Entrainment of peripheral clock genes by cortisol

Physiological Genomics

Volumn 44, Issue 11, 2012, Pages 607-621

  Mavroudis, Panteleimon D ^a   Scheff, Jeremy D ^b   Calvano, Steve E ^c   Lowry, Stephen F ^c   Androulakis, Ioannis P ^a,b,c  

^a The State University of New Jersey   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Biological oscillations; Circadian rhythms; Clock synchronization; Mathematical model

Indexed keywords

DEXAMETHASONE; DNA; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; MESSENGER RNA;

ARTICLE; BIOLOGICAL RHYTHM; CHRONIC STRESS; CIRCADIAN RHYTHM; CLOCK GENE; CLOCK GENE DESYNCHRONIZATION; CLOCK GENE PER1; CLOCK GENE PER2; CLOCK GENE SYNCHRONIZATION; E4BP4 CLOCK GENE; GENE; GENE LOCUS; HORMONE ACTION; HORMONE RECEPTOR INTERACTION; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LIGHT DARK CYCLE; MATHEMATICAL MODEL; OSCILLATION; PRIORITY JOURNAL; SUPRACHIASMATIC NUCLEUS;

ANIMALS; BIOLOGICAL CLOCKS; CIRCADIAN RHYTHM; HUMANS; HYDROCORTISONE; MAMMALS; MODELS, BIOLOGICAL; SUPRACHIASMATIC NUCLEUS;

MAMMALIA;

EID: 84861735097     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00001.2012     Document Type: Article

References (78)

