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Volumn 26, Issue 6, 2012, Pages 977-988

Peroxisome proliferator-activated receptor γ decouples fatty acid uptake from lipid inhibition of insulin signaling in skeletal muscle

Author keywords

Ligands; Nuclear receptors; PPAR ; Rosiglitazone

Indexed keywords

CD36 ANTIGEN; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B;

EID: 84861215127     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-1253     Document Type: Article
Times cited : (20)

References (51)
  • 1
    • 77949397703 scopus 로고    scopus 로고
    • The association between the peroxisome proliferator-activated receptor-γ2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: A HuGE review and meta-analysis
    • Gouda HN, Sagoo GS, Harding AH, Yates J, Sandhu MS, Higgins JP 2010 The association between the peroxisome proliferator-activated receptor-γ2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis. Am J Epidemiol 171:645-655
    • (2010) Am J Epidemiol , vol.171 , pp. 645-655
    • Gouda, H.N.1    Sagoo, G.S.2    Harding, A.H.3    Yates, J.4    Sandhu, M.S.5    Higgins, J.P.6
  • 3
    • 0034064359 scopus 로고    scopus 로고
    • Distribution of peroxisome proliferator-activated receptors (PPARs) in human skeletal muscle and adipose tissue: Relation to insulin action
    • Loviscach M, Rehman N, Carter L, Mudaliar S, Mohadeen P, Ciaraldi TP, Veerkamp JH, Henry RR 2000 Distribution of peroxisome proliferator-activated receptors (PPARs) in human skeletal muscle and adipose tissue: relation to insulin action. Diabetologia 43:304-311
    • (2000) Diabetologia , vol.43 , pp. 304-311
    • Loviscach, M.1    Rehman, N.2    Carter, L.3    Mudaliar, S.4    Mohadeen, P.5    Ciaraldi, T.P.6    Veerkamp, J.H.7    Henry, R.R.8
  • 4
    • 0032006547 scopus 로고    scopus 로고
    • Skeletal muscle peroxisome proliferatoractivated receptor- expression in obesity and noninsulin-dependent diabetes mellitus
    • Kruszynska YT, Mukherjee R, Jow L, Dana S, Paterniti JR, Olefsky JM 1998 Skeletal muscle peroxisome proliferatoractivated receptor- expression in obesity and noninsulin-dependent diabetes mellitus. J Clin Invest 101:543-548
    • (1998) J Clin Invest , vol.101 , pp. 543-548
    • Kruszynska, Y.T.1    Mukherjee, R.2    Jow, L.3    Dana, S.4    Paterniti, J.R.5    Olefsky, J.M.6
  • 9
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: The diverse biology of PPARγ
    • Tontonoz P, Spiegelman BM 2008 Fat and beyond: the diverse biology of PPARγ. Annu Rev Biochem 77:289-312
    • (2008) Annu Rev Biochem , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 11
    • 2942722772 scopus 로고    scopus 로고
    • Basic disturbances in skeletal muscle fatty acid metabolism in obesity and type 2 diabetes mellitus
    • Blaak EE 2004 Basic disturbances in skeletal muscle fatty acid metabolism in obesity and type 2 diabetes mellitus. Proc Nutr Soc 63:323-330
    • (2004) Proc Nutr Soc , vol.63 , pp. 323-330
    • Blaak, E.E.1
  • 12
    • 0033578604 scopus 로고    scopus 로고
    • Muscle-specific overexpression of FAT/ CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin
    • Ibrahimi A, Bonen A, Blinn WD, Hajri T, Li X, Zhong K, Cameron R, Abumrad NA 1999 Muscle-specific overexpression of FAT/ CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J Biol Chem 274:26761-26766
    • (1999) J Biol Chem , vol.274 , pp. 26761-26766
    • Ibrahimi, A.1    Bonen, A.2    Blinn, W.D.3    Hajri, T.4    Li, X.5    Zhong, K.6    Cameron, R.7    Abumrad, N.A.8
  • 15
    • 0346003777 scopus 로고    scopus 로고
    • Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor γ1 (PPARγ1) overexpression
    • Yu S, Matsusue K, Kashireddy P, Cao WQ, Yeldandi V, Yeldandi AV, Rao MS, Gonzalez FJ, Reddy JK 2003 Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor γ1 (PPARγ1) overexpression. J Biol Chem 278:498-505
    • (2003) J Biol Chem , vol.278 , pp. 498-505
    • Yu, S.1    Matsusue, K.2    Kashireddy, P.3    Cao, W.Q.4    Yeldandi, V.5    Yeldandi, A.V.6    Rao, M.S.7    Gonzalez, F.J.8    Reddy, J.K.9
  • 16
    • 0033661363 scopus 로고    scopus 로고
