Flavonoids protect pancreatic beta-cells from cytokines mediated apoptosis through the activation of PI3-kinase pathway

Cytokine

Volumn 59, Issue 1, 2012, Pages 65-71

  Lin, Chia Yu ^a   Ni, Chih Chin ^a   Yin, Mei Chin ^b   Lii, Chong Kuei ^b  

^a ASIA UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cell; Apoptosis; Cytokine; IFN ; IL 1 ; INOS; MMP; Naringenin; Quercetin; TNF

Indexed keywords

GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 1BETA; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYRICETIN; NARINGENIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN KINASE B; QUERCETIN; RESVERATROL; SIRTUIN 1; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG MECHANISM; ENZYME ACTIVATION; INSULIN RELEASE; MITOCHONDRIAL MEMBRANE POTENTIAL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CELL LINE; CYCLOOXYGENASE 2; CYTOKINES; CYTOPROTECTION; DENSITOMETRY; ENZYME ACTIVATION; FLAVANONES; FLAVONOIDS; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOLS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; QUERCETIN; RATS; SIGNAL TRANSDUCTION; SIRTUIN 1; SUPEROXIDE DISMUTASE;

EID: 84861682975     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.04.011     Document Type: Article

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