-
1
-
-
77957273984
-
Animal models of neuropsychiatric disorders
-
E.J. Nestler, and S.E. Hyman Animal models of neuropsychiatric disorders Nat Neurosci 13 2010 1161 1169
-
(2010)
Nat Neurosci
, vol.13
, pp. 1161-1169
-
-
Nestler, E.J.1
Hyman, S.E.2
-
2
-
-
36248966518
-
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
-
DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
-
K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872 (Pubitemid 350138099)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
3
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
I.H. Park, N. Arora, H. Huo, N. Maherali, T. Ahfeldt, A. Shimamura, M.W. Lensch, C. Cowan, K. Hochedlinger, and G.Q. Daley Disease-specific induced pluripotent stem cells Cell 134 2008 877 886
-
(2008)
Cell
, vol.134
, pp. 877-886
-
-
Park, I.H.1
Arora, N.2
Huo, H.3
Maherali, N.4
Ahfeldt, T.5
Shimamura, A.6
Lensch, M.W.7
Cowan, C.8
Hochedlinger, K.9
Daley, G.Q.10
-
4
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
T. Vierbuchen, A. Ostermeier, Z.P. Pang, Y. Kokubu, T.C. Sudhof, and M. Wernig Direct conversion of fibroblasts to functional neurons by defined factors Nature 463 2010 1035 1041
-
(2010)
Nature
, vol.463
, pp. 1035-1041
-
-
Vierbuchen, T.1
Ostermeier, A.2
Pang, Z.P.3
Kokubu, Y.4
Sudhof, T.C.5
Wernig, M.6
-
5
-
-
79956357347
-
Direct reprogramming of mouse fibroblasts to neural progenitors
-
J. Kim, J.A. Efe, S. Zhu, M. Talantova, X. Yuan, S. Wang, S.A. Lipton, K. Zhang, and S. Ding Direct reprogramming of mouse fibroblasts to neural progenitors Proc Natl Acad Sci USA 108 2011 7838 7843
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 7838-7843
-
-
Kim, J.1
Efe, J.A.2
Zhu, S.3
Talantova, M.4
Yuan, X.5
Wang, S.6
Lipton, S.A.7
Zhang, K.8
Ding, S.9
-
6
-
-
79953181303
-
Self-renewal induced efficiently, safely, and effective therapeutically with one regulatable gene in a human somatic progenitor cell
-
K.S. Kim, H.J. Lee, H.S. Jeong, J. Li, Y.D. Teng, R.L. Sidman, E.Y. Snyder, and S.U. Kim Self-renewal induced efficiently, safely, and effective therapeutically with one regulatable gene in a human somatic progenitor cell Proc Natl Acad Sci USA 108 2011 4876 4881
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 4876-4881
-
-
Kim, K.S.1
Lee, H.J.2
Jeong, H.S.3
Li, J.4
Teng, Y.D.5
Sidman, R.L.6
Snyder, E.Y.7
Kim, S.U.8
-
7
-
-
79952710923
-
Induced pluripotent stem cells: A new revolution for clinical neurology?
