메뉴 건너뛰기




Volumn 207, Issue , 2012, Pages 361-383

Heparin mimetics

Author keywords

Glycosaminoglycan; GMI 1070; Heparin; Heparin mimetics; PI 88; RGTAs

Indexed keywords

ALGINIC ACID; APROSULATE; CACIPLIQ20; CD31 ANTIGEN; CELLULOSE; CELLULOSE SULFATE; CHITIN; DEXTRAN; EP 217609; FONDAPARINUX; GALACTAN; GMI 1070; HEPARIN; HEPARIN DERIVATIVE; HEPARIN MIMETIC; HIRUDOID; INULIN; OTR 4120; PEGAPTANIB; PENTOSAN POLYSULFATE; PI 88; PRO 2000; RG 1192; RG 1503; RGTA 11; SUCRALFATE; SUCROSOFATE; SURAMIN; THROMBIN INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VIVAGEL;

EID: 84861898052     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/978-3-642-23056-1_16     Document Type: Article
Times cited : (26)

References (110)
  • 1
    • 37149049377 scopus 로고    scopus 로고
    • Herpes simplex virus type 2 glycoprotein G is targeted by the sulfated oligo- and polysaccharide inhibitors of virus attachment to cells
    • Adamiak B, Ekblad M, Bergstr€om T, Ferro V, Trybala E (2007) Herpes simplex virus type 2 glycoprotein G is targeted by the sulfated oligo- and polysaccharide inhibitors of virus attachment to cells. J Virol 81:13424-13434
    • (2007) J. Virol. , vol.81 , pp. 13424-13434
    • Adamiak, B.1    Ekblad, M.2    Bergstrom, T.3    Ferro, V.4    Trybala, E.5
  • 2
    • 33746914763 scopus 로고    scopus 로고
    • Inhibition of Plasmodium falciparum growth in vitro and adhesion to chondroitin-4-sulfate by the heparan sulfate mimetic PI-88 and other sulfated oligosaccharides
    • Adams Y, Freeman C, Schwartz-Albiez R, Ferro V, Parish CR, Andrews KT (2006) Inhibition of Plasmodium falciparum growth in vitro and adhesion to chondroitin-4-sulfate by the heparan sulfate mimetic PI-88 and other sulfated oligosaccharides . Antimicrob Agents Chemother 50:2850-2852
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 2850-2852
    • Adams, Y.1    Freeman, C.2    Schwartz-Albiez, R.3    Ferro, V.4    Parish, C.R.5    Andrews, K.T.6
  • 3
    • 84861857841 scopus 로고    scopus 로고
    • Adverse effects of heparin
    • Lever R, Mulloy B, Page CP eds Springer, Heidelberg
    • Alban S (2011) Adverse effects of heparin. In: Lever R, Mulloy B, Page CP (eds) Heparin - a century of progress. Springer, Heidelberg
    • (2011) Heparin - A Century of Progress
    • Alban, S.1
  • 4
    • 9444228224 scopus 로고    scopus 로고
    • Structurally different RGTAs modulate collagen-type expression by cultured aortic smooth muscle cells via different pathways involving fibroblast growth factor-2 or transforming growth factor-b1
    • Alexakis C, Mestries P, Garcia S, Petit E, Barbier V, Papy-Garcia D, Sagot M-A, Barritault D, Caruelle JP, Kern P (2004) Structurally different RGTAs modulate collagen-type expression by cultured aortic smooth muscle cells via different pathways involving fibroblast growth factor-2 or transforming growth factor-b1 . FASEB J 18:1147-1159
    • (2004) FASEB J. , vol.18 , pp. 1147-1159
    • Alexakis, C.1    Mestries, P.2    Garcia, S.3    Petit, E.4    Barbier, V.5    Papy-Garcia, D.6    Sagot, M.-A.7    Barritault, D.8    Caruelle, J.P.9    Kern, P.10
  • 7
    • 0032546514 scopus 로고    scopus 로고
    • In vitro evaluation of synthetic heparin-like conjugates comprising different thrombin binding domains
    • Basten JE, Dreef-Tromp CM, de Wijs B, van Boeckel CA (1998) In vitro evaluation of synthetic heparin-like conjugates comprising different thrombin binding domains. Bioorg Med Chem Lett 8:1201-1206
    • (1998) Bioorg. Med. Chem. Lett. , vol.8 , pp. 1201-1206
    • Basten, J.E.1    Dreef-Tromp, C.M.2    De Wijs, B.3    Van Boeckel, C.A.4
  • 8
    • 0000602173 scopus 로고    scopus 로고
