-
1
-
-
0346734280
-
11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer
-
11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer. Clin Cancer Res 2003;9:5922-8.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5922-5928
-
-
Wolff, A.C.1
Armstrong, D.K.2
Fetting, J.H.3
Carducci, M.K.4
Riley, C.D.5
Bender, J.F.6
Casero Jr., R.A.7
Davidson, N.E.8
-
2
-
-
0035094510
-
11-diethylnorspermine (DENSPM) administered TID for 6 days in patients with advanced malignancies
-
11-diethylnorspermine (DENSPM) administered TID for 6 days in patients with advanced malignancies. Invest New Drugs 2001;19:29-39.
-
(2001)
Invest New Drugs
, vol.19
, pp. 29-39
-
-
Streiff, R.R.1
Bender, J.F.2
-
4
-
-
0030659113
-
11-diethylnorspermine in patients with advanced malignancy
-
11-diethylnorspermine in patients with advanced malignancy. Invest New Drugs 1997;15:227-34.
-
(1997)
Invest New Drugs
, vol.15
, pp. 227-234
-
-
Creaven, P.J.1
Perez, R.2
Pendyala, L.3
Meropol, N.J.4
Loewen, G.5
Levine, E.6
Berghorn, E.7
Raghavan, D.8
-
5
-
-
0025833516
-
1-acetyltransferase activity, polyamine pool depletion, and growth inhibition in human melanoma cell lines
-
1- acetyltransferase activity, polyamine pool depletion, and growth inhibition in human melanoma cell lines. Cancer Res 1991;51:3715-20.
-
(1991)
Cancer Res
, vol.51
, pp. 3715-3720
-
-
Porter, C.W.1
Ganis, B.2
Libby, P.R.3
Bergeron, R.J.4
-
6
-
-
0031456453
-
Effects of novel spermine analogues on cell cycle progression and apoptosis in MALME-3M human melanoma cells
-
Kramer DL, Fogel-Petrovic M, Diegelman P, Cooley JM, Bernacki RJ, McManis JS, Bergeron RJ, Porter CW. Effects of novel spermine analogues on cell cycle progression and apoptosis in MALME-3M human melanoma cells. Cancer Res 1997;57:5521-7.
-
(1997)
Cancer Res
, vol.57
, pp. 5521-5527
-
-
Kramer, D.L.1
Fogel-Petrovic, M.2
Diegelman, P.3
Cooley, J.M.4
Bernacki, R.J.5
McManis, J.S.6
Bergeron, R.J.7
Porter, C.W.8
-
7
-
-
0031913230
-
Effects of polyamine analogues on prostatic adenocarcinoma cells in vitro and in vivo
-
Zagaja GP, Shrivastav M, Fleig MJ, Marton LJ, Rinker-Schaeffer CW, Dolan ME. Effects of polyamine analogues on prostatic adenocarcinoma cells in vitro and in vivo. Cancer Chemother Pharmacol 1998;41:505-12.
-
(1998)
Cancer Chemother Pharmacol
, vol.41
, pp. 505-512
-
-
Zagaja, G.P.1
Shrivastav, M.2
Fleig, M.J.3
Marton, L.J.4
Rinker-Schaeffer, C.W.5
Dolan, M.E.6
-
8
-
-
0035418231
-
Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells
-
Chen Y, Kramer DL, Diegelman P, Vujcic S, Porter CW. Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells. Cancer Res 2001;61:6437-44.
-
(2001)
Cancer Res
, vol.61
, pp. 6437-6444
-
-
Chen, Y.1
Kramer, D.L.2
Diegelman, P.3
Vujcic, S.4
Porter, C.W.5
-
9
-
-
0027338998
-
11-bis(ethyl)norspermine against human melanoma xenografts and possible biochemical correlates of drug action
-
11-bis(ethyl)norspermine against human melanoma xenografts and possible biochemical correlates of drug action. Cancer Res 1993; 53:581-6.
-
(1993)
Cancer Res
, vol.53
, pp. 581-586
-
-
Porter, C.W.1
Bernacki, R.J.2
Miller, J.3
Bergeron, R.J.4
-
10
-
-
0032820024
-
Polyamine synthesis and transport inhibition in a human anaplastic thyroid carcinoma cell line in vitro and as xenograft tumors
-
Yatin M, Venkataraman GM, Marcinek R, Ain KB. Polyamine synthesis and transport inhibition in a human anaplastic thyroid carcinoma cell line in vitro and as xenograft tumors. Thyroid 1999;9:805-14.
-
(1999)
Thyroid
, vol.9
, pp. 805-814
-
-
Yatin, M.1
Venkataraman, G.M.2
Marcinek, R.3
Ain, K.B.4
-
13
-
-
28844481026
-
A phase 2 trial of diethylnorspermine (DENSPM) in renal cell carcinoma
-
Redman B, Streiff R, Joh N, Israe W, Bender J, Lenehan P, Lian C, Slichenmyer W. A phase 2 trial of diethylnorspermine (DENSPM) in renal cell carcinoma. Am Soc Clin Oncol 1999, Abstract 1354.
-
(1999)
Am Soc Clin Oncol
, pp. 1354
-
-
Redman, B.1
Streiff, R.2
Joh, N.3
Israe, W.4
Bender, J.5
Lenehan, P.6
Lian, C.7
Slichenmyer, W.8
-
14
-
-
0026665552
-
12-bis(ethyl)-spermine, on polyamine metabolism and cell growth in human melanoma cell lines and melanocytes
-
12-bis(ethyl)-spermine, on polyamine metabolism and cell growth in human melanoma cell lines and melanocytes. Anticancer Res 1992;12:1083-9.
