-
1
-
-
80455164646
-
Supplemental studies for cardiovascular risk assessment in safety pharmacology: A critical overview
-
Picard S, Goineau S, Guillaume P, et al. Supplemental studies for cardiovascular risk assessment in safety pharmacology: a critical overview. Cardiovasc Toxicol 2011;11:285-307
-
(2011)
Cardiovasc. Toxicol.
, vol.11
, pp. 285-307
-
-
Picard, S.1
Goineau, S.2
Guillaume, P.3
-
2
-
-
34548351274
-
Thinking inside the box: To cope with an increasing disease burden, drug discovery needs biologically relevant and predictive testing systems
-
Sundstrom LE. Thinking inside the box: to cope with an increasing disease burden, drug discovery needs biologically relevant and predictive testing systems. EMBO Rep 2007;8:40-3
-
(2007)
EMBO Rep.
, vol.8
, pp. 40-43
-
-
Sundstrom, L.E.1
-
4
-
-
0011734831
-
Cultivation of tissues in vitro and its technique
-
Carrel A, Burrow MT. Cultivation of tissues in vitro and its technique. J Exp Med 1911;13:387-96
-
(1911)
J. Exp. Med.
, vol.13
, pp. 387-396
-
-
Carrel, A.1
Burrow, M.T.2
-
5
-
-
84979135771
-
Observations on the living developing nerve fiber
-
Harrison R. Observations on the living developing nerve fiber. Anat Rec 1907;1:116-28
-
(1907)
Anat. Rec.
, vol.1
, pp. 116-128
-
-
Harrison, R.1
-
6
-
-
84933927497
-
On the permanent life of tissues outside of the organism
-
Carrel A. On the permanent life of tissues outside of the organism. J Exp Med 1912;15:516-28
-
(1912)
J.Exp.Med.
, vol.15
, pp. 516-528
-
-
Carrel, A.1
-
8
-
-
0037625909
-
QT interval prolongation and cardiac risk assessment for novel drugs
-
Picard S, Lacroix P. QT interval prolongation and cardiac risk assessment for novel drugs. Curr Opin Investig Drugs 2003;4(3):303-8
-
(2003)
Curr. Opin. Investig Drugs
, vol.4
, Issue.3
, pp. 303-308
-
-
Picard, S.1
Lacroix, P.2
-
9
-
-
0005702104
-
Maintenance of resting membrane potentials in slices of mammalian cerebral cortex and other tissues in vitro
-
Li CL, McIlwain H. Maintenance of resting membrane potentials in slices of mammalian cerebral cortex and other tissues in vitro. J Physiol 1957;139(2):178-90
-
(1957)
J. Physiol.
, vol.139
, Issue.2
, pp. 178-190
-
-
Li, C.L.1
McIlwain, H.2
-
10
-
-
0042118412
-
Organotypic slice cultures: A technique has come of age
-
Review
-
Gahwiler BH, Capogna M, Debanne D, et al. Organotypic slice cultures: a technique has come of age. Trends Neurosci 1997;20(10):471-7. Review
-
(1997)
Trends. Neurosci.
, vol.20
, Issue.10
, pp. 471-477
-
-
Gahwiler, B.H.1
Capogna, M.2
Debanne, D.3
-
11
-
-
0025805120
-
A simple method for organotypic cultures of nervous tissue
-
Stoppini L, Buchs PA, Muller D. A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 1991;37(2):173-82
-
(1991)
J. Neurosci. Methods
, vol.37
, Issue.2
, pp. 173-182
-
-
Stoppini, L.1
Buchs, P.A.2
Muller, D.3
-
12
-
-
22044448897
-
Organotypic cultures as tools for functional screening in the CNS
-
Sundstrom L, Morrison B III, Bradley M, et al. Organotypic cultures as tools for functional screening in the CNS. Drug Discov Today 2005;10(14):993-1000
-
(2005)
Drug Discov Today
, vol.10
, Issue.14
, pp. 993-1000
-
-
Sundstrom, L.1
Morrison III, B.2
Bradley, M.3
-
13
-
-
78650012935
-
Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia
-
Ridky TW, Chow JM, Wong DJ, et al. Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia. Nat Med 2010;16(12):1450-5
-
(2010)
Nat. Med.