    • Concepts for preparation of novel regioselective modified cellulose derivatives sulfated, aminated, carboxylated and acetylated for hemocompatible ultrathin coatings on biomaterials
    • Baumann H, Richter A, Klemm D, Faust V (2000) Concepts for preparation of novel regioselective modified cellulose derivatives sulfated, aminated, carboxylated and acetylated for hemocompatible ultrathin coatings on biomaterials. Macromol Chem Phys 201:1950-1962
    • (2000) Macromol Chem. Phys. , vol.201 , pp. 1950-1962
    • Baumann, H.1    Richter, A.2    Klemm, D.3    Faust, V.4
  • 9
    • 33748233635 scopus 로고
    • The unique antithrombin III binding domain of heparin: A lead to new synthetic antithrombotics
    • van Boeckel CAA, Petitou M (1993) The unique antithrombin III binding domain of heparin: A lead to new synthetic antithrombotics. Angew Chem Int Ed Engl 32:1671-1690
    • (1993) Angew Chem. Int. Ed. Engl. , vol.32 , pp. 1671-1690
    • Van Boeckel, C.A.A.1    Petitou, M.2
  • 10
    • 34447277610 scopus 로고    scopus 로고
    • Heparin-mimicking sulfonic acid polymers as multitarget inhibitors of human immunodeficiency virus type 1 Tat and gp120 proteins
    • Bugatti A, Urbinati C, Ravelli C, De Clercq E, Liekens S, Rusnati M (2007) Heparin-mimicking sulfonic acid polymers as multitarget inhibitors of human immunodeficiency virus type 1 Tat and gp120 proteins. Antimicrob Agents Chemother 51:2337-2345
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 2337-2345
    • Bugatti, A.1    Urbinati, C.2    Ravelli, C.3    De Clercq, E.4    Liekens, S.5    Rusnati, M.6
  • 12
    • 0037047779 scopus 로고    scopus 로고
    • LaPSvS1, a (1- > 3)-betagalactan sulfate and its effect on angiogenesis in vivo and in vitro
    • Burgermeister J, Paper DH, Vogl H, Linhardt RJ, Franz G (2002) LaPSvS1, a (1- > 3)-betagalactan sulfate and its effect on angiogenesis in vivo and in vitro. Carbohydr Res 337: 1459-1466
    • (2002) Carbohydr. Res. , vol.337 , pp. 1459-1466
    • Burgermeister, J.1    Paper, D.H.2    Vogl, H.3    Linhardt, R.J.4    Franz, G.5
  • 18
    • 36849038980 scopus 로고    scopus 로고
    • Effects on coagulation of a synthetic heparin mimetic given intraperitoneally or orally
    • Charef S, Petit E, Barritault D, Courty J, Caruelle JP (2007) Effects on coagulation of a synthetic heparin mimetic given intraperitoneally or orally. J Biomed Mater Res 83A:1024-1031
    • (2007) J. Biomed. Mater Res. , vol.83 , pp. 1024-1031
    • Charef, S.1    Petit, E.2    Barritault, D.3    Courty, J.4    Caruelle, J.P.5
  • 23
    • 0141992781 scopus 로고    scopus 로고
    • Probing the interactions of phosphosulfomannans with angiogenic growth factors by surface plasmon resonance
    • Cochran S, Li C, Fairweather JK, Kett WC, Coombe DR, Ferro V (2003) Probing the interactions of phosphosulfomannans with angiogenic growth factors by surface plasmon resonance. J Med Chem 46:4601-4608
    • (2003) J. Med. Chem. , vol.46 , pp. 4601-4608
    • Cochran, S.1    Li, C.2    Fairweather, J.K.3    Kett, W.C.4    Coombe, D.R.5    Ferro, V.6
  • 24
  • 25
    • 67649744221 scopus 로고    scopus 로고
    • Antiviral drug discovery: Ten more compounds, and ten more stories (part B
    • De Clercq E (2009a) Antiviral drug discovery: ten more compounds, and ten more stories (part B). Med Res Rev 29:571-610
    • (2009) Med. Res. Rev. , vol.29 , pp. 571-610
    • De Clercq, E.1
  • 26
    • 78650003024 scopus 로고    scopus 로고
    • The next ten stories on antiviral drug discovery (part E): Advents, advances, and adventures
    • 10.1002/med.20179
    • De Clercq E (2009b) The next ten stories on antiviral drug discovery (part E): Advents, advances, and adventures. Med Res Rev. doi:10.1002/med.20179
    • (2009) Med. Res. Rev.
