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Volumn 16, Issue 8, 2011, Pages 805-817

Antitumor compound testing in Glioblastoma organotypic brain cultures

Author keywords

3D; Glioblastoma; Organotypic cultures; Temozolomide

Indexed keywords

CYTARABINE; PACLITAXEL; TEMOZOLOMIDE;

EID: 80054719480     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111414895     Document Type: Article
Times cited : (12)

References (41)
  • 1
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen, P. Y.; Kesari, S. Malignant Gliomas in Adults. N. Engl. J. Med. 2008, 359, 492-507.
    • (2008) N. Engl. J. Med. , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 3
    • 70350034197 scopus 로고    scopus 로고
    • Contemporary pre-clinical development of anticancer agents: What are the optimal preclinical models?
    • Damia, G.; D'Incalci, M. Contemporary Pre-Clinical Development of Anticancer Agents: What Are the Optimal Preclinical Models? Eur. J. Cancer. 2009, 45, 2768-2781.
    • (2009) Eur. J. Cancer. , vol.45 , pp. 2768-2781
    • Damia, G.1    D'Incalci, M.2
  • 4
    • 77949957365 scopus 로고    scopus 로고
    • Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents
    • Sharma, S. V.; Haber, D. A.; Settleman, J. Cell Line-Based Platforms to Evaluate the Therapeutic Efficacy of Candidate Anticancer Agents. Nat. Rev. Cancer. 2010, 10, 241-253.
    • (2010) Nat. Rev. Cancer. , vol.10 , pp. 241-253
    • Sharma, S.V.1    Haber, D.A.2    Settleman, J.3
  • 5
    • 23744472983 scopus 로고    scopus 로고
    • Gene expression perturbation in vitro - A growing case for three-dimensional (3D) culture systems
    • DOI 10.1016/j.semcancer.2005.06.009, PII S1044579X05000416
    • Birgersdotter, A.; Sandberg, R.; Ernberg, I. Gene Expression Perturbation In Vitro: A Growing Case for Three-Dimensional (3D) Culture Systems. Semin. Cancer Biol. 2005, 15, 405-412. (Pubitemid 41140308)
    • (2005) Seminars in Cancer Biology , vol.15 , Issue.SPEC. ISS.5 , pp. 405-412
    • Birgersdotter, A.1    Sandberg, R.2    Ernberg, I.3
  • 6
    • 34648834682 scopus 로고    scopus 로고
    • The third dimension bridges the gap between cell culture and live tissue
    • DOI 10.1038/nrm2236, PII NRM2236
    • Pampaloni, F.; Reynaud, E. G.; Stelzer, E. H. The Third Dimension Bridges the Gap between Cell Culture and Live Tissue. Nat. Rev. Mol. Cell. Biol. 2007, S, 839-845. (Pubitemid 47462131)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.10 , pp. 839-845
    • Pampaloni, F.1    Reynaud, E.G.2    Stelzer, E.H.K.3
  • 8
    • 75749146306 scopus 로고    scopus 로고
    • Plasticity of cell migration: A multiscale tuning model
    • Friedl, P.; Wolf, K. Plasticity of Cell Migration: A Multiscale Tuning Model. J. Cell. Biol. 2010, 1 SS, 11-19.
    • (2010) J. Cell. Biol. , vol.1 SS , pp. 11-19
    • Friedl, P.1    Wolf, K.2
  • 9
    • 34547931078 scopus 로고    scopus 로고
    • Modeling Tissue Morphogenesis and Cancer in 3D
    • DOI 10.1016/j.cell.2007.08.006, PII S0092867407010288
    • Yamada, K. M.; Cukierman, E. Modeling Tissue Morphogenesis and Cancer in 3D. Cell. 2007, 130, 601-610. (Pubitemid 47268064)
    • (2007) Cell , vol.130 , Issue.4 , pp. 601-610
    • Yamada, K.M.1    Cukierman, E.2
  • 10
    • 36849009670 scopus 로고    scopus 로고
    • Experimental anti-tumor therapy in 3-D: Spheroids - Old hat or new challenge?
    • DOI 10.1080/09553000701727531, PII 787786632
    • Friedrich, J.; Ebner, R.; Kunz-Schughart, L. A. Experimental Anti-Tumor Therapy in 3-D: Spheroids-Old Hat or New Challenge? Int. J. Radiat. Biol. 2007, S3, 849-871. (Pubitemid 350219104)
