Glucocorticoids and the circadian clock

Journal of Endocrinology

Volumn 200, Issue 1, 2009, Pages 3-22

  Dickmeis, Thomas ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ARGIPRESSIN; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CORTICOSTERONE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; CRYPTOCHROME; GLUCOCORTICOID; HEAT SHOCK PROTEIN; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MELANOCORTIN 2 RECEPTOR; OXYTOCIN; PER1 PROTEIN; PROTEIN BMAL1; RETINOIC ACID RECEPTOR; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TRANSCRIPTOME;

ADRENAL GLAND; AUTONOMIC NERVOUS SYSTEM; CIRCADIAN RHYTHM; HOMEOSTASIS; HORMONE RELEASE; HUMAN; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; HYPOTHALAMUS NUCLEUS; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; NEGATIVE FEEDBACK; NERVOUS SYSTEM; NEUROANATOMY; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; REVIEW; SIGNAL TRANSDUCTION; STRESS; SUPRACHIASMATIC NUCLEUS;

ADRENAL GLANDS; ANIMALS; BIOLOGICAL CLOCKS; CIRCADIAN RHYTHM; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HUMANS; HYPOTHALAMUS; NEUROSECRETORY SYSTEMS;

EID: 67449151670     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-08-0415     Document Type: Review

References (238)

1. Abdel-Malek ZA 2001 Melanocortin receptors: their functions and regulation by physiological agonists and antagonists. Cellular and Molecular Life Sciences 58 434-441.
2. Abe K, Kroning J, Greer MA & Critchlow V 1979 Effects of destruction of the suprachiasmatic nuclei on the circadian rhythms in plasma corticosterone, body temperature, feeding and plasma thyrotropin. Neuroendocrinology 29 119-131.
3. Abe M, Herzog ED, Yamazaki S, Straume M, Tei H, Sakaki Y, Menaker M & Block GD 2002 Circadian rhythms in isolated brain regions. Journal of Neuroscience 22 350-356.
4. Akhtar RA, Reddy AB, Maywood ES, Clayton JD, King VM, Smith AG, Gant TW, Hastings MH & Kyriacou CP 2002 Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus. Current Biology 12 540-550.
5. Almon RR, Yang E, Lai W, Androulakis IP, Ghimbovschi S, Hoffman EP, Jusko WJ & Dubois DC 2008 Relationships between circadian rhythms and modulation of gene expression by glucocorticoids in skeletal muscle. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 295 R1031-R1047.
6. Amir S & Robinson B 2006 Thyroidectomy alters the daily pattern of expression of the clock protein, PER2, in the oval nucleus of the bed nucleus of the stria terminalis and central nucleus of the amygdala in rats. Neuroscience Letters 407 254-257.
7. Amir S, Lamont EW, Robinson B & Stewart J 2004 A circadian rhythm in the expression of PERIOD2 protein reveals a novel SCN-controlled oscillator in the oval nucleus of the bed nucleus of the stria terminalis. Journal of Neuroscience 24 781-790.
8. Andrews RV 1971 Circadian rhythms in adrenal organ cultures. Gegenbaurs Morphologisches Jahrbuch 117 89-98.
9. Andrews RV & Folk GE Jr 1964 Circadian metabolic patterns in cultured hamster adrenal glands. Comparative Biochemistry and Physiology 11 393-409.
10. Antle MC & Silver R 2005 Orchestrating time: arrangements of the brain circadian clock. Trends in Neurosciences 28 145-151.
11. Antoni FA, Palkovits M, Makara GB, Linton EA, Lowry PJ & Kiss JZ 1983 Immunoreactive corticotropin-releasing hormone in the hypothalamoin-fundibular tract. Neuroendocrinology 36 415-423.
12. Arriza JL, Simerly RB, Swanson LW & Evans RM 1988 The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response. Neuron 1 887-900.
13. Aschoff J 1979 Circadian rhythms: general features and endocrinological aspects. In Endocrine Rhythms, pp 1-63. Ed. D Krieger. New York: Raven Press.
14. Atkinson HC, Wood SA, Kershaw YM, Bate E & Lightman SL 2006 Diurnal variation in the responsiveness of the hypothalamic-pituitary-adrenal axis of the male rat to noise stress. Journal of Neuroendocrinology 18 526-533.
15. Balsalobre A 2002 Clock genes in mammalian peripheral tissues. Cell and Tissue Research 309 193-199.
16. Balsalobre A, Damiola F & Schibler U 1998 A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell 93 929-937.
17. Balsalobre A, Brown SA, Marcacci L, Tronche F, Kellendonk C, Reichardt HM, Schutz G & Schibler U 2000 Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science 289 2344-2347.
18. Bao AM, Meynen G & Swaab DF 2008 The stress system in depression and neurodegeneration: focus on the human hypothalamus. Brain Research Reviews 57 531-553.
19. Berk ML & Finkelstein JA 1981 An autoradiographic determination of the efferent projections of the suprachiasmatic nucleus of the hypothalamus. Brain Research 226 1-13.
20. Berson DM 2007 Phototransduction in ganglion-cell photoreceptors. Pflügers Archiv 454 849-855.
21. Bertolucci C, Cavallari N, Colognesi I, Aguzzi J, Chen Z, Caruso P, Fo A, Tosini G, Bernardi F & Pinotti M 2008 Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators. Molecular and Cellular Biology 28 3070-3075.
22. Bittman EL, Doherty L, Huang L & Paroskie A 2003 Period gene expression in mouse endocrine tissues. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 285 R561-R569.
23. Bjarnason GA & Jordan R 2000 Circadian variation of cell proliferation and cell cycle protein expression in man: clinical implications. Progress in Cell Cycle Research 4 193-206.
24. Bornstein SR, Ehrhart-Bornstein M, Scherbaum WA, Pfeiffer EF & Holst JJ 1990 Effects of splanchnic nerve stimulation on the adrenal cortex may be mediated by chromaffin cells in a paracrine manner. Endocrinology 127 900-906.
25. Bornstein SR, Engeland WC, Ehrhart-Bornstein M & Herman JP 2008 Dissociation of ACTH and glucocorticoids. Trends in Endocrinology and Metabolism 19 175-180.
26. Bozek K, Kielbasa SM, Kramer A & Herzel H 2007 Promoter analysis of mammalian clock controlled genes. Genome Informatics 18 65-74.