    • De Clercq, E.1
  • 30
    • 68249116079 scopus 로고    scopus 로고
    • From carbohydrate leads to glycomimetic drugs
    • Ernst B, Magnani JL (2009) From carbohydrate leads to glycomimetic drugs. Nat Rev Drug Discov 8:661-677
    • (2009) Nat. Rev. Drug Discov. , vol.8 , pp. 661-677
    • Ernst, B.1    Magnani, J.L.2
  • 31
    • 33646915292 scopus 로고    scopus 로고
    • Semi-synthetic heparin derivatives: Chemical modifications of heparin beyond chain length, sulfate substitution pattern and N-sulfo/N-acetyl groups
    • Fernandez C, Hattan CM, Kerns RJ (2006) Semi-synthetic heparin derivatives: Chemical modifications of heparin beyond chain length, sulfate substitution pattern and N-sulfo/N-acetyl groups. Carbohydr Res 341:1253-1265
    • (2006) Carbohydr. Res. , vol.341 , pp. 1253-1265
    • Fernandez, C.1    Hattan, C.M.2    Kerns, R.J.3
  • 32
    • 15744392518 scopus 로고    scopus 로고
    • Use of sulfated linked cyclitols as heparan sulfate mimetics to probe the heparin/heparan sulfate binding specificity of proteins
    • Freeman C, Liu L, Banwell MG, Brown KJ, Bezos A, Ferro V, Parish CR (2005) Use of sulfated linked cyclitols as heparan sulfate mimetics to probe the heparin/heparan sulfate binding specificity of proteins. J Biol Chem 280:8842-8849
    • (2005) J. Biol. Chem. , vol.280 , pp. 8842-8849
    • Freeman, C.1    Liu, L.2    Banwell, M.G.3    Brown, K.J.4    Bezos, A.5    Ferro, V.6    Parish, C.R.7
  • 33
    • 43549093249 scopus 로고    scopus 로고
    • The effect of sulfation of alginate hydrogels on the specific binding and controlled release of heparin-binding proteins
    • Freeman I, Kedem A, Cohen S (2008) The effect of sulfation of alginate hydrogels on the specific binding and controlled release of heparin-binding proteins. Biomaterials 29:3260-3268
    • (2008) Biomaterials , vol.29 , pp. 3260-3268
    • Freeman, I.1    Kedem, A.2    Cohen, S.3
  • 34
    • 33745965444 scopus 로고    scopus 로고
    • The influence of various structural parameters of semisynthetic sulfated polysaccharides on the Pselectin inhibitory capacity
    • Fritzsche J, Alban S, Ludwig RJ, Rubant S, Boehncke WH, Schumacher G, Bendas G (2006) The influence of various structural parameters of semisynthetic sulfated polysaccharides on the Pselectin inhibitory capacity. Biochem Pharmacol 72:474-485
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 474-485
    • Fritzsche, J.1    Alban, S.2    Ludwig, R.J.3    Rubant, S.4    Boehncke, W.H.5    Schumacher, G.6    Bendas, G.7
  • 37
    • 42449087252 scopus 로고    scopus 로고
    • Platelet endothelial cell adhesion molecule-1 (PECAM-1) and its interactions with glycosaminoglycans I molecular modelling studies
    • Gandhi NS, Coombe DR, Mancera RL (2008) Platelet endothelial cell adhesion molecule-1 (PECAM-1) and its interactions with glycosaminoglycans I. Molecular modelling studies. Biochemistry 47:4851-4862
    • (2008) Biochemistry , vol.47 , pp. 4851-4862
    • Gandhi, N.S.1    Coombe, D.R.2    Mancera, R.L.3
  • 38
    • 33750030783 scopus 로고    scopus 로고
    • Conformational transitions induced in heparin octasaccharides by binding with antithrombin III
