메뉴 건너뛰기




Volumn 9, Issue 1-2, 2009, Pages 99-110

Pancreatitis-associated protein inhibits human pancreatic stellate cell MMP-1 and -2, TIMP-1 and -2 secretion and RECK expression

Author keywords

Matrix metalloproteinase; Pancreatic stellate cell; Pancreatitis associated protein; Tissue inhibitors of matrix metalloproteinases

Indexed keywords

BROXURIDINE; CELL PROTEIN; GELATINASE A; INTERSTITIAL COLLAGENASE; MESSENGER RNA; PANCREATITIS ASSOCIATED PROTEIN; PROTEIN RECK; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

EID: 57449095902     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1159/000178880     Document Type: Article
Times cited : (19)

References (53)
  • 3
    • 33747588068 scopus 로고    scopus 로고
    • Role of stellate cells in pancreatic fibrogenesis associated with acute and chronic pancreatitis
    • Bachem MG, Zhou Z, Zhou S, Siech M: Role of stellate cells in pancreatic fibrogenesis associated with acute and chronic pancreatitis. J Gastroenterol Hepatol 2006; 21(suppl 3): S92-S96.
    • (2006) J Gastroenterol Hepatol , vol.21 , Issue.SUPPL. 3
    • Bachem, M.G.1    Zhou, Z.2    Zhou, S.3    Siech, M.4
  • 6
    • 0036354166 scopus 로고    scopus 로고
    • Pancreatic stellate cell activation and MMP production in experimental pancreatic fibrosis
    • Yokota T, Denham W, Murayama K, Pelham C, Joehl R, Bell RH Jr: Pancreatic stellate cell activation and MMP production in experimental pancreatic fibrosis. J Surg Res 2001; 104: 106-111.
    • (2001) J Surg Res , vol.104 , pp. 106-111
    • Yokota, T.1    Denham, W.2    Murayama, K.3    Pelham, C.4    Joehl, R.5    Bell Jr, R.H.6
  • 8
    • 0037302934 scopus 로고    scopus 로고
    • Rat pancreatic stellate cells secrete matrix metalloproteinases: Implications for extracellular matrix turnover
    • Phillips PA, McCarroll JA, Park S, Wu MJ, Pirola R, Korsten M, Wilson JS, Apte MV: Rat pancreatic stellate cells secrete matrix metalloproteinases: implications for extracellular matrix turnover. Gut 2003; 52: 275- 282.
    • (2003) Gut , vol.52 , pp. 275-282
    • Phillips, P.A.1    McCarroll, J.A.2    Park, S.3    Wu, M.J.4    Pirola, R.5    Korsten, M.6    Wilson, J.S.7    Apte, M.V.8
  • 9
    • 0029911680 scopus 로고    scopus 로고
    • Matrix turnover in fibrogenesis
    • Iredale JP: Matrix turnover in fibrogenesis. Hepatogastroenterology 1996; 43: 56-71.
    • (1996) Hepatogastroenterology , vol.43 , pp. 56-71
    • Iredale, J.P.1
  • 10
    • 0025847582 scopus 로고
    • Matrix metalloproteinases and their inhibitors in connective tissue remodeling
    • Woessner JF Jr: Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J 1991; 5: 2145-2154.
    • (1991) FASEB J , vol.5 , pp. 2145-2154
    • Woessner Jr, J.F.1
  • 12
    • 0029888478 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase- 1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis
    • Iredale JP, Benyon RC, Arthur MJ, Ferris WF, Alcolado R, Winwood PJ, Clark N, Murphy G: Tissue inhibitor of metalloproteinase- 1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis. Hepatology 1996; 24: 176-184.
    • (1996) Hepatology , vol.24 , pp. 176-184
    • Iredale, J.P.1    Benyon, R.C.2    Arthur, M.J.3    Ferris, W.F.4    Alcolado, R.5    Winwood, P.J.6    Clark, N.7    Murphy, G.8
  • 13
    • 0035819527 scopus 로고    scopus 로고
    • Development of matrix metalloproteinase inhibitors in cancer therapy
    • Hidalgo M, Eckhardt SG: Development of matrix metalloproteinase inhibitors in cancer therapy. J Natl Cancer Inst 2001; 93: 178- 193.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 178-193
    • Hidalgo, M.1    Eckhardt, S.G.2
  • 14
    • 0019422999 scopus 로고
    • An inhibitor of collagenase from human amniotic fluid. Purification, characterization and action on metalloproteinases
    • Murphy G, Cawston TE, Reynolds JJ: An inhibitor of collagenase from human amniotic fluid. Purification, characterization and action on metalloproteinases. Biochem J 1981; 195: 167-170.
