Caffeic acid 3,4-dihydroxy-phenethyl ester suppresses receptor activator of NF-κB ligand-induced osteoclastogenesis and prevents ovariectomy-induced bone loss through inhibition of mitogen-activated protein kinase/activator protein 1 and Ca2+-nuclear factor of activated T-cells cytoplasmic 1 signaling pathways

Journal of Bone and Mineral Research

Volumn 27, Issue 6, 2012, Pages 1298-1308

  Wu, Xian ^a   Li, Zhenxi ^a   Yang, Zhengfeng ^a   Zheng, Chunbing ^a   Jing, Ji ^a   Chen, Yihua ^a   Ye, Xiyun ^a   Lian, Xiaoyuan ^a   Qiu, Wenwei ^a   Yang, Fan ^a   Tang, Jie ^a   Xiao, Jianru ^a   Liu, Mingyao ^a,b   Luo, Jian ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

Ca2+ NFATc1; CAFFEIC ACID; MAPK AP 1; MENOPAUSE; OSTEOPOROSIS

Indexed keywords

CAFFEIC ACID PHENETHYL ESTER; CALCIUM ION; CATHEPSIN K; COLONY STIMULATING FACTOR 1; I KAPPA B; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN KINASE B; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; GROWTH INHIBITION; INHIBITION KINETICS; MONOCYTE; MOUSE; NONHUMAN; ONCOGENE C FOS; ONCOGENE SRC; OSTEOCLASTOGENESIS; OSTEOLYSIS; OSTEOSARCOMA; OVARIECTOMY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ACTINS; ANIMALS; BIOLOGICAL MARKERS; BONE MARROW CELLS; BONE RESORPTION; CAFFEIC ACIDS; CALCIUM; CALCIUM SIGNALING; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; OSTEOBLASTS; OSTEOCLASTS; OSTEOGENESIS; OVARIECTOMY; RANK LIGAND; TRANSCRIPTION FACTOR AP-1;

EID: 84861316067     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1576     Document Type: Article

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