Benefits of complete polyamine deprivation in hormone responsive and hormone resistant MCF-7 human breast adenocarcihoma in vivo

Anticancer Research

Volumn 20, Issue 1 A, 2000, Pages 97-101

  Leveque, Jean ^a,b   Foucher, Fabrice ^a,b   Havouis, Rene ^b   Desury, Dominique ^b   Grall, Jean Yves ^a   Moulinoux, Jacques Philippe ^b  

^a Dept Gynecol Obstet Biol R ^*  (France)

^b Faculté de Médecine   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EFLORNITHINE; ESTRADIOL; ORNITHINE DECARBOXYLASE; POLYAMINE; PUTRESCINE; SPERMIDINE; SPERMINE; TAMOXIFEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CONTROLLED STUDY; CYTOSTASIS; DRUG RESISTANCE; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE SENSITIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; BODY WEIGHT; BREAST NEOPLASMS; DRUG RESISTANCE, NEOPLASM; EFLORNITHINE; ENZYME INHIBITORS; ESTROGEN RECEPTOR MODULATORS; ESTROGENS; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; NEOPLASMS, HORMONE-DEPENDENT; ORNITHINE DECARBOXYLASE; POLYAMINES; PUTRESCINE; RECEPTORS, ESTROGEN; SPERMIDINE; TAMOXIFEN; TUMOR CELLS, CULTURED;

EID: 0034113012     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Pegg AE: Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy. Cancer Res 48: 759-774, 1988.
2. Jänne J, Poso H and Raina A: Polyamines in rapid growth and cancer. Biochim Biophys Acta 473: 241-243, 1978.
3. Lima G, and Shiu RPC: Rôle of polyamines in estradiol-induced growth of human breast cancer cells. Cancer Res 45: 2466-2470, 1985.
4. Kendra KL, and Katzenellenbogen BS: An evaluation of the involvement of polyamines in modulating MCF-7 human breast cancer cell proliferation and progesterone receptor levels by estrogen and antiestrogen. J Steroid Biochem 28: 123-128, 1987.
5. Thomas T, and Thomas T: Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells : therapeutic implications. Breast Cancer Res Tr 29: 189-201, 1993.
6. Glikman P, Manni A, Demers L, and Bartholomew M: Polyamine involvement in the growth of hormone-responsive and -resistant human breast cancer cells in culture. Cancer Res 49: 1371-1376, 1989.
7. Thomas T, Kiang D, Jänne O and Thomas T: Variations in amplification and expression of the ornithine decarboxylase gene in human breast cancer cells. Breast Cancer Res Tr 19: 257-267, 1991.
8. Seiler N, Sarhan S, Graufel C, Jones R, Knodgen B and Moulinoux JP: Endogenous and exogenous polyamines in support to tumor growth. Cancer Res 50: 5077-5083, 1990.
9. Levêque J, Burtin F, Catros-Quemener V, Havouis R, and Moulinoux J-P: The gastrointestinal polyamine source depletion enhances DFMO induced polyamine depletion in MCF-7 human breast cancer cells in vivo. Anticancer Res 18: 2663-2668, 1998.
10. Gottardis MM and Jordan VC: Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long term antiestrogen administration. Cancer Res 48: 5183-5187, 1988.
11. Van de Velde P, Nique F, Brémaud J, Hameau M-C, Philibert D, and Teutsch G: Exploration of the therapeutic potential of the antiestrogen RU 58668 in breast cancer treatment: Ann NY Acad Sc 761: 164-175, 1995.
12. Moulinoux JP, Quemener V, Larzul JJ, Roch AM, and Quash GA: Red blood cell polyamine in mice bearing the Lewis lung carcinoma (3 LL) and in patients with bronchopulmonary cancers: Int J Cancer 34: 277-281, 1984.
13. Seiler N: Separation of ion pair of polyamines and related compounds on reversed phases. In: Clinical liquid chromatography: analysis of endogenous compounds (Kabra PM and Marton LJ, eds). London, CRC Press, 1993, pp 179-187.
14. Verma A and Boutwell RK: Inhibition of carcinogenesis by inhibitors of putrescine biosynthesis. In: Inhihition of polyamine metabolism: biological significance and basis for new therapies (McCann PP, Pegg AE, and Sjoerdsma A, eds). Orlando, Academic Press, 1987, pp 249-258.
15. Bartholeyns J: Treatment of metastatic Lewis lung carcinoma with DL-a-difluoromethylornithine. Eur J Cancer Clin Oncol 19: 567-572, 1981.
16. Bartholeyns J and Koch-Weser J: Effects of a-difluoromethylornithine alone and combined with adriamycin or vindesine on L1210 leukemia in mice, EMT6 solid tumors in mice and solid tumors by injection of hepatoma tisue culture cells in rats. Cancer Res 41: 5158-5161, 1983.
17. Manni A: The role of polyamines in the hormonal control of breast cancer cell proliferation. In: Mammary tumorigenesis and malignant progression (Dickson R and Lippman M, eds) New York. Kluwer Academic Publishers, 1994, pp 209-225.
18. Sarhan S, Knodgen B, and Seiler N: The gastrointestinal tract as polyamine source of tumor growth. Anticancer Res 9: 215-224, 1989.
19. Bardocz S, Grant G, Brown DS, Ralph A, and Pusztai A: Polyamines in food: implications for growth and health. J Biochem Nutr 4: 66-71, 1993.
20. Moulinoux JP, Darcel F, Quemener V, Havouis R, and Seiler N: Inhibition of the growth of the U-251 human glioblastoma in nude mice by polyamine deprivation. Anticancer Res 11: 175-180, 1991.
21. Quemener V, Moulinoux JP, Havouis R, and Seiler N: Polyamine deprivation enhances antitumoral efficacy of chemotherapy. Anticancer Res 12: 1447-1454, 1992.
22. Chamaillard L, Catros-Quemener V, Delcros JG, Bansard JY, Havouis R, Desury D, Commereuc A, Genetet N, and Moulinoux JP:Polyamine deprivation prevents the developmment of tumourinduced immune suppression. Br J Cancer 76: 365-370, 1997.
23. Kremmer T, Palyi I, Daubner D, Boldizsar M, Vincze B, Paulik E, Sugar J, Pokorny E and Tury E: Comparative studies on the polyamine metabolism and DFMO treatment of MCF-7 and MDA-MB-231 breast cancer cell lines and xenografts. Anticancer Res 11: 1807-1814, 1991.
24. Manni A, Badger B, Martel J and Demers L: Role of polyamines on the growth of hormone-responsive and -resistant in human breast cancer cells in nude mice. Cancer Lett 66: 1-9, 1992.
25. Johnston SRD: Acquired tamoxifen resistance in human breast cancer-potential mechanisms and clinical implications. Anti-Cancer Drugs 8: 911-930, 1997.
26. Howell A, Dodwell DJ, Anderson H and Radford J. Response after withdrawal of tamoxifen and progestins in advanced breast cancer. Ann Oncol 3: 611-617, 1992.
27. Manni A, Grove R, Kunzelman S, and Aldaz M: Involvement of the polyamine pathway in breast cancer progression. Cancer Lett 92: 49-57, 1995.