메뉴 건너뛰기




Volumn 43, Issue 3, 2000, Pages 304-311

Distribution of peroxisome proliferator-activated receptors (PPARs) in human skeletal muscle and adipose tissue: Relation to insulin action

Author keywords

Adipose tissue; Human; Insulin resistance; Obesity; PPAR ; PPAR ; PPAR ; Protein; Skeletal muscle; Type II diabetes

Indexed keywords

BIGUANIDE; INSULIN; ORAL ANTIDIABETIC AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; SULFONYLUREA;

EID: 0034064359     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250050048     Document Type: Article
Times cited : (157)

References (41)
  • 1
    • 0030602866 scopus 로고    scopus 로고
    • The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation
    • 1. Schoonjans K, Staels B, Auwerx J (1996) The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation. Biochim Biophys Acta 1302: 93-109
    • (1996) Biochim Biophys Acta , vol.1302 , pp. 93-109
    • Schoonjans, K.1    Staels, B.2    Auwerx, J.3
  • 2
    • 0032588487 scopus 로고    scopus 로고
    • PPAR gamma, the ultimate thrifty gene
    • 2. Auverx J (1999) PPAR gamma, the ultimate thrifty gene. Diabetologia 42: 1033-1049
    • (1999) Diabetologia , vol.42 , pp. 1033-1049
    • Auverx, J.1
  • 3
    • 0031934477 scopus 로고    scopus 로고
    • Monitoring of PPAR alpha protein expression in human tissue by the use of PPAR alpha-specific MAbs
    • 3. Su J, Simmons CJ, Wisely B, Ellis B, Winegar DA (1998) Monitoring of PPAR alpha protein expression in human tissue by the use of PPAR alpha-specific MAbs. Hybridoma 17: 47-53
    • (1998) Hybridoma , vol.17 , pp. 47-53
    • Su, J.1    Simmons, C.J.2    Wisely, B.3    Ellis, B.4    Winegar, D.A.5
  • 5
    • 0031748864 scopus 로고    scopus 로고
    • Regulation of apo A-1 gene expression by fibrates
    • 5. Staels B, Auverx J (1998) Regulation of apo A-1 gene expression by fibrates. Atherosclerosis 137: [Suppl] S19-S23
    • (1998) Atherosclerosis , vol.137 , Issue.SUPPL.
    • Staels, B.1    Auverx, J.2
  • 6
    • 0032530765 scopus 로고    scopus 로고
    • A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator-activated receptor α-deficient mice
    • 6. Djouadi F, Weinheimer CJ, Saffitz JE, Pitchford C, Bastin J, Gonzalez FJ (1998) A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator-activated Receptor α-deficient mice. J Clin Invest 102: 1083-1091
    • (1998) J Clin Invest , vol.102 , pp. 1083-1091
    • Djouadi, F.1    Weinheimer, C.J.2    Saffitz, J.E.3    Pitchford, C.4    Bastin, J.5    Gonzalez, F.J.6
  • 7
    • 0032403084 scopus 로고    scopus 로고
    • A mitochondrial ketogenic enzyme regulates its gene expression by association with the nuclear hormone receptor PPARα
    • 7. Meertens LM, Miyata KS, Cechetto JD, Rachubinski RA, Capone JP (1998) A mitochondrial ketogenic enzyme regulates its gene expression by association with the nuclear hormone receptor PPARα. EMBO J 17: 6972-6978
    • (1998) EMBO J , vol.17 , pp. 6972-6978
    • Meertens, L.M.1    Miyata, K.S.2    Cechetto, J.D.3    Rachubinski, R.A.4    Capone, J.P.5
  • 8
    • 0032479423 scopus 로고    scopus 로고
    • Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor α and γ activators in a tissue-and inducer-specific manner
    • 8. Motojima K, Passilly P, Peters JM, Gonzalez FJ, Latruffe N (1998) Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor α and γ activators in a tissue-and inducer-specific manner. J Biol Chem 273: 16710-16714
    • (1998) J Biol Chem , vol.273 , pp. 16710-16714
    • Motojima, K.1    Passilly, P.2    Peters, J.M.3    Gonzalez, F.J.4    Latruffe, N.5
  • 9
    • 0029784760 scopus 로고    scopus 로고
    • The peroxisome proliferator activated receptor α is a phosphoprotein:Regulation by insulin
    • 9. Shalev A, Siegrist-Kaiser CA, Yen PM et al. (1996) The peroxisome proliferator activated receptor α is a phosphoprotein: regulation by insulin. Endocrinology 137:4499-4502
    • (1996) Endocrinology , vol.137 , pp. 4499-4502
    • Shalev, A.1    Siegrist-Kaiser, C.A.2    Yen, P.M.3
  • 10
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
    • 10. Braissant O, Foufelle F, Scotto C, Dauça M, Wahli W (1996) Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 137: 354-366
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauça, M.4    Wahli, W.5
  • 11
    • 0029995670 scopus 로고    scopus 로고