, vol.16
, Issue.12
, pp. 1450-455
-
-
Ridky, T.W.1
Chow, J.M.2
Wong, D.J.3
-
16
-
-
0242668870
-
Organ printing: Computer aided Jet-based 3D tissue engineering
-
Mironov V, Bolans T, Trusk T, et al. Organ printing: computer aided Jet-based 3D tissue engineering. Trends Biotechnol 2003;4:157-61
-
(2003)
Trends. Biotechnol.
, vol.4
, pp. 157-161
-
-
Mironov, V.1
Bolans, T.2
Trusk, T.3
-
17
-
-
82055185830
-
Scalable robotic biofabrication of tissue spheroids
-
10.1088/1758-5082/3/2/ 025002
-
Mehesz AN, Brown J, Hajdu Z, et al. Scalable robotic biofabrication of tissue spheroids. Biofabrication 2011;3(2): doi:10.1088/1758-5082/3/2/ 025002
-
(2011)
Biofabrication
, vol.3
, Issue.2
-
-
Mehesz, A.N.1
Brown, J.2
Hajdu, Z.3
-
18
-
-
83455236148
-
Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues
-
Drewitz M, Helbling M, Fried N, et al. Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues. Biotechnol J 2011;6(12):1488-96
-
(2011)
Biotechnol. J.
, vol.6
, Issue.12
, pp. 1488-1496
-
-
Drewitz, M.1
Helbling, M.2
Fried, N.3
-
19
-
-
78751560396
-
High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array
-
Tung YC, Hsiao AY, Allen SG, et al. High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array. Analyst 2011;136(3):473-8
-
(2011)
Analyst
, vol.136
, Issue.3
, pp. 473-478
-
-
Tung, Y.C.1
Hsiao, A.Y.2
Allen, S.G.3
-
20
-
-
77958459904
-
An overview of bioreactor design prototyping and process control for reproducible three-dimensional tissue culture
-
Wiley Marx S, Sandig V, editors. ISBN978-3-527- 31488-1, Hoboken, New Jersey
-
Portner R, Giese C. An overview of bioreactor design prototyping and process control for reproducible three-dimensional tissue culture. In: Marx S, Sandig V, editors. Drug Testing In Vitro, Breakthroughs and Trends in Cell Culture Technology. Wiley ISBN978-3-527-31488-1, Hoboken, New Jersey, 2007
-
(2007)
Drug Testing Vitro, Breakthroughs and Trends in Cell Culture Technology.
-
-
Portner, R.1
Giese, C.2
-
21
-
-
58149178486
-
3D cell culture opens new dimensions in cell-based assays
-
Justice BA, Badr NA, Felder RA. 3D cell culture opens new dimensions in cell-based assays. Drug Discov Today 2009;14(1-2):102-7
-
(2009)
Drug Discov Today
, vol.14
, Issue.1-2
, pp. 102-107
-
-
Justice, B.A.1
Badr, N.A.2
Felder, R.A.3
-
22
-
-
73249131798
-
Paper-supported 3D cell culture for tissue-based bioassays
-
Derda R, Laromaine A, Mammoto A, et al. Paper-supported 3D cell culture for tissue-based bioassays. PNAS 2009;106(44):18457-62
-
(2009)
PNAS
, vol.106
, Issue.44
, pp. 18457-8462
-
-
Derda, R.1
Laromaine, A.2
Mammoto, A.3
-
24
-
-
79958019217
-
In vitro CNS tissue analogues formed by self-organisation of reaggregated post-natal brain tissue
-
Bailey J, O'Connor V, Hannah M, et al. In vitro CNS tissue analogues formed by self-organisation of reaggregated post-natal brain tissue. J Neurochem 2011;117(6):1020-32
-
(2011)
J. Neurochem.
, vol.117
, Issue.6
, pp. 1020-1032
-
-
Bailey, J.1
O'Connor, V.2
Hannah, M.3
-
25
-
-
77951919817
-
Perfused multiwell plate for 3D liver tissue engineering
-
Domansky K, Inman W, Serdy J, et al. Perfused multiwell plate for 3D liver tissue engineering. Lab Chip 2010;10(1):51-8
-
(2010)
Lab. Chip.