    • Guerrini M, Guglieri S, Beccati D, Torri G, Viskov C, Mourier P (2006) Conformational transitions induced in heparin octasaccharides by binding with antithrombin III. Biochem J 399:191-198
    • (2006) Biochem. J. , vol.399 , pp. 191-198
    • Guerrini, M.1    Guglieri, S.2    Beccati, D.3    Torri, G.4    Viskov, C.5    Mourier, P.6
  • 39
    • 0033008853 scopus 로고    scopus 로고
    • Heparinoids: Structure, biological activities and therapeutic applications
    • Gunay NS, Linhardt RJ (1999) Heparinoids: structure, biological activities and therapeutic applications. Planta Med 65:301-306
    • (1999) Planta Med. , vol.65 , pp. 301-306
    • Gunay, N.S.1    Linhardt, R.J.2
  • 41
    • 37449034698 scopus 로고    scopus 로고
    • Chemistry and biology of heparin mimetics that bind to fibroblast growth factors
    • Hassan HH (2007) Chemistry and biology of heparin mimetics that bind to fibroblast growth factors. Mini Rev Med Chem 7:1206-1235
    • (2007) Mini. Rev. Med. Chem. , vol.7 , pp. 1206-1235
    • Hassan, H.H.1
  • 42
    • 68949090333 scopus 로고    scopus 로고
    • Interaction of antithrombin with sulfated, low molecular weight lignins: Opportunities for potent, selective modulation of antithrombin function
    • Henry BL, Connell J, Liang A, Krishnasamy C, Desai UR (2009) Interaction of antithrombin with sulfated, low molecular weight lignins: Opportunities for potent, selective modulation of antithrombin function. J Biol Chem 284:20897-20908
    • (2009) J. Biol. Chem. , vol.284 , pp. 20897-20908
    • Henry, B.L.1    Connell, J.2    Liang, A.3    Krishnasamy, C.4    Desai, U.R.5
  • 43
    • 4644308426 scopus 로고    scopus 로고
    • Heparin and low-molecular-weight heparin: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • Hirsh J, Raschke R (2004) Heparin and low-molecular-weight heparin: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 126:188S-203S
    • (2004) Chest , vol.126
    • Hirsh, J.1    Raschke, R.2
  • 45
    • 0028788101 scopus 로고
    • Characterisation of a laminarin sulphate which inhibits basic fibroblast growth factor binding and endothelial cell proliferation
    • Pt 11
    • Hoffman R, Paper DH, Donaldson J, Alban S, Franz G (1995) Characterisation of a laminarin sulphate which inhibits basic fibroblast growth factor binding and endothelial cell proliferation. J Cell Sci 108(Pt 11):3591-3598
    • (1995) J. Cell Sci. , vol.108 , pp. 3591-3598
    • Hoffman, R.1    Paper, D.H.2    Donaldson, J.3    Alban, S.4    Franz, G.5
  • 46
    • 4644279797 scopus 로고    scopus 로고
    • Facile synthesis of chain-end functionalized glycopolymers for site-specific bioconjugation
    • Hou S, Sun XL, Dong CM, Chaikof EL (2004) Facile synthesis of chain-end functionalized glycopolymers for site-specific bioconjugation. Bioconjug Chem 15:954-959
    • (2004) Bioconjug. Chem. , vol.15 , pp. 954-959
    • Hou, S.1    Sun, X.L.2    Dong, C.M.3    Chaikof, E.L.4
  • 47
    • 8844226873 scopus 로고    scopus 로고
    • Chemistry, biochemistry, and pharmaceutical potentials of glycosaminoglycans and related saccharides
    • Wong C ed Wiley, Weinheim
