Impaired mitochondrial biogenesis contributes to depletion of functional mitochondria in chronic MPP+ toxicity: Dual roles for ERK1/2

Cell Death and Disease

Volumn 3, Issue 5, 2012, Pages

  Zhu, J H ^a   Gusdon, A M ^a   Cimen, H ^b   Van Houten, B ^c   Koc, E ^d   Chu, C T ^a,e  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^d MARSHALL UNIVERSITY   (United States)

^e UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

1 methyl 4 phenyl 1,2,3,6 tetrahydropyridine; autophagy; mitochondrial biogenesis; mitochondrial transcription factor A; mitogen activated protein kinases; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ARTICLE; BIOGENESIS; CELL PROTECTION; CELL REGENERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MITOCHONDRION; MITOPHAGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE;

1-METHYL-4-PHENYLPYRIDINIUM; AUTOPHAGY; CELL LINE, TUMOR; CELL RESPIRATION; HUMANS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 3; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84861544095     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.46     Document Type: Article

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