SCOPUS 정보 검색 플랫폼

Volumn 7, Issue 6, 2012, Pages 1009-1019

Pentacycloundecane-diol-Based HIV-1 Protease Inhibitors: Biological Screening, 2DNMR, and Molecular Simulation Studies

(10) Honarparvar, Bahareh a Makatini, Maya M a Pawar, Sachin A a Petzold, Katja a Soliman, Mahmoud E S a,b Arvidsson, Per I a,c,d Sayed, Yasien e Govender, Thavendran a Maguire, Glenn E M a Kruger, Hendrik G a

a UNIVERSITY OF KWAZULU NATAL (South Africa)

b Zagazig University (Egypt)

c UPPSALA UNIVERSITY (Sweden)

d ASTRAZENECA R AND D (Sweden)

e UNIVERSITY OF THE WITWATERSRAND (South Africa)

Author keywords

HIV 1 protease; Inhibitors; Molecular docking; Peptides; Transition state analogues

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR; LOPINAVIR; PENTACYCLOUNDECANE; RITONAVIR; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CATALYST; CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVE SITE; HUMAN; HUMAN CELL; HYDROGEN BOND; IC 50; MOLECULAR DOCKING; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; WILD TYPE;

ALKANES; BINDING SITES; DRUG DESIGN; ENZYME ACTIVATION; HIV PROTEASE; HIV-1; HUMANS; MOLECULAR DYNAMICS SIMULATION; PEPTIDES; PROTEASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY;

EID: 84861562373 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201100512 Document Type: Article

Times cited : (20)

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