Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, Part 2: Epidermal H 2O2/ONOO--mediated stress in vitiligo hampers indoleamine 2,3-dioxygenase and aryl hydrocarbon receptor-mediated immune response signaling

FASEB Journal

Volumn 26, Issue 6, 2012, Pages 2471-2485

  Schallreuter, Karin U ^a,b   Salem, Mohamed A E L ^a,b   Gibbons, Nick C J ^a,b   Maitland, Derek J ^b   Marsch, Elke ^a   Elwary, Souna M A ^a,b,c   Healey, Andrew R ^b  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Hydrogen peroxide; IDO; Peroxynitrite; Treg

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CYCLOOXYGENASE 2; CYTOCHROME P450 1A1; HYDROGEN PEROXIDE; INDOLEAMINE 2,3 DIOXYGENASE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; TRYPTOPHAN; TRYPTOPHAN HYDROXYLASE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FENTON REACTION; FOURIER TRANSFORM MASS SPECTROMETRY; HUMAN; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MASS SPECTROMETRY; PRIORITY JOURNAL; RAMAN SPECTROMETRY; REGULATORY T LYMPHOCYTE; STRESS; VITILIGO;

COMPUTER SIMULATION; EPIDERMIS; HUMANS; HYDROGEN PEROXIDE; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; OXIDATIVE STRESS; PEROXYNITROUS ACID; RECEPTORS, ARYL HYDROCARBON; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TRYPTOPHAN; VITILIGO;

EID: 84861778637     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-201897     Document Type: Article

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