    • (1981) Biochem J , vol.195 , pp. 167-170
    • Murphy, G.1    Cawston, T.E.2    Reynolds, J.J.3
  • 15
    • 0024394212 scopus 로고
    • Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase inhibitor family
    • Stetler-Stevenson WG, Krutzsch HC, Liotta LA: Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase inhibitor family. J Biol Chem 1989; 264: 17374-17378.
    • (1989) J Biol Chem , vol.264 , pp. 17374-17378
    • Stetler-Stevenson, W.G.1    Krutzsch, H.C.2    Liotta, L.A.3
  • 16
    • 0026794057 scopus 로고
    • A new inhibitor of metalloproteinases from chicken: ChIMP-3. A third member of the TIMP family
    • Pavloff N, Staskus PW, Kishnani NS, Hawkes SP: A new inhibitor of metalloproteinases from chicken: ChIMP-3. A third member of the TIMP family. J Biol Chem 1992; 267: 17321-17326.
    • (1992) J Biol Chem , vol.267 , pp. 17321-17326
    • Pavloff, N.1    Staskus, P.W.2    Kishnani, N.S.3    Hawkes, S.P.4
  • 17
    • 0031029248 scopus 로고    scopus 로고
    • Murine tissue inhibitor of metalloproteinases-4 (TIMP-4): CDNA isolation and expression in adult mouse tissues
    • Leco KJ, Apte SS, Taniguchi GT, Hawkes SP, Khokha R, Schultz GA, Edwards DR: Murine tissue inhibitor of metalloproteinases-4 (TIMP-4): cDNA isolation and expression in adult mouse tissues. FEBS Lett 1997; 401: 213-217.
    • (1997) FEBS Lett , vol.401 , pp. 213-217
    • Leco, K.J.1    Apte, S.S.2    Taniguchi, G.T.3    Hawkes, S.P.4    Khokha, R.5    Schultz, G.A.6    Edwards, D.R.7
  • 21
    • 0027952728 scopus 로고
    • The acute phase reaction of the exocrine pancreas. Gene expression and synthesis of pancreatitis- associated proteins
    • Keim V, Iovanna JL, Dagorn JC: The acute phase reaction of the exocrine pancreas. Gene expression and synthesis of pancreatitis- associated proteins. Digestion 1994; 55: 65-72.
    • (1994) Digestion , vol.55 , pp. 65-72
    • Keim, V.1    Iovanna, J.L.2    Dagorn, J.C.3
  • 22
    • 0035877745 scopus 로고    scopus 로고
    • A family of 16-kDa pancreatic secretory stress proteins form highly organized fibrillar structures upon tryptic activation
    • Graf R, Schiesser M, Scheele GA, Marquardt K, Frick TW, Ammann RW, Bimmler D: A family of 16-kDa pancreatic secretory stress proteins form highly organized fibrillar structures upon tryptic activation. J Biol Chem 2001; 276: 21028-21038.
    • (2001) J Biol Chem , vol.276 , pp. 21028-21038
    • Graf, R.1    Schiesser, M.2    Scheele, G.A.3    Marquardt, K.4    Frick, T.W.5    Ammann, R.W.6    Bimmler, D.7
  • 23
    • 0036068097 scopus 로고    scopus 로고
    • Coordinate regulation of secretory stress proteins (PSP/reg, PAP I, PAP II, and PAP III) in the rat exocrine pancreas during experimental acute pancreatitis
    • Graf R, Schiesser M, Lussi A, Went P, Scheele GA, Bimmler D: Coordinate regulation of secretory stress proteins (PSP/reg, PAP I, PAP II, and PAP III) in the rat exocrine pancreas during experimental acute pancreatitis. J Surg Res 2002; 105: 136-144.
    • (2002) J Surg Res , vol.105 , pp. 136-144
    • Graf, R.1    Schiesser, M.2    Lussi, A.3    Went, P.4    Scheele, G.A.5    Bimmler, D.6
  • 24
    • 4644367390 scopus 로고    scopus 로고
    • Coordinate regulation of PSP/reg and PAP isoforms as a family of secretory stress proteins in an animal model of chronic pancreatitis
    • Bimmler D, Schiesser M, Perren A, Scheele G, Angst E, Meili S, Ammann R, Graf R: Coordinate regulation of PSP/reg and PAP isoforms as a family of secretory stress proteins in an animal model of chronic pancreatitis. J Surg Res 2004; 118: 122-135.