27. Brown MR & Fisher LA 1986 Glucocorticoid suppression of the sympathetic nervous system and adrenal medulla. Life Sciences 39 1003-1012.
28. Brown SA, Zumbrunn G, Fleury-Olela F, Preitner N & Schibler U 2002 Rhythms of mammalian body temperature can sustain peripheral circadian clocks. Current Biology 12 1574-1583.
29. Brunner M & Schafmeier T 2006 Transcriptional and post-transcriptional regulation of the circadian clock of cyanobacteria and Neurospora. Genes and Development 20 1061-1074.
30. Brunner M, Simons MJ & Merrow M 2008 Lego clocks: building a clock from parts. Genes and Development 22 1422-1426.
31. Buijs RM & Escobar C 2007 Corticosterone and activity: the long arms of the clock talk back. Endocrinology 148 5162-5164.
32. Buijs RM & Kalsbeek A 2001 Hypothalamic integration of central and peripheral clocks. Nature Reviews. Neuroscience 2 521-526.
33. Buijs RM, Kalsbeek A, van der Woude TP, van Heerikhuize JJ & Shinn S 1993a Suprachiasmatic nucleus lesion increases corticosterone secretion. American Journal of Physiology 264 R1186-R1192.
34. Buijs RM, Markman M, Nunes-Cardoso B, Hou YX & Shinn S 1993b Projections of the suprachiasmatic nucleus to stress-related areas in the rat hypothalamus: a light and electron microscopic study. Journal of Comparative Neurology 335 42-54.
35. Buijs RM, Wortel J, Van Heerikhuize JJ, Feenstra MG, Ter Horst GJ, Romijn HJ & Kalsbeek A 1999 Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway. European Journal of Neuroscience 11 1535-1544.
36. Buijs RM, van Eden CG, Goncharuk VD & Kalsbeek A 2003 The biological clock tunes the organs of the body: timing by hormones and the autonomic nervous system. Journal of Endocrinology 177 17-26.
37. Buren J, Bergstrom SA, Loh E, Soderstrom I, Olsson T & Mattsson C 2007 Hippocampal 11beta-hydroxysteroid dehydrogenase type 1 messenger ribonucleic acid expression has a diurnal variability that is lost in the obese Zucker rat. Endocrinology 148 2716-2722.
38. Busino L, Bassermann F, Maiolica A, Lee C, Nolan PM, Godinho SI, Draetta GF & Pagano M 2007 SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. Science 316 900-904.
39. Cailotto C, La Fleur SE, Van Heijningen C, Wortel J, Kalsbeek A, Feenstra M, Pevet P & Buijs RM 2005 The suprachiasmatic nucleus controls the daily variation of plasma glucose via the autonomic output to the liver: are the clock genes involved? European Journal of Neuroscience 22 2531-2540.
40. Cailotto C, van Heijningen C, van der Vliet J, van der Plasse G, Habold C, Kalsbeek A, Pevet P & Buijs RM 2008 Daily rhythms in metabolic liver enzymes and plasma glucose require a balance in the autonomic output to the liver. Endocrinology 149 1914-1925.
41. Carnes M, Kalin NH, Lent SJ, Barksdale CM & Brownfield MS 1988 Pulsatile ACTH secretion: variation with time of day and relationship to cortisol. Peptides 9 325-331.
42. Carnes M, Lent S, Feyzi J & Hazel D 1989 Plasma adrenocorticotropic hormone in the rat demonstrates three different rhythms within 24 h. Neuroendocrinology 50 17-25.
43. Carr AJ & Whitmore D 2005 Imaging of single light-responsive clock cells reveals fluctuating free-running periods. Nature Cell Biology 7 319-321.
44. Carroll T, Raff H & Findling JW 2008 Late-night salivary cortisol measurement in the diagnosis of Cushing's syndrome. Nature Clinical Practice. Endocrinology & Metabolism 4 344-350.
45. Cascio CS, Shinsako J & Dallman MF 1987 The suprachiasmatic nuclei stimulate evening ACTH secretion in the rat. Brain Research 423 173-178.
46. Van Cauter E 1990 Diurnal and ultradian rhythms in human endocrine function: a minireview. Hormone Research 34 45-53.
47. Chapman KE & Seckl JR 2008 11β-HSD1, inflammation, metabolic disease and age-related cognitive (dys)function. Neurochemistry Research 33 624-636.
48. Cheifetz PN 1971 The daily rhythm of the secretion of corticotrophin and corticosterone in rats and mice. Journal of Endocrinology 49 xi-xii.
49. Chrousos GP 1998 Ultradian, circadian, and stress-related hypothalamic-pituitary-adrenal axis activity - a dynamic digital-to-analog modulation. Endocrinology 139 437-440.
50. Claridge-Chang A, Wijnen H, Naef F, Boothroyd C, Rajewsky N & Young MW2001 Circadian regulation of gene expression systems in the Drosophila head. Neuron 32 657-671.
51. Conway-Campbell BL, McKenna MA, Wiles CC, Atkinson HC, de Kloet ER & Lightman SL 2007 Proteasome-dependent down-regulation of activated nuclear hippocampal glucocorticoid receptors determines dynamic responses to corticosterone. Endocrinology 148 5470-5477.
52. Dallman MF, Engeland WC, Rose JC, Wilkinson CW, Shinsako J & Siedenburg F 1978 Nycthemeral rhythm in adrenal responsiveness to ACTH. American Journal of Physiology 235 R210-R218.
53. Dallman MF, Strack AM, Akana SF, Bradbury MJ, Hanson ES, Scribner KA & Smith M 1993 Feast and famine: critical role of glucocorticoids with insulin in daily energy flow. Frontiers in Neuroendocrinology 14 303-347.
54. Damiola F, Le Minh N, Preitner N, Kornmann B, Fleury-Olela F & Schibler U 2000 Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes and Development 14 2950-2961.
55. Darnaudery M & Maccari S 2008 Epigenetic programming of the stress response in male and female rats by prenatal restraint stress. Brain Research Reviews 57 571-585.
56. Davidson AJ 2006 Search for the feeding-entrainable circadian oscillator: a complex proposition. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 290 R1524-R1526.
57. Debruyne JP, Noton E, Lambert CM, Maywood ES, Weaver DR & Reppert SM 2006 A clock shock: mouse CLOCK is not required for circadian oscillator function. Neuron 50 465-477.
