HIV Increases HCV Replication in a TGF-β1-Dependent Manner

Gastroenterology

Volumn 134, Issue 3, 2008, Pages 803-811

  Lin, Wenyu ^a   Weinberg, Ethan M ^a   Tai, Andrew W ^a   Peng, Lee F ^a   Brockman, Mark A ^b   Kim, Kyung Ah ^a   Kim, Sun Suk ^a   Borges, Carolina B ^a   Shao, Run Xuan ^a   Chung, Raymond T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; GLYCOPROTEIN GP 120; INTERFERON; NEUTRALIZING ANTIBODY; RECEPTOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CONTROLLED STUDY; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; LIVER CELL; LIVER FIBROSIS; MIXED INFECTION; NONHUMAN; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROVIRUS; REPLICON; TREATMENT RESPONSE; VIRUS NEUTRALIZATION; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS VIRULENCE;

EID: 39749180475     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2008.01.005     Document Type: Article

References (34)

1. S.R. Vlahakis A. Villasis-Keever T.S. Gomez Human immunodeficiency virus-induced apoptosis of human hepatocytes via CXCR4 J Infect Dis 188 2003 1455 1460
2. K.E. Sherman M. Peters M.J. Koziel HIV and liver disease forum: conference proceedings Hepatology 45 2007 1566 1577
3. R. Gallo F. Wong-Staal L. Montagnier HIV/HTLV gene nomenclature Nature 333 1988 504
4. I. Bica B. McGovern R. Dhar Increasing mortality due to end-stage liver disease in patients with human immunodeficiency virus infection Clin Infect Dis 32 2001 492 497
5. H. Choe M. Farzan Y. Sun The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates Cell 85 1996 1135 1148
6. S.R. Vlahakis A. Algeciras-Schimnich G. Bou Chemokine-receptor activation by env determines the mechanism of death in HIV-infected and uninfected T lymphocytes J Clin Invest 107 2001 207 215
7. A. Algeciras-Schimnich S.R. Vlahakis A. Villasis-Keever CCR5 mediates Fas- and caspase-8 dependent apoptosis of both uninfected and HIV infected primary human CD4 T cells AIDS 16 2002 1467 1478
8. J.T. Blackard F. Komurian-Pradel M. Perret Intrahepatic cytokine expression is downregulated during HCV/HIV co-infection J Med Virol 78 2006 202 207
9. T. Wakita T. Pietschmann T. Kato Production of infectious hepatitis C virus in tissue culture from a cloned viral genome Nat Med 11 2005 791 796
10. J. Zhong P. Gastaminza G. Cheng Robust hepatitis C virus infection in vitro Proc Natl Acad Sci U S A 102 2005 9294 9299
11. M. Ikeda M. Yi K. Li Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells J Virol 76 2002 2997 3006
12. M. Ikeda K. Abe H. Dansako Efficient replication of a full-length hepatitis C virus genome, strain O, in cell culture, and development of a luciferase reporter system Biochem Biophys Res Commun 329 2005 1350 1359
13. S. Kim L. Peng W. Lin A cell-based, high-throughput screen for small molecule regulators of hepatitis C virus replication Gastroenterology 132 2007 311 320
14. M.A. Brockman G.O. Tanzi B.D. Walker Use of a novel GFP reporter cell line to examine replication capacity of CXCR4- and CCR5-tropic HIV-1 by flow cytometry J Virol Methods 131 2006 134 142
15. S. Gartner P. Markovits D.M. Markovitz The role of mononuclear phagocytes in HTLV-III/LAV infection Science 233 1986 215 219
16. Y. Morikawa H. Overton J. Moore Expression of HIV-1 gp120 and human soluble CD4 by recombinant baculoviruses and their interaction in vitro AIDS Res Hum Retroviruses 6 1990 765 773
17. W. Lin W.H. Choe Y. Hiasa Hepatitis C virus expression suppresses interferon signaling by degrading STAT1 Gastroenterology 128 2005 1034 1041
18. W. Lin S.S. Kim E. Yeung Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain J Virol 80 2006 9226 9235
19. V. Castet C. Fournier A. Soulier Alpha interferon inhibits hepatitis C virus replication in primary human hepatocytes infected in vitro J Virol 76 2002 8189 8199
20. S. Pal L.M. Schnapp HIV-infected lymphocytes regulate fibronectin synthesis by TGF beta 1 secretion J Immunol 172 2004 3189 3195
21. P.L. Cheng M.H. Chang C.H. Chao Hepatitis C viral proteins interact with Smad3 and differentially regulate TGF-beta/Smad3-mediated transcriptional activation Oncogene 23 2004 7821 7838
22. K. Grungreiff D. Reinhold S. Ansorge Serum concentrations of sIL-2R, IL-6, TGF-beta1, neopterin, and zinc in chronic hepatitis C patients treated with interferon-alpha Cytokine 11 1999 1076 1080
23. T. Kimura T. Saito M. Yoshimura Association of transforming growth factor-beta 1 functional polymorphisms with natural clearance of hepatitis C virus J Infect Dis 193 2006 1371 1374
24. K.L. McCann F. Imani Transforming growth factor beta enhances respiratory syncytial virus replication and tumor necrosis factor alpha induction in human epithelial cells J Virol 81 2007 2880 2886
25. V. Ravichandran P.N. Jensen E.O. Major MEK1/2 inhibitors block basal and transforming growth factor {beta}1-stimulated JC virus multiplication J Virol 81 2007 6412 6418
26. D.R. Littman Chemokine receptors: keys to AIDS pathogenesis? Cell 93 1998 677 680
27. M.R. Capobianchi C. Barresi P. Borghi Human immunodeficiency virus type 1 gp120 stimulates cytomegalovirus replication in monocytes: possible role of endogenous interleukin-8 J Virol 71 1997 1591 1597
28. A. Balasubramanian R.K. Ganju J.E. Groopman Hepatitis C virus and HIV envelope proteins collaboratively mediate interleukin-8 secretion through activation of p38 MAP kinase and SHP2 in hepatocytes J Biol Chem 278 2003 35755 35766
29. L.E. Wilson M. Torbenson J. Astemborski Progression of liver fibrosis among injection drug users with chronic hepatitis C Hepatology 43 2006 788 795
30. G. Zauli B.R. Davis M.C. Re tat protein stimulates production of transforming growth factor-beta 1 by marrow macrophages: a potential mechanism for human immunodeficiency virus-1-induced hematopoietic suppression Blood 80 1992 3036 3043
31. M.O. Li Y.Y. Wan S. Sanjabi Transforming growth factor-beta regulation of immune responses Annu Rev Immunol 24 2006 99 146
32. S. Chen D.L. Tuttle J.T. Oshier Transforming growth factor-beta1 increases CXCR4 expression, stromal-derived factor-1alpha-stimulated signalling and human immunodeficiency virus-1 entry in human monocyte-derived macrophages Immunology 114 2005 565 574
33. T. Murata T. Ohshima M. Yamaji Suppression of hepatitis C virus replicon by TGF-beta Virology 331 2005 407 417
34. N. Brau M. Salvatore C.F. Rios-Bedoya Slower fibrosis progression in HIV/HCV-coinfected patients with successful HIV suppression using antiretroviral therapy J Hepatol 44 2006 47 55