    • (2004) J Surg Res , vol.118 , pp. 122-135
    • Bimmler, D.1    Schiesser, M.2    Perren, A.3    Scheele, G.4    Angst, E.5    Meili, S.6    Ammann, R.7    Graf, R.8
  • 25
    • 0028017744 scopus 로고
    • Rat pancreatitis-associated protein is expressed in relation to severity of experimental pancreatitis
    • Keim V, Willemer S, Iovanna JL, Adler G, Dagorn JC: Rat pancreatitis-associated protein is expressed in relation to severity of experimental pancreatitis. Pancreas 1994; 9: 606-612.
    • (1994) Pancreas , vol.9 , pp. 606-612
    • Keim, V.1    Willemer, S.2    Iovanna, J.L.3    Adler, G.4    Dagorn, J.C.5
  • 26
    • 0031946284 scopus 로고    scopus 로고
    • The pancreatitis- associated protein is induced by free radicals in AR4-2J cells and confers cell resistance to apoptosis
    • Ortiz EM, Dusetti NJ, Vasseur S, Malka D, Bödeker H, Dagorn JC, Iovanna JL: The pancreatitis- associated protein is induced by free radicals in AR4-2J cells and confers cell resistance to apoptosis. Gastroenterology 1998; 114: 808.
    • (1998) Gastroenterology , vol.114 , pp. 808
    • Ortiz, E.M.1    Dusetti, N.J.2    Vasseur, S.3    Malka, D.4    Bödeker, H.5    Dagorn, J.C.6    Iovanna, J.L.7
  • 27
    • 0033860040 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha triggers antiapoptotic mechanisms in rat pancreatic cells through pancreatitis-associated protein I activation
    • Malka D, Vasseur S, Bodeker H, Ortiz EM, Dusetti NJ, Verrando P, Dagorn JC, Iovanna JL: Tumor necrosis factor alpha triggers antiapoptotic mechanisms in rat pancreatic cells through pancreatitis-associated protein I activation. Gastroenterology 2000; 119: 816.
    • (2000) Gastroenterology , vol.119 , pp. 816
    • Malka, D.1    Vasseur, S.2    Bodeker, H.3    Ortiz, E.M.4    Dusetti, N.J.5    Verrando, P.6    Dagorn, J.C.7    Iovanna, J.L.8
  • 28
    • 0036840337 scopus 로고    scopus 로고
    • Expression of the regenerating gene family in inflammatory bowel disease mucosa: Reg Ialpha upregulation, processing, and antiapoptotic activity
    • Dieckgraefe BK, Crimmins DL, Landt V, Houchen C, Anant S, Porche-Sorbet R, Ladenson JH: Expression of the regenerating gene family in inflammatory bowel disease mucosa: Reg Ialpha upregulation, processing, and antiapoptotic activity. J Investig Med 2002; 50: 421.
    • (2002) J Investig Med , vol.50 , pp. 421
    • Dieckgraefe, B.K.1    Crimmins, D.L.2    Landt, V.3    Houchen, C.4    Anant, S.5    Porche-Sorbet, R.6    Ladenson, J.H.7
  • 29
    • 1342304085 scopus 로고    scopus 로고
    • p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I
    • Vasseur S, Folch Puy E, Hlouschek V, Garcia S, Fiedler F, Lerch MM, Dagorn JC, Closa D, Iovanna JL: p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I. J Biol Chem 2004; 279: 7199-7207.
    • (2004) J Biol Chem , vol.279 , pp. 7199-7207
    • Vasseur, S.1    Folch Puy, E.2    Hlouschek, V.3    Garcia, S.4    Fiedler, F.5    Lerch, M.M.6    Dagorn, J.C.7    Closa, D.8    Iovanna, J.L.9
  • 32
    • 33745063177 scopus 로고    scopus 로고
    • Caerulein-induced acute pancreatitis in mice that constitutively overexpress Reg/ PAP genes
    • Norkina O, Graf R, Appenzeller P, De Lisle RC: Caerulein-induced acute pancreatitis in mice that constitutively overexpress Reg/ PAP genes. BMC Gastroenterol 2006; 6: 16.
    • (2006) BMC Gastroenterol , vol.6 , pp. 16
    • Norkina, O.1    Graf, R.2    Appenzeller, P.3    De Lisle, R.C.4
  • 33
    • 0033969266 scopus 로고    scopus 로고
    • Platelet-derived growth factors stimulate proliferation and extracellular matrix synthesis of pancreatic stellate cells: Implications in pathogenesis of pancreas fibrosis
    • Luttenberger T, Schmid-Kotsas A, Menke A, Siech M, Beger H, Adler G, Grunert A, Bachem MG: Platelet-derived growth factors stimulate proliferation and extracellular matrix synthesis of pancreatic stellate cells: implications in pathogenesis of pancreas fibrosis. Lab Invest 2000; 80: 47-55.
