메뉴 건너뛰기




Volumn 9, Issue 1, 2012, Pages 9-23

PI3-K/Akt/JNK/NF-κB is essential for MMP-9 expression and outgrowth in human limbal epithelial cells on intact amniotic membrane

Author keywords

ECM; ERK1 2; JNKs; LSCD; MMP 9; PI3 K; SCs

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE INHIBITOR; SH 5; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 84861548261     PISSN: 18735061     EISSN: 18767753     Source Type: Journal    
DOI: 10.1016/j.scr.2012.02.005     Document Type: Article
Times cited : (71)

References (51)
  • 1
    • 0022470546 scopus 로고
    • Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells
    • Schermer A., Galvin S., Sun T.T. Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J. Cell Biol. 1986, 103:49-62.
    • (1986) J. Cell Biol. , vol.103 , pp. 49-62
    • Schermer, A.1    Galvin, S.2    Sun, T.T.3
  • 2
    • 0029859642 scopus 로고    scopus 로고
    • The evolution of epithelial transplantation for severe ocular surface disease and a proposed classification system
    • Holland E.J., Schwartz G.S. The evolution of epithelial transplantation for severe ocular surface disease and a proposed classification system. Cornea 1996, 15:549-556.
    • (1996) Cornea , vol.15 , pp. 549-556
    • Holland, E.J.1    Schwartz, G.S.2
  • 4
    • 0024523084 scopus 로고
    • Limbal autograft transplantation for ocular surface disorders
    • Kenyon K.R., Tseng S.C. Limbal autograft transplantation for ocular surface disorders. Ophthalmology 1989, 96:709-722.
    • (1989) Ophthalmology , vol.96 , pp. 709-722
    • Kenyon, K.R.1    Tseng, S.C.2
  • 5
    • 0034644186 scopus 로고    scopus 로고
    • Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells
    • Tsai R.J., Li L.M., Chen J.K. Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells. N. Engl. J. Med. 2000, 343:86-93.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 86-93
    • Tsai, R.J.1    Li, L.M.2    Chen, J.K.3
  • 6
    • 0842288676 scopus 로고    scopus 로고
    • Corneal epithelial stem cells at the limbus: looking at some old problems from a new angle
    • Lavker R.M., Tseng S.C., Sun T.T. Corneal epithelial stem cells at the limbus: looking at some old problems from a new angle. Exp. Eye Res. 2004, 78:433-446.
    • (2004) Exp. Eye Res. , vol.78 , pp. 433-446
    • Lavker, R.M.1    Tseng, S.C.2    Sun, T.T.3
  • 7
    • 16244387361 scopus 로고    scopus 로고
    • Role of matrix metalloproteinase-9 in ex vivo expansion of human limbal epithelial cells cultured on human amniotic membrane
    • Sun C.C., Cheng C.Y., Chien C.S., Pang J.H., Ku W.C., Chen P.Y., Yang C.M. Role of matrix metalloproteinase-9 in ex vivo expansion of human limbal epithelial cells cultured on human amniotic membrane. Invest. Ophthalmol. Vis. Sci. 2005, 46:808-815.
    • (2005) Invest. Ophthalmol. Vis. Sci. , vol.46 , pp. 808-815
    • Sun, C.C.1    Cheng, C.Y.2    Chien, C.S.3    Pang, J.H.4    Ku, W.C.5    Chen, P.Y.6    Yang, C.M.7
  • 8
    • 0036139637 scopus 로고    scopus 로고
    • Connexin 43 expression and proliferation of human limbal epithelium on intact and denuded amniotic membrane
    • Grueterich M., Espana E., Tseng S.C. Connexin 43 expression and proliferation of human limbal epithelium on intact and denuded amniotic membrane. Invest. Ophthalmol. Vis. Sci. 2002, 43:63-71.
