메뉴 건너뛰기




Volumn 26, Issue 3, 2011, Pages 223-229

Induced pluripotent stem cell-derived cardiomyocytes as models for genetic cardiovascular disorders

Author keywords

hypertrophic cardiomyopathy; induced pluripotent stem cells; LEOPARD syndrome; long QT syndrome

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; RAS PROTEIN;

EID: 79955053031     PISSN: 02684705     EISSN: None     Source Type: Journal    
DOI: 10.1097/HCO.0b013e32834598ad     Document Type: Article
Times cited : (29)

References (36)
  • 1
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
    • Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131:861-872. (Pubitemid 350138099)
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 2
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318:1917-1920.
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 3
    • 49449096588 scopus 로고    scopus 로고
    • A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types
    • Wernig M, Lengner CJ, Hanna J, et al. A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nat Biotechnol 2008; 26:916-924.
    • (2008) Nat Biotechnol , vol.26 , pp. 916-924
    • Wernig, M.1    Lengner, C.J.2    Hanna, J.3
  • 4
    • 55849115999 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated without viral integration
    • Stadtfeld M, Nagaya M, Utikal J, et al. Induced pluripotent stem cells generated without viral integration. Science 2008; 322:945-949.
    • (2008) Science , vol.322 , pp. 945-949
    • Stadtfeld, M.1    Nagaya, M.2    Utikal, J.3
  • 5
    • 64749083939 scopus 로고    scopus 로고
    • PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen K, Michael IP, Mohseni P, et al. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 2009; 458:766-770.
    • (2009) Nature , vol.458 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3
  • 6
    • 70350536767 scopus 로고    scopus 로고
    • A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog
    • Ichida JK, Blanchard J, Lam K, et al. A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell 2009; 5:491-503.
    • (2009) Cell Stem Cell , vol.5 , pp. 491-503
    • Ichida, J.K.1    Blanchard, J.2    Lam, K.3
  • 7
    • 77958536106 scopus 로고    scopus 로고
    • Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
    • Warren L, Manos PD, Ahfeldt T, et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010; 7:18-30.
    • (2010) Cell Stem Cell , vol.7 , pp. 18-30
    • Warren, L.1    Manos, P.D.2    Ahfeldt, T.3
  • 8
    • 56549127713 scopus 로고    scopus 로고
    • Guidelines and techniques for the generation of induced pluripotent stem cells
    • Maherali N, Hochedlinger K. Guidelines and techniques for the generation of induced pluripotent stem cells. Cell Stem Cell 2008; 3:595-605.
    • (2008) Cell Stem Cell , vol.3 , pp. 595-605
    • Maherali, N.1    Hochedlinger, K.2
  • 9
    • 0034136393 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers
    • Itskovitz-Eldor J, Schuldiner M, Karsenti D, et al. Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Mol Med 2000; 6:88-95.
    • (2000) Mol Med , vol.6 , pp. 88-95
    • Itskovitz-Eldor, J.1    Schuldiner, M.2    Karsenti, D.3
  • 10
    • 33751002976 scopus 로고    scopus 로고
    • Cardiac bodies: A novel culture method for enrichment of cardiomyocytes derived from human embryonic stem cells
    • Police XUC, Hassanipour S, Gold MJ. Cardiac bodies: a novel culture method for enrichment of cardiomyocytes derived from human embryonic stem cells. Stem Cells Develop 2006; 15:631-639.
    • (2006) Stem Cells Develop , vol.15 , pp. 631-639
    • Police, X.U.C.1    Hassanipour, S.2    Gold, M.J.3
  • 12
    • 67349141405 scopus 로고    scopus 로고
    • Natural and synthetic regulators of embryonic stem cell cardiogenesis
    • Willems E, Bushway PJ, Mercola M. Natural and synthetic regulators of embryonic stem cell cardiogenesis. Pediatr Cardiol 2009; 30:635-642.
    • (2009) Pediatr Cardiol , vol.30 , pp. 635-642
    • Willems, E.1    Bushway, P.J.2    Mercola, M.3
  • 14
    • 65249179464 scopus 로고    scopus 로고
    • Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes
    • Kita-Matsuo H, Barcova M, Prigozhina N, et al. Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. PLoS One 2009; 4:e5046.
    • (2009) PLoS One , vol.4
    • Kita-Matsuo, H.1    Barcova, M.2    Prigozhina, N.3
  • 15
    • 70349868345 scopus 로고    scopus 로고
    • Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells
    • Xu XQ, Soo SY, Sun W, Zweigerdt R. Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells. Stem Cells 2009; 27:2163-2174.
    • (2009) Stem Cells , vol.27 , pp. 2163-2174
    • Xu, X.Q.1    Soo, S.Y.2    Sun, W.3    Zweigerdt, R.4
  • 18
    • 78751687308 scopus 로고    scopus 로고
    • Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells
    • Germanguz I, Sedan O, Zeevi-Levin N, et al. Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells. J Cell Mol Med 2011; 15:38-51.