    • Thiazolidinediones in the treatment of insulin resistance and type II diabetes
    • 11. Saltiel AR, Olefsky JM (1996) Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes 45: 1661-1669
    • (1996) Diabetes , vol.45 , pp. 1661-1669
    • Saltiel, A.R.1    Olefsky, J.M.2
  • 12
    • 0030590074 scopus 로고    scopus 로고
    • Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2
    • 12. Elbrecht A, Chen Y, Cullinan CA et al. (1996) Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2. Biochem Biophys Res Commun 224: 431-437
    • (1996) Biochem Biophys Res Commun , vol.224 , pp. 431-437
    • Elbrecht, A.1    Chen, Y.2    Cullinan, C.A.3
  • 13
    • 0028972025 scopus 로고
    • 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
    • 13. Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM (1995) 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83: 803-812
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 14
    • 0030985318 scopus 로고    scopus 로고
    • Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
    • 14. Krey G, Braissant O, L'Horset F et al. (1997) Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol Endocrinol 11: 779-791
    • (1997) Mol Endocrinol , vol.11 , pp. 779-791
    • Krey, G.1    Braissant, O.2    L'Horset, F.3
  • 15
    • 0030462770 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptors: Ligands and activators
    • 15. Forman BM, Chen J, Evans RM (1996) The peroxisome proliferator-activated receptors: ligands and activators. Ann NY Acad Sci 804: 266-275
    • (1996) Ann NY Acad Sci , vol.804 , pp. 266-275
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 16
    • 0030600556 scopus 로고    scopus 로고
    • The thiazolidinedione insulin sensitiser, BRL 49653, increases the expression of PPAR-gamma and aP2 in adipose tissue of high-fat-fed rats
    • 16. Pearson SL, Cawthorne MA, Clapham JC et al. (1996) The thiazolidinedione insulin sensitiser, BRL 49653, increases the expression of PPAR-gamma and aP2 in adipose tissue of high-fat-fed rats. Biochem Biophys Res Commun 229: 752-757
    • (1996) Biochem Biophys Res Commun , vol.229 , pp. 752-757
    • Pearson, S.L.1    Cawthorne, M.A.2    Clapham, J.C.3
  • 17
    • 0029745382 scopus 로고    scopus 로고
    • Thiazolidinediones produce a conformational change in peroxisome proliferator-activated receptor-gamma: Binding and activation correlate with antidiabetic actions in db/db mice
    • 17. Berger J, Bailey P, Biswas C et al. (1996) Thiazolidinediones produce a conformational change in peroxisome proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice. Endocrinology 137: 4189-4195
    • (1996) Endocrinology , vol.137 , pp. 4189-4195
    • Berger, J.1    Bailey, P.2    Biswas, C.3
  • 18
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • 18. Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 270: 12953-12956
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 19
    • 0032484224 scopus 로고    scopus 로고
    • A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor γ-activating properties
    • 19. Reginato MJ, Bailey ST, Krakow SL et al. (1998) A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor γ-activating properties. J Biol Chem 273: 32679-32684
    • (1998) J Biol Chem , vol.273 , pp. 32679-32684
    • Reginato, M.J.1    Bailey, S.T.2    Krakow, S.L.3
  • 20
    • 0030835678 scopus 로고    scopus 로고
    • The organization, promoter analysis, and expression of the human PPAR gamma gene
    • 20. Fajas L, Auboeuf D, Raspe E et al. (1997) The organization, promoter analysis, and expression of the human PPAR gamma gene. J Biol Chem 272: 18779-18789
    • (1997) J Biol Chem , vol.272 , pp. 18779-18789
    • Fajas, L.1    Auboeuf, D.2    Raspe, E.3
  • 21
    • 0030977450 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids
    • 21. Vidal-Puig AJ, Considine RV, Jimenez-Linan M et al. (1997) Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J Clin Invest 99: 2416-2422
    • (1997) J Clin Invest , vol.99 , pp. 2416-2422
    • Vidal-Puig, A.J.1    Considine, R.V.2    Jimenez-Linan, M.3
  • 22
    • 0004473133 scopus 로고    scopus 로고
    • PPAR-gamma gene expression is elevated in skeletal muscle of obese and type 2 diabetic subjects
    • 22. Park KS, Ciaraldi TP, Abrams-Carter L, Mudaliar S, Nikoulina SE, Henry RR (1997) PPAR-gamma gene expression is elevated in skeletal muscle of obese and type 2 diabetic subjects. Diabetes 46: 1230-1234