, vol.10
, Issue.1
, pp. 51-58
-
-
Domansky, K.1
Inman, W.2
Serdy, J.3
-
26
-
-
1642563967
-
The role of bioreactors in tissue engineering
-
Martin I, Wendt D, Heberer M. The role of bioreactors in tissue engineering. Trends Biotechnol 2004;22(2):80-6
-
(2004)
Trends. Biotechnol.
, vol.22
, Issue.2
, pp. 80-86
-
-
Martin, I.1
Wendt, D.2
Heberer, M.3
-
27
-
-
82355193788
-
Novel strategies to engineering biological tissue in vitro
-
Urciuolo F, Imparato G, Guaccio A, et al. Novel strategies to engineering biological tissue in vitro. Methods Mol Biol 2012;811:223-44
-
(2012)
Methods Mol. Biol.
, Issue.811
, pp. 223-244
-
-
Urciuolo, F.1
Imparato, G.2
Guaccio, A.3
-
28
-
-
34648834682
-
The third dimension bridges the gap between cell culture and live tissue
-
Stelzer EH. The third dimension bridges the gap between cell culture and live tissue. Nat Rev Mol Cell Biol 2007;8(10):839-45
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, Issue.10
, pp. 839-845
-
-
Stelzer, E.H.1
-
30
-
-
79952700142
-
Cell patterning technologies for organotypic tissue fabrication
-
Guillotin B, Guillemot F. Cell patterning technologies for organotypic tissue fabrication. Trends Biotechnol 2011;29(4):183-90
-
(2011)
Trends. Biotechnol.
, vol.29
, Issue.4
, pp. 183-190
-
-
Guillotin, B.1
Guillemot, F.2
-
31
-
-
79551649124
-
A three-dimensional in vitro ovarian cancer coculture model using a high-throughput cell patterning platform
-
Xu F, Celli J, Rizvi I, et al. A three-dimensional in vitro ovarian cancer coculture model using a high-throughput cell patterning platform. Biotechnol J 2011;6(2):204-12
-
(2011)
Biotechnol. J.
, vol.6
, Issue.2
, pp. 204-212
-
-
Xu, F.1
Celli, J.2
Rizvi, I.3
-
32
-
-
0036498496
-
Of layers and spheres: The reaggregate approach in tissue engineering
-
Layer PG, Robitzki A, Rothermel A, et al. Of layers and spheres: the reaggregate approach in tissue engineering. Trends Neurosci 2002;25(3):131-4
-
(2002)
Trends. Neurosci.
, vol.25
, Issue.3
, pp. 131-134
-
-
Layer, P.G.1
Robitzki, A.2
Rothermel, A.3
-
34
-
-
0028096999
-
The use of in vitro reconstituted human skin in dermotoxicity testing
-
Roguet R, Regnier M, Cohen C, et al. The use of in vitro reconstituted human skin in dermotoxicity testing. Toxicol In Vitro 1994;8(4):635-9
-
(1994)
Toxicol. In Vitro.
, vol.8
, Issue.4
, pp. 635-639
-
-
Roguet, R.1
Regnier, M.2
Cohen, C.3
-
35
-
-
34347245999
-
Establishment of 3D organotypic cultures using human neonatal epidermal cells
-
Gangatirkar P, Paquet-Fifield S, Li A, et al. Establishment of 3D organotypic cultures using human neonatal epidermal cells. Nat Protoc 2007;2(1):178-86
-
(2007)
Nat. Protoc.
, vol.2
, Issue.1
, pp. 178-186
-
-
Gangatirkar, P.1
Paquet-Fifield, S.2
Li, A.3
-
36
-
-
79751506790
-
Filter-well technology for advanced three-dimensional cell culture: Perspectives for respiratory research
-
Berube K, Pitt A, Hayden P, et al. Filter-well technology for advanced three-dimensional cell culture: perspectives for respiratory research. Altern Lab Anim 2010;38(Suppl 1):49-65
-
(2010)
Altern. Lab. Anim.
