Müller R.H., and Keck C.M. Challenges and solutions for the delivery of biotech drugs-a review of drug nanocrystal technology and lipid nanoparticles. J. Biotechnol. 113 (2004) 151-170
-
(2004)
J. Biotechnol.
, vol.113
, pp. 151-170
-
-
Müller, R.H.1
Keck, C.M.2
-
81
-
-
33751163286
-
Manufacturing of nanoparticles by milling and homogenization techniques
-
Gupta R.B., and Kompella U.B. (Eds), Taylor & Francis Group, LLC, New York
-
Müller R.H., Möschwitzer J., and Bushrab F.N. Manufacturing of nanoparticles by milling and homogenization techniques. In: Gupta R.B., and Kompella U.B. (Eds). Nanoparticle Technology for Drug Delivery, Drugs and the Pharmaceutical Sciences vol. 159 (2006), Taylor & Francis Group, LLC, New York 21-51
-
(2006)
Nanoparticle Technology for Drug Delivery, Drugs and the Pharmaceutical Sciences
, vol.159
, pp. 21-51
-
-
Müller, R.H.1
Möschwitzer, J.2
Bushrab, F.N.3
-
82
-
-
0032950123
-
Physical Stability of Ethyl Diatrizoate Nanocrystalline Suspension in Steam Sterilization
-
Na G.C., Stevens H.J., Yuan B.O., and Rajagopalan N. Physical Stability of Ethyl Diatrizoate Nanocrystalline Suspension in Steam Sterilization. Pharm. Res. 16 (1999) 569-574
-
(1999)
Pharm. Res.
, vol.16
, pp. 569-574
-
-
Na, G.C.1
Stevens, H.J.2
Yuan, B.O.3
Rajagopalan, N.4
-
83
-
-
0032711216
-
An in-vitro assessment of a NanoCrystal™ beclomethasone dipropionate colloidal dispersion via ultrasonic nebulization
-
Ostrander K.D., Bosch H.W., and Bondanza D.M. An in-vitro assessment of a NanoCrystal™ beclomethasone dipropionate colloidal dispersion via ultrasonic nebulization. Eur. J. Pharm. Biopharm. 48 (1999) 207-215
-
(1999)
Eur. J. Pharm. Biopharm.
, vol.48
, pp. 207-215
-
-
Ostrander, K.D.1
Bosch, H.W.2
Bondanza, D.M.3
-
85
-
-
0345593759
-
An investigation into the distribution of lecithins in nanosuspension systems using low frequency dielectric spectroscopy
-
Peters K., Müller R.H., and Craig D.Q.M. An investigation into the distribution of lecithins in nanosuspension systems using low frequency dielectric spectroscopy. Int. J. Pharm. 184 (1999) 53-61
-
(1999)
Int. J. Pharm.
, vol.184
, pp. 53-61
-
-
Peters, K.1
Müller, R.H.2
Craig, D.Q.M.3
-
86
-
-
0033965872
-
Preparation of a clofazimine nanosuspension for intravenous use and evaluation of its therapeutic efficacy in murine Mycobacterium avium infection
-
Peters K., Leitzke S., Diederichs J.E., Borner K., Hahn H., Müller R.H., and Ehlers S. Preparation of a clofazimine nanosuspension for intravenous use and evaluation of its therapeutic efficacy in murine Mycobacterium avium infection. J. Antimicrob. Chemother. 45 (2000) 77-83
-
(2000)
J. Antimicrob. Chemother.
, vol.45
, pp. 77-83
-
-
Peters, K.1
Leitzke, S.2
Diederichs, J.E.3
Borner, K.4
Hahn, H.5
Müller, R.H.6
Ehlers, S.7
-
87
-
-
4544383493
-
Nanosuspensions in drug delivery
-
Rabinow B.E. Nanosuspensions in drug delivery. Nat. Rev. Drug Discov. 3 (2004) 785-796
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 785-796
-
-
Rabinow, B.E.1
-
88
-
-
34648864264
-
Injectable nanoparticles for efficient drug delivery
-
Gupta R.B., and Kompella U.B. (Eds), Taylor & Francis Group, LLC, New York
-
Rabinow B., and Chaubal M.V. Injectable nanoparticles for efficient drug delivery. In: Gupta R.B., and Kompella U.B. (Eds). Nanoparticle Technology for Drug Delivery, Drugs and the Pharmaceutical Sciences vol. 159 (2006), Taylor & Francis Group, LLC, New York 199-229
-
(2006)
Nanoparticle Technology for Drug Delivery, Drugs and the Pharmaceutical Sciences
, vol.159
, pp. 199-229
-
-
Rabinow, B.1
Chaubal, M.V.2
-
89
-
-
34250879747
-
Itraconazole IV nanosuspension enhances efficacy through altered pharmacokinetics in the rat
-
Rabinow B., Kipp J., Papadopoulos P., Wong J., Glosson J., Gass J., Sun C.S., Wielgos T., White R., Cook C., Barker K., and Wood K. Itraconazole IV nanosuspension enhances efficacy through altered pharmacokinetics in the rat. Int. J. Pharm. 339 (2007) 251-260
-
(2007)
Int. J. Pharm.