1. Abraham U, Granada AE, Westermark PO, Heine M, Kramer A, Herzel H. Coupling governs entrainment range of circadian clocks. Mol Syst Biol 6: 438, 2010.
2. An G. In silico experiments of existing and hypothetical cytokine-directed clinical trials using agent-based modeling. Crit Care Med 32: 2050-2060, 2004.
3. An G. Introduction of an agent-based multi-scale modular architecture for dynamic knowledge representation of acute inflammation. Theor Biol Med Model 5: 11, 2008.
4. Antle MC, Foley DK, Foley NC, Silver R. Gates and oscillators: a network model of the brain clock. J Biol Rhythms 18: 339-350, 2003.
5. Antle MC, Foley NC, Foley DK, Silver R. Gates and oscillators II: zeitgebers and the network model of the brain clock. J Biol Rhythms 22: 14-25, 2007.
6. Azama T, Yano M, Oishi K, Kadota K, Hyun K, Tokura H, Nishimura S, Matsunaga T, Iwanaga H, Miki H, Okada K, Hiraoka N, Miyata H, Takiguchi S, Fujiwara Y, Yasuda T, Ishida N, Monden M. Altered expression profiles of clock genes hPer1 and hPer2 in peripheral blood mononuclear cells of cancer patients undergoing surgery. Life Sci 80: 1100-1108, 2007.
7. Balsalobre A. Clock genes in mammalian peripheral tissues. Cell Tissue Res 309: 193-199, 2002.
8. Balsalobre A, Brown SA, Marcacci L, Tronche F, Kellendonk C, Reichardt HM, Schutz G, Schibler U. Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science 289: 2344-2347, 2000.
9. Balsalobre A, Damiola F, Schibler U. A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell 93: 929-937, 1998.
10. Batada NN, Shepp LA, Siegmund DO. Stochastic model of proteinprotein interaction: why signaling proteins need to be colocalized. Proc Natl Acad Sci USA 101: 6445-6449, 2004.
11. Becker-Weimann S, Wolf J, Herzel H, Kramer A. Modeling feedback loops of the mammalian circadian oscillator. Biophys J 87: 3023-3034, 2004.
12. Bernard S, Gonze D, Cajavec B, Herzel H, Kramer A. Synchronization-induced rhythmicity of circadian oscillators in the suprachiasmatic nucleus. PLoS Comput Biol 3: e68, 2007.
13. Boivin DB, James FO, Wu A, Cho-Park PF, Xiong H, Sun ZS. Circadian clock genes oscillate in human peripheral blood mononuclear cells. Blood 102: 4143-4145, 2003.
14. Brown EN, Meehan PM, Dempster AP. A stochastic differential equation model of diurnal cortisol patterns. Am J Physiol Endocrinol Metab 280: E450-E461, 2001.
15. Brown SA, Fleury-Olela F, Nagoshi E, Hauser C, Juge C, Meier CA, Chicheportiche R, Dayer JM, Albrecht U, Schibler U. The period length of fibroblast circadian gene expression varies widely among human individuals. PLoS Biol 3: e338, 2005.
16. Buijs RM, Kalsbeek A. Hypothalamic integration of central and peripheral clocks. Nat Rev Neurosci 2: 521-526, 2001.
17. Burioka N, Takata M, Okano Y, Ohdo S, Fukuoka Y, Miyata M, Takane H, Endo M, Suyama H, Shimizu E. Dexamethasone influences human clock gene expression in bronchial epithelium and peripheral blood mononuclear cells in vitro. Chronobiol Int 22: 585-590, 2005.
18. Carlson DE, Chiu WC. The absence of circadian cues during recovery from sepsis modifies pituitary-adrenocortical function and impairs survival. Shock 29: 127-132, 2008.
19. Chakraborty A, Krzyzanski W, Jusko WJ. Mathematical modeling of circadian cortisol concentrations using indirect response models: comparison of several methods. J Pharmacokinet Pharmacodyn 27: 23-43, 1999.
20. Charmandari E, Chrousos GP, Lambrou GI, Pavlaki A, Koide H, Ng SSM, Kino T. Peripheral CLOCK regulates target-tissue glucocorticoid receptor transcriptional activity in a circadian fashion in man. PLoS ONE 6: e25612, 2011.
21. Chrousos GP, Gold PW. A healthy body in a healthy mind-and vice versa-the damaging power of "uncontrollable" stress. J Clin Endocrinol Metab 83: 1842-1845, 1998.
22. Chrousos GP, Kino T. Intracellular glucocorticoid signaling: a formerly simple system turns stochastic. Sci STKE 2005: pe48, 2005.
23. Cohen MC, Rohtla KM, Lavery CE, Muller JE, Mittleman MA. Meta-analysis of the morning excess of acute myocardial infarction and sudden cardiac death. Am J Cardiol 79: 1512-1516, 1997.
24. Cooley JW, Tukey JW. An algorithm for the machine calculation of complex Fourier series. Math Comp 19: 297-301, 1965.
25. Cuninkova L, Brown SA. Peripheral circadian oscillators: interesting mechanisms and powerful tools. Ann NY Acad Sci 1129: 358-370, 2008.
26. Dickmeis T. Glucocorticoids and the circadian clock. J Endocrinol 200: 3-22, 2009.
27. Dobson CM, Šali A, Karplus M. Protein folding: a perspective from theory and experiment. Angewandte Chemie Int 37: 868-893, 1998.
