Influence of the Nuclear Membrane, Active Transport, and Cell Shape on the Hes1 and p53-Mdm2 Pathways: Insights from Spatio-temporal Modelling

Bulletin of Mathematical Biology

Volumn 74, Issue 7, 2012, Pages 1531-1579

  Sturrock, Marc ^a   Terry, Alan J ^a   Xirodimas, Dimitris P ^b   Thompson, Alastair M ^c   Chaplain, Mark A J ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b CNRS   (France)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Active transport; Cell shape; Hes1; Nuclear membrane; p53

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENZYME INHIBITOR; HES1 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; MDM2 PROTEIN, MOUSE; PROTEASOME; PROTEIN MDM2; PROTEIN P53;

ACTIVE TRANSPORT; ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL CULTURE; CELL NUCLEUS MEMBRANE; CELL SHAPE; COMPUTER SIMULATION; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MICROTUBULE; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL SHAPE; CELLS, CULTURED; COMPUTER SIMULATION; ENZYME INHIBITORS; HOMEODOMAIN PROTEINS; MICE; MICROTUBULES; MODELS, BIOLOGICAL; NUCLEAR ENVELOPE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS C-MDM2; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84861756648     PISSN: 00928240     EISSN: 15229602     Source Type: Journal    
DOI: 10.1007/s11538-012-9725-1     Document Type: Article

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