Short communication: Oxidative stress in HIV-infected individuals: A cross-sectional study

AIDS Research and Human Retroviruses

Volumn 25, Issue 12, 2009, Pages 1307-1311

  Wanchu, Ajay ^a   Rana, S V ^a   Pallikkuth, Suresh ^a   Sachdeva, Ravinder Kaur ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EFAVIRENZ; GLUTATHIONE; LAMIVUDINE; LAMIVUDINE PLUS NEVIRAPINE PLUS STAVUDINE; LAMIVUDINE PLUS NEVIRAPINE PLUS ZIDOVUDINE; LIPID PEROXIDASE; NELFINAVIR; ZIDOVUDINE;

ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL;

ADULT; CROSS-SECTIONAL STUDIES; FEMALE; GLUTATHIONE; HIV INFECTIONS; HUMANS; LIPID PEROXIDATION; MALE; MIDDLE AGED; OXIDATIVE STRESS;

EID: 73149120058     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2009.0062     Document Type: Article

References (25)

1. Wong GHW, McHugh T, Weber R, and Goeddel DV: Tumor necrosis factor alpha selectively sensitizes human immunodeficiency virus infected cells to heat and radiation. Proc Natl Acad Sci USA 1991;88:4372-4376.
2. Schreck R, Rieber P, and Baeuerle PA: Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kB transcription factor and HIV-1. EMBO J 1991;10:2247-2258.
3. Das UN, Podma M, Sogar PS, Ramesh G, and Koratkar R: Stimulation of free radical generation in human leucocytes by various agents including tumor necrosis factor is a calmodulin-dependent process. Biochem Biophys Res Commun 1990;167:1030-1036.
4. McCord JM: The superoxide free radical: Its biochemistry and pathophysiology. Surgery 1983;94:412-414.
5. Freeman BA and Crapo JD: Biology of disease. Free radicals and tissue injury. Lab Invest 1983;47:412-426.
6. Halliwell B: Oxidants and human disease: Some new concepts. FASEB J 1987;1:358-364.
7. Beutler E: Nutritional and metabolic aspects of glutathione. Annu Rev Nutr 1989;9:287-302.
8. Droge W, Eck HP, Gmunder H, and Mihm S: Modulation of lymphocyte functions and immune responses by cysteine and cysteine derivatives. Am J Med Suppl 1991;3C:140S- 144S.
9. Smyth MJ: Glutathione modulates activation-dependent proliferation of human peripheral blood lymphocyte populations without regulating their activated function. J Immunol 1991;146:1921-1927.
10. Buhl R, Holroyd KJ, Mastrangeli A, et al.: Systemic glutathione deficiency in symptom-free HIV-seropositive individuals. Lancet 1989;2:1294-1298.
11. De Quay B, Malinverni R, and Lauterberg BH: Glutathione depletion in HIV-infected patients: Role of cysteine deficiency and effect of oral N-acetylcysteine. AIDS 1992;6:815-819.
12. Roederer M F, Staal JT, Anderson M, et al.: Dysregulation of leukocyte glutathione in AIDS. Ann NY Acad Sci 1993;677: 113-125.
13. Kalebic T, Kinter A, Pol G, Anderson ME, Meister A, and Fauci AS: Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine. Proc Natl Acad Sci USA 1991;88:986-990.
14. Herzenberg LA, De Rosa SC, Dubs JG, et al.: Glutathione deficiency is associated with impaired survival in HIV disease. Proc Natl Acad Sci USA 1997;94:1967-1972.
15. World Health Organization: Scaling up antiretroviral therapy in resource-limited settings. Available at www.who. int=docstore=hiv=scaling=summ. html (accessed on 5 March 2009).
16. Ohkawa H, Oshishi N and Yagi H: Reaction of linolenic acid hydroperoxide with TBA: J Lipid Res 1978;19:1053-1057.
17. Beutler E, Ducon O, and Kelly BM: Improved method for the determination of blood glutathione. J Lab Clin Med 1963;61: 882-890.
18. Ngondi JL, Oben J, Etame LH, Forkah DM, and Mbanya D: The effect of different combination therapies on oxidative stress markers in HIV infected patients in Cameroon. AIDS Res Ther 2006;3:19.
19. Aukrust P, Muller F, Svardal A, Ueland T, Berge RK, and Froland SS: Disturbed glutathione metabolism and decreased antioxidants levels in human immunodeficiency virus-infected patients during highly active antiretroviral therapy-Potential immunomodulatory effects of antioxidants. J Infect Dis 2003;188:232-238.
20. Staal FJT, Ela SW, Roederer R, Anderson MT, Herzenberg LA, and Herzenberg LA: Glutathione deficiency and human immunodeficiency virus infection. Lancet 1992;339;909-912.
21. Sundaram M, Saghayam S, Priya B, et al.: Changes in antioxidant profile among HIV-infected individuals on generic highly active antiretroviral therapy in Southern India. Int J Infect Dis 2008;12(6):e61-e66. Epub July 14, 2008.
22. Jahoor F, Jackson A, Gazzard B, et al.: Erythrocyte glutathione deficiency in symptom-free HIV infection is associated with decreased synthesis rate. Am J Physiol Endocrinol Metab 1999;276:205-211.
23. Allard JP, Aghdassi E, Chau J, Salit I, and Walmsley S: Oxidative stress and plasma antioxidant micronutrients in humans with HIV infection. Am J Clin Nutr 1998;67:143-147.
24. Buhl R, Jaffe A, Holyroyd KJ, et al.: Systemic glutathione deficiency in symptom-free HIV sero-positive patients. Lancet 1989;2:1294-1296.
25. Bogden JD, Baker H, Frank O, et al.: Micronutrient status and human immunodeficiency virus (HIV) infection. Ann NY Acad Sci 1990;587:189-195.