Kinase Inhibitor Scaffolds against Neurodegenerative Diseases from a Southern Australian Ascidian, Didemnum sp.

ChemMedChem

Volumn 7, Issue 6, 2012, Pages 983-990

  Plisson, Fabien ^a   Conte, Melissa ^a   Khalil, Zeinab ^a   Huang, Xiao Cong ^a   Piggott, Andrew M ^a   Capon, Robert J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Enzyme inhibitors; Kinases; Natural products; Neurodegenerative diseases; Ningalins

Indexed keywords

ALKALOID DERIVATIVE; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE INHIBITOR; LAMELLARIN A6; LAMELLARIN G; LAMELLARIN Z; NINGALIN B; NINGALIN C; NINGALIN D; NINGALIN E; NINGALIN F; NINGALIN G; UNCLASSIFIED DRUG;

ARTICLE; ASCIDIACEA; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEGENERATIVE DISEASE; DIDEMNUM; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; FRACTIONATION; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

ANIMALS; AUSTRALIA; BINDING SITES; CARBAZOLES; CASEIN KINASE IDELTA; CATECHOLS; CELL LINE, TUMOR; CELL PROLIFERATION; COMPUTER SIMULATION; COUMARINS; CYCLIN-DEPENDENT KINASE 5; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; NEURODEGENERATIVE DISEASES; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; PYRROLES; UROCHORDATA;

EID: 84861541005     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201200169     Document Type: Article

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