    • Islam T, Linhardt R (2003) Chemistry, biochemistry, and pharmaceutical potentials of glycosaminoglycans and related saccharides. In: Wong C (ed) Carbohydrate-based drug discovery. Wiley, Weinheim, pp 407-427
    • (2003) Carbohydrate-Based Drug Discovery , pp. 407-427
    • Islam, T.1    Linhardt, R.2
  • 50
    • 0035864893 scopus 로고    scopus 로고
    • Sulfated beta-(1- > 4)-galacto-oligosaccharides and their effect on angiogenesis
    • Kasbauer CW, Paper DH, Franz G (2001) Sulfated beta-(1- > 4)-galacto-oligosaccharides and their effect on angiogenesis. Carbohydr Res 330:427-430
    • (2001) Carbohydr. Res. , vol.330 , pp. 427-430
    • Kasbauer, C.W.1    Paper, D.H.2    Franz, G.3
  • 51
    • 0033050063 scopus 로고    scopus 로고
    • Synthesis of sulfated oligosaccharide glycosides having high anti-HIV activity and the relationship between activity and chemical structure
    • Katsuraya K, Nakashima H, Yamamoto N, Uryu T (1999) Synthesis of sulfated oligosaccharide glycosides having high anti-HIV activity and the relationship between activity and chemical structure. Carbohydr Res 315:234-242
    • (1999) Carbohydr. Res. , vol.315 , pp. 234-242
    • Katsuraya, K.1    Nakashima, H.2    Yamamoto, N.3    Uryu, T.4
  • 55
    • 1642370756 scopus 로고    scopus 로고
    • Phosphomannopentaose sulfate (PI-88): Heparan sulfate mimetic with clinical potential in multiple vascular pathologies
    • Khachigian LM, Parish CR (2004) Phosphomannopentaose sulfate (PI-88): heparan sulfate mimetic with clinical potential in multiple vascular pathologies. Cardiovasc Drug Rev 22:1-6
    • (2004) Cardiovasc. Drug Rev. , vol.22 , pp. 1-6
    • Khachigian, L.M.1    Parish, C.R.2
  • 56
    • 77953974391 scopus 로고    scopus 로고
    • Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer
    • doi:10.1093/annonc/mdp524
    • Khasraw M, Pavlakis N, McCowatt S, Underhill C, Begbie S, de Souza P, Boyce A, Parnis F, Lim V, Harvie R, Marx G (2009) Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer. Ann Oncol. doi:10.1093/annonc/ mdp524
    • (2009) Ann Oncol.
    • Khasraw, M.1    Pavlakis, N.2    McCowatt, S.3    Underhill, C.4    Begbie, S.5    De Souza, P.6    Boyce, A.7    Parnis, F.8    Lim, V.9    Harvie, R.10    Marx, G.11
  • 57
    • 35248870571 scopus 로고    scopus 로고
    • A newly developed oral heparin derivative for deep vein thrombosis: Non-Human primate study
    • Kim SK, Lee DY, Kim CY, Nam JH, Moon HT, Byun Y (2007) A newly developed oral heparin derivative for deep vein thrombosis: non-human primate study. J Control Release 123:155-163
    • (2007) J. Control. Release , vol.123 , pp. 155-163
    • Kim, S.K.1    Lee, D.Y.2    Kim, C.Y.3    Nam, J.H.4    Moon, H.T.5    Byun, Y.6
  • 61
    • 77949877103 scopus 로고    scopus 로고
    • Inhibitors of slit protein interactions with the heparan sulfate proteoglycan glypican-1: Potential agents for the treatment of spinal cord injury
    • 10.1111/j.1440-1681.2009.05318.x
    • Lau E, Margolis RU (2009) Inhibitors of slit protein interactions with the heparan sulfate proteoglycan glypican-1: potential agents for the treatment of spinal cord injury. Clin Exp Pharmacol Physiol. doi:10.1111/j.1440-1681.2009. 05318.x
    • (2009) Clin. Exp. Pharmacol. Physiol.