    • (2007) International Journal of Radiation Biology , vol.83 , Issue.11-12 , pp. 849-871
    • Friedrich, J.1    Ebner, R.2    Kunz-Schughart, L.A.3
  • 14
    • 33645986455 scopus 로고    scopus 로고
    • Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: A randomised controlled multicentre phase III trial
    • Stummer, W.; Pichlmeier, U.; Meinel, T.; Wiestler, O. D.; Zanella, F.; Reulen, H. J. Fluorescence-Guided Surgery with 5-Aminolevulinic Acid for Resection of Malignant Glioma: A Randomised Controlled Multicentre Phase III Trial. Lancet Oncol. 2006, 7, 392-401.
    • (2006) Lancet Oncol. , vol.7 , pp. 392-401
    • Stummer, W.1    Pichlmeier, U.2    Meinel, T.3    Wiestler, O.D.4    Zanella, F.5    Reulen, H.J.6
  • 16
    • 70449384375 scopus 로고    scopus 로고
    • Generation of an immortalized astrocyte cell line from H-2Kb-tsA58 mice to study the role of astrocytes in brain metastasis
    • Langley, R. R.; Fan, D.; Guo, L.; Zhang, C.; Lin, Q.; Brantley, E. C.; McCarty, J. H.; Fidler, I. J. Generation of an Immortalized Astrocyte Cell Line from H-2Kb-tsA58 Mice to Study the Role of Astrocytes in Brain Metastasis. Int. J. Oncol. 2009, 35, 665-672.
    • (2009) Int. J. Oncol. , vol.35 , pp. 665-672
    • Langley, R.R.1    Fan, D.2    Guo, L.3    Zhang, C.4    Lin, Q.5    Brantley, E.C.6    McCarty, J.H.7    Fidler, I.J.8
  • 17
    • 0028856184 scopus 로고
    • Reactions of astrocytes and microglial cells around hematogenous metastases of the human brain: Expression of endothelin-like immunoreactivity in reactive astrocytes and activation of microglial cells
    • Zhang, M.; Olsson, Y. Reactions of Astrocytes and Microglial Cells around Hematogenous Metastases of the Human Brain: Expression of Endothelin-Like Immunoreactivity in Reactive Astrocytes and Activation of Microglial Cells. J. Neurol. Sci. 1995, 134, 26-32.
    • (1995) J. Neurol. Sci. , vol.134 , pp. 26-32
    • Zhang, M.1    Olsson, Y.2
  • 18
    • 77949266026 scopus 로고    scopus 로고
    • In vivo assessment of high-grade glioma biochemistry using microdialysis: A study of energy-related molecules, growth factors and cytokines
    • Marcus, H. J.; Carpenter, K. L.; Price, S. J.; Hutchinson, P. J. In Vivo Assessment of High-Grade Glioma Biochemistry Using Microdialysis: A Study of Energy-Related Molecules, Growth Factors and Cytokines. J. Neurooncol. 2010, 97, 11-23.
    • (2010) J. Neurooncol. , vol.97 , pp. 11-23
    • Marcus, H.J.1    Carpenter, K.L.2    Price, S.J.3    Hutchinson, P.J.4
  • 19
    • 33744942376 scopus 로고    scopus 로고
    • Acid-mediated tumor invasion: A multidisciplinary study
    • DOI 10.1158/0008-5472.CAN-05-4193
    • Gatenby, R. A.; Gawlinski, E. T.; Gmitro, A. F.; Kaylor, B.; Gillies, R. J. Acid-Mediated Tumor Invasion: A Multidisciplinary Study. Cancer Res. 2006, 66, 5216-5223. (Pubitemid 43844945)
    • (2006) Cancer Research , vol.66 , Issue.10 , pp. 5216-5223
    • Gatenby, R.A.1    Gawlinski, E.T.2    Gmitro, A.F.3    Kaylor, B.4    Gillies, R.J.5
  • 20
    • 0035863059 scopus 로고    scopus 로고
    • A phase II study of paclitaxel in patients with recurrent malignant glioma using different doses depending upon the concomitant use of anticonvulsants: A North American brain tumor consortium report
    • DOI 10.1002/1097-0142(20010115)91:2<417::AID-CNCR1016>3.0.CO;2-9
    • Chang, S. M.; Kuhn, J. G.; Robins, H. I.; Schold, S. C, Jr.; Spence, A. M.; Berger, M. S.; Mehta, M.; Pollack, I. F.; Rankin, C.; Prados, M. D. A Phase II Study of Paclitaxel in Patients with Recurrent Malignant Glioma Using Different Doses Depending upon the Concomitant Use of Anticonvulsants: A North American Brain Tumor Consortium Report. Cancer. 2001, 91, 417-422. (Pubitemid 32099244)
