Oligomannurarate sulfate, a novel heparanase inhibitor simultaneously targeting basic fibroblast growth factor, combats tumor angiogenesis and metastasis

Cancer Research

Volumn 66, Issue 17, 2006, Pages 8779-8787

  Zhao, Huajun ^a   Liu, Haiying ^a,b   Chen, Yi ^a   Xin, Xianliang ^b   Li, Jing ^b   Hou, Yongtai ^a   Zhang, Zhonghua ^a   Zhang, Xiongwen ^a   Xie, Chengying ^a   Geng, Meiyu ^a,b   Ding, Jian ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; ENZYME INHIBITOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HEPARANASE; LOW MOLECULAR WEIGHT HEPARIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OLIGOMANNURARATE SULFATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER INVASION; CARCINOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING; DRUG COMPETITION; DRUG EFFICACY; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; IC 50; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR DOWN REGULATION; SURFACE PLASMON RESONANCE; TUMOR GROWTH; TUMOR XENOGRAFT;

ALLANTOIS; ANGIOGENESIS INHIBITORS; ANIMALS; AORTA; CATTLE; CELL MOVEMENT; CHORION; ENZYME INHIBITORS; FIBROBLAST GROWTH FACTOR 2; GLUCURONIDASE; HUMANS; MANNANS; MUSCLE, SMOOTH, VASCULAR; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; RATS; SURFACE PLASMON RESONANCE;

EID: 33749008541     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-1382     Document Type: Article

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