    • (2011) J Cell Mol Med , vol.15 , pp. 38-51
    • Germanguz, I.1    Sedan, O.2    Zeevi-Levin, N.3
  • 19
    • 67349123365 scopus 로고    scopus 로고
    • In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes
    • Tanaka T, Tohyama S, Murata M, et al. In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochem Biophys Res Commun 2009; 385:497-502.
    • (2009) Biochem Biophys Res Commun , vol.385 , pp. 497-502
    • Tanaka, T.1    Tohyama, S.2    Murata, M.3
  • 24
    • 1542619343 scopus 로고    scopus 로고
    • Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation
    • DOI 10.1002/humu.20005
    • Fragale A, Tartaglia M, Wu J, Gelb BD. Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation. Hum Mutat 2004; 23:267-277. (Pubitemid 38337891)
    • (2004) Human Mutation , vol.23 , Issue.3 , pp. 267-277
    • Fragale, A.1    Tartaglia, M.2    Wu, J.3    Gelb, B.D.4
  • 25
    • 33646096207 scopus 로고    scopus 로고
    • PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects
    • DOI 10.1074/jbc.M513068200
    • Kontaridis MI, Swanson KD, David FS, et al. PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects. J Biol Chem 2006; 281:6785-6792. (Pubitemid 43847615)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.10 , pp. 6785-6792
    • Kontaridis, M.I.1    Swanson, K.D.2    David, F.S.3    Barford, D.4    Neel, B.G.5
  • 26
    • 57649203360 scopus 로고    scopus 로고
    • Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development
    • Oishi K, Zhang H, Gault WJ, et al. Phosphatase-defective LEOPARD syndrome mutations in PTPN11 gene have gain-of-function effects during Drosophila development. Hum Mol Genet 2008; 18:193-201.
    • (2008) Hum Mol Genet , vol.18 , pp. 193-201
    • Oishi, K.1    Zhang, H.2    Gault, W.J.3
  • 27
    • 77953443251 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
    • Carvajal-Vergara X, Sevilla A, D'Souza SL, et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 2010; 465:808-812.
    • (2010) Nature , vol.465 , pp. 808-812
    • Carvajal-Vergara, X.1    Sevilla, A.2    D'Souza, S.L.3
  • 29
    • 77957729169 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stemcell models for long-QT syndrome
    • Moretti A, Bellin M, Welling A, et al. Patient-specific induced pluripotent stemcell models for long-QT syndrome. NEJM 2010; 363:1397-1409
    • (2010) NEJM , vol.363 , pp. 1397-1409
    • Moretti, A.1    Bellin, M.2    Welling, A.3
  • 30
    • 79952446402 scopus 로고    scopus 로고
    • Modelling the long QT syndrome with induced pluripotent stem cells
    • Epub ahead of print
    • Itzhaki I, Maizels L, Huber I, et al. Modelling the long QT syndrome with induced pluripotent stem cells. Nature 2011 [Epub ahead of print].
    • (2011) Nature
    • Itzhaki, I.1    Maizels, L.2    Huber, I.3
  • 31
    • 77955321344 scopus 로고    scopus 로고
    • Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
    • Ieda M, Fu JD, Delgado-Olguin P, et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 2010; 142:375-386.
    • (2010) Cell , vol.142 , pp. 375-386
    • Ieda, M.1    Fu, J.D.2    Delgado-Olguin, P.3
  • 32
    • 79952273710 scopus 로고    scopus 로고
    • Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy
    • Epub ahead of print
    • Efe JA, Hilcove S, Kim J, et al. Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat Cell Biol 2011 [Epub ahead of print].
    • (2011) Nat Cell Biol
    • Efe, J.A.1    Hilcove, S.2    Kim, J.3
  • 33
    • 67650071028 scopus 로고    scopus 로고
    • Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages
    • Bu L, Jiang X, Martin-Puig S, et al. Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages. Nature 2009; 460:113-117.
    • (2009) Nature , vol.460 , pp. 113-117
    • Bu, L.1    Jiang, X.2    Martin-Puig, S.3
  • 34
    • 77952306707 scopus 로고    scopus 로고
    • Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors
    • Moretti A, Bellin M, Jung CB, et al. Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors. FASEB J 2010; 24:700-711.
    • (2010) FASEB J , vol.24 , pp. 700-711
    • Moretti, A.1    Bellin, M.2    Jung, C.B.3
  • 35
    • 68249108915 scopus 로고    scopus 로고
    • The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells
    • Yokoo N, Baba S, Kaichi S, et al. The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells. Biochem Biophys Res Commun 2009; 387:482-488.
    • (2009) Biochem Biophys Res Commun , vol.387 , pp. 482-488
    • Yokoo, N.1    Baba, S.2    Kaichi, S.3
  • 36
    • 77955937897 scopus 로고    scopus 로고
    • Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening
    • Dick E, Rajamohan D, Ronksley J, Denning C. Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening. Biochem Soc Trans 2010; 38:1037-1045.
    • (2010) Biochem Soc Trans , vol.38 , pp. 1037-1045
    • Dick, E.1    Rajamohan, D.2    Ronksley, J.3    Denning, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.