    • (2000) Lab Invest , vol.80 , pp. 47-55
    • Luttenberger, T.1    Schmid-Kotsas, A.2    Menke, A.3    Siech, M.4    Beger, H.5    Adler, G.6    Grunert, A.7    Bachem, M.G.8
  • 34
    • 0032704154 scopus 로고    scopus 로고
    • Lipopolysaccharide- activated macrophages stimulate the synthesis of collagen type I and C-fibronectin in cultured pancreatic stellate cells
    • Schmid-Kotsas A, Gross HJ, Menke A, Weidenbach H, Adler G, Siech M, Beger H, Grunert A, Bachem MG: Lipopolysaccharide- activated macrophages stimulate the synthesis of collagen type I and C-fibronectin in cultured pancreatic stellate cells. Am J Pathol 1999; 155: 1749-1758.
    • (1999) Am J Pathol , vol.155 , pp. 1749-1758
    • Schmid-Kotsas, A.1    Gross, H.J.2    Menke, A.3    Weidenbach, H.4    Adler, G.5    Siech, M.6    Beger, H.7    Grunert, A.8    Bachem, M.G.9
  • 35
    • 0018850985 scopus 로고
    • A simple, rapid, and sensitive DNA assay procedure
    • Labarca C, Paigen K: A simple, rapid, and sensitive DNA assay procedure. Anal Biochem 1980; 102: 344-352.
    • (1980) Anal Biochem , vol.102 , pp. 344-352
    • Labarca, C.1    Paigen, K.2
  • 37
    • 0026334074 scopus 로고
    • Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectinrelated protein overexpressed during acute experimental pancreatitis
    • Iovanna J, Orelle B, Keim V, Dagorn J-C: Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectinrelated protein overexpressed during acute experimental pancreatitis. J Biol Chem 1991; 266: 24664-24669.
    • (1991) J Biol Chem , vol.266 , pp. 24664-24669
    • Iovanna, J.1    Orelle, B.2    Keim, V.3    Dagorn, J.-C.4
  • 38
    • 0026069120 scopus 로고
    • Characterization of a rat pancreatic secretory protein associated with pancreatitis
    • Keim V, Iovanna JL, Rohr G, Usadel KH, Dagorn JC: Characterization of a rat pancreatic secretory protein associated with pancreatitis. Gastroenterology 1991; 100: 775- 782.
    • (1991) Gastroenterology , vol.100 , pp. 775-782
    • Keim, V.1    Iovanna, J.L.2    Rohr, G.3    Usadel, K.H.4    Dagorn, J.C.5
  • 39
    • 0027074133 scopus 로고
    • Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases
    • Orelle B, Keim V, Masciotra L, Dagorn JC, Iovanna JL: Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases. J Clin Invest 1992; 90: 2284-2291.
    • (1992) J Clin Invest , vol.90 , pp. 2284-2291
    • Orelle, B.1    Keim, V.2    Masciotra, L.3    Dagorn, J.C.4    Iovanna, J.L.5
  • 40
  • 41
    • 4544289943 scopus 로고    scopus 로고
    • Targeted inhibition of gene expression of pancreatitis-associated proteins exacerbates the severity of acute pancreatitis in rats
    • Zhang H, Kandil E, Lin YY, Levi G, Zenilman ME: Targeted inhibition of gene expression of pancreatitis-associated proteins exacerbates the severity of acute pancreatitis in rats. Scand J Gastroenterol 2004; 39: 870- 881.
    • (2004) Scand J Gastroenterol , vol.39 , pp. 870-881
    • Zhang, H.1    Kandil, E.2    Lin, Y.Y.3    Levi, G.4    Zenilman, M.E.5
  • 42
    • 0042209616 scopus 로고    scopus 로고
    • HIP/PAP stimulates liver regeneration after partial hepatectomy and combines mitogenic and anti-apoptotic functions through the PKA signaling pathway
    • Simon MT, Pauloin A, Normand G, Lieu HT, Mouly H, Pivert G, Carnot F, Tralhao JG, Brechot C, Christa L: HIP/PAP stimulates liver regeneration after partial hepatectomy and combines mitogenic and anti-apoptotic functions through the PKA signaling pathway. FASEB J 2003; 17: 1441-1450.