    • Lau, E.1    Margolis, R.U.2
  • 62
    • 29044443281 scopus 로고    scopus 로고
    • Antiviral effect of the heparan sulfate mimetic, PI-88, against dengue and encephalitic flaviviruses
    • Lee E, Pavy M, Young N, Freeman C, Lobigs M (2006) Antiviral effect of the heparan sulfate mimetic, PI-88, against dengue and encephalitic flaviviruses. Antiviral Res 69:31-38
    • (2006) Antiviral Res. , vol.69 , pp. 31-38
    • Lee, E.1    Pavy, M.2    Young, N.3    Freeman, C.4    Lobigs, M.5
  • 66
    • 0032810028 scopus 로고    scopus 로고
    • Carboxymethyl benzylamide sulfonate dextrans (CMDBS), a family of biospecific polymers endowed with numerous biological properties: A review
    • Logeart-Avramoglou D, Jozefonvicz J (1999) Carboxymethyl benzylamide sulfonate dextrans (CMDBS), a family of biospecific polymers endowed with numerous biological properties: A review. J Biomed Mater Res 48:578-590
    • (1999) J. Biomed. Mater Res. , vol.48 , pp. 578-590
    • Logeart-Avramoglou, D.1    Jozefonvicz, J.2
  • 67
    • 34249774286 scopus 로고    scopus 로고
    • Emerging role of anticoagulants and fibrinolytics in the treatment of acute respiratory syndrome
    • MacLaren R, Stringer KA (2007) Emerging role of anticoagulants and fibrinolytics in the treatment of acute respiratory syndrome. Pharmacotherapy 27:860-873
    • (2007) Pharmacotherapy , vol.27 , pp. 860-873
    • MacLaren, R.1    Stringer, K.A.2
  • 68
    • 2542443669 scopus 로고    scopus 로고
    • The discovery, biology, and drug development of sialyl Lea and sialyl Lex
    • Magnani JL (2004) The discovery, biology, and drug development of sialyl Lea and sialyl Lex. Arch Biochem Biophys 426:122-131
    • (2004) Arch. Biochem. Biophys , vol.426 , pp. 122-131
    • Magnani, J.L.1
  • 72
    • 33644804663 scopus 로고    scopus 로고
    • Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor
    • Maynard HD, Hubbell JA (2005) Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor . Acta Biomater 1:451-459
    • (2005) Acta. Biomater. , vol.1 , pp. 451-459
    • Maynard, H.D.1    Hubbell, J.A.2
  • 73
    • 13944281986 scopus 로고    scopus 로고
    • Antithrombin activation by nonsulfated, non-Polysaccharide organic polymer
    • Monien BH, Desai UR (2005) Antithrombin activation by nonsulfated, non-polysaccharide organic polymer. J Med Chem 48:1269-1273
    • (2005) J. Med. Chem. , vol.48 , pp. 1269-1273
    • Monien, B.H.1    Desai, U.R.2
  • 74
    • 33748495334 scopus 로고    scopus 로고
    • Synthetic oligosaccharide stimulates and stabilizes angiogenesis: Structure-function relationships and potential mechanisms
    • Mousa SA, Feng X, Xie J, Du Y, Hua Y, He H, O'Connor L, Linhardt RJ (2006) Synthetic oligosaccharide stimulates and stabilizes angiogenesis: structure-function relationships and potential mechanisms. J Cardiovasc Pharmacol 48:6-13
    • (2006) J. Cardiovasc. Pharmacol. , vol.48 , pp. 6-13
    • Mousa, S.A.1    Feng, X.2    Xie, J.3    Du, Y.4    Hua, Y.5    He, H.6    O'Connor, L.7    Linhardt, R.J.8
  • 75
    • 33947397199 scopus 로고    scopus 로고
    • Aurintricarboxylic acid inhibits the early stage of vaccinia virus replication by targeting both cellular and viral factors