-
V.B. Mattis, and C.N. Svendsen Induced pluripotent stem cells: a new revolution for clinical neurology? Lancet Neurol 10 2011 383 394
-
(2011)
Lancet Neurol
, vol.10
, pp. 383-394
-
-
Mattis, V.B.1
Svendsen, C.N.2
-
8
-
-
77957670482
-
Differentiated parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in parkinsonian rats
-
G. Hargus, O. Cooper, M. Deleidi, A. Levy, K. Lee, E. Marlow, A. Yow, F. Soldner, D. Hockemeyer, and P.J. Hallett Differentiated parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in parkinsonian rats Proc Natl Acad Sci USA 107 2010 15921 15926
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15921-15926
-
-
Hargus, G.1
Cooper, O.2
Deleidi, M.3
Levy, A.4
Lee, K.5
Marlow, E.6
Yow, A.7
Soldner, F.8
Hockemeyer, D.9
Hallett, P.J.10
-
9
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
A.D. Ebert, J. Yu, F.F. Rose Jr., V.B. Mattis, C.L. Lorson, J.A. Thomson, and C.N. Svendsen Induced pluripotent stem cells from a spinal muscular atrophy patient Nature 457 2009 277 280
-
(2009)
Nature
, vol.457
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose Jr., F.F.3
Mattis, V.B.4
Lorson, C.L.5
Thomson, J.A.6
Svendsen, C.N.7
-
10
-
-
70349301819
-
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
-
G. Lee, E.P. Papapetrou, H. Kim, S.M. Chambers, M.J. Tomishima, C.A. Fasano, Y.M. Ganat, J. Menon, F. Shimizu, and A. Viale Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs Nature 461 2009 402 406
-
(2009)
Nature
, vol.461
, pp. 402-406
-
-
Lee, G.1
Papapetrou, E.P.2
Kim, H.3
Chambers, S.M.4
Tomishima, M.J.5
Fasano, C.A.6
Ganat, Y.M.7
Menon, J.8
Shimizu, F.9
Viale, A.10
-
11
-
-
78549247463
-
L1 retrotransposition in neurons is modulated by mecp2
-
A.R. Muotri, M.C. Marchetto, N.G. Coufal, R. Oefner, G. Yeo, K. Nakashima, and F.H. Gage L1 retrotransposition in neurons is modulated by mecp2 Nature 468 2010 443 446
-
(2010)
Nature
, vol.468
, pp. 443-446
-
-
Muotri, A.R.1
Marchetto, M.C.2
Coufal, N.G.3
Oefner, R.4
Yeo, G.5
Nakashima, K.6
Gage, F.H.7
-
12
-
-
78149488365
-
A model for neural development and treatment of rett syndrome using human induced pluripotent stem cells
-
M.C. Marchetto, C. Carromeu, A. Acab, D. Yu, G.W. Yeo, Y. Mu, G. Chen, F.H. Gage, and A.R. Muotri A model for neural development and treatment of rett syndrome using human induced pluripotent stem cells Cell 143 2010 527 539
-
(2010)
Cell
, vol.143
, pp. 527-539
-
-
Marchetto, M.C.1
Carromeu, C.2
Acab, A.3
Yu, D.4
Yeo, G.W.5
Mu, Y.6
Chen, G.7
Gage, F.H.8
Muotri, A.R.9
-
13
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
F. Soldner, D. Hockemeyer, C. Beard, Q. Gao, G.W. Bell, E.G. Cook, G. Hargus, A. Blak, O. Cooper, and M. Mitalipova Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors Cell 136 2009 964 977
-
(2009)
Cell
, vol.136
, pp. 964-977
-
-
Soldner, F.1
Hockemeyer, D.2
Beard, C.3
Gao, Q.4
Bell, G.W.5
Cook, E.G.6
Hargus, G.7
Blak, A.8
Cooper, O.9
Mitalipova, M.10
-
14
-
-
79952172335
-
Lrrk2 mutant ipsc-derived da neurons demonstrate increased susceptibility to oxidative stress