    • A model to explore the interaction between muscle insulin resistance and β-cell dysfunction in the development of type 2 diabetes
    • Mauvais-Jarvis F, Virkamaki A, Michael MD, Winnay JN, Zisman A, Kulkarni RN, Kahn CR 2000 A model to explore the interaction between muscle insulin resistance and β-cell dysfunction in the development of type 2 diabetes. Diabetes 49:2126-2134
    • (2000) Diabetes , vol.49 , pp. 2126-2134
    • Mauvais-Jarvis, F.1    Virkamaki, A.2    Michael, M.D.3    Winnay, J.N.4    Zisman, A.5    Kulkarni, R.N.6    Kahn, C.R.7
  • 17
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J, Lees M, Sloane Stanley GH 1957 A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226:497-509
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane, S.G.H.3
  • 18
    • 0034790836 scopus 로고    scopus 로고
    • Analysis and quantitation of ceramide
    • Signorelli P, Hannun YA 2002 Analysis and quantitation of ceramide. Methods Enzymol 345:275-294
    • (2002) Methods Enzymol , vol.345 , pp. 275-294
    • Signorelli, P.1    Hannun, Y.A.2
  • 19
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ 1959 A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37:911-917
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 27
    • 4344685789 scopus 로고    scopus 로고
    • CD36 in myocytes channels fatty acids to a lipase-accessible triglyceride pool that is related to cell lipid and insulin responsiveness
    • Bastie CC, Hajri T, Drover VA, Grimaldi PA, Abumrad NA 2004 CD36 in myocytes channels fatty acids to a lipase-accessible triglyceride pool that is related to cell lipid and insulin responsiveness. Diabetes 53:2209-2216
    • (2004) Diabetes , vol.53 , pp. 2209-2216
    • Bastie, C.C.1    Hajri, T.2    Drover, V.A.3    Grimaldi, P.A.4    Abumrad, N.A.5
  • 29
    • 0033199841 scopus 로고    scopus 로고
    • Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: Identification of five sites of phosphorylation in vivo
    • Casamayor A, Morrice NA, Alessi DR 1999 Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo. Biochem J 342(Pt 2):287-292
    • (1999) Biochem J , vol.342 , Issue.PART. 2 , pp. 287-292
    • Casamayor, A.1    Morrice, N.A.2    Alessi, D.R.3
  • 30
    • 78650407231 scopus 로고    scopus 로고
    • Identification of PP2A complexes and pathways involved in cell transformation
    • Sablina AA, Hector M, Colpaert N, Hahn WC 2010 Identification of PP2A complexes and pathways involved in cell transformation. Cancer Res 70:10474-10484
    • (2010) Cancer Res , vol.70 , pp. 10474-10484
    • Sablina, A.A.1    Hector, M.2    Colpaert, N.3    Hahn, W.C.4
  • 31
    • 0038242819 scopus 로고    scopus 로고
    • TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
    • Du K, Herzig S, Kulkarni RN, Montminy M 2003 TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science 300:1574-1577
    • (2003) Science , vol.300 , pp. 1574-1577
    • Du, K.1    Herzig, S.2    Kulkarni, R.N.3    Montminy, M.4
  • 32
    • 59049100254 scopus 로고    scopus 로고
    • Protein kinase C (PKC)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance
    • Wang C, Liu M, Riojas RA, Xin X, Gao Z, Zeng R, Wu J, Dong LQ, Liu F 2009 Protein kinase Co (PKCo)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance. J Biol Chem 284:2038-2044
    • (2009) J Biol Chem , vol.284 , pp. 2038-2044
    • Wang, C.1    Liu, M.2    Riojas, R.A.3    Xin, X.4    Gao, Z.5    Zeng, R.6    Wu, J.7    Dong, L.Q.8    Liu, F.9
  • 34
    • 0027946529 scopus 로고
    • Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus
    • Kelley DE, Simoneau JA 1994 Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus. J Clin Invest 94:2349-2356
    • (1994) J Clin Invest , vol.94 , pp. 2349-2356
    • Kelley, D.E.1    Simoneau, J.A.2
  • 36
    • 0037013201 scopus 로고    scopus 로고
    • Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator-activated receptor α and γ ligands
    • Sato O, Kuriki C, Fukui Y, Motojima K 2002 Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator-activated receptor α and γ ligands. J Biol Chem 277:15703-15711
    • (2002) J Biol Chem , vol.277 , pp. 15703-15711
    • Sato, O.1    Kuriki, C.2    Fukui, Y.3    Motojima, K.4
  • 37
    • 0033548216 scopus 로고    scopus 로고