    • (2001) Cancer , vol.91 , Issue.2 , pp. 417-422
    • Chang, S.M.1    Kuhn, J.G.2    Ian Robins, H.3    Clifford Schold, S.4    Spence, A.M.5    Berger, M.S.6    Mehta, M.P.7    Pollack, I.F.8    Rankin, C.9    Prados, M.D.10
  • 21
    • 0021325522 scopus 로고
    • Cisplatin plus cytosine arabinoside in adults with malignant gliomas
    • Stewart, D. J.; Richard, M. T.; Benoit, B.; Hugenholtz, H.; Russell, N.; Dennery, J.; Peterson, E.; Grahovac, Z.; Belanger, G.; Aitkens, S.; et al. Cisplatin Plus Cytosine Arabinoside in Adults with Malignant Gliomas. J Neurooncol. 1984, 2, 29-34. (Pubitemid 14148612)
    • (1984) Journal of Neuro-Oncology , vol.2 , Issue.1 , pp. 29-34
    • Stewart, D.J.1    Richard, M.T.2    Benoit, B.3
  • 22
    • 38049042414 scopus 로고    scopus 로고
    • A phase II study of cisplatin preceded by a 12-h continuous infusion of concurrent hydroxyurea and cytosine arabinoside (Ara-C) for adult patients with malignant gliomas (Southwest Oncology Group S9149)
    • Swinnen, L. J.; Rankin, C.; Carraway, H.; Albain, K. S.; Townsend, J. J.; Budd, G. T.; Kish, J. A.; Rivkin, S. E.; Blumenthal, D. T. A Phase II Study of Cisplatin Preceded by a 12-h Continuous Infusion of Concurrent Hydroxyurea and Cytosine Arabinoside (Ara-C) for Adult Patients with Malignant Gliomas (Southwest Oncology Group S9149). J. Neurooncol. 2008, 86, 353-358.
    • (2008) J. Neurooncol. , vol.86 , pp. 353-358
    • Swinnen, L.J.1    Rankin, C.2    Carraway, H.3    Albain, K.S.4    Townsend, J.J.5    Budd, G.T.6    Kish, J.A.7    Rivkin, S.E.8    Blumenthal, D.T.9
  • 23
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • stoppini, L.; Buchs, P. A.; Muller, D. A Simple Method for Organotypic Cultures of Nervous Tissue. J. Neurosci. Methods. 1991, 37, 173-182.
    • (1991) J. Neurosci. Methods. , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3
  • 27
    • 0035023997 scopus 로고    scopus 로고
    • Determinants of paclitaxel uptake, accumulation and retention in solid tumors
    • DOI 10.1023/A:1010662413174
    • Jang, S. H.; Wientjes, M. G.; Au, J. L. Determinants of Paclitaxel Uptake, Accumulation and Retention in Solid Tumors. Invest. N. Drugs. 2001, 19, 113-123. (Pubitemid 32423717)
    • (2001) Investigational New Drugs , vol.19 , Issue.2 , pp. 113-123
    • Jang, S.H.1    Wientjes, M.G.2    Au, J.L.-S.3
  • 29
    • 0028133013 scopus 로고
    • NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA
    • Denny, B. J.; Wheelhouse, R. T.; Stevens, M. F.; Tsang, L. L.; Slack, J. A. NMR and Molecular Modeling Investigation of the Mechanism of Activation of the Antitumor Drug Temozolomide and Its Interaction with DNA. Biochemistry 1994, 33, 9045-9051. (Pubitemid 24272851)
    • (1994) Biochemistry , vol.33 , Issue.31 , pp. 9045-9051
    • Denny, B.J.1    Wheelhouse, R.T.2    Stevens, M.F.G.3    Tsang, L.L.H.4    Slack, J.A.5
  • 31
    • 0037428798 scopus 로고    scopus 로고
    • Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids
    • DOI 10.1038/sj.bjc.6600711
    • Gunther, W.; Pawlak, E.; Damasceno, R.; Arnold, H.; Terzis, A. J. Temozolomide Induces Apoptosis and Senescence in Glioma Cells Cultured as Multicellular Spheroids. Br. J. Cancer. 2003, 88, 463-469. (Pubitemid 36308160)
    • (2003) British Journal of Cancer , vol.88 , Issue.3 , pp. 463-469
    • Gunther, W.1    Pawlak, E.2    Damasceno, R.3    Arnold, H.4    Terzis, A.J.5
  • 32
    • 33645105856 scopus 로고    scopus 로고
