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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 8, 2011, Pages 2274-2277

Pentacycloundecane-based inhibitors of wild-type C-South African HIV-protease

(11) Makatini, Maya M a Petzold, Katja a Sriharsha, Shimoga N a Soliman, Mahmoud E S b Honarparvar, Bahareh a Arvidsson, Per I a,c,d Sayed, Yasien e Govender, Patrick a Maguire, Glenn E M a Kruger, Hendrik G a Govender, Thavendran a

a UNIVERSITY OF KWAZULU NATAL (South Africa)

b Zagazig University (Egypt)

c UPPSALA UNIVERSITY (Sweden)

d ASTRAZENECA R AND D (Sweden)

e UNIVERSITY OF THE WITWATERSRAND (South Africa)

Author keywords

EASY ROESY; HIV protease inhibitor; Inhibitory concentration (IC50); Molecular docking; Pentacycloundecane peptides

Indexed keywords

ATAZANAVIR; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR; LOPINAVIR; PENTACYCLOUNDECANE ALANYLISOLEUCYLSERINE; PENTACYCLOUNDECANE GLUTAMINYLALANYLISOLEUCYLSERINE; PENTACYCLOUNDECANE GLUTAMYLALANYLISOLEUCINE; PENTACYCLOUNDECANE GLUTAMYLALANYLISOPROPYLSERINE; PENTACYCLOUNDECANE GLUTAMYLVALYLISOLEUCYLSERINE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DRUG CONFORMATION; ENZYME INHIBITION; IC 50; NUCLEAR MAGNETIC RESONANCE;

ALKANES; BINDING SITES; CATALYTIC DOMAIN; COMPUTER SIMULATION; GENOTYPE; HIV; HIV PROTEASE; HIV PROTEASE INHIBITORS; HUMANS; SOUTH AFRICA;

EID: 79953271039 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2011.02.105 Document Type: Article

Times cited : (35)

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