    • (2002) Invest. Ophthalmol. Vis. Sci. , vol.43 , pp. 63-71
    • Grueterich, M.1    Espana, E.2    Tseng, S.C.3
  • 9
    • 3042619132 scopus 로고    scopus 로고
    • Human amniotic membrane, like corneal epithelial basement membrane, manifests the α5 chain of type IV collagen
    • Endo K., Nakamura T., Kawasaki S., Kinoshita S. Human amniotic membrane, like corneal epithelial basement membrane, manifests the α5 chain of type IV collagen. Invest. Ophthalmol. Vis. Sci. 2004, 45:1771-1774.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 1771-1774
    • Endo, K.1    Nakamura, T.2    Kawasaki, S.3    Kinoshita, S.4
  • 10
    • 0035573698 scopus 로고    scopus 로고
    • Laminin-5 is a component of preserved amniotic membrane
    • Kurpakus-Wheater M. Laminin-5 is a component of preserved amniotic membrane. Curr. Eye Res. 2001, 22:353-357.
    • (2001) Curr. Eye Res. , vol.22 , pp. 353-357
    • Kurpakus-Wheater, M.1
  • 11
    • 33745650748 scopus 로고    scopus 로고
    • Basement membrane dissolution and reassembly by limbal corneal epithelial cells expanded on amniotic membrane
    • Li W., He H., Kuo C.L., Gao Y., Kawakita T., Tseng S.C. Basement membrane dissolution and reassembly by limbal corneal epithelial cells expanded on amniotic membrane. Invest. Ophthalmol. Vis. Sci. 2006, 47:2381-2389.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 2381-2389
    • Li, W.1    He, H.2    Kuo, C.L.3    Gao, Y.4    Kawakita, T.5    Tseng, S.C.6
  • 12
    • 70349576369 scopus 로고    scopus 로고
    • Novel laminin 5 γ2-chain fragments potentiating the limbal epithelial cell outgrowth on amniotic membrane
    • Cheng C.Y., Sun C.C., Yu W.H., Hsieh H.L., Ma D.H., Pang J.H., Yang C.M. Novel laminin 5 γ2-chain fragments potentiating the limbal epithelial cell outgrowth on amniotic membrane. Invest. Ophthalmol. Vis. Sci. 2009, 50:4631-4639.
    • (2009) Invest. Ophthalmol. Vis. Sci. , vol.50 , pp. 4631-4639
    • Cheng, C.Y.1    Sun, C.C.2    Yu, W.H.3    Hsieh, H.L.4    Ma, D.H.5    Pang, J.H.6    Yang, C.M.7
  • 13
  • 14
    • 0033848986 scopus 로고    scopus 로고
    • Matrix metalloproteinases: effectors of development and normal physiology
    • Vu T.H., Werb Z. Matrix metalloproteinases: effectors of development and normal physiology. Genes Dev. 2000, 14:2123-2133.
    • (2000) Genes Dev. , vol.14 , pp. 2123-2133
    • Vu, T.H.1    Werb, Z.2
  • 15
    • 0025114330 scopus 로고
    • Expression of collagenolytic/gelatinolytic metalloproteinases by normal cornea
    • Fini M.E., Girard M.T. Expression of collagenolytic/gelatinolytic metalloproteinases by normal cornea. Invest. Ophthalmol. Vis. Sci. 1990, 31:1779-1788.
    • (1990) Invest. Ophthalmol. Vis. Sci. , vol.31 , pp. 1779-1788
    • Fini, M.E.1    Girard, M.T.2
  • 18
    • 21044432369 scopus 로고    scopus 로고
    • MMP-1 activation by serine proteases and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices
    • Saunders W.B., Bayless K.J., Davis G.E. MMP-1 activation by serine proteases and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices. J. Cell Sci. 2005, 118:2325-2340.
    • (2005) J. Cell Sci. , vol.118 , pp. 2325-2340
    • Saunders, W.B.1    Bayless, K.J.2    Davis, G.E.3
  • 20
    • 0027439698 scopus 로고
    • Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells
    • Sato H., Seiki M. Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene 1993, 8:395-405.
    • (1993) Oncogene , vol.8 , pp. 395-405
    • Sato, H.1    Seiki, M.2
  • 21
    • 58849158423 scopus 로고    scopus 로고
    • Vanillin inhibits matrix metalloproteinase-9 expression through down-regulation of nuclear factor-κB signaling pathway in human hepatocellular carcinoma cells
    • Liang J.A., Wu S.L., Lo H.Y., Hsiang C.Y., Ho T.Y. Vanillin inhibits matrix metalloproteinase-9 expression through down-regulation of nuclear factor-κB signaling pathway in human hepatocellular carcinoma cells. Mol. Pharmacol. 2009, 75:151-157.