, vol.38
, Issue.SUPPL. 1
, pp. 49-65
-
-
Berube, K.1
Pitt, A.2
Hayden, P.3
-
37
-
-
35648983397
-
Electrophysiological recording of re-aggregating brain cell cultures on multi-electrode arrays to detect acute neurotoxic effects
-
van Vliet E, Stoppini L, Balestrino M, et al. Electrophysiological recording of re-aggregating brain cell cultures on multi-electrode arrays to detect acute neurotoxic effects. Neurotoxicology 2007;28(6):1136-46
-
(2007)
Neurotoxicology
, vol.28
, Issue.6
, pp. 1136-1146
-
-
Van Vliet, E.1
Stoppini, L.2
Balestrino, M.3
-
38
-
-
0031938377
-
Trimethyltin (TMT) neurotoxicity in organotypic rat hippocampal slice cultures
-
Noraberg J, Gramsbergen JB, Fonnum F, et al. Trimethyltin (TMT) neurotoxicity in organotypic rat hippocampal slice cultures. Brain Res 1998;783(2):305-15
-
(1998)
Brain Res.
, vol.783
, Issue.2
, pp. 305-315
-
-
Noraberg, J.1
Gramsbergen, J.B.2
Fonnum, F.3
-
39
-
-
12344276497
-
Organotypic brain slice cultures: An efficient and reliable method for neurotoxicological screening and mechanistic studies
-
Noraberg J. Organotypic brain slice cultures: an efficient and reliable method for neurotoxicological screening and mechanistic studies. Altern Lab Anim 2004;32(4):329-37
-
(2004)
Altern. Lab. Anim.
, vol.32
, Issue.4
, pp. 329-337
-
-
Noraberg, J.1
-
40
-
-
80054719480
-
Antitumor compound testing in glioblastoma organotypic brain cultures
-
Biggs T, Foreman J, Sundstrom L, et al. Antitumor compound testing in glioblastoma organotypic brain cultures. J Biomol Screen 2011;16(8):805-17
-
(2011)
J. Biomol. Screen.
, vol.16
, Issue.8
, pp. 805-817
-
-
Biggs, T.1
Foreman, J.2
Sundstrom, L.3
-
41
-
-
33747601666
-
Organotypic cultures represent tumour microenvironment for drug testing
-
Benbrook DM. Organotypic cultures represent tumour microenvironment for drug testing. Drug Discov Today 2006;2:143-8
-
(2006)
Drug Discov Today
, vol.2
, pp. 143-148
-
-
Benbrook, D.M.1
-
42
-
-
34547931078
-
Modeling tissue morphogenesis and cancer in 3D
-
Yamada K, Cukierman E. Modeling tissue morphogenesis and cancer in 3D. Cell 2007;130:601-10
-
(2007)
Cell
, vol.130
, pp. 601-610
-
-
Yamada, K.1
Cukierman, E.2
-
43
-
-
84855425160
-
Interactions between cancer stem cells and their niche govern metastatic colonization
-
Malanchi I, Santamaria-Martinez A, Susanto E, et al. Interactions between cancer stem cells and their niche govern metastatic colonization. Nature 2011;481(7379):85-9
-
(2011)
Nature
, vol.481
, Issue.7379
, pp. 85-9
-
-
Malanchi, I.1
Santamaria-Martinez, A.2
Susanto, E.3
-
44
-
-
84861487018
-
In vitro three-dimensional (3D) models in cancer research: An update
-
Epub ahead of print]
-
Kimlin LC, Casagrande G, Virador VM. In vitro three-dimensional (3D) models in cancer research: an update. Mol Carcinog 2011. [Epub ahead of print]
-
(2011)
Mol. Carcinog.