28. Filipski E, Delaunay F, King VM, Wu MW, Claustrat B, Grechez-Cassiau A, Guettier C, Hastings MH, Francis L. Effects of chronic jet lag on tumor progression in mice. Cancer Res 64: 7879-7885, 2004.
29. Filipski E, King VM, Li X, Granda TG, Mormont MC, Liu X, Claustrat B, Hastings MH, Levi F. Host circadian clock as a control point in tumor progression. J Natl Cancer Inst 94: 690-697, 2002.
30. Forger DB, Peskin CS. Stochastic simulation of the mammalian circadian clock. Proc Natl Acad Sci USA 102: 321-324, 2005.
31. Fu L, Lee CC. The circadian clock: pacemaker and tumour suppressor. Nat Rev Cancer 3: 350-361, 2003.
32. Gachon F, Nagoshi E, Brown SA, Ripperger J, Schibler U. The mammalian circadian timing system: from gene expression to physiology. Chromosoma 113: 103-112, 2004.
33. Garcia-Ojalvo J, Elowitz MB, Strogatz SH. Modeling a synthetic multicellular clock: repressilators coupled by quorum sensing. Proc Natl Acad Sci USA 101: 10955-10960, 2004.
34. Geier F, Becker-Weimann S, Kramer A, Herzel H. Entrainment in a model of the mammalian circadian oscillator. J Biol Rhythms 20: 83-93, 2005.
35. Gillespie DT. The chemical Langevin equation. J Chem Phys 113: 297-306, 2000.
36. Godin PJ, Buchman TG. Uncoupling of biological oscillators: A complementary hypothesis concerning the pathogenesis of multiple organ dysfunction syndrome. Crit Care Med 24: 1107-1116, 1996.
37. Gonze D, Bernard S, Waltermann C, Kramer A, Herzel H. Spontaneous synchronization of coupled circadian oscillators. Biophys J 89: 120-129, 2005.
38. Haimovich B, Calvano J, Haimovich AD, Calvano SE, Coyle SM, Lowry SF. In Vivo endotoxin synchronizes and suppresses clock gene expression in human peripheral blood leukocytes. Crit Care Med 38: 751-758, 2010.
39. Hastings MH, Reddy AB, Maywood ES. A clockwork web: circadian timing in brain and periphery, in health and disease. Nat Rev Neurosci 4: 649-661, 2003.
40. Hobson KG, Havel PJ, McMurtry AL, Lawless MB, Palmieri TL, Greenhalgh DD. Circulating leptin and cortisol after burn injury: loss of diurnal pattern. J Burn Care Rehabil 25: 491-499, 2004.
41. Hobson KG, Havel PJ, McMurtry AL, Lawless MB, Palmieri TL, Greenhalgh DD. Circulating leptin and cortisol after burn injury: loss of diurnal pattern. J Burn Care Res 25: 491-499, 2004.
42. Jeyaraj D, Haldar SM, Wan X, McCauley MD, Ripperger JA, Hu K, Lu Y, Eapen BL, Sharma N, Ficker E, Cutler MJ, Gulick J, Sanbe A, Robbins J, Demolombe S, Kondratov RV, Shea SA, Albrecht U, Wehrens XH, Rosenbaum DS, Jain MK. Circadian rhythms govern cardiac repolarization and arrhythmogenesis. Nature 483: 96-99, 2012.
43. Jin JY, Almon RR, DuBois DC, Jusko WJ. Modeling of corticosteroid pharmacogenomics in rat liver using gene microarrays. J Pharmacol Exp Therapeut 307: 93-109, 2003.
44. Kaern M, Elston TC, Blake WJ, Collins JJ. Stochasticity in gene expression: from theories to phenotypes. Nat Rev Genet 6: 451-464, 2005.
45. Kino T, De Martino MU, Charmandari E, Mirani M, Chrousos GP. Tissue glucocorticoid resistance/hypersensitivity syndromes. J Steroid Biochem Mol Biol 85: 457-467, 2003.
46. Leloup JC, Goldbeter A. Toward a detailed computational model for the mammalian circadian clock. Proc Natl Acad Sci USA 100: 7051-7056, 2003.
47. Lipiner-Friedman D, Sprung CL, Laterre PF, Weiss Y, Goodman SV, Vogeser M, Briegel J, Keh D, Singer M, Moreno R, Bellissant E, Annane D, Corticus Study Group. Adrenal function in sepsis: the retrospective Corticus cohort study. Crit Care Med 35: 1012-1018, 2007.
48. Liu AC, Welsh DK, Ko CH, Tran HG, Zhang EE, Priest AA, Buhr ED, Singer O, Meeker K, Verma IM, Doyle FJ 3rd, Takahashi JS, Kay SA. Intercellular coupling confers robustness against mutations in the SCN circadian clock network. Cell 129: 605-616, 2007.
49. Mi Q, Riviere B, Clermont G, Steed DL, Vodovotz Y. Agent-based model of inflammation and wound healing: insights into diabetic foot ulcer pathology and the role of transforming growth factor-beta1. Wound Repair Regen 15: 671-682, 2007.
50. Miller GE, Chen E, Zhou ES. If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans. Psychol Bull 133: 25-45, 2007.
51. Mirsky HP, Liu AC, Welsh DK, Kay SA, Doyle FJ 3rd. A model of the cell-autonomous mammalian circadian clock. Proc Natl Acad Sci USA 106: 11107-11112, 2009.
52. Mondragon-Palomino O, Danino T, Selimkhanov J, Tsimring L, Hasty J. Entrainment of a population of synthetic genetic oscillators. Science 333: 1315-1319, 2011.
53. Nader N, Chrousos GP, Kino T. Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications. FASEB J 23: 1572-1583, 2009.