    • (2009) Mol. Pharmacol. , vol.75 , pp. 151-157
    • Liang, J.A.1    Wu, S.L.2    Lo, H.Y.3    Hsiang, C.Y.4    Ho, T.Y.5
  • 23
    • 47249146845 scopus 로고    scopus 로고
    • Human corneal epithelial equivalents for ocular surface reconstruction in a complete serum-free culture system without unknown factors
    • Yokoo S., Yamagami S., Usui T., Amano S., Araie M. Human corneal epithelial equivalents for ocular surface reconstruction in a complete serum-free culture system without unknown factors. Invest. Ophthalmol. Vis. Sci. 2008, 49:2438-2443.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 2438-2443
    • Yokoo, S.1    Yamagami, S.2    Usui, T.3    Amano, S.4    Araie, M.5
  • 24
    • 33644841408 scopus 로고    scopus 로고
    • Signaling-transduction pathways required for ex vivo expansion of human limbal explants on intact amniotic membrane
    • He H., Cho H.T., Li W., Kawakita T., Jong L., Tseng S.C. Signaling-transduction pathways required for ex vivo expansion of human limbal explants on intact amniotic membrane. Invest. Ophthalmol. Vis. Sci. 2006, 47:151-157.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 151-157
    • He, H.1    Cho, H.T.2    Li, W.3    Kawakita, T.4    Jong, L.5    Tseng, S.C.6
  • 25
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson G.L., Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002, 298:1911-1912.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 26
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: a play in three Akts
    • Datta S.R., Brunet A., Greenberg M.E. Cellular survival: a play in three Akts. Genes Dev. 1999, 13:2905-2927.
    • (1999) Genes Dev. , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 27
    • 0001582482 scopus 로고
    • Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma
    • Staal S.P. Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. Proc. Natl. Acad. Sci. U. S. A. 1987, 84:5034-5037.
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 5034-5037
    • Staal, S.P.1
  • 28
    • 69049085448 scopus 로고    scopus 로고
    • IL-1β promotes A549 cell migration via MAPKs/AP-1- and NF-κB-dependent matrix metalloproteinase-9 expression
    • Lin C.C., Kuo C.T., Cheng C.Y., Wu C.Y., Lee C.W., Hsieh H.L., Lee I.T., Yang C.M. IL-1β promotes A549 cell migration via MAPKs/AP-1- and NF-κB-dependent matrix metalloproteinase-9 expression. Cell. Signal. 2009, 21:1652-1662.
    • (2009) Cell. Signal. , vol.21 , pp. 1652-1662
    • Lin, C.C.1    Kuo, C.T.2    Cheng, C.Y.3    Wu, C.Y.4    Lee, C.W.5    Hsieh, H.L.6    Lee, I.T.7    Yang, C.M.8
  • 29
    • 0035266290 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activity in epidermal growth factor-stimulated matrix metalloproteinase-9 production and cell surface association
    • Ellerbroek S.M., Halbleib J.M., Benavidez M., Warmka J.K., Wattenberg E.V., Stack M.S., Hudson L.G. Phosphatidylinositol 3-kinase activity in epidermal growth factor-stimulated matrix metalloproteinase-9 production and cell surface association. Cancer Res. 2001, 61:1855-1861.
    • (2001) Cancer Res. , vol.61 , pp. 1855-1861
    • Ellerbroek, S.M.1    Halbleib, J.M.2    Benavidez, M.3    Warmka, J.K.4    Wattenberg, E.V.5    Stack, M.S.6    Hudson, L.G.7
  • 30
    • 0030989819 scopus 로고    scopus 로고
    • Amniotic membrane transplantation for persistent epithelial defects with ulceration
    • Lee S.H., Tseng S.C. Amniotic membrane transplantation for persistent epithelial defects with ulceration. Am. J. Ophthalmol. 1997, 123:303-312.
    • (1997) Am. J. Ophthalmol. , vol.123 , pp. 303-312
    • Lee, S.H.1    Tseng, S.C.2
  • 31
    • 0001112989 scopus 로고    scopus 로고
    • The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κB by directly targeting p65
    • Lyss G., Knorre A., Schmidt T.J., Pahl H.L., Merfort I. The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κB by directly targeting p65. J. Biol. Chem. 1998, 273:33508-33516.