-
H.N. Nguyen, B. Byers, B. Cord, A. Shcheglovitov, J. Byrne, P. Gujar, K. Kee, B. Schule, R.E. Dolmetsch, and W. Langston Lrrk2 mutant ipsc-derived da neurons demonstrate increased susceptibility to oxidative stress Cell Stem Cell 8 2011 267 280
-
(2011)
Cell Stem Cell
, vol.8
, pp. 267-280
-
-
Nguyen, H.N.1
Byers, B.2
Cord, B.3
Shcheglovitov, A.4
Byrne, J.5
Gujar, P.6
Kee, K.7
Schule, B.8
Dolmetsch, R.E.9
Langston, W.10
-
15
-
-
79955786943
-
Mitochondrial parkin recruitment is impaired in neurons derived from mutant pink1 induced pluripotent stem cells
-
P. Seibler, J. Graziotto, H. Jeong, F. Simunovic, C. Klein, and D. Krainc Mitochondrial parkin recruitment is impaired in neurons derived from mutant pink1 induced pluripotent stem cells J Neurosci 31 2011 5970 5976
-
(2011)
J Neurosci
, vol.31
, pp. 5970-5976
-
-
Seibler, P.1
Graziotto, J.2
Jeong, H.3
Simunovic, F.4
Klein, C.5
Krainc, D.6
-
16
-
-
79955884485
-
Modelling schizophrenia using human induced pluripotent stem cells
-
K.J. Brennand, A. Simone, J. Jou, C. Gelboin-Burkhart, N. Tran, S. Sangar, Y. Li, Y. Mu, G. Chen, and D. Yu Modelling schizophrenia using human induced pluripotent stem cells Nature 473 2011 221 225
-
(2011)
Nature
, vol.473
, pp. 221-225
-
-
Brennand, K.J.1
Simone, A.2
Jou, J.3
Gelboin-Burkhart, C.4
Tran, N.5
Sangar, S.6
Li, Y.7
Mu, Y.8
Chen, G.9
Yu, D.10
-
17
-
-
79953048441
-
Integration-free induced pluripotent stem cells derived from schizophrenia patients with a disc1 mutation
-
C.H. Chiang, Y. Su, Z. Wen, N. Yoritomo, C.A. Ross, R.L. Margolis, H. Song, and G.L. Ming Integration-free induced pluripotent stem cells derived from schizophrenia patients with a disc1 mutation Mol Psychiatry 16 2011 358 360
-
(2011)
Mol Psychiatry
, vol.16
, pp. 358-360
-
-
Chiang, C.H.1
Su, Y.2
Wen, Z.3
Yoritomo, N.4
Ross, C.A.5
Margolis, R.L.6
Song, H.7
Ming, G.L.8
-
18
-
-
77957960817
-
Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression
-
J. Huang, R.H. Perlis, P.H. Lee, A.J. Rush, M. Fava, G.S. Sachs, J. Lieberman, S.P. Hamilton, P. Sullivan, and P. Sklar Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression Am J Psychiatry 167 2010 1254 1263
-
(2010)
Am J Psychiatry
, vol.167
, pp. 1254-1263
-
-
Huang, J.1
Perlis, R.H.2
Lee, P.H.3
Rush, A.J.4
Fava, M.5
Sachs, G.S.6
Lieberman, J.7
Hamilton, S.P.8
Sullivan, P.9
Sklar, P.10
-
19
-
-
79955596140
-
Disc1-dependent switch from progenitor proliferation to migration in the developing cortex
-
K. Ishizuka, A. Kamiya, E.C. Oh, H. Kanki, S. Seshadri, J.F. Robinson, H. Murdoch, A.J. Dunlop, K.I. Kubo, and K. Furukori Disc1-dependent switch from progenitor proliferation to migration in the developing cortex Nature 473 2011 92 96
-
(2011)
Nature
, vol.473
, pp. 92-96
-
-
Ishizuka, K.1
Kamiya, A.2
Oh, E.C.3
Kanki, H.4
Seshadri, S.5
Robinson, J.F.6
Murdoch, H.7
Dunlop, A.J.8
Kubo, K.I.9
Furukori, K.10
-
20
-
-
78650971216
-
Dynamic changes in the copy number of pluripotency and cell proliferation genes in human escs and ipscs during reprogramming and time in culture