    • O6-methylguanine dna methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells
    • Hermisson, M.; Klumpp, A.; Wick, W.; Wischhusen, J.; Nagel, G.; Roos, W.; Kaina, B.; Weller, M. O6-Methylguanine DNA Methyltransferase and p53 Status Predict Temozolomide Sensitivity in Human Malignant Glioma Cells. J. Neurochem. 2006, 96, 766-776.
    • (2006) J. Neurochem. , vol.96 , pp. 766-776
    • Hermisson, M.1    Klumpp, A.2    Wick, W.3    Wischhusen, J.4    Nagel, G.5    Roos, W.6    Kaina, B.7    Weller, M.8
  • 34
    • 53049103850 scopus 로고    scopus 로고
    • Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
    • Michelakis, E. D.; Webster, L.; Mackey, J. R. Dichloroacetate (DCA) as a Potential Metabolic-Targeting Therapy for Cancer. Br. J. Cancer. 2008, 99, 989-994.
    • (2008) Br. J. Cancer. , vol.99 , pp. 989-994
    • Michelakis, E.D.1    Webster, L.2    Mackey, J.R.3
  • 36
    • 60549103259 scopus 로고    scopus 로고
    • Spheroid-based drug screen: Considerations and practical approach
    • Friedrich, J.; Seidel, C.; Ebner, R.; Kunz-Schughart, L. A. Spheroid-Based Drug Screen: Considerations and Practical Approach. Nat. Protoc. 2009, 4, 309-324.
    • (2009) Nat. Protoc. , vol.4 , pp. 309-324
    • Friedrich, J.1    Seidel, C.2    Ebner, R.3    Kunz-Schughart, L.A.4
  • 37
    • 37749053847 scopus 로고    scopus 로고
    • Screening for compounds that induce apoptosis of cancer cells grown as multicellular spheroids
    • Herrmann, R.; Fayad, W.; Schwarz, S.; Berndtsson, M.; Linder, S. Screening for Compounds That Induce Apoptosis of Cancer Cells Grown as Multicellular Spheroids. J. Biomol. Screen. 2008, 13, 1-8.
    • (2008) J. Biomol. Screen. , vol.13 , pp. 1-8
    • Herrmann, R.1    Fayad, W.2    Schwarz, S.3    Berndtsson, M.4    Linder, S.5
  • 38
    • 16544380146 scopus 로고    scopus 로고
    • The use of 3-D cultures for high-throughput screening: The multicellular spheroid model
    • Kunz-Schughart, L. A.; Freyer, J. P.; Hofstaedter, F.; Ebner, R. The Use of 3-D Cultures for High-Throughput Screening: The Multicellular Spheroid Model. J. Biomol. Screen. 2004, 9, 273-285.
    • (2004) J. Biomol. Screen. , vol.9 , pp. 273-285
    • Kunz-Schughart, L.A.1    Freyer, J.P.2    Hofstaedter, F.3    Ebner, R.4
  • 39
    • 79952000716 scopus 로고    scopus 로고
    • 3D models of epithelial-mesenchymal transition in breast cancer metastasis: High-throughput screening assay development, validation, and pilot screen
    • Li, Q.; Chen, C.; Kapadia, A.; Zhou, Q.; Harper, M. K.; Schaack, J.; LaBarbera, D. V. 3D Models of Epithelial-Mesenchymal Transition in Breast Cancer Metastasis: High-Throughput Screening Assay Development, Validation, and Pilot Screen. J. Biomol. Screen. 2011, 16, 141-154.
    • (2011) J. Biomol. Screen. , vol.16 , pp. 141-154
    • Li, Q.1    Chen, C.2    Kapadia, A.3    Zhou, Q.4    Harper, M.K.5    Schaack, J.6    LaBarbera, D.V.7
  • 40
    • 23244447397 scopus 로고    scopus 로고
    • Development of an in vitro multicellular tumor spheroid model using microencapsulation and its application in anticancer drug screening and testing
    • DOI 10.1021/bp050003l
    • Zhang, X.; Wang, W.; Yu, W.; Xie, Y.; Zhang, Y.; Ma, X. Development of an In Vitro Multicellular Tumor Spheroid Model Using Microencapsulation and Its Application in Anticancer Drug Screening and Testing. Biotechnol Prog. 2005, 21, 1289-1296. (Pubitemid 41099602)
    • (2005) Biotechnology Progress , vol.21 , Issue.4 , pp. 1289-1296
    • Zhang, X.1    Wang, W.2    Yu, W.3    Xie, Y.4    Zhang, X.5    Zhang, Y.6    Ma, X.7


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