-
1
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
-
Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131:861-872. (Pubitemid 350138099)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
2
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318:1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
-
3
-
-
49449096588
-
A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types
-
Wernig M, Lengner CJ, Hanna J, et al. A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nat Biotechnol 2008; 26:916-924.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 916-924
-
-
Wernig, M.1
Lengner, C.J.2
Hanna, J.3
-
4
-
-
55849115999
-
Induced pluripotent stem cells generated without viral integration
-
Stadtfeld M, Nagaya M, Utikal J, et al. Induced pluripotent stem cells generated without viral integration. Science 2008; 322:945-949.
-
(2008)
Science
, vol.322
, pp. 945-949
-
-
Stadtfeld, M.1
Nagaya, M.2
Utikal, J.3
-
5
-
-
64749083939
-
PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
-
Woltjen K, Michael IP, Mohseni P, et al. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 2009; 458:766-770.
-
(2009)
Nature
, vol.458
, pp. 766-770
-
-
Woltjen, K.1
Michael, I.P.2
Mohseni, P.3
-
6
-
-
70350536767
-
A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog
-
Ichida JK, Blanchard J, Lam K, et al. A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell 2009; 5:491-503.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 491-503
-
-
Ichida, J.K.1
Blanchard, J.2
Lam, K.3
-
7
-
-
77958536106
-
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
-
Warren L, Manos PD, Ahfeldt T, et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010; 7:18-30.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 18-30
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
-
8
-
-
56549127713
-
Guidelines and techniques for the generation of induced pluripotent stem cells
-
Maherali N, Hochedlinger K. Guidelines and techniques for the generation of induced pluripotent stem cells. Cell Stem Cell 2008; 3:595-605.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 595-605
-
-
Maherali, N.1
Hochedlinger, K.2
-
9
-
-
0034136393
-
Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers
-
Itskovitz-Eldor J, Schuldiner M, Karsenti D, et al. Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Mol Med 2000; 6:88-95.
-
(2000)
Mol Med
, vol.6
, pp. 88-95
-
-
Itskovitz-Eldor, J.1
Schuldiner, M.2
Karsenti, D.3
-
10
-
-
33751002976
-
Cardiac bodies: A novel culture method for enrichment of cardiomyocytes derived from human embryonic stem cells
-
Police XUC, Hassanipour S, Gold MJ. Cardiac bodies: a novel culture method for enrichment of cardiomyocytes derived from human embryonic stem cells. Stem Cells Develop 2006; 15:631-639.
-
(2006)
Stem Cells Develop
, vol.15
, pp. 631-639
-
-
Police, X.U.C.1
Hassanipour, S.2
Gold, M.J.3
-
11
-
-
44349175948
-
+ embryonic-stem-cell-derived population
-
DOI 10.1038/nature06894, PII NATURE06894
-
Yang L, Soonpaa MH, Adler ED, et al. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature 2008; 453:524-528. (Pubitemid 351733312)
-
(2008)
Nature
, vol.453
, Issue.7194
, pp. 524-528
-
-
Yang, L.1
Soonpaa, M.H.2
Adler, E.D.3
Roepke, T.K.4
Kattman, S.J.5
Kennedy, M.6
Henckaerts, E.7
Bonham, K.8
Abbott, G.W.9
Linden, R.M.10
Field, L.J.11
Keller, G.M.12
-
12
-
-
67349141405
-
Natural and synthetic regulators of embryonic stem cell cardiogenesis
-
Willems E, Bushway PJ, Mercola M. Natural and synthetic regulators of embryonic stem cell cardiogenesis. Pediatr Cardiol 2009; 30:635-642.
-
(2009)
Pediatr Cardiol
, vol.30
, pp. 635-642
-
-
Willems, E.1
Bushway, P.J.2
Mercola, M.3
-
13
-
-
34547823031
-
Identification and selection of cardiomyocytes during human embryonic stem cell differentiation
-
DOI 10.1096/fj.05-5711com
-
Huber I, Itzhaki I, Caspi O, et al. Identification and selection of cardiomyocytes during human embryonic stem cell differentiation. FASEB J 2007; 21:2551-2563. (Pubitemid 47230684)
-
(2007)
FASEB Journal
, vol.21
, Issue.10
, pp. 2551-2563
-
-
Huber, I.1
Itzhaki, I.2
Caspi, O.3
Arbel, G.4
Tzukerman, M.5
Gepstein, A.6
Habib, M.7
Yankelson, L.8
Kehat, I.9
Gepstein, L.10
-
14
-
-
65249179464
-
Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes
-
Kita-Matsuo H, Barcova M, Prigozhina N, et al. Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. PLoS One 2009; 4:e5046.