58. DeBruyne JP, Weaver DR & Reppert SM 2007a Peripheral circadian oscillators require CLOCK. Current Biology 17 R538-R539.
59. DeBruyne JP, Weaver DR & Reppert SM 2007b CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock. Nature Neuroscience 10 543-545.
60. Dekens MP, Santoriello C, Vallone D, Grassi G, Whitmore D & Foulkes NS 2003 Light regulates the cell cycle in zebrafish. Current Biology 13 2051-2057.
61. Dickmeis T, Lahiri K, Nica G, Vallone D, Santoriello C, Neumann CJ, Hammerschmidt M & Foulkes NS 2007 Glucocorticoids play a key role in circadian cell cycle rhythms. PLoS Biology 5 e78.
62. Dijkstra I, Binnekade R & Tilders FJ 1996 Diurnal variation in resting levels of corticosterone is not mediated by variation in adrenal responsiveness to adrenocorticotropin but involves splanchnic nerve integrity. Endocrinology 137 540-547.
63. Dudley CA, Erbel-Sieler C, Estill SJ, Reick M, Franken P, Pitts S & McKnight SL 2003 Altered patterns of sleep and behavioral adaptability in NPAS2deficient mice. Science 301 379-383.
64. Duez H & Staels B 2008 The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism. Diabetes & Vascular Disease Research 5 82-88.
65. Duffield GE 2003 DNA microarray analyses of circadian timing: the genomic basis of biological time. Journal of Neuroendocrinology 15 991-1002.
66. Dunlap J, Loros J & DeCoursey P 2004 Chronobiology., Sunderland: Sinauer Associates.
67. Ehrhart-Bornstein M, Hinson JP, Bornstein SR, Scherbaum WA & Vinson GP 1998 Intraadrenal interactions in the regulation of adrenocortical steroidogenesis. Endocrine Reviews 19 101-143.
68. Engeland WC & Arnhold MM 2005 Neural circuitry in the regulation of adrenal corticosterone rhythmicity. Endocrine 28 325-332.
69. Engler D, Pham T, Fullerton MJ, Ooi G, Funder JW & Clarke IJ 1989 Studies of the secretion of corticotropin-releasing factor and arginine vasopressin into the hypophysial-portal circulation of the conscious sheep. I. Effect of an audiovisual stimulus and insulin-induced hypoglycemia. Neuroendocrinology 49 367-381.
70. Fahrenkrug J, Hannibal J & Georg B 2008 Diurnal rhythmicity of the canonical clock genes Per1, Per2 and Bmal1 in the rat adrenal gland is unaltered after hypophysectomy. Journal of Neuroendocrinology 20 323-329.
71. Falvey E, Fleury-Olela F & Schibler U 1995 The rat hepatic leukemia factor (HLF) gene encodes two transcriptional activators with distinct circadian rhythms, tissue distributions and target preferences. EMBO Journal 14 4307-4317.
72. Feillet CA, Ripperger JA, Magnone MC, Dulloo A, Albrecht U & Challet E 2006 Lack of food anticipation in Per2 mutant mice. Current Biology 16 2016-2022.
73. Ferrari E, Casarotti D, Muzzoni B, Albertelli N, Cravello L, Fioravanti M, Solerte SB & Magri F 2001 Age-related changes of the adrenal secretory pattern: possible role in pathological brain aging. Brain Research. Brain Research Reviews 37 294-300.
74. Fonjallaz P, Ossipow V, Wanner G & Schibler U 1996 The two PAR leucine zipper proteins, TEF and DBP, display similar circadian and tissue-specific expression, but have different target promoter preferences. EMBO Journal 15 351-362.
75. Fuller PM, Lu J & Saper CB 2008 Differential rescue of light- and food-entrainable circadian rhythms. Science 320 1074-1077.
76. Furay AR, Murphy EK, Mattson MP, Guo Z & Herman JP 2006 Region-specific regulation of glucocorticoid receptor/HSP90 expression and interaction in brain. Journal of Neurochemistry 98 1176-1184.
77. Gallego M & Virshup DM 2007 Post-translational modifications regulate the ticking of the circadian clock. Nature Reviews. Molecular Cell Biology 8 139-148.
78. Van Gelder RN, Bae H, Palazzolo MJ & Krasnow MA 1995 Extent and character of circadian gene expression in Drosophila melanogaster: identification of twenty oscillating mRNAs in the fly head. Current Biology 5 1424-1436.
79. Godinho SI, Maywood ES, Shaw L, Tucci V, Barnard AR, Busino L, Pagano M, Kendall R, Quwailid MM, Romero MR et al. 2007 The after-hours mutant reveals a role for Fbx13 in determining mammalian circadian period. Science 316 897-900.
80. Gooley JJ & Saper CB 2007 Is food-directed behavior an appropriate measure of circadian entrainment to restricted daytime feeding? Journal of Biological Rhythms 22 479-483 (discussion 484-487).
81. Gooley JJ, Schomer A & Saper CB 2006 The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms. Nature Neuroscience 9 398-407.
82. Grad I & Picard D 2007 The glucocorticoid responses are shaped by molecular chaperones. Molecular and Cellular Endocrinology 275 2-12.
83. Graham ES, Littlewood P, Turnbull Y, Mercer JG, Morgan PJ & Barrett P 2005 Neuromedin-U is regulated by the circadian clock in the SCN of the mouse. European Journal of Neuroscience 21 814-819.
84. Gudmundsson A & Carnes M 1997 Pulsatile adrenocorticotropic hormone: an overview. Biological Psychiatry 41 342-365.
85. Gummow BM, Scheys JO, Cancelli VR & Hammer GD 2006 Reciprocal regulation of a glucocorticoid receptor-steroidogenic factor-1 transcription complex on the Dax-1 promoter by glucocorticoids and adrenocorticotropic hormone in the adrenal cortex. Molecular Endocrinology 20 2711-2723.
86. Hankins MW, Peirson SN & Foster RG 2008 Melanopsin: an exciting photopigment. Trends in Neurosciences 31 27-36.
87. Hara R, Wan K, Wakamatsu H, Aida R, Moriya T, Akiyama M & Shibata S 2001 Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus. Genes to Cells 6 269-278.