-
(1992)
Anticancer Res
, vol.12
, pp. 1083-1089
-
-
Shappell, N.W.1
Miller, J.T.2
Bergeron, R.J.3
Porter, C.W.4
-
16
-
-
0030053806
-
1-acetyltransferase (SSAT) gene in human lung carcinoma cells
-
1-acetyltransferase (SSAT) gene in human lung carcinoma cells. Biochem J 1996;313:691-6.
-
(1996)
Biochem J
, vol.313
, pp. 691-696
-
-
Xiao, L.1
Casero Jr., R.A.2
-
21
-
-
0024459382
-
Inhibition of putrescine uptake by polypyridinium quaternary-salts in B16-melanoma cells treated with difluoromethylomithine
-
Minchin RF, Martin RL, Summers LA, Ilett KF. Inhibition of putrescine uptake by polypyridinium quaternary-salts in B16-melanoma cells treated with difluoromethylomithine. Biochem J 1989;262:391-5.
-
(1989)
Biochem J
, vol.262
, pp. 391-395
-
-
Minchin, R.F.1
Martin, R.L.2
Summers, L.A.3
Ilett, K.F.4
-
25
-
-
0030043922
-
Isolation of a polyamine transport deficient cell line from the human non-small cell lung carcinoma line NCI H157
-
Shao D, Xiao L, Ha HC, Casero RA Jr. Isolation of a polyamine transport deficient cell line from the human non-small cell lung carcinoma line NCI H157. J Cell Physiol 1996;166:43-8.
-
(1996)
J Cell Physiol
, vol.166
, pp. 43-48
-
-
Shao, D.1
Xiao, L.2
Ha, H.C.3
Casero Jr., R.A.4
-
26
-
-
0028828315
-
1- acetyltransferase without cytotoxicity by the growth-supporting polyamine analogue 1,12-dimethylspermine
-
1-acetyltransferase without cytotoxicity by the growth-supporting polyamine analogue 1,12-dimethylspermine. J Cell Physiol 1995;165:71-6.
-
(1995)
J Cell Physiol
, vol.165
, pp. 71-76
-
-
Yang, J.1
Xiao, L.2
Berkey, K.A.3
Tamez, P.A.4
Coward, J.K.5
Casero Jr., R.A.6
-
27
-
-
0026588785
-
α-methyl polyamines: Metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines
-
Lakanen JR, Coward JK, Pegg AE. α-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines. J Med Chem 1992;35:724-34.
-
(1992)
J Med Chem
, vol.35
, pp. 724-734
-
-
Lakanen, J.R.1
Coward, J.K.2
Pegg, A.E.3
-
28
-
-
0037131188
-
A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism
-
Rasanen TL, Alhonen L, Sinervirta R, Keinanen T, Herzig KH, Suppola S, Khomutov AR, Vepsalainen J, Janne J. A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism. J Biol Chem 2002;277:39867-72.
-
(2002)
J Biol Chem
, vol.277
, pp. 39867-39872
-
-
Rasanen, T.L.1
Alhonen, L.2
Sinervirta, R.3
Keinanen, T.4
Herzig, K.H.5
Suppola, S.6
Khomutov, A.R.7
Vepsalainen, J.8
Janne, J.9
-
29
-
-
20044390384
-
Metabolic stability of α-methylated polyamine derivatives and their use as substitutes for the natural polyamines
-
Jarvinen A, Grigorenko N, Khomutov AR, Hyvonen MT, Uimari A, Vepsalainen J, Sinervirta R, Keinanen TA, Vujcic S, Alhonen L, Porter CW, Janne J. Metabolic stability of α-methylated polyamine derivatives and their use as substitutes for the natural polyamines. J Biol Chem 2005;280:6595-601.
-
(2005)
J Biol Chem
, vol.280
, pp. 6595-6601
-
-
Jarvinen, A.1
Grigorenko, N.2
Khomutov, A.R.3
Hyvonen, M.T.4
Uimari, A.5
Vepsalainen, J.6
Sinervirta, R.7
Keinanen, T.A.8
Vujcic, S.9
Alhonen, L.10
Porter, C.W.11
Janne, J.12
-
30
-
-
0034177792
-
Properties of a polyamine transporter regulated by antizyme
-
Sakata K, Kashiwagi K, Igarashi K. Properties of a polyamine transporter regulated by antizyme. Biochem J 2000;347:297-303.
-
(2000)
Biochem J
, vol.347
, pp. 297-303
-
-
Sakata, K.1
Kashiwagi, K.2
Igarashi, K.3
-
31
-
-
13544265296
-
1- acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells
-
1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells. J Biol Chem 2005;280: 3295-304.
-
(2005)
J Biol Chem
, vol.280
, pp. 3295-3304
-
-
Choi, W.1
Gerner, E.W.2
Ramdas, L.3
Dupart, J.4
Carew, J.5
Proctor, L.6
Huang, P.7
Zhang, W.8
Hamilton, S.R.9
-
32
-
-
4444295545
-
1- acetyltransferase
-
1-acetyltransferase. Mol Cancer Ther 2004;3:813-22, http:\mct.aacr-journals.orgcgicontentabstract37813.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 813-822
-
-
Hector, S.1
Porter, C.W.2
Kramer, D.L.3
Clark, K.4
Prey, J.5
Kisiel, N.6
Diegelman, P.7
Chen, Y.8
Pendyala, L.9
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