Computational modeling on the recognition of the HRE motif by HIF-1: Molecular docking and molecular dynamics studies

Journal of Molecular Modeling

Volumn 18, Issue 5, 2012, Pages 1691-1700

  Sokkar, Pandian ^a   Sathis, Vani ^a   Ramachandran, Murugesan ^a  

^a MADURAI KAMARAJ UNIVERSITY   (India)

Author keywords

DNA recognition; Homology modeling; Hypoxia responsive element; Hypoxia inducible factor 1; Molecular dynamics

Indexed keywords

DNA; HYPOXIA INDUCIBLE FACTOR 1; TRANSCRIPTION FACTOR; VASCULOTROPIN;

ARTICLE; DIMERIZATION; DNA PROTEIN COMPLEX; DNA RESPONSIVE ELEMENT; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; SIMULATION;

AMINO ACID SEQUENCE; AMINO ACIDS; ANOXIA; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; BINDING SITES; DIMERIZATION; DNA-BINDING PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RESPONSE ELEMENTS; SACCHAROMYCES CEREVISIAE PROTEINS; STRUCTURAL HOMOLOGY, PROTEIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WATER;

EID: 84861232290     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-011-1150-0     Document Type: Article

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