-
-
Kimlin, L.C.1
Casagrande, G.2
Virador, V.M.3
-
45
-
-
52149124653
-
Prognostic breast cancer signature Identified from 3D culture Model accurately predicts clinical outcome across multiple independent datasets
-
Martin KJ, Patrick DR, Bissell MJ, et al. Prognostic breast cancer signature Identified from 3D culture Model accurately predicts clinical outcome across multiple independent datasets. PLoS ONE 2008;8:e2994
-
(2008)
PLoS ONE
, vol.8
-
-
Martin, K.J.1
Patrick, D.R.2
Bissell, M.J.3
-
46
-
-
77954386599
-
The long-term survival of in vitro engineered nervous tissue derived from the specific neural differentiation of mouse embryonic stem cells
-
Dubois-Dauphin ML, Toni N, Julien SD, et al. The long-term survival of in vitro engineered nervous tissue derived from the specific neural differentiation of mouse embryonic stem cells. Biomaterials 2010;27:7032-42
-
(2010)
Biomaterials
, vol.27
, pp. 7032-7042
-
-
Dubois-Dauphin, M.L.1
Toni, N.2
Julien, S.D.3
-
47
-
-
65249134409
-
Development of human nervous tissue upon differentiation of embryonic stem cells in three-dimensional culture
-
Preynat-Seauve O, Suter DM, Tirefort D, et al. Development of human nervous tissue upon differentiation of embryonic stem cells in three-dimensional culture. Stem Cells 2009;27(3):509-20
-
(2009)
Stem Cells
, vol.27
, Issue.3
, pp. 509-520
-
-
Preynat-Seauve, O.1
Suter, D.M.2
Tirefort, D.3
-
48
-
-
79955464098
-
The use of induced pluripotent stem cells in drug development
-
Inoue H, Yamanaka S. The use of induced pluripotent stem cells in drug development. Clin Pharmacol Ther 2011;89(5):655-61
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, Issue.5
, pp. 655-661
-
-
Inoue, H.1
Yamanaka, S.2
-
49
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
Ebert AD, Yu J, Rose FF Jr, et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2009;457(7227):277-80
-
(2009)
Nature
, vol.457
, Issue.7227
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose Jr., F.F.3
-
50
-
-
79955884485
-
Modelling schizophrenia using human induced pluripotent stem cells
-
Brennand KJ, Simone A, Jou J, et al. Modelling schizophrenia using human induced pluripotent stem cells. Nature 2011;473(7346):221-5
-
(2011)
Nature
, vol.473
, Issue.7346
, pp. 221-225
-
-
Brennand, K.J.1
Simone, A.2
Jou, J.3
-
51
-
-
80053120148
-
Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells
-
Tobe BT, Snyder EY, Nye JS. Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells. Curr Opin Pharmacol 2011;11(5):521-7
-
(2011)
Curr. Opin. Pharmacol.
, vol.11
, Issue.5
, pp. 521-527
-
-
Tobe, B.T.1
Snyder, E.Y.2
Nye, J.S.3
-
52
-
-
79955053031
-
Induced pluripotent stem cell-derived cardiomyocytes as models for genetic cardiovascular disorders
-
Review
-
Josowitz R, Carvajal-Vergara X, Lemischka IR, et al. Induced pluripotent stem cell-derived cardiomyocytes as models for genetic cardiovascular disorders. Curr Opin Cardiol 2011;26(3):223-9. Review
-
(2011)
Curr. Opin. Cardiol.
, vol.26
, Issue.3
, pp. 223-229
-
-
Josowitz, R.1
Carvajal-Vergara, X.2
Lemischka, I.R.3
-
53
-
-
84858040591
-
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
-
10.1242/ dmm.008409
-
Lahti AL, Kujala VJ, Chapman H, et al. Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture. Dis Model Mech 2012; 2:220-30; doi:10.1242/ dmm.008409
-
(2012)
Dis. Model. Mech.
, vol.2
, pp. 220-220
-
-
Lahti, A.L.1
Kujala, V.J.2
Chapman, H.3
-
54
-
-
85047053857
-
Editorial 'Goodbye, flat biology
-
Editorial 'Goodbye, flat biology? Nature 2003;424:861
-
(2003)
Nature
, vol.424
, pp. 861
-
-
-
55
-
-
34648834682
-
The third dimension bridges the gap between cell culture and live tissue
-
Pampaloni F, Reynaud EG, Stelzer EH. The third dimension bridges the gap between cell culture and live tissue. Nat Rev Mol Cell Biol 2007;8(10):839-45
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, Issue.10
, pp. 839-845
-
-
Pampaloni, F.1
Reynaud, E.G.2
Stelzer, E.H.3
-
56
-
-
77953917382
-
How drug development of the 21st century could benefit from human micro-organoid in-vitro technologies
-
Marx S, Sandig V, editors. Wiley ISBN978-3-527-31488-1, Hoboken, New Jersey
-
Marx U. How drug development of the 21st century could benefit from human micro-organoid in-vitro technologies. In: Marx S, Sandig V, editors. Drug Testing In Vitro: Breakthroughs and Trends in Cell Culture Technology, Wiley ISBN978-3-527-31488-1, Hoboken, New Jersey, 2007. p. 271-83
-
(2007)
Drug Testing In Vitro: Breakthroughs and Trends in Cell Culture Technology
, pp. 271-283
-
-
Marx, U.1
|