    • (2003) FASEB J , vol.17 , pp. 1441-1450
    • Simon, M.T.1    Pauloin, A.2    Normand, G.3    Lieu, H.T.4    Mouly, H.5    Pivert, G.6    Carnot, F.7    Tralhao, J.G.8    Brechot, C.9    Christa, L.10
  • 46
    • 0032952079 scopus 로고    scopus 로고
    • Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and on-parenchymal cells of rat liver: Regulation by TNF- and TGF- - 1
    • Knittel T, Mehde M, Kobold D, Saile B, Dinter C, Ramadori G: Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and on-parenchymal cells of rat liver: regulation by TNF- and TGF- - 1. J Hepatol 1999; 30: 48-60.
    • (1999) J Hepatol , vol.30 , pp. 48-60
    • Knittel, T.1    Mehde, M.2    Kobold, D.3    Saile, B.4    Dinter, C.5    Ramadori, G.6
  • 47
    • 0034814405 scopus 로고    scopus 로고
    • Extracellular matrix degradation and the role of hepatic stellate cells
    • Benyon RC, Arthur MJ: Extracellular matrix degradation and the role of hepatic stellate cells. Semin Liver Dis 2001; 21: 373-384.
    • (2001) Semin Liver Dis , vol.21 , pp. 373-384
    • Benyon, R.C.1    Arthur, M.J.2
  • 48
    • 0024314801 scopus 로고
    • Maintenance of differentiated phenotype of cultured rat hepatic lipocytes by basement membrane matrix
    • Friedman SL, Roll FJ, Boyles J, Arenson DM, Bissell DM: Maintenance of differentiated phenotype of cultured rat hepatic lipocytes by basement membrane matrix. J Biol Chem 1989; 264: 10756-10762.
    • (1989) J Biol Chem , vol.264 , pp. 10756-10762
    • Friedman, S.L.1    Roll, F.J.2    Boyles, J.3    Arenson, D.M.4    Bissell, D.M.5
  • 49
    • 20644465610 scopus 로고    scopus 로고
    • Progelatinase A is produced and activated by rat hepatic stellate cells and promotes their proliferation
    • Benyon RC, Hovell CJ, Da Gaca M, Jones EH, Iredale JP, Arthur MJ: Progelatinase A is produced and activated by rat hepatic stellate cells and promotes their proliferation. Hepatology 1999; 30: 977-986.
    • (1999) Hepatology , vol.30 , pp. 977-986
    • Benyon, R.C.1    Hovell, C.J.2    Da Gaca, M.3    Jones, E.H.4    Iredale, J.P.5    Arthur, M.J.6
  • 50
    • 0030030039 scopus 로고    scopus 로고
    • Expression of tissue inhibitor of metalloproteinases-1 and -2 is increased in fibrotic human liver
    • Benyon RC, Iredale JP, Goddard S, Winwood PJ, Arthur MJ: Expression of tissue inhibitor of metalloproteinases-1 and -2 is increased in fibrotic human liver. Gastroenterology 1996; 110: 821-831.
    • (1996) Gastroenterology , vol.110 , pp. 821-831
    • Benyon, R.C.1    Iredale, J.P.2    Goddard, S.3    Winwood, P.J.4    Arthur, M.J.5
  • 51
    • 0032146551 scopus 로고    scopus 로고
    • Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
    • Iredale JP, Benyon RC, Pickering J, McCullen M, Northrop M, Pawley S, Hovell C, Arthur MJ: Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest 1998; 102: 538-549.
    • (1998) J Clin Invest , vol.102 , pp. 538-549
    • Iredale, J.P.1    Benyon, R.C.2    Pickering, J.3    McCullen, M.4    Northrop, M.5    Pawley, S.6    Hovell, C.7    Arthur, M.J.8
  • 52
    • 0034615550 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases: Evolution, structure and function
    • Brew K, Dinakarpandian D, Nagase H: Tissue inhibitors of metalloproteinases: evolution, structure and function. Biochim Biophys Acta 2000; 1477: 267-283.
    • (2000) Biochim Biophys Acta , vol.1477 , pp. 267-283
    • Brew, K.1    Dinakarpandian, D.2    Nagase, H.3
  • 53
    • 0025825501 scopus 로고
    • Decreased expression of tissue inhibitor of metalloproteinases in metastatic tumor cells leading to increased levels of collagenase activity
    • Ponton A, Coulombe B, Skup D: Decreased expression of tissue inhibitor of metalloproteinases in metastatic tumor cells leading to increased levels of collagenase activity. Cancer Res 1991; 51: 2138-2143.
    • (1991) Cancer Res , vol.51 , pp. 2138-2143
    • Ponton, A.1    Coulombe, B.2    Skup, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.