88. De Haro L & Panda S 2006 Systems biology of circadian rhythms: an outlook. Journal of Biological Rhythms 21 507-518.
89. Harris HJ, Kotelevtsev Y, Mullins JJ, Seckl JR & Holmes MC 2001 Intracellular regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase (11beta-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: analysis of 11beta-HSD-1-deficient mice. Endocrinology 142 114-120.
90. Hastings M, O'Neill JS & Maywood ES 2007 Circadian clocks: regulators of endocrine and metabolic rhythms. Journal of Endocrinology 195 187-198.
91. Haus E 2007 Chronobiology in the endocrine system. Advanced Drug Delivery Reviews 59 985-1014.
92. Herman JP, Watson SJ, Chao HM, Coirini H & McEwen BS 1993 Diurnal regulation of glucocorticoid receptor and mineralocorticoid receptor mRNAs in rat hippocampus. Molecular and Cellular Neurosciences 4 181-190.
93. Herzog ED & Muglia LJ 2006 You are when you eat. Nature Neuroscience 9 300-302.
94. Hiroshige T, Honma K & Honma S 1991 SCN-independent circadian oscillators in the rat. Brain Research Bulletin 27 441-445.
95. Holaday JW, Martinez HM & Natelson BH 1977 Synchronized ultradian cortisol rhythms in monkeys: persistence during corticotropin infusion. Science 198 56-58.
96. ter Horst GJ & Luiten PG 1986 The projections of the dorsomedial hypothalamic nucleus in the rat. Brain Research Bulletin 16 231-248.
97. Hunt T & Sassone-Corsi P 2007 Riding tandem: circadian clocks and the cell cycle. Cell 129 461-464.
98. Iijima M, Yamaguchi S, van der Horst GT, Bonnefont X, Okamura H & Shibata S 2005 Altered food-anticipatory activity rhythm in cryptochrome-deficient mice. Neuroscience Research 52 166-173.
99. Irvine CH & Alexander SL 1994 Factors affecting the circadian rhythm in plasma cortisol concentrations in the horse. Domestic Animal Endocrinology 11 227-238.
100. Ishida A, Mutoh T, Ueyama T, Bando H, Masubuchi S, Nakahara D, Tsujimoto G & Okamura H 2005 Light activates the adrenal gland: timing of gene expression and glucocorticoid release. Cell Metabolism 2 297-307.
101. Jacobson L 2005 Hypothalamic-pituitary-adrenocortical axis regulation. Endocrinology and Metabolism Clinics of North America 34 271-292 (vii).
102. Jasper MS & Engeland WC 1991 Synchronous ultradian rhythms in adrenocortical secretion detected by microdialysis in awake rats. American Journal of Physiology 261 R1257-R1268.
103. Joels M, Karst H, DeRijk R & de Kloet ER 2008 The coming out of the brain mineralocorticoid receptor. Trends in Neurosciences 31 1-7.
104. Kadener S, Menet JS, Schoer R & Rosbash M 2008 Circadian transcription contributes to core period determination in Drosophila. PLoS Biology 6 e119.
105. Kalsbeek A & Buijs RM 2002 Output pathways of the mammalian suprachiasmatic nucleus: coding circadian time by transmitter selection and specific targeting. Cell and Tissue Research 309 109-118.
106. Kalsbeek A, Buijs RM, van Heerikhuize JJ, Arts M & van der Woude TP 1992 Vasopressin-containing neurons of the suprachiasmatic nuclei inhibit corticosterone release. Brain Research 580 62-67.
107. Kalsbeek A, Buijs RM, Engelmann M, Wotjak CT & Landgraf R 1995 In vivo measurement of a diurnal variation in vasopressin release in the rat suprachiasmatic nucleus. Brain Research 682 75-82.
108. Kalsbeek A, van der Vliet J & Buijs RM 1996a Decrease of endogenous vasopressin release necessary for expression of the circadian rise in plasma corticosterone: a reverse microdialysis study. Journal of Neuroendocrinology 8 299-307.
109. Kalsbeek A, van Heerikhuize JJ, Wortel J & Buijs RM 1996b A diurnal rhythm of stimulatory input to the hypothalamo-pituitary-adrenal system as revealed by timed intrahypothalamic administration of the vasopressin V1 antagonist. Journal of Neuroscience 16 5555-5565.
110. Kalsbeek A, Ruiter M, La Fleur SE, Van Heijningen C & Buijs RM 2003 The diurnal modulation of hormonal responses in the rat varies with different stimuli. Journal of Neuroendocrinology 15 1144-1155.
111. Kalsbeek A, Palm IF, La Fleur SE, Scheer FA, Perreau-Lenz S, Ruiter M, Kreier F, Cailotto C & Buijs RM 2006 SCN outputs and the hypothalamic balance of life. Journal of Biological Rhythms 21 458-469.
112. Kalsbeek A, Verhagen LA, Schalij I, Foppen E, Saboureau M, Bothorel B, Buijs RM & Pevet P 2008 Opposite actions of hypothalamic vasopressin on circadian corticosterone rhythm in nocturnal versus diurnal species. European Journal of Neuroscience 27 818-827.
113. Kaneko M, Hernandez-Borsetti N & Cahill GM 2006 Diversity of zebrafish peripheral oscillators revealed by luciferase reporting. PNAS 103 14614-14619.
114. Kassahn KS, Crozier RH, Ward AC, Stone G & Caley MJ 2007 From transcriptome to biological function: environmental stress in an ectothermic vertebrate, the coral reeffish Pomacentrus moluccensis. BMC Genomics 8 358.
115. Kassel O & Herrlich P 2007 Crosstalk between the glucocorticoid receptor and other transcription factors: molecular aspects. Molecular and Cellular Endocrinology 275 13-29.
116. Keegan KP, Pradhan S, Wang JP & Allada R 2007 Meta-analysis of Drosophila circadian microarray studies identifies a novel set of rhythmically expressed genes. PLoS Computational Biology 3 e208.
117. Kennaway DJ, Owens JA, Voultsios A & Varcoe TJ 2006 Functional central rhythmicity and light entrainment, but not liver and muscle rhythmicity, are Clock independent. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 291 R1172-R1180.
118. Kitayama Y, Nishiwaki T, Terauchi K & Kondo T 2008 Dual KaiC-based oscillations constitute the circadian system of cyanobacteria. Genes and Development 22 1513-1521.