, vol.339
, pp. 251-260
-
-
Rabinow, B.1
Kipp, J.2
Papadopoulos, P.3
Wong, J.4
Glosson, J.5
Gass, J.6
Sun, C.S.7
Wielgos, T.8
White, R.9
Cook, C.10
Barker, K.11
Wood, K.12
-
90
-
-
1642460578
-
Nanosuspensions as the most promising approach in nanoparticulate drug delivery systems
-
Rao G.C.S., Kumar M.S., Mathivanan N., and Rao M.E.B. Nanosuspensions as the most promising approach in nanoparticulate drug delivery systems. Pharmazie 59 (2004) 5-9
-
(2004)
Pharmazie
, vol.59
, pp. 5-9
-
-
Rao, G.C.S.1
Kumar, M.S.2
Mathivanan, N.3
Rao, M.E.B.4
-
92
-
-
53949092382
-
-
Royal Society and Royal Academy of Engineering, 2004. Nanoscience, and nanotechnology: opportunities and uncertainties. http://www.nanotec.org.uk/finalReport.htm.
-
Royal Society and Royal Academy of Engineering, 2004. Nanoscience, and nanotechnology: opportunities and uncertainties. http://www.nanotec.org.uk/finalReport.htm.
-
-
-
-
93
-
-
0343831483
-
Atovaquone nanosuspensions show excellent therapeutic effect in a new murine model of reactivated toxoplasmosis
-
Schöler N., Krause K., Kayser O., Müller R.H., Borner K., Hahn H., and Liesenfeld O. Atovaquone nanosuspensions show excellent therapeutic effect in a new murine model of reactivated toxoplasmosis. Antimicrob. Agents Chemother. 45 (2001) 1771-1779
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 1771-1779
-
-
Schöler, N.1
Krause, K.2
Kayser, O.3
Müller, R.H.4
Borner, K.5
Hahn, H.6
Liesenfeld, O.7
-
94
-
-
38749130125
-
Method for screening of solid dispersion formulations of low-solubility compounds-miniaturization and automation of solvent casting and dissolution testing
-
Shanbhag A., Rabel S., Nauka E., Casadevall G., Shivanand P., Eichenbaum G., and Mansky P. Method for screening of solid dispersion formulations of low-solubility compounds-miniaturization and automation of solvent casting and dissolution testing. Int. J. Pharm. 351 (2008) 209-218
-
(2008)
Int. J. Pharm.
, vol.351
, pp. 209-218
-
-
Shanbhag, A.1
Rabel, S.2
Nauka, E.3
Casadevall, G.4
Shivanand, P.5
Eichenbaum, G.6
Mansky, P.7
-
95
-
-
34547781194
-
A formulation comparison, using a solution and different nanosuspensions of a poorly soluble compound
-
Sigfridsson K., Forssén S., Holländer P., Skantze U., and de Verdier J. A formulation comparison, using a solution and different nanosuspensions of a poorly soluble compound. Eur. J. Pharm. Biopharm. 67 (2007) 540-547
-
(2007)
Eur. J. Pharm. Biopharm.
, vol.67
, pp. 540-547
-
-
Sigfridsson, K.1
Forssén, S.2
Holländer, P.3
Skantze, U.4
de Verdier, J.5
-
96
-
-
53949120904
-
-
SkyePharma. http://skyepharma.com.
-
SkyePharma. http://skyepharma.com.
-
-
-
-
97
-
-
53949120038
-
-
Symyx. http://www.symyx.com/index.php.
-
Symyx. http://www.symyx.com/index.php.
-
-
-
-
98
-
-
53949117020
-
-
TransForm Pharmaceuticals. http://www.transformpharma.com/.
-
TransForm Pharmaceuticals. http://www.transformpharma.com/.
-
-
-
-
99
-
-
34249039982
-
Characterization of physico-chemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling
-
Van Eerdenbrugh B., Froyen L., Martens J.A., Blaton N., Augustijns P., Brewster M., and Van den Mooter G. Characterization of physico-chemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling. Int. J. Pharm. 338 (2007) 198-206
-
(2007)
Int. J. Pharm.