    • (1997) Diabetes , vol.46 , pp. 1230-1234
    • Park, K.S.1    Ciaraldi, T.P.2    Abrams-Carter, L.3    Mudaliar, S.4    Nikoulina, S.E.5    Henry, R.R.6
  • 23
    • 0030000088 scopus 로고    scopus 로고
    • Regulation of PPAR gamma gene expression by nutrition and obesity in rodents
    • 23. Vidal-Puig A, Jimenez-Linan M, Lowell BB et al. (1996) Regulation of PPAR gamma gene expression by nutrition and obesity in rodents. J Clin Invest 97: 2553-2561
    • (1996) J Clin Invest , vol.97 , pp. 2553-2561
    • Vidal-Puig, A.1    Jimenez-Linan, M.2    Lowell, B.B.3
  • 24
    • 0031964987 scopus 로고    scopus 로고
    • Depot-specific differences in adipose tissue gene expression in lean and obese subjects
    • 24. Lefebvre AM, Laville M, Vega N et al. (1998) Depot-specific differences in adipose tissue gene expression in lean and obese subjects. Diabetes 47: 98-103
    • (1998) Diabetes , vol.47 , pp. 98-103
    • Lefebvre, A.M.1    Laville, M.2    Vega, N.3
  • 25
    • 7844240131 scopus 로고    scopus 로고
    • Role of skeletal muscle in thiazolidinedione insulin sensitiser (PPAR gamma agonist) action
    • 25. Zierath JR, Ryder JW, Doebber T et al. (1998) Role of skeletal muscle in thiazolidinedione insulin sensitiser (PPAR gamma agonist) action. Endocrinology 193: 5034-5041
    • (1998) Endocrinology , vol.193 , pp. 5034-5041
    • Zierath, J.R.1    Ryder, J.W.2    Doebber, T.3
  • 26
    • 0026570417 scopus 로고
    • Regional similarities in the metabolic regulation of adipose tissue lipoprotein lipase
    • 26. Yost TJ, Eckel RH (1992) Regional similarities in the metabolic regulation of adipose tissue lipoprotein lipase. Metabolism 41: 33-36
    • (1992) Metabolism , vol.41 , pp. 33-36
    • Yost, T.J.1    Eckel, R.H.2
  • 27
    • 0025979358 scopus 로고
    • Multiple defects in muscle glycogen synthase activity contribute to reduced glycogen synthesis in non-insulin dependent diabetes mellitus
    • 27. Thorburn AW, Gumbiner B, Bulacan F, Brechtel G, Henry RR (1991) Multiple defects in muscle glycogen synthase activity contribute to reduced glycogen synthesis in non-insulin dependent diabetes mellitus. J Clin Invest 87: 489-495
    • (1991) J Clin Invest , vol.87 , pp. 489-495
    • Thorburn, A.W.1    Gumbiner, B.2    Bulacan, F.3    Brechtel, G.4    Henry, R.R.5
  • 28
    • 1842334456 scopus 로고    scopus 로고
    • 28. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (1997) Diabetes Care 20: 1183-1197
    • (1997) Diabetes Care , vol.20 , pp. 1183-1197
  • 29
    • 0029134591 scopus 로고
    • Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures
    • 29. Henry RR, Abrams L, Nikoulina S, Ciaraldi TP (1995) Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures. Diabetes 44: 936-946
    • (1995) Diabetes , vol.44 , pp. 936-946
    • Henry, R.R.1    Abrams, L.2    Nikoulina, S.3    Ciaraldi, T.P.4
  • 30
    • 0019551730 scopus 로고
    • "Western blotting": Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A
    • 30. Burnette WN (1981) "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A Anal Biochem 112: 195-203
    • (1981) Anal Biochem , vol.112 , pp. 195-203
    • Burnette, W.N.1
  • 31
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principal of protein-dye binding
    • 31. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principal of protein-dye binding. Anal Biochem 71: 248-254
    • (1976) Anal Biochem , vol.71 , pp. 248-254
    • Bradford, M.M.1
  • 32
    • 0030835678 scopus 로고    scopus 로고
    • The organization, promoter analysis, and expression of the human PPARγ gene
    • 32. Fajas L, Auboef D, Raspe E et al. (1997) The organization, promoter analysis, and expression of the human PPARγ gene. J Biol Chem 272: 18779-18789
    • (1997) J Biol Chem , vol.272 , pp. 18779-18789
    • Fajas, L.1    Auboef, D.2    Raspe, E.3
  • 33
    • 0024599795 scopus 로고
    • Immunochemical quantitation of fatty-acid-binding proteins. Tissue and intracellular distribution, postnatal development and influence of physiological conditions on rat heart and liver FABP
    • 33. Paulussen RJ, Geelen MJH, Beynen AC, Veerkamp JH (1989) Immunochemical quantitation of fatty-acid-binding proteins. Tissue and intracellular distribution, postnatal development and influence of physiological conditions on