119. Klein DC, Moore RY & Reppert SM 1991 Suprachiasmatic Nucleus - The Mind's Clock. New York: Oxford University Press.
120. Klemcke HG, Nienaber JA & Hahn GL 1989 Plasma adrenocorticotropic hormone and cortisol in pigs: effects of time of day on basal and stressor-altered concentrations. Proceedings of the Society for Experimental Biology and Medicine 190 42-53.
121. Knutti D, Kaul A & Kralli A 2000 A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen. Molecular and Cellular Biology 20 2411-2422.
122. Ko CH & Takahashi JS 2006 Molecular components of the mammalian circadian clock. Human Molecular Genetics 15 R271-R277.
123. Kornmann B, Schaad O, Bujard H, Takahashi JS & Schibler U 2007 System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock. PLoS Biology 5 e34.
124. Krieger DT, Hauser H & Krey LC 1977 Suprachiasmatic nuclear lesions do not abolish food-shifted circadian adrenal and temperature rhythmicity. Science 197 398-399.
125. Lamont EW, Robinson B, Stewart J & Amir S 2005 The central and basolateral nuclei of the amygdala exhibit opposite diurnal rhythms of expression of the clock protein Period2. PNAS 102 4180-4184.
126. Landry GJ & Mistlberger RE 2007 Food entrainment: methodological issues. Journal of Biological Rhythms 22 484-487.
127. Landry GJ, Simon MM, Webb IC & Mistlberger RE 2006 Persistence of a behavioral food-anticipatory circadian rhythm following dorsomedial hypothalamic ablation in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 290 R1527-R1534.
128. Landry GJ, Yamakawa GR, Webb IC, Mear RJ & Mistlberger RE 2007 The dorsomedial hypothalamic nucleus is not necessary for the expression of circadian food-anticipatory activity in rats. Journal of Biological Rhythms 22 467-478.
129. Lefcourt AM, Bitman J, Kahl S & Wood DL 1993 Circadian and ultradian rhythms of peripheral cortisol concentrations in lactating dairy cows. Journal of Dairy Science 76 2607-2612.
130. Lemos DR, Downs JL & Urbanski HF 2006 Twenty-four-hour rhythmic gene expression in the rhesus macaque adrenal gland. Molecular Endocrinology 20 1164-1176.
131. Lightman SL 2008 The neuroendocrinology of stress: a never ending story. Journal of Neuroendocrinology 20 880-884.
132. Lightman SL, Wiles CC, Atkinson HC, Henley DE, Russell GM, Leendertz JA, McKenna MA, Spiga F, Wood SA & Conway-Campbell BL 2008 The significance of glucocorticoid pulsatility. European Journal of Pharmacology 583 255-262.
133. Lincoln GA, Almeida OF, Klandorf H & Cunningham RA 1982 Hourly fluctuations in the blood levels of melatonin, prolactin, luteinizing hormone, follicle-stimulating hormone, testosterone, tri-iodothyronine, thyroxine and cortisol in rams under artificial photoperiods, and the effects of cranial sympathectomy. Journal of Endocrinology 92 237-250.
134. Liu Y, Tsinoremas NF, Johnson CH, Lebedeva NV, Golden SS, Ishiura M & Kondo T 1995 Circadian orchestration of gene expression in cyanobacteria. Genes and Development 9 1469-1478.
135. Liu C, Li S, Liu T, Borjigin J & Lin JD 2007 Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism. Nature 447 477-481
136. Loudon AS, Wayne NL, Krieg R, Iranmanesh A, Veldhuis JD & Menaker M 1994 Ultradian endocrine rhythms are altered by a circadian mutation in the Syrian hamster. Endocrinology 135 712-718.
137. Lowry CA 2002 Functional subsets of serotonergic neurones: implications for control of the hypothalamic-pituitary-adrenal axis. Journal of Neuroendocrinology 14 911-923.
138. Mackey SR & Golden SS 2007 Winding up the cyanobacterial circadian clock. Trends in Microbiology 15 381-388.
139. Malek ZS, Sage D, Pevet P & Raison S 2007 Daily rhythm of tryptophan hydroxylase-2 messenger ribonucleic acid within raphe neurons is induced by corticoid daily surge and modulated by enhanced locomotor activity. Endocrinology 148 5165-5172.
140. Matsuo T, Yamaguchi S, Mitsui S, Emi A, Shimoda F & Okamura H 2003 Control mechanism of the circadian clock for timing of cell division in vivo. Science 302 255-259.
141. Maywood ES, O'Neill JS, Chesham JE & Hastings MH 2007 Minireview: the circadian clockwork of the suprachiasmatic nuclei - analysis of a cellular oscillator that drives endocrine rhythms. Endocrinology 148 5624-5634.
142. McDonald MJ & Rosbash M 2001 Microarray analysis and organization of circadian gene expression in Drosophila. Cell 107 567-578.
143. Meier AH 1976 Daily variation in concentration of plasma corticosteroid in hypophysectomized rats. Endocrinology 98 1475-1479.
144. Menaker M, Moreira LF & Tosini G 1997 Evolution of circadian organization in vertebrates. Brazilian Journal of Medical and Biological Research 30 305-313.
145. Mendoza J 2007 Circadian clocks: setting time by food. Journal of Neuroendocrinology 19 127-137.
146. Meyer-Bernstein EL & Morin LP 1999 Electrical stimulation of the median or dorsal raphe nuclei reduces light-induced FOS protein in the suprachiasmatic nucleus and causes circadian activity rhythm phase shifts. Neuroscience 92 267-279.
147. Meyer-Bernstein EL, Jetton AE, Matsumoto SI, Markuns JF, Lehman MN & Bittman EL 1999 Effects of suprachiasmatic transplants on circadian rhythms of neuroendocrine function in golden hamsters. Endocrinology 140 207-218.
148. Mieda M, Williams SC, Richardson JA, Tanaka K & Yanagisawa M 2006 The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemaker. PNAS 103 12150-12155.
149. Le Minh N, Damiola F, Tronche F, Schutz G & Schibler U 2001 Glucocorticoid hormones inhibit food-induced phase-shifting of peripheral circadian oscillators. EMBO Journal 20 7128-7136.
150. Mistlberger RE 1994 Circadian food-anticipatory activity: formal models and physiological mechanisms. Neuroscience and Biobehavioral Reviews 18 171-195.