, vol.338
, pp. 198-206
-
-
Van Eerdenbrugh, B.1
Froyen, L.2
Martens, J.A.3
Blaton, N.4
Augustijns, P.5
Brewster, M.6
Van den Mooter, G.7
-
100
-
-
53949103368
-
-
Van Eerdenbrugh, B., Vermant, J., Martens, J.A., Froyen, L., Van Humbeeck, J., Augustijns, P., Van den Mooter, G., submitted for publication-a. A Screening Study of Surface Stabilization in the Production of Drug Nanocrystals. J. Pharm. Sci.
-
Van Eerdenbrugh, B., Vermant, J., Martens, J.A., Froyen, L., Van Humbeeck, J., Augustijns, P., Van den Mooter, G., submitted for publication-a. A Screening Study of Surface Stabilization in the Production of Drug Nanocrystals. J. Pharm. Sci.
-
-
-
-
101
-
-
53949106114
-
-
Van Eerdenbrugh, B., Froyen, L., Van Humbeeck, J., Martens, J.A., Augustijns, P., Van den Mooter, G., submitted for publication-b. Alternative matrix formers for nanosuspension solidification: dissolution performance and X-ray microanalysis as an evaluation tool for powder dispersion. Eur. J. Pharm. Sci.
-
Van Eerdenbrugh, B., Froyen, L., Van Humbeeck, J., Martens, J.A., Augustijns, P., Van den Mooter, G., submitted for publication-b. Alternative matrix formers for nanosuspension solidification: dissolution performance and X-ray microanalysis as an evaluation tool for powder dispersion. Eur. J. Pharm. Sci.
-
-
-
-
102
-
-
53949092808
-
-
Van Eerdenbrugh, B., Froyen, L., Van Humbeeck, J., Martens, J.A., Augustijns, P., Van den Mooter, G., submitted for publication-c. Scaling down of drug nanosuspension production: process aspects and physico-chemical characterization. AAPS PharmSciTech.
-
Van Eerdenbrugh, B., Froyen, L., Van Humbeeck, J., Martens, J.A., Augustijns, P., Van den Mooter, G., submitted for publication-c. Scaling down of drug nanosuspension production: process aspects and physico-chemical characterization. AAPS PharmSciTech.
-
-
-
-
103
-
-
48849111481
-
Drying of crystalline drug nanosuspensions-the importance of surface hydrophobicity on dissolution behavior upon redispersion
-
Van Eerdenbrugh B., Froyen L., Van Humbeeck J., Martens J.A., Augustijns P., and Van den Mooter G. Drying of crystalline drug nanosuspensions-the importance of surface hydrophobicity on dissolution behavior upon redispersion. Eur. J. Pharm. Sci. 35 (2008) 127-135
-
(2008)
Eur. J. Pharm. Sci.
, vol.35
, pp. 127-135
-
-
Van Eerdenbrugh, B.1
Froyen, L.2
Van Humbeeck, J.3
Martens, J.A.4
Augustijns, P.5
Van den Mooter, G.6
-
104
-
-
53049095815
-
Microcrystalline cellulose, a useful alternative for sucrose as a matrix former during freeze-drying of drug nanosuspensions-a case study with itraconazole
-
Van Eerdenbrugh B., Vercruysse S., Martens J.A., Vermant J., Froyen L., Van Humbeeck G., Van den Mooter L., and Augustijns P. Microcrystalline cellulose, a useful alternative for sucrose as a matrix former during freeze-drying of drug nanosuspensions-a case study with itraconazole. Eur. J. Pharm. Biopharm. 70 (2008) 590-596
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.70
, pp. 590-596
-
-
Van Eerdenbrugh, B.1
Vercruysse, S.2
Martens, J.A.3
Vermant, J.4
Froyen, L.5
Van Humbeeck, G.6
Van den Mooter, L.7
Augustijns, P.8
-
107
-
-
0035927204
-
An oral controlled release matrix pellet formulation containing nanocrystalline ketoprofen
-
Vergote G.J., Vervaet C., Van Driessche I., Hoste S., De Smedt S., Demeester J., Jain R.A., Ruddy S., and Remon J.P. An oral controlled release matrix pellet formulation containing nanocrystalline ketoprofen. Int. J. Pharm. 219 (2001) 81-87
-
(2001)
Int. J. Pharm.
, vol.219
, pp. 81-87
-
-
Vergote, G.J.1
Vervaet, C.2
Van Driessche, I.3
Hoste, S.4
De Smedt, S.5
Demeester, J.6
Jain, R.A.7
Ruddy, S.8
Remon, J.P.9
-
108
-
-
0037142222
-
In vivo evaluation of matrix pellets containing nanocrystalline ketoprofen
-
Vergote G.J., Vervaet C., Van Driessche I., Hoste S., De Smedt S., Demeester J., Jain R.A., Ruddy S., and Remon J.P. In vivo evaluation of matrix pellets containing nanocrystalline ketoprofen. Int. J. Pharm. 240 (2002) 79-84
-
(2002)
Int. J. Pharm.