    • (1998) J. Biol. Chem. , vol.273 , pp. 33508-33516
    • Lyss, G.1    Knorre, A.2    Schmidt, T.J.3    Pahl, H.L.4    Merfort, I.5
  • 34
    • 0242579547 scopus 로고    scopus 로고
    • Ex vivo expansion of limbal epithelial stem cells: amniotic membrane serving as a stem cell niche
    • Grueterich M., Espana E.M., Tseng S.C. Ex vivo expansion of limbal epithelial stem cells: amniotic membrane serving as a stem cell niche. Surv. Ophthalmol. 2003, 48:631-646.
    • (2003) Surv. Ophthalmol. , vol.48 , pp. 631-646
    • Grueterich, M.1    Espana, E.M.2    Tseng, S.C.3
  • 35
    • 33749171425 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist (IL-1RA) prevents apoptosis in ex vivo expansion of human limbal epithelial cells cultivated on human amniotic membrane
    • Sun C.C., Su Pang J.H., Cheng C.Y., Cheng H.F., Lee Y.S., Ku W.C., Hsiao C.H., Chen J.K., Yang C.M. Interleukin-1 receptor antagonist (IL-1RA) prevents apoptosis in ex vivo expansion of human limbal epithelial cells cultivated on human amniotic membrane. Stem Cells 2006, 24:2130-2139.
    • (2006) Stem Cells , vol.24 , pp. 2130-2139
    • Sun, C.C.1    Su Pang, J.H.2    Cheng, C.Y.3    Cheng, H.F.4    Lee, Y.S.5    Ku, W.C.6    Hsiao, C.H.7    Chen, J.K.8    Yang, C.M.9
  • 36
    • 0034650486 scopus 로고    scopus 로고
    • Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis
    • Yu Q., Stamenkovic I. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis. Genes Dev. 2000, 14:163-176.
    • (2000) Genes Dev. , vol.14 , pp. 163-176
    • Yu, Q.1    Stamenkovic, I.2
  • 39
    • 16244420116 scopus 로고    scopus 로고
    • Doxycycline inhibits TGF-β1-induced MMP-9 via Smad and MAPK pathways in human corneal epithelial cells
    • Kim H.S., Luo L., Pflugfelder S.C., Li D.Q. Doxycycline inhibits TGF-β1-induced MMP-9 via Smad and MAPK pathways in human corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 2005, 46:840-848.
    • (2005) Invest. Ophthalmol. Vis. Sci. , vol.46 , pp. 840-848
    • Kim, H.S.1    Luo, L.2    Pflugfelder, S.C.3    Li, D.Q.4
  • 41
    • 4344718632 scopus 로고    scopus 로고
    • Dexamethasone inhibition of IL-1-induced collagen degradation by corneal fibroblasts in three-dimensional culture
    • Lu Y., Fukuda K., Liu Y., Kumagai N., Nishida T. Dexamethasone inhibition of IL-1-induced collagen degradation by corneal fibroblasts in three-dimensional culture. Invest. Ophthalmol. Vis. Sci. 2004, 45:2998-3004.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 2998-3004
    • Lu, Y.1    Fukuda, K.2    Liu, Y.3    Kumagai, N.4    Nishida, T.5
  • 42
    • 0032497832 scopus 로고    scopus 로고
    • Structure and function of phosphoinositide 3-kinases
    • Wymann M.P., Pirola L. Structure and function of phosphoinositide 3-kinases. Biochim. Biophys. Acta 1998, 1436:127-150.