    • Myskiw C, Deschambault Y, Jefferies K, He R, Cao J (2007) Aurintricarboxylic acid inhibits the early stage of vaccinia virus replication by targeting both cellular and viral factors. J Virol 81:3027-3032
    • (2007) J. Virol. , vol.81 , pp. 3027-3032
    • Myskiw, C.1    Deschambault, Y.2    Jefferies, K.3    He, R.4    Cao, J.5
  • 79
    • 71149085990 scopus 로고    scopus 로고
    • Microbicides Development Programme: Design of a phase iii trial to measure the efficacy of the vaginal microbicide pro 2000/5 for hiv prevention
    • Nunn A, McCormack S, Crook AM, Pool R, Rutterford C, Hayes R (2009) Microbicides Development Programme: design of a phase III trial to measure the efficacy of the vaginal microbicide PRO 2000/5 for HIV prevention. Trials 10:99
    • (2009) Trials , vol.10 , pp. 99
    • Nunn, A.1    McCormack, S.2    Crook, A.M.3    Pool, R.4    Rutterford, C.5    Hayes, R.6
  • 80
    • 77649116837 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics of spl7013 gel (vivagel(r)): A dose ranging, phase i study
    • 10.1097/OLQ.0b013e3181bc0aac
    • O'Loughlin J, Millwood IY, McDonald HM, Price CF, Kaldor JM, Paull JR (2009) Safety, tolerability, and pharmacokinetics of SPL7013 Gel (VivaGel(R)): A dose ranging, phase I study. Sex Transm Dis. doi:10.1097/OLQ.0b013e3181bc0aac
    • (2009) Sex Transm. Dis.
    • O'Loughlin, J.1    Millwood, I.Y.2    McDonald, H.M.3    Price, C.F.4    Kaldor, J.M.5    Paull, J.R.6
  • 86
    • 0031001403 scopus 로고    scopus 로고
    • Epithelial coating techniques in the treatment of interstitial cystitis
    • Parsons CL (1997) Epithelial coating techniques in the treatment of interstitial cystitis. Urology 49:100-104
    • (1997) Urology , vol.49 , pp. 100-104
    • Parsons, C.L.1
  • 90
  • 91
    • 34548040716 scopus 로고    scopus 로고
    • Rapid and efficient microwave-assisted synthesis of highly sulfated organic scaffolds
    • Raghuraman A, Riaz M, Hindle M, Desai UR (2007) Rapid and efficient microwave-assisted synthesis of highly sulfated organic scaffolds. Tetrahedron Lett 48:6754-6758
    • (2007) Tetrahedron. Lett. , vol.48 , pp. 6754-6758
    • Raghuraman, A.1    Riaz, M.2    Hindle, M.3    Desai, U.R.4
  • 93
    • 10844229062 scopus 로고    scopus 로고
    • Design and synthesis of dimeric heparinoid mimetics
    • Rele SM, Iyer SS, Baskaran S, Chaikof EL (2004) Design and synthesis of dimeric heparinoid mimetics. J Org Chem 69:9159-9170
    • (2004) J Org Chem , vol.69 , pp. 9159-9170
    • Rele, S.M.1    Iyer, S.S.2    Baskaran, S.3    Chaikof, E.L.4
  • 94
    • 31544464118 scopus 로고    scopus 로고
    • Arginine- And lysine-specific polymers for protein recognition and immobilization
    • Renner C, Piehler J, Schrader T (2006) Arginine- and lysine-specific polymers for protein recognition and immobilization. J Am Chem Soc 128:620-628
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 620-628
    • Renner, C.1    Piehler, J.2    Schrader, T.3
  • 95
    • 4444362263 scopus 로고    scopus 로고
    • Glycosaminoglycans and the regulation of allergic inflammation
    • Rose MJ, Page C (2004) Glycosaminoglycans and the regulation of allergic inflammation. Curr Drug Targets Inflamm Allergy 3:221-225
    • (2004) Curr. Drug Targets. Inflamm. Allergy , vol.3 , pp. 221-225
    • Rose, M.J.1    Page, C.2
  • 98
    • 58849110356 scopus 로고    scopus 로고