, vol.240
, pp. 79-84
-
-
Vergote, G.J.1
Vervaet, C.2
Van Driessche, I.3
Hoste, S.4
De Smedt, S.5
Demeester, J.6
Jain, R.A.7
Ruddy, S.8
Remon, J.P.9
-
110
-
-
34547259640
-
Pharmacokinetic evaluation of a 1,3-dicyclohexylurea nanosuspension formulation to support early efficacy assessment
-
Wahlstrom J.L., Chiang P.C., Ghosh S., Warren C.J., Wene S.P., Albin L.A., Smith M.E., and Roberds S.L. Pharmacokinetic evaluation of a 1,3-dicyclohexylurea nanosuspension formulation to support early efficacy assessment. Nanoscale Res. Lett. 2 (2007) 291-296
-
(2007)
Nanoscale Res. Lett.
, vol.2
, pp. 291-296
-
-
Wahlstrom, J.L.1
Chiang, P.C.2
Ghosh, S.3
Warren, C.J.4
Wene, S.P.5
Albin, L.A.6
Smith, M.E.7
Roberds, S.L.8
-
111
-
-
0030614519
-
Nebulization of NanoCrystals™: production of a respirable solid-in-liquid-in-air colloidal dispersion
-
Wiedmann T.S., DeCastro L., and Wood R.W. Nebulization of NanoCrystals™: production of a respirable solid-in-liquid-in-air colloidal dispersion. Pharm. Res. 14 (1997) 112-116
-
(1997)
Pharm. Res.
, vol.14
, pp. 112-116
-
-
Wiedmann, T.S.1
DeCastro, L.2
Wood, R.W.3
-
112
-
-
42649115104
-
Suspensions for intravenous (IV) injection: a review of development, preclinical and clinical aspects
-
Wong J., Brugger A., Khare A., Chaubal M., Papadopoulos P., Rabinow B., Kipp J., and Ning J. Suspensions for intravenous (IV) injection: a review of development, preclinical and clinical aspects. Adv. Drug Deliv. Rev. 60 (2008) 939-954
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 939-954
-
-
Wong, J.1
Brugger, A.2
Khare, A.3
Chaubal, M.4
Papadopoulos, P.5
Rabinow, B.6
Kipp, J.7
Ning, J.8
-
113
-
-
20844446627
-
The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: a Beagle dog model predicts improved bioavailability and diminished food effect on absorption in human
-
Wu Y., Loper A., Landis E., Hettrick L., Novak L., Lynn K., Chen C., Thompson K., Higgins R., Batra U., Shelukar S., Kwei G., and Storey D. The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: a Beagle dog model predicts improved bioavailability and diminished food effect on absorption in human. Int. J. Pharm. 285 (2004) 135-146
-
(2004)
Int. J. Pharm.
, vol.285
, pp. 135-146
-
-
Wu, Y.1
Loper, A.2
Landis, E.3
Hettrick, L.4
Novak, L.5
Lynn, K.6
Chen, C.7
Thompson, K.8
Higgins, R.9
Batra, U.10
Shelukar, S.11
Kwei, G.12
Storey, D.13
-
114
-
-
38349162256
-
Preparation and characterization of intravenously injectable nimodipine nanosuspension
-
Xiong R., Lu W., Li J., Wang P., Xu R., and Chen T. Preparation and characterization of intravenously injectable nimodipine nanosuspension. Int. J. Pharm. 350 (2008) 338-343
-
(2008)
Int. J. Pharm.
, vol.350
, pp. 338-343
-
-
Xiong, R.1
Lu, W.2
Li, J.3
Wang, P.4
Xu, R.5
Chen, T.6
-
115
-
-
34249323769
-
Preparation of azithromycin nanosuspensions by high pressure homogenization and its physicochemical characteristics studies
-
Zhang D., Tan T., Gao L., Zhao W., and Wang P. Preparation of azithromycin nanosuspensions by high pressure homogenization and its physicochemical characteristics studies. Drug Dev. Ind. Pharm. 33 (2007) 569-575
-
(2007)
Drug Dev. Ind. Pharm.
, vol.33
, pp. 569-575
-
-
Zhang, D.1
Tan, T.2
Gao, L.3
Zhao, W.4
Wang, P.5
-
116
-
-
0030695406
-
Sterile filtration of NanoCrystal™ drug formulations
-
Zheng J.Y., and Bosch H.W. Sterile filtration of NanoCrystal™ drug formulations. Drug Dev. Ind. Pharm. 23 (1997) 1087-1093
-
(1997)
Drug Dev. Ind. Pharm.
, vol.23
, pp. 1087-1093
-
-
Zheng, J.Y.1
Bosch, H.W.2
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