-
(2009)
PLoS One
, vol.4
-
-
Kita-Matsuo, H.1
Barcova, M.2
Prigozhina, N.3
-
15
-
-
70349868345
-
Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells
-
Xu XQ, Soo SY, Sun W, Zweigerdt R. Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells. Stem Cells 2009; 27:2163-2174.
-
(2009)
Stem Cells
, vol.27
, pp. 2163-2174
-
-
Xu, X.Q.1
Soo, S.Y.2
Sun, W.3
Zweigerdt, R.4
-
16
-
-
0345303845
-
Assessment of the ultrastructural and proliferative properties of human embryonic stem cell-derived cardiomyocytes
-
Snir M, Kehat I, Gepstein A, et al. Assessment of the ultrastructural and proliferative properties of human embryonic stem cell-derived cardiomyocytes. Am J Physiol Heart Circ Physiol 2003; 285:H2355-H2363. (Pubitemid 37443051)
-
(2003)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.285
-
-
Snir, M.1
Kehat, I.2
Gepstein, A.3
Coleman, R.4
Itskovitz-Eldor, J.5
Livne, E.6
Gepstein, L.7
-
17
-
-
35748931742
-
Functional and developmental properties of human embryonic stem cells-derived cardiomyocytes
-
DOI 10.1016/j.jelectrocard.2007.05.035, PII S0022073607006516
-
Binah O, Dolnikov K, Sadan O, et al. Functional and developmental properties of human embryonic stem cells-derived cardiomyocytes. J Electrocardiol 2007; 40 (Suppl 6):S192-S196. (Pubitemid 350052075)
-
(2007)
Journal of Electrocardiology
, vol.40
, Issue.6 SUPPL. 1
-
-
Binah, O.1
Dolnikov, K.2
Sadan, O.3
Shilkrut, M.4
Zeevi-Levin, N.5
Amit, M.6
Danon, A.7
Itskovitz-Eldor, J.8
-
18
-
-
78751687308
-
Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells
-
Germanguz I, Sedan O, Zeevi-Levin N, et al. Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells. J Cell Mol Med 2011; 15:38-51.
-
(2011)
J Cell Mol Med
, vol.15
, pp. 38-51
-
-
Germanguz, I.1
Sedan, O.2
Zeevi-Levin, N.3
-
19
-
-
67349123365
-
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes
-
Tanaka T, Tohyama S, Murata M, et al. In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochem Biophys Res Commun 2009; 385:497-502.
-
(2009)
Biochem Biophys Res Commun
, vol.385
, pp. 497-502
-
-
Tanaka, T.1
Tohyama, S.2
Murata, M.3
-
20
-
-
34547651205
-
Prevalence and clinical significance of cardiovascular abnormalities in patients with the LEOPARD syndrome
-
DOI 10.1016/j.amjcard.2007.03.093, PII S000291490700968X
-
Limongelli G, Pacileo G, Marino B, et al. Prevalence and clinical significance of cardiovascular abnormalities in patients with the LEOPARD syndrome. Am J Cardiol 2007; 100:736-741. (Pubitemid 47223154)
-
(2007)
American Journal of Cardiology
, vol.100
, Issue.4
, pp. 736-741
-
-
Limongelli, G.1
Pacileo, G.2
Marino, B.3
Digilio, M.C.4
Sarkozy, A.5
Elliott, P.6
Versacci, P.7
Calabro, P.8
De Zorzi, A.9
Di Salvo, G.10
Syrris, P.11
Patton, M.12
McKenna, W.J.13
Dallapiccola, B.14
Calabro, R.15
-
22
-
-
18344385476
-
Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
-
DOI 10.1038/ng772
-
Tartaglia M, Mehler EL, Goldberg R, et al. Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nat Genet 2001; 29:465-468. (Pubitemid 34326699)
-
(2001)
Nature Genetics
, vol.29
, Issue.4
, pp. 465-468
-
-
Tartaglia, M.1
Mehler, E.L.2
Goldberg, R.3
Zampino, G.4
Brunner, H.G.5
Kremer, H.6
Van Der Burgt, I.7
Crosby, A.H.8
Ion, A.9
Jeffery, S.10
Kalidas, K.11
Patton, M.A.12
Kucherlapati, R.S.13
Gelb, B.D.14
-
23
-
-
0036074033
-
Grouping of multiple-lentigines/LEOPARD and Noonan syndromes on the PTPN11 gene
-
DOI 10.1086/341528
-
Digilio MC, Conti E, Sarkozy A, et al. Grouping of multiple-lentigines/ LEOPARD and Noonan syndromes on the PTPN11 gene. Am J Hum Genet 2002; 71:389-394. (Pubitemid 34800254)
-
(2002)
American Journal of Human Genetics
, vol.71
, Issue.2
, pp. 389-394
-
-
Digilio, M.C.1
Conti, E.2
Sarkozy, A.3
Mingarelli, R.4
Dottorini, T.5
Marino, B.6
Pizzuti, A.7
Dallapiccola, B.8
-
24
-
-
1542619343
-
Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation
-
DOI 10.1002/humu.20005
-
Fragale A, Tartaglia M, Wu J, Gelb BD. Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation. Hum Mutat 2004; 23:267-277. (Pubitemid 38337891)
-
(2004)
Human Mutation
, vol.23
, Issue.3
, pp. 267-277
-
-
Fragale, A.1
Tartaglia, M.2
Wu, J.3
Gelb, B.D.4
-
25
-
-
33646096207
-
PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects
-
DOI 10.1074/jbc.M513068200
-
Kontaridis MI, Swanson KD, David FS, et al. PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects. J Biol Chem 2006; 281:6785-6792. (Pubitemid 43847615)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.10
, pp. 6785-6792
-
-
Kontaridis, M.I.1
Swanson, K.D.2
David, F.S.3
Barford, D.4
Neel, B.G.5
-
26
-
-
57649203360
-
Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development
-
Oishi K, Zhang H, Gault WJ, et al. Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development. Hum Mol Genet 2008; 18:193-201.
