Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice

Free Radical Biology and Medicine

Volumn 50, Issue 7, 2011, Pages 866-873

  Flynn, James M ^a   Choi, Sung W ^a   Day, Nicholas U ^a   Gerencser, Akos A ^a   Hubbard, Alan ^a   Melov, Simon ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

Bioenergetics; Free radicals; Mitochondria; Oxidative stress; Respiration; Superoxide dismutase 2; Synaptosome

Indexed keywords

4 AMINOPYRIDINE; ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; CITRATE SYNTHASE; GLUTAMIC ACID; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL ENZYME; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOENERGY; BRAIN REGION; CELL RESPIRATION; CONTROLLED STUDY; DEGENERATIVE DISEASE; FRONTAL CORTEX; MITOCHONDRIAL RESPIRATION; MOUSE; NERVE ENDING; NEUROTRANSMITTER RELEASE; NEWBORN DEATH; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXIDATIVE STRESS; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RESPIROMETRY; SYNAPSE; SYNAPTOSOME;

4-AMINOPYRIDINE; ANIMALS; BIOMIMETICS; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; GENE DELETION; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL DISEASES; NEURODEGENERATIVE DISEASES; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRESYNAPTIC TERMINALS; SUPEROXIDE DISMUTASE; SUPEROXIDES; SYNAPTOSOMES; UNCOUPLING AGENTS;

ANIMALIA; MUS;

EID: 79952042120     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.12.030     Document Type: Article

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