    • Microbial polysaccharides and their derivatives as current and prospective pharmaceuticals
    • Smelcerovic A, Knezevic-Jugovic Z, Petronijevic Z (2008) Microbial polysaccharides and their derivatives as current and prospective pharmaceuticals. Curr Pharm Des 14:3168-3195
    • (2008) Curr. Pharm. Des. , vol.14 , pp. 3168-3195
    • Smelcerovic, A.1    Knezevic-Jugovic, Z.2    Petronijevic, Z.3
  • 99
    • 0035097297 scopus 로고    scopus 로고
    • Preparation and inhibitory activity on hyaluronidase of fully O-sulfated hyaluro-oligosaccharides
    • Suzuki A, Toyoda H, Toida T, Imanari T (2001) Preparation and inhibitory activity on hyaluronidase of fully O-sulfated hyaluro-oligosaccharides. Glycobiology 11:57-64
    • (2001) Glycobiology , vol.11 , pp. 57-64
    • Suzuki, A.1    Toyoda, H.2    Toida, T.3    Imanari, T.4
  • 101
    • 56349167518 scopus 로고    scopus 로고
    • Polyanionic drugs and viral oncogenesis: A novel approach to control infection, tumor-Associated inflammation and angiogenesis
    • Urbinati C, Chiodelli P, Rusnati M (2008) Polyanionic drugs and viral oncogenesis: A novel approach to control infection, tumor-associated inflammation and angiogenesis. Molecules 13:2758-2785
    • (2008) Molecules , vol.13 , pp. 2758-2785
    • Urbinati, C.1    Chiodelli, P.2    Rusnati, M.3
  • 103
    • 51649102765 scopus 로고    scopus 로고
    • Topically applied heparins for the treatment of vascular disorders: A comprehensive review
    • Vecchio C, Frisinghelli A (2008) Topically applied heparins for the treatment of vascular disorders: A comprehensive review. Clin Drug Investig 28:603-614
    • (2008) Clin. Drug Investig. , vol.28 , pp. 603-614
    • Vecchio, C.1    Frisinghelli, A.2
  • 105
    • 0035880995 scopus 로고    scopus 로고
    • Characterisation of the anticoagulant properties of a range of structurally diverse sulfated oligosaccharides
    • Wall D, Douglas S, Ferro V, Cowden W, Parish C (2001) Characterisation of the anticoagulant properties of a range of structurally diverse sulfated oligosaccharides. Thromb Res 103: 325-335
    • (2001) Thromb. Res. , vol.103 , pp. 325-335
    • Wall, D.1    Douglas, S.2    Ferro, V.3    Cowden, W.4    Parish, C.5
  • 106
    • 70349776204 scopus 로고    scopus 로고
    • Physicochemical properties and antitumor activities for sulfated derivatives of lentinan
    • Wang X, Zhang L (2009) Physicochemical properties and antitumor activities for sulfated derivatives of lentinan. Carbohydr Res 344:2209-2216
    • (2009) Carbohydr. Res. , vol.344 , pp. 2209-2216
    • Wang, X.1    Zhang, L.2
  • 110
    • 33749008541 scopus 로고    scopus 로고
    • Oligomannurarate sulfate, a novel heparanase inhibitor simultaneously targeting basic fibroblast growth factor, combats tumor angiogenesis and metastasis
    • Zhao H, Liu H, Chen Y, Xin X, Li J, Hou Y, Zhang Z, Zhang X, Xie C, Geng M, Ding J (2006) Oligomannurarate sulfate, a novel heparanase inhibitor simultaneously targeting basic fibroblast growth factor, combats tumor angiogenesis and metastasis. Cancer Res 66:8779-8787
    • (2006) Cancer Res. , vol.66 , pp. 8779-8787
    • Zhao, H.1    Liu, H.2    Chen, Y.3    Xin, X.4    Li, J.5    Hou, Y.6    Zhang, Z.7    Zhang, X.8    Xie, C.9    Geng, M.10    Ding, J.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.