-
(2008)
Hum Mol Genet
, vol.18
, pp. 193-201
-
-
Oishi, K.1
Zhang, H.2
Gault, W.J.3
-
27
-
-
77953443251
-
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
-
Carvajal-Vergara X, Sevilla A, D'Souza SL, et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 2010; 465:808-812.
-
(2010)
Nature
, vol.465
, pp. 808-812
-
-
Carvajal-Vergara, X.1
Sevilla, A.2
D'Souza, S.L.3
-
29
-
-
77957729169
-
Patient-specific induced pluripotent stemcell models for long-QT syndrome
-
Moretti A, Bellin M, Welling A, et al. Patient-specific induced pluripotent stemcell models for long-QT syndrome. NEJM 2010; 363:1397-1409
-
(2010)
NEJM
, vol.363
, pp. 1397-1409
-
-
Moretti, A.1
Bellin, M.2
Welling, A.3
-
30
-
-
79952446402
-
Modelling the long QT syndrome with induced pluripotent stem cells
-
Epub ahead of print
-
Itzhaki I, Maizels L, Huber I, et al. Modelling the long QT syndrome with induced pluripotent stem cells. Nature 2011 [Epub ahead of print].
-
(2011)
Nature
-
-
Itzhaki, I.1
Maizels, L.2
Huber, I.3
-
31
-
-
77955321344
-
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
-
Ieda M, Fu JD, Delgado-Olguin P, et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 2010; 142:375-386.
-
(2010)
Cell
, vol.142
, pp. 375-386
-
-
Ieda, M.1
Fu, J.D.2
Delgado-Olguin, P.3
-
32
-
-
79952273710
-
Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy
-
Epub ahead of print
-
Efe JA, Hilcove S, Kim J, et al. Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat Cell Biol 2011 [Epub ahead of print].
-
(2011)
Nat Cell Biol
-
-
Efe, J.A.1
Hilcove, S.2
Kim, J.3
-
33
-
-
67650071028
-
Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages
-
Bu L, Jiang X, Martin-Puig S, et al. Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages. Nature 2009; 460:113-117.
-
(2009)
Nature
, vol.460
, pp. 113-117
-
-
Bu, L.1
Jiang, X.2
Martin-Puig, S.3
-
34
-
-
77952306707
-
Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors
-
Moretti A, Bellin M, Jung CB, et al. Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors. FASEB J 2010; 24:700-711.
-
(2010)
FASEB J
, vol.24
, pp. 700-711
-
-
Moretti, A.1
Bellin, M.2
Jung, C.B.3
-
35
-
-
68249108915
-
The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells
-
Yokoo N, Baba S, Kaichi S, et al. The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells. Biochem Biophys Res Commun 2009; 387:482-488.
-
(2009)
Biochem Biophys Res Commun
, vol.387
, pp. 482-488
-
-
Yokoo, N.1
Baba, S.2
Kaichi, S.3
-
36
-
-
77955937897
-
Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening
-
Dick E, Rajamohan D, Ronksley J, Denning C. Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening. Biochem Soc Trans 2010; 38:1037-1045.
-
(2010)
Biochem Soc Trans
, vol.38
, pp. 1037-1045
-
-
Dick, E.1
Rajamohan, D.2
Ronksley, J.3
Denning, C.4
|