Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis

Virology

Volumn 430, Issue 1, 2012, Pages 43-52

  Rasmussen, Angela L ^a   Wang, I Ming ^b   Shuhart, Margaret C ^c   Proll, Sean C ^a   He, Yudong ^b   Cristescu, Razvan ^b   Roberts, Chris ^b   Carter, Victoria S ^a   Williams, Christopher M ^a   Diamond, Deborah L ^a   Bryan, Janine T ^a   Ulrich, Roger ^b,d   Korth, Marcus J ^a   Thomassen, Lisa V ^a   Katze, Michael G ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d GILEAD SCIENCES   (United States)

Author keywords

Gene expression; HCV HIV coinfection; Hepatic fibrosis; Hepatitis C virus; Human immunodeficiency virus; Liver; Pathogenesis; Peripheral blood; Systems biology

Indexed keywords

ADULT; ARTICLE; CELL ACTIVATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FIBROGENESIS; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEPATITIS C; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNOPATHOGENESIS; LIVER BIOPSY; LIVER FIBROSIS; MALE; MICROARRAY ANALYSIS; MIXED INFECTION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; STELLATE CELL;

ADULT; BIOPSY; CYTOKINES; FEMALE; GENE EXPRESSION PROFILING; HEPATIC STELLATE CELLS; HEPATITIS C; HIV INFECTIONS; HUMANS; LEUKOCYTES, MONONUCLEAR; LIVER; LYMPHOCYTE ACTIVATION; MALE; MICROARRAY ANALYSIS; MIDDLE AGED;

HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84861833699     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2012.04.011     Document Type: Article

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