151. Moore RY & Eichler VB 1972 Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat. Brain Research 42 201-206.
152. Mori T & Johnson CH 2000 Circadian control of cell division in unicellular organisms. Progress in Cell Cycle Research 4 185-192.
153. Morin LP 1999 Serotonin and the regulation of mammalian circadian rhythmicity. Annals of Medicine 31 12-33.
154. Nagoshi E, Saini C, Bauer C, Laroche T, Naef F & Schibler U 2004 Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cells. Cell 119 693-705.
155. Nakajima M, Imai K, Ito H, Nishiwaki T, Murayama Y, Iwasaki H, Oyama T & Kondo T 2005 Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro. Science 308 414-415.
156. Niijima A, Nagai K, Nagai N & Nakagawa H 1992 Light enhances sympathetic and suppresses vagal outflows and lesions including the suprachiasmatic nucleus eliminate these changes in rats. Journal of the Autonomic Nervous System 40 155-160.
157. Niijima A, Nagai K, Nagai N & Akagawa H 1993 Effects of light stimulation on the activity of the autonomic nerves in anesthetized rats. Physiology and Behavior 54 555-561.
158. Norris DO 2007 Vertebrate Endocrinology. 4 edn, Burlington, San Diego, London: Elsevier Academic Press.
159. Oishi K, Fukui H & Ishida N 2000 Rhythmic expression of BMAL1 mRNA is altered in Clock mutant mice: differential regulation in the suprachiasmatic nucleus and peripheral tissues. Biochemical and Biophysical Research Communications 268 164-171.
160. Oishi K, Amagai N, Shirai H, Kadota K, Ohkura N & Ishida N 2005 Genome-wide expression analysis reveals 100 adrenal gland-dependent circadian genes in the mouse liver. DNA Research 12 191-202.
161. Oster H, Damerow S, Hut RA & Eichele G 2006a Transcriptional profiling in the adrenal gland reveals circadian regulation of hormone biosynthesis genes and nucleosome assembly genes. Journal of Biological Rhythms 21 350-361.
162. Oster H, Damerow S, Kiessling S, Jakubcakova V, Abraham D, Tian J, Hoffmann MW & Eichele G 2006b The circadian rhythm of glucocorticoids is regulated by a gating mechanism residing in the adrenal cortical clock. Cell Metabolism 4 163-173.
163. Ottenweller JE & Meier AH 1982 Adrenal innervation may be an extrapituitary mechanism able to regulate adrenocortical rhythmicity in rats. Endocrinology 111 1334-1338.
164. Panda S, Antoch M, Miller B, Su A, Schook A, Straume M, Schultz P, Kay S, Takahashi J & Hogenesch J 2002 Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 109 307-320.
165. Pasquali R, Vicennati V, Cacciari M & Pagotto U 2006 The hypothalamic-pituitary-adrenal axis activity in obesity and the metabolic syndrome. Annals of the New York Academy of Sciences 1083 111-128.
166. Paterson JM, Holmes MC, Kenyon CJ, Carter R, Mullins JJ & Seckl JR 2007 Liver-selective transgene rescue of hypothalamic-pituitary-adrenal axis dysfunction in 11beta-hydroxysteroid dehydrogenase type 1-deficient mice. Endocrinology 148 961-966.
167. Payne AH & Hales DB 2004 Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocrine Reviews 25 947-970.
168. Pecoraro N, Dallman MF, Warne JP, Ginsberg AB, Laugero KD, la Fleur SE, Houshyar H, Gomez F, Bhargava A & Akana SF 2006 From Malthus to motive: how the HPA axis engineers the phenotype, yoking needs towants. Progress in Neurobiology 79 247-340.
169. Perlow MJ, Reppert SM, Boyar RM & Klein DC 1981 Daily rhythms in cortisol and melatonin in primate cerebrospinal fluid. Effects of constant light and dark. Neuroendocrinology 32 193-196.
170. Perrin JS, Segall LA, Harbour VL, Woodside B & Amir S 2006 The expression of the clock protein PER2 in the limbic forebrain is modulated by the estrous cycle. PNAS 103 5591-5596.
171. Pitts S, Perone E & Silver R 2003 Food-entrained circadian rhythms are sustained in arrhythmic Clk/Clk mutant mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 285 R57-R67.
172. Reddy AB & Maywood ES 2007 Circadian rhythms: per2bations in the liver clock. Current Biology 17 R292-R294.
173. Reddy AB, Wong GK, O'Neill J, Maywood ES & Hastings MH 2005 Circadian clocks: neural and peripheral pacemakers that impact upon the cell
174. Reddy AB, Karp NA, Maywood ES, Sage EA, Deery M, O'Neill JS, Wong GKY, Chesham J, Odell M, Lilley KS et al. 2006 Circadian orchestration of the hepatic proteome. Current Biology 16 1107-1115.
175. Reddy AB, Maywood ES, Karp NA, King VM, Inoue Y, Gonzalez FJ, Lilley KS, Kyriacou CP & Hastings MH 2007 Glucocorticoid signaling synchronizes the liver circadian transcriptome. Hepatology 45 1478-1488.
176. Reick M, Garcia JA, Dudley C & McKnight SL 2001 NPAS2: an analog of clock operative in the mammalian forebrain. Science 293 506-509.
177. Reinke H, Saini C, Fleury-Olela F, Dibner C, Benjamin IJ & Schibler U 2008 Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor. Genes and Development 22 331-345.
178. Remacle C, Dumortier O, Bol V, Goosse K, Romanus P, Theys N, Bouckenooghe T & Reusens B 2007 Intrauterine programming of the endocrine pancreas. Diabetes, Obesity and Metabolism 9 (Suppl 2) 196-209.
179. Renn SC, Park JH, Rosbash M, Hall JC & Taghert PH 1999 A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila. Cell 99 791-802.
180. Reppert SM, Artman HG, Swaminathan S & Fisher DA 1981 Vasopressin exhibits a rhythmic daily pattern in cerebrospinal fluid but not in blood. Science 213 1256-1257.
181. Reyes TM, Walker JR, DeCino C, Hogenesch JB & Sawchenko PE 2003 Categorically distinct acute stressors elicit dissimilar transcriptional profiles in the paraventricular nucleus of the hypothalamus. Journal of Neuroscience 23 5607-5616.
