Semi-synthetic heparin derivatives: chemical modifications of heparin beyond chain length, sulfate substitution pattern and N-sulfo/N-acetyl groups

Carbohydrate Research

Volumn 341, Issue 10, 2006, Pages 1253-1265

  Fernández, Cristina ^a   Hattan, Christopher M ^a   Kerns, Robert J ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Glycosaminoglycans; Heparin; Heparin analogs; Heparinoids; Semi synthesis

Indexed keywords

BIOSYNTHESIS; COAGULATION; NEGATIVE IONS; POLYSACCHARIDES; POSITIVE IONS; PROTEINS; REDUCTION;

GLYCOSAMINOGLYCANS; HEPARIN; HEPARIN ANALOGS; HEPARINOIDS; SEMI-SYNTHESIS;

DERIVATIVES;

ACETIC ACID DERIVATIVE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTICOAGULANT AGENT; ANTIINFECTIVE AGENT; ANTILIPEMIC AGENT; ANTINEOPLASTIC AGENT; ANTITHROMBIN; CARBOXYL GROUP; DIMETHYL SULFOXIDE; FONDAPARINUX; GLUCOSAMINE DERIVATIVE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HEPARIN BINDING PROTEIN; HEPARIN DERIVATIVE; IDRAPARINUX; METAL CHELATE; PENTETIC ACID; POLYSACCHARIDE; SERINE PROTEINASE INHIBITOR; SULFATE; SULFUR DERIVATIVE; TYRAMINE;

ACYLATION; ALKYLATION; AMINATION; ANTICOAGULATION; BIOSYNTHESIS; CHEMICAL MODIFICATION; DRUG PROTEIN BINDING; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ESTERIFICATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYDROGENATION; ISOTOPE LABELING; METASTASIS; METHYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; RADIOIODINATION; SHORT SURVEY; SUBSTITUTION REACTION; SULFONATION;

ACYLATION; ALKYLATION; AMIDES; CARBOHYDRATE SEQUENCE; ESTERS; HEPARIN; HEPARIN ANTAGONISTS; HEPARITIN SULFATE; MOLECULAR SEQUENCE DATA;

EUKARYOTA; PROKARYOTA;

EID: 33646915292     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carres.2006.04.014     Document Type: Short Survey

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