-
L.C. Laurent, I. Ulitsky, I. Slavin, H. Tran, A. Schork, R. Morey, C. Lynch, J.V. Harness, S. Lee, and M.J. Barrero Dynamic changes in the copy number of pluripotency and cell proliferation genes in human escs and ipscs during reprogramming and time in culture Cell Stem Cell 8 2011 106 118
-
(2011)
Cell Stem Cell
, vol.8
, pp. 106-118
-
-
Laurent, L.C.1
Ulitsky, I.2
Slavin, I.3
Tran, H.4
Schork, A.5
Morey, R.6
Lynch, C.7
Harness, J.V.8
Lee, S.9
Barrero, M.J.10
-
21
-
-
79952261648
-
Stem cells: The dark side of induced pluripotency
-
M.F. Pera Stem cells: the dark side of induced pluripotency Nature 471 2011 46 47
-
(2011)
Nature
, vol.471
, pp. 46-47
-
-
Pera, M.F.1
-
22
-
-
84873337576
-
Characterization of human huntington's disease cell model from induced pluripotent stem cells
-
N. Zhang, M.C. An, D. Montoro, and L.M. Ellerby Characterization of human huntington's disease cell model from induced pluripotent stem cells PLoS Curr 2 2010
-
(2010)
PLoS Curr
, vol.2
-
-
Zhang, N.1
An, M.C.2
Montoro, D.3
Ellerby, L.M.4
-
23
-
-
78049303170
-
Induced pluripotent stem cell models of the genomic imprinting disorders angelman and prader-willi syndromes
-
S.J. Chamberlain, P.F. Chen, K.Y. Ng, F. Bourgois-Rocha, F. Lemtiri-Chlieh, E.S. Levine, and M. Lalande Induced pluripotent stem cell models of the genomic imprinting disorders angelman and prader-willi syndromes Proc Natl Acad Sci USA 107 2010 17668 17673
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 17668-17673
-
-
Chamberlain, S.J.1
Chen, P.F.2
Ng, K.Y.3
Bourgois-Rocha, F.4
Lemtiri-Chlieh, F.5
Levine, E.S.6
Lalande, M.7
-
24
-
-
79551665440
-
A functionally characterized test set of human induced pluripotent stem cells
-
G.L. Boulting, E. Kiskinis, G.F. Croft, M.W. Amoroso, D.H. Oakley, B.J. Wainger, D.J. Williams, D.J. Kahler, M. Yamaki, and L. Davidow A functionally characterized test set of human induced pluripotent stem cells Nat Biotechnol 29 2011 279 286
-
(2011)
Nat Biotechnol
, vol.29
, pp. 279-286
-
-
Boulting, G.L.1
Kiskinis, E.2
Croft, G.F.3
Amoroso, M.W.4
Oakley, D.H.5
Wainger, B.J.6
Williams, D.J.7
Kahler, D.J.8
Yamaki, M.9
Davidow, L.10
-
25
-
-
77957334627
-
Identification and classification of chromosomal aberrations in human induced pluripotent stem cells
-
Y. Mayshar, U. Ben-David, N. Lavon, J.C. Biancotti, B. Yakir, A.T. Clark, K. Plath, W.E. Lowry, and N. Benvenisty Identification and classification of chromosomal aberrations in human induced pluripotent stem cells Cell Stem Cell 7 2010 521 531
-
(2010)
Cell Stem Cell
, vol.7
, pp. 521-531
-
-
Mayshar, Y.1
Ben-David, U.2
Lavon, N.3
Biancotti, J.C.4
Yakir, B.5
Clark, A.T.6
Plath, K.7
Lowry, W.E.8
Benvenisty, N.9
-
26
-
-
78650752402
-
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
-
J.M. Polo, S. Liu, M.E. Figueroa, W. Kulalert, S. Eminli, K.Y. Tan, E. Apostolou, M. Stadtfeld, Y. Li, and T. Shioda Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells Nat Biotechnol 28 2010 848 855
-
(2010)
Nat Biotechnol
, vol.28
, pp. 848-855
-
-
Polo, J.M.1
Liu, S.2