182. Roenneberg T & Merrow M 2002 'What watch?...such much!' complexity and evolution of circadian clocks Cell and Tissue Research 309 3-9.
183. Rosato E, Tauber E & Kyriacou CP 2006 Molecular genetics of the fruit-fly circadian clock. European Journal of Human Genetics 14 729-738.
184. Saeb-Parsy K, Lombardelli S, Khan FZ, McDowall K, Au-Yong IT & Dyball RE 2000 Neural connections of hypothalamic neuroendocrine nuclei in the rat. Journal of Neuroendocrinology 12 635-648.
185. Sage D, Maurel D & Bosler O 2001 Involvement of the suprachiasmatic nucleus in diurnal ACTH and corticosterone responsiveness to stress. American Journal of Physiology. Endocrinology and Metabolism 280 E260-E269.
186. Sage D, Maurel D & Bosler O 2002 Corticosterone-dependent driving influence of the suprachiasmatic nucleus on adrenal sensitivity to ACTH. American Journal of Physiology. Endocrinology and Metabolism 282 E458-E465.
187. Sage D, Ganem J, Guillaumond F, Laforge-Anglade G, Francois-Bellan AM, Bosler O & Becquet D 2004 Influence of the corticosterone rhythm on photic entrainment of locomotor activity in rats. Journal of Biological Rhythms 19 144-156.
188. Saper CB, Lu J, Chou TC & Gooley J 2005 The hypothalamic integrator for circadian rhythms. Trends in Neurosciences 28 152-157.
189. Sarnyai Z, Veldhuis JD, Mello NK, Mendelson JH, Eros-Sarnyai M, Mercer G, Gelles H & Kelly M 1995 The concordance of pulsatile ultradian release of adrenocorticotropin and cortisol in male rhesus monkeys. Journal of Clinical Endocrinology and Metabolism 80 54-59.
190. Sato TK, Yamada RG, Ukai H, Baggs JE, Miraglia LJ, Kobayashi TJ, Welsh DK, Kay SA, Ueda HR & Hogenesch JB 2006 Feedback repression is required for mammalian circadian clock function. Nature Genetics 38 312-319.
191. Sawchenko PE, Swanson LW & Vale WW 1984a Co-expression of corticotropin-releasing factor and vasopressin immunoreactivity in parvocellular neurosecretory neurons of the adrenalectomized rat. PNAS 81 1883-1887.
192. Sawchenko PE, Swanson LW & Vale WW 1984b Corticotropin-releasing factor: co-expression within distinct subsets of oxytocin-, vasopressin-, and neurotensin-immunoreactive neurons in the hypothalamus of the male rat. Journal of Neuroscience 4 1118-1129.
193. Schibler U & Sassone-Corsi P 2002 A web of circadian pacemakers. Cell 111 919-922.
194. Seckl JR 2008 Glucocorticoids, developmental 'programming' and the risk of affective dysfunction. Progress in Brain Research 167 17-34.
195. Segall LA, Perrin JS, Walker CD, Stewart J & Amir S 2006 Glucocorticoid rhythms control the rhythm of expression of the clock protein, Period2, in oval nucleus of the bed nucleus of the stria terminalis and central nucleus of the amygdala in rats. Neuroscience 140 753-757.
196. Siepka SM, Yoo SH, Park J, Song W, Kumar V, Hu Y, Lee C & Takahashi JS 2007 Circadian mutant overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression. Cell 129 1011-1023.
197. Srivastava AK & Meier AH 1972 Daily variation in concentration of cortisol in plasma in intact and hypophysectomized gulf killifish. Science 177 185-187.
198. Stahn C, Lowenberg M, Hommes DW & Buttgereit F 2007 Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists. Molecular and Cellular Endocrinology 275 71-78.
199. Stephan FK 2002 The 'other' circadian system: food as a Zeitgeber. Journal of Biological Rhythms 17 284-292.
200. Stephan FK, Berkley KJ & Moss RL 1981 Efferent connections of the rat suprachiasmatic nucleus. Neuroscience 6 2625-2641.
201. Stocco DM, Wang X, Jo Y & Manna PR 2005 Multiple signaling pathways regulating steroidogenesis and steroidogenic acute regulatory protein expression: more complicated than we thought. Molecular Endocrinology 19 2647-2659.
202. Stokkan KA, Yamazaki S, Tei H, Sakaki Y & Menaker M 2001 Entrainment of the circadian clock in the liver by feeding. Science 291 490-493.
203. Storch KF, Lipan O, Leykin I, Viswanathan N, Davis FC,Wong WH & Weitz CJ 2002 Extensive and divergent circadian gene expression in liver and heart. Nature 417 78-83.
204. Storch KF, Paz C, Signorovitch J, Raviola E, Pawlyk B, Li T & Weitz CJ 2007 Intrinsic circadian clock of the mammalian retina: importance for retinal processing of visual information. Cell 130 730-741.
205. Swanson LW, Sawchenko PE, Rivier J & Vale WW 1983 Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: an immunohistochemical study. Neuroendocrinology 36 165-186.
206. Szafarczyk A, Ixart G, Malaval F, Nouguier-Soule J & Assenmacher I 1979 Effects of lesions of the suprachiasmatic nuclei and of p-chlorophenylalanine on the circadian rhythms of adrenocorticotrophic hormone and corticosterone in the plasma, and on locomotor activity of rats. Journal of Endocrinology 83 1-16.
207. Tapp WN, Holaday JW & Natelson BH 1984 Ultradian glucocorticoid rhythms in monkeys and rats continue during stress. American Journal of Physiology 247 R866-R871.
208. Terazono H, Mutoh T, Yamaguchi S, Kobayashi M, Akiyama M, Udo R, Ohdo S, Okamura H & Shibata S 2003 Adrenergic regulation of clock gene expression in mouse liver. PNAS 100 6795-6800.
209. Tharp GD & Folk GE Jr 1965 Rhythmic changes in rate of the mammalian heart and heart cells during prolonged isolation. Comparative Biochemistry and Physiology 14 255-273.
210. Torra IP, Tsibulsky V, Delaunay F, Saladin R, Laudet V, Fruchart JC, Kosykh V & Staels B 2000 Circadian and glucocorticoid regulation of Rev-erbalpha expression in liver. Endocrinology 141 3799-3806.