    • (1998) Biochim. Biophys. Acta , vol.1436 , pp. 127-150
    • Wymann, M.P.1    Pirola, L.2
  • 43
    • 4644230829 scopus 로고    scopus 로고
    • HGF protects corneal epithelial cells from apoptosis by the PI-3K/Akt-1/Bad- but not the ERK1/2-mediated signaling pathway
    • Kakazu A., Chandrasekher G., Bazan H.E. HGF protects corneal epithelial cells from apoptosis by the PI-3K/Akt-1/Bad- but not the ERK1/2-mediated signaling pathway. Invest. Ophthalmol. Vis. Sci. 2004, 45:3485-3492.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 3485-3492
    • Kakazu, A.1    Chandrasekher, G.2    Bazan, H.E.3
  • 44
    • 35649016567 scopus 로고    scopus 로고
    • PI3 K/Akt/mTOR-mediated translational control regulates proliferation and differentiation of lineage-restricted RoSH stem cell lines
    • Que J., Lian Q., El Oakley R.M., Lim B., Lim S.K. PI3 K/Akt/mTOR-mediated translational control regulates proliferation and differentiation of lineage-restricted RoSH stem cell lines. J. Mol. Signal. 2007, 2:9.
    • (2007) J. Mol. Signal. , vol.2 , pp. 9
    • Que, J.1    Lian, Q.2    El Oakley, R.M.3    Lim, B.4    Lim, S.K.5
  • 45
    • 33645414816 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 induces migration and expression of laminin-5 in cultured human corneal epithelial cells
    • Lee H.K., Lee J.H., Kim M., Kariya Y., Miyazaki K., Kim E.K. Insulin-like growth factor-1 induces migration and expression of laminin-5 in cultured human corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 2006, 47:873-882.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 873-882
    • Lee, H.K.1    Lee, J.H.2    Kim, M.3    Kariya, Y.4    Miyazaki, K.5    Kim, E.K.6
  • 47
    • 21744455891 scopus 로고    scopus 로고
    • Targeted deletion of the integrin β4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-κB, causing defects in epidermal growth and migration
    • Nikolopoulos S.N., Blaikie P., Yoshioka T., Guo W., Puri C., Tacchetti C.Giancotti Targeted deletion of the integrin β4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-κB, causing defects in epidermal growth and migration. Mol. Cell. Biol. 2005, 25:6090-6102.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 6090-6102
    • Nikolopoulos, S.N.1    Blaikie, P.2    Yoshioka, T.3    Guo, W.4    Puri, C.5    Tacchetti, C.G.6
  • 48
    • 0032559962 scopus 로고    scopus 로고
    • Epidermal growth factor activation of NF-κB is mediated through IκBα degradation and intracellular free calcium
    • Sun L., Carpenter G. Epidermal growth factor activation of NF-κB is mediated through IκBα degradation and intracellular free calcium. Oncogene 1998, 16:2095-2102.
    • (1998) Oncogene , vol.16 , pp. 2095-2102
    • Sun, L.1    Carpenter, G.2
  • 49
    • 0032588186 scopus 로고    scopus 로고
    • NF-κB controls cell growth and differentiation through transcriptional regulation of cyclin D1
    • Guttridge D.C., Albanese C., Reuther J.Y., Pestell R.G., Baldwin A.S. NF-κB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol. Cell. Biol. 1999, 19:5785-5799.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 5785-5799
    • Guttridge, D.C.1    Albanese, C.2    Reuther, J.Y.3    Pestell, R.G.4    Baldwin, A.S.5
  • 50
    • 0027996353 scopus 로고
    • The rabbit gene for 92-kDa matrix metalloproteinase. Role of AP1 and AP2 in cell type-specific transcription
    • Fini M.E., Bartlett J.D., Matsubara M., Rinehart W.B., Mody M.K., Girard M.T., Rainville M. The rabbit gene for 92-kDa matrix metalloproteinase. Role of AP1 and AP2 in cell type-specific transcription. J. Biol. Chem. 1994, 269:28620-28628.
    • (1994) J. Biol. Chem. , vol.269 , pp. 28620-28628
    • Fini, M.E.1    Bartlett, J.D.2    Matsubara, M.3    Rinehart, W.B.4    Mody, M.K.5    Girard, M.T.6    Rainville, M.7
  • 51
    • 4644333142 scopus 로고    scopus 로고
    • Cross-talk between phosphatidylinositol 3-kinase/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets
    • Aikin R., Maysinger D., Rosenberg L. Cross-talk between phosphatidylinositol 3-kinase/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets. Endocrinology 2004, 145:4522-4531.
    • (2004) Endocrinology , vol.145 , pp. 4522-4531
    • Aikin, R.1    Maysinger, D.2    Rosenberg, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.