Figueroa, M.E.3
Kulalert, W.4
Eminli, S.5
Tan, K.Y.6
Apostolou, E.7
Stadtfeld, M.8
Li, Y.9
Shioda, T.10
-
27
-
-
77955449906
-
Epigenetic memory in induced pluripotent stem cells
-
K. Kim, A. Doi, B. Wen, K. Ng, R. Zhao, P. Cahan, J. Kim, M.J. Aryee, H. Ji, and L.I. Ehrlich Epigenetic memory in induced pluripotent stem cells Nature 467 2010 285 290
-
(2010)
Nature
, vol.467
, pp. 285-290
-
-
Kim, K.1
Doi, A.2
Wen, B.3
Ng, K.4
Zhao, R.5
Cahan, P.6
Kim, J.7
Aryee, M.J.8
Ji, H.9
Ehrlich, L.I.10
-
28
-
-
77749279749
-
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
-
B.Y. Hu, J.P. Weick, J. Yu, L.X. Ma, X.Q. Zhang, J.A. Thomson, and S.C. Zhang Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency Proc Natl Acad Sci USA 107 2010 4335 4340
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4335-4340
-
-
Hu, B.Y.1
Weick, J.P.2
Yu, J.3
Ma, L.X.4
Zhang, X.Q.5
Thomson, J.A.6
Zhang, S.C.7
-
29
-
-
79952601242
-
Investigating synapse formation and function using human pluripotent stem cell-derived neurons
-
J.E. Kim, M.L. O'Sullivan, C.A. Sanchez, M. Hwang, M.A. Israel, K. Brennand, T.J. Deerinck, L.S. Goldstein, F.H. Gage, M.H. Ellisman, and A. Ghosh Investigating synapse formation and function using human pluripotent stem cell-derived neurons Proc Natl Acad Sci USA 108 2011 3005 3010
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3005-3010
-
-
Kim, J.E.1
O'Sullivan, M.L.2
Sanchez, C.A.3
Hwang, M.4
Israel, M.A.5
Brennand, K.6
Deerinck, T.J.7
Goldstein, L.S.8
Gage, F.H.9
Ellisman, M.H.10
Ghosh, A.11
-
30
-
-
79955574166
-
Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy
-
S.E. Howden, A. Gore, Z. Li, H.L. Fung, B.S. Nisler, J. Nie, G. Chen, B.E. McIntosh, D.R. Gulbranson, and N.R. Diol Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy Proc Natl Acad Sci USA 108 2011 6537 6542
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 6537-6542
-
-
Howden, S.E.1
Gore, A.2
Li, Z.3
Fung, H.L.4
Nisler, B.S.5
Nie, J.6
Chen, G.7
McIntosh, B.E.8
Gulbranson, D.R.9
Diol, N.R.10
-
31
-
-
79957807595
-
Immunogenicity of induced pluripotent stem cells
-
T. Zhao, Z.N. Zhang, Z. Rong, and Y. Xu Immunogenicity of induced pluripotent stem cells Nature 474 2011 212 215
-
(2011)
Nature
, vol.474
, pp. 212-215
-
-
Zhao, T.1
Zhang, Z.N.2
Rong, Z.3
Xu, Y.4
-
32
-
-
79955464098
-
The use of induced pluripotent stem cells in drug development
-
H. Inoue, and S. Yamanaka The use of induced pluripotent stem cells in drug development Clin Pharmacol Ther 89 2011 655 661
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 655-661
-
-
Inoue, H.1
Yamanaka, S.2
-
33
-
-
79952292990
-
Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells
-
S.H. Yuan, J. Martin, J. Elia, J. Flippin, R.I. Paramban, M.P. Hefferan, J.G. Vidal, Y. Mu, R.L. Killian, and M.A. Israel Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells PLoS ONE 6 2011 e17540
-
(2011)
PLoS ONE
, vol.6
, pp. 17540
-
-
Yuan, S.H.1
Martin, J.2
Elia, J.3
Flippin, J.4
Paramban, R.I.5
Hefferan, M.P.6
Vidal, J.G.7
Mu, Y.8
Killian, R.L.9
Israel, M.A.10
|