Rapid and efficient microwave-assisted synthesis of highly sulfated organic scaffolds

Tetrahedron Letters

Volumn 48, Issue 38, 2007, Pages 6754-6758

  Raghuraman, Arjun ^a   Riaz, Muhammad ^a   Hindle, Michael ^a   Desai, Umesh R ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSAMINOGLYCAN; ORGANIC COMPOUND; SULFATE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; MICROWAVE IRRADIATION; MOLECULAR RECOGNITION; REACTION ANALYSIS; REACTION TIME; STRUCTURE ANALYSIS; SULFATION; SYNTHESIS;

EID: 34548040716     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.07.100     Document Type: Article

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22. See Supplementary data for synthesis of starting materials.
23. RP-HPLC profile showed peaks from 4.3 to 6.0 min, in addition to one at 9.0 min. The peak at 4.3 was subsequently isolated after optimization of conditions and determined to be per-sulfated (1s). The peak at 9.0 min was identified as 1 by comparison with synthetically pure sample. Conversions (%) were determined by area normalization.
24. -] 200.99; found, 200.8.