54. Nader N, Chrousos GP, Kino T. Interactions of the circadian CLOCK system and the HPA axis. Trends Endocrinol Metab 21: 277-286, 2010.
55. Nagoshi E, Saini C, Bauer C, Laroche T, Naef F, Schibler U. Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cells. Cell 119: 693-705, 2004.
56. Oakley RH, Cidlowski JA. Homologous down regulation of the glucocorticoid receptor: the molecular machinery. Crit Rev Eukaryot Gene Expr 3: 63-88, 1993.
57. Ramakrishnan R, DuBois DC, Almon RR, Pyszczynski NA, Jusko WJ. Fifth-generation model for corticosteroid pharmacodynamics: application to steady-state receptor down-regulation and enzyme induction patterns during seven-day continuous infusion of methylprednisolone in rats. J Pharmacokinet Pharmacodyn 29: 1-24, 2002.
58. Reilly DF, Westgate EJ, FitzGerald GA. Peripheral circadian clocks in the vasculature. Arterioscler Thromb Vasc Biol 27: 1694-1705, 2007.
59. Relogio A, Westermark PO, Wallach T, Schellenberg K, Kramer A, Herzel H. Tuning the mammalian circadian clock: robust synergy of two loops. PLoS Comput Biol 7: e1002309, 2011.
60. Reppert SM, Perlow MJ, Ungerleider LG, Mishkin M, Tamarkin L, Orloff DG, Hoffman HJ, Klein DC. Effects of damage to the suprachiasmatic area of the anterior hypothalamus on the daily melatonin and cortisol rhythms in the rhesus monkey. J Neurosci 1: 1414-1425, 1981.
61. Rusak B, Zucker I. Neural regulation of circadian rhythms. Physiol Rev 59: 449-526, 1979.
62. Scheff JD, Calvano SE, Lowry SF, Androulakis IP. Modeling the influence of circadian rhythms on the acute inflammatory response. J Theor Biol 264: 1068-1076, 2010.
63. Sephton S, Spiegel D. Circadian disruption in cancer: a neuroendocrineimmune pathway from stress to disease? Brain Behav Immun 17: 321-328, 2003.
64. Sephton SE, Sapolsky RM, Kraemer HC, Spiegel D. Diurnal cortisol rhythm as a predictor of breast cancer survival. J Natl Cancer Inst 92: 994-1000, 2000.
65. So AYL, Bernal TU, Pillsbury ML, Yamamoto KR, Feldman BJ. Glucocorticoid regulation of the circadian clock modulates glucose homeostasis. Proc Natl Acad Sci USA 106: 17582-17587, 2009.
66. Stratmann M, Schibler U. Properties, entrainment, and physiological functions of mammalian peripheral oscillators. J Biol Rhythms 21: 494-506, 2006.
67. Stricker J, Cookson S, Bennett MR, Mather WH, Tsimring LS, Hasty J. A fast, robust and tunable synthetic gene oscillator. Nature 456: 516-519, 2008.
68. Strogatz SH, Stewart I. Coupled oscillators and biological synchronization. Sci Am 269: 102-109, 1993.
69. Tass P, Rosenblum MG, Weule J, Kurths J, Pikovsky A, Volkmann J, Schnitzler A, Freund HJ. Detection of n:m phase locking from noisy data: application to magnetoencephalography. Phys Rev Lett 81: 3291-3294, 1998.
70. Touitou Y, Bogdan A, Levi F, Benavides M, Auzeby A. Disruption of the circadian patterns of serum cortisol in breast and ovarian cancer patients: relationships with tumour marker antigens. Br J Cancer 74: 1248-1252, 1996.
71. Ullner E, Buceta J, Diez-Noguera A, Garcia-Ojalvo J. Noise-induced coherence in multicellular circadian clocks. Biophys J 96: 3573-3581, 2009.
72. Welsh DK, Yoo SH, Liu AC, Takahashi JS, Kay SA. Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression. Curr Biol 14: 2289-2295, 2004.
73. Yamamoto T, Nakahata Y, Tanaka M, Yoshida M, Soma H, Shinohara K, Yasuda A, Mamine T, Takumi T. Acute physical stress elevates mouse period1 mRNA expression in mouse peripheral tissues via a glucocorticoid-responsive element. J Biol Chem 280: 42036-42043, 2005.
74. Yamazaki S, Numano R, Abe M, Hida A, Takahashi R, Ueda M, Block GD, Sakaki Y, Menaker M, Tei H. Resetting central and peripheral circadian oscillators in transgenic rats. Science 288: 682-685, 2000.
75. Yamazaki S, Straume M, Tei H, Sakaki Y, Menaker M, Block GD. Effects of aging on central and peripheral mammalian clocks. Proc Natl Acad Sci USA 99: 10801-10806, 2002.
76. Yao Z, DuBois DC, Almon RR, Jusko WJ. Modeling circadian rhythms of glucocorticoid receptor and glutamine synthetase expression in rat skeletal muscle. Pharm Res 23: 670-679, 2006.
77. Yoo SH, Yamazaki S, Lowrey PL, Shimomura K, Ko CH, Buhr ED, Siepka SM, Hong HK, Oh WJ, Yoo OJ, Menaker M, Takahashi JS. PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc Natl Acad Sci USA 101: 5339-5346, 2004.
78. Zvonic S, Ptitsyn AA, Conrad SA, Scott LK, Floyd ZE, Kilroy G, Wu X, Goh BC, Mynatt RL, Gimble JM. Characterization of peripheral circadian clocks in adipose tissues. Diabetes 55: 962-970, 2006.