211. Torres-Farfan C, Seron-Ferre M, Dinet V & Korf HW 2006 Immunocytochemical demonstration of day/night changes of clock gene protein levels in the murine adrenal gland: differences between melatonin-proficient (C3H) and melatonin-deficient (C57BL) mice. Journal of Pineal Research 40 64-70.
212. Ueda HR, Hayashi S, Chen W, Sano M, Machida M, Shigeyoshi Y, Iino M & Hashimoto S 2005 System-level identification of transcriptional circuits underlying mammalian circadian clocks. Nature Genetics 37 187-192.
213. Ueyama T, Krout KE, Nguyen XV, Karpitskiy V, Kollert A, Mettenleiter TC & Loewy AD 1999 Suprachiasmatic nucleus: a central autonomic clock. Nature Neuroscience 2 1051-1053.
214. Ulrich-Lai YM & Engeland WC 2000 Rat adrenal transplants are reinnervated: an invalid model of denervated adrenal cortical tissue. Journal of Neuroendocrinology 12 881-893.
215. Ulrich-Lai YM, Arnhold MM & Engeland WC 2006 Adrenal splanchnic innervation contributes to the diurnal rhythm of plasma corticosterone in rats by modulating adrenal sensitivity to ACTH. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 290 R1128-R1135.
216. Vallone D, Lahiri K, Dickmeis T & Foulkes NS 2007 Start the clock! Circadian rhythms and development. Developmental Dynamics 236 142-155.
217. Veldhuis JD, Iranmanesh A, Johnson ML & Lizarralde G 1990 Amplitude, but not frequency, modulation of adrenocorticotropin secretory bursts gives rise to the nyctohemeral rhythm of the corticotropic axis in man. Journal of Clinical Endocrinology and Metabolism 71 452-463.
218. Vrang N, Larsen PJ & Mikkelsen JD 1995 Direct projection from the suprachiasmatic nucleus to hypophysiotrophic corticotropin-releasing factor immunoreactive cells in the paraventricular nucleus of the hypothalamus demonstrated by means of Phaseolus vulgaris - leucoagglutinin tract tracing. Brain Research 684 61-69.
219. Vujovic N, Davidson AJ & Menaker M 2008 Sympathetic input modulates, but does not determine, phase of peripheral circadian oscillators. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 295 R355-R360.
220. Watts AG, Swanson LW & Sanchez-Watts G 1987 Efferent projections of the suprachiasmatic nucleus: I. Studies using anterograde transport of Phaseolus vulgaris leucoagglutinin in the rat. Journal of Comparative Neurology 258 204-229.
221. Watts AG, Tanimura S & Sanchez-Watts G 2004 Corticotropin-releasing hormone and arginine vasopressin gene transcription in the hypothalamic paraventricular nucleus of unstressed rats: daily rhythms and their interactions with corticosterone. Endocrinology 145 529-540.
222. Weitzman ED, Fukushima D, Nogeire C, Roffwarg H, Gallagher TF & Hellman L 1971 Twenty-four hour pattern of the episodic secretion of cortisol in normal subjects. Journal of Clinical Endocrinology and Metabolism 33 14-22.
223. Welsh DK, Logothetis DE, Meister M & Reppert SM 1995 Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 14 697-706.
224. Welsh DK, Yoo SH, Liu AC, Takahashi JS & Kay SA 2004 Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression. Current Biology 14 2289-2295.
225. Whitmore D, Foulkes NS, Strahle U & Sassone-Corsi P 1998 Zebrafish Clock rhythmic expression reveals independent peripheral circadian oscillators. Nature Neuroscience 1 701-707.
226. Whitmore D, Foulkes NS & Sassone-Corsi P 2000 Light acts directly on organs and cells in culture to set the vertebrate circadian clock. Nature 404 87-91.
227. Whitnall MH, Mezey E & Gainer H 1985 Co-localization of corticotropin-releasing factor and vasopressin in median eminence neurosecretory vesicles. Nature 317 248-250.
228. Windle RJ, Wood SA, Lightman SL & Ingram CD 1998a The pulsatile characteristics of hypothalamo-pituitary-adrenal activity in female Lewis and Fischer 344 rats and its relationship to differential stress responses. Endocrinology 139 4044-4052.
229. Windle RJ, Wood SA, Shanks N, Lightman SL & Ingram CD 1998b Ultradian rhythm of basal corticosterone release in the female rat: dynamic interaction with the response to acute stress. Endocrinology 139 443-450.
230. Windle RJ, Wood SA, Kershaw YM, Lightman SL, Ingram CD & Harbuz MS 2001 Increased corticosterone pulse frequency during adjuvant-induced arthritis and its relationship to alterations in stress responsiveness. Journal of Neuroendocrinology 13 905-911.
231. Wuarin J, Falvey E, Lavery D, Talbot D, Schmidt E, Ossipow V, Fonjallaz P & Schibler U 1992 The role of the transcriptional activator protein DBP in circadian liver gene expression. Journal of Cell Science 16 123-127.
232. Yamamoto T, Nakahata Y, Tanaka M, Yoshida M, Soma H, Shinohara K, Yasuda A, Mamine T & Takumi T 2005 Acute physical stress elevates mouse period1 mRNA expression in mouse peripheral tissues via a glucocorticoid-responsive element. Journal of Biological Chemistry 280 42036-42043.
233. Yamazaki S, Kerbeshian MC, Hocker CG, Block GD & Menaker M 1998 Rhythmic properties of the hamster suprachiasmatic nucleus in vivo. Journal of Neuroscience 18 10709-10723.
234. Yamazaki S, Numano R, Abe M, Hida A, Takahashi R-I, Ueda M, Block GD, Sakaki Y, Menaker M & Tei H 2000 Resetting central and peripheral circadian oscillators in transgenic rats. Science 288 682-685.
235. Yang X, Downes M, Yu RT, Bookout AL, He W, Straume M, Mangelsdorf DJ & Evans RM 2006 Nuclear receptor expression links the circadian clock to metabolism. Cell 126 801-810.
236. Yoo SH, Yamazaki S, Lowrey PL, Shimomura K, Ko CH, Buhr ED, Siepka SM, Hong H-K, Oh WJ, Yoo OJ et al. 2004 PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. PNAS 101 5339-5346.
237. Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK et al. 2001 Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413 131-138.
238. Zheng X & Sehgal A 2008 Probing the relative importance of molecular oscillations in the circadian clock. Genetics 178 1147-1155.