    • Identification of a functional peroxisome proliferator-responsive element in the murine fatty acid transport protein gene
    • Frohnert BI, Hui TY, Bernlohr DA 1999 Identification of a functional peroxisome proliferator-responsive element in the murine fatty acid transport protein gene. J Biol Chem 274:3970-3977
    • (1999) J Biol Chem , vol.274 , pp. 3970-3977
    • Frohnert, B.I.1    Hui, T.Y.2    Bernlohr, D.A.3
  • 39
    • 11244348979 scopus 로고    scopus 로고
    • PPAR-gamma expression modulates insulin sensitivity in C2C12 skeletal muscle cells
    • Verma NK, Singh J, Dey CS 2004 PPAR-gamma expression modulates insulin sensitivity in C2C12 skeletal muscle cells. Br J Pharmacol 143:1006-1013
    • (2004) Br J Pharmacol , vol.143 , pp. 1006-1013
    • Verma, N.K.1    Singh, J.2    Dey, C.S.3
  • 40
    • 0035487315 scopus 로고    scopus 로고
    • A role for protein phosphatase 2A-like activity, but not atypical protein kinase C, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate
    • Cazzolli R, Carpenter L, Biden TJ, Schmitz-Peiffer C 2001 A role for protein phosphatase 2A-like activity, but not atypical protein kinase C, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate. Diabetes 50:2210-2218
    • (2001) Diabetes , vol.50 , pp. 2210-2218
    • Cazzolli, R.1    Carpenter, L.2    Biden, T.J.3    Schmitz-Peiffer, C.4
  • 41
    • 69049098306 scopus 로고    scopus 로고
    • The Randle cycle revisited: A new head for an old hat
    • Hue L, Taegtmeyer H 2009 The Randle cycle revisited: a new head for an old hat. Am J Physiol Endocrinol Metab 297:E578-E591
    • (2009) Am J Physiol Endocrinol Metab , vol.297 , pp. 578-591
    • Hue, L.1    Taegtmeyer, H.2
  • 43
    • 34047101856 scopus 로고    scopus 로고
    • Rosiglitazone inhibits acyl-CoA synthetase activity and fatty acid partitioning to diacylglycerol and triacylglycerol via a peroxisome proliferator-activated receptor-γ-independent mechanism in human arterial smooth muscle cells and macrophages
    • Askari B, Kanter JE, Sherrid AM, Golej DL, Bender AT, Liu J, Hsueh WA, Beavo JA, Coleman RA, Bornfeldt KE 2007 Rosiglitazone inhibits acyl-CoA synthetase activity and fatty acid partitioning to diacylglycerol and triacylglycerol via a peroxisome proliferator-activated receptor-γ-independent mechanism in human arterial smooth muscle cells and macrophages. Diabetes 56:1143-1152
    • (2007) Diabetes , vol.56 , pp. 1143-1152
    • Askari, B.1    Kanter, J.E.2    Sherrid, A.M.3    Golej, D.L.4    Bender, A.T.5    Liu, J.6    Hsueh, W.A.7    Beavo, J.A.8    Coleman, R.A.9    Bornfeldt, K.E.10
  • 45
    • 0035491792 scopus 로고    scopus 로고
    • Direct thiazolidinedione action on isolated rat skeletal muscle fuel handling is independent of peroxisome proliferator-activated receptor-γ-mediated changes in gene expression
    • Brunmair B, Gras F, Neschen S, Roden M, Wagner L, Waldhäusl W, Fürnsinn C 2001 Direct thiazolidinedione action on isolated rat skeletal muscle fuel handling is independent of peroxisome proliferator-activated receptor-γ-mediated changes in gene expression. Diabetes 50:2309-2315
    • (2001) Diabetes , vol.50 , pp. 2309-2315
    • Brunmair, B.1    Gras, F.2    Neschen, S.3    Roden, M.4    Wagner, L.5    Waldhäusl, W.6    Fürnsinn, C.7
  • 49
    • 77955560424 scopus 로고    scopus 로고
    • Increased levels of peroxisome proliferator-activated receptorγ, coactivator 1α(PGC-1α) improvelipidutilisation,insulinsignallingandglucosetransport in skeletal muscle of lean and insulin-resistant obese Zucker rats
    • Benton CR, Holloway GP, Han XX, Yoshida Y, Snook LA, Lally J, Glatz JF, Luiken JJ, Chabowski A, Bonen A 2010 Increased levels of peroxisome proliferator-activated receptor γ, coactivator 1α(PGC-1α) improvelipidutilisation,insulinsignallingandglucosetransport in skeletal muscle of lean and insulin-resistant obese Zucker rats. Diabetologia 53:2008-2019
    • (2010) Diabetologia , vol.53 , pp. 2008-2019
    • Benton, C.R.1    Holloway, G.P.2    Han, X.X.3    Yoshida, Y.4    Snook, L.A.5    Lally, J.6    Glatz, J.F.7    Luiken, J.J.8    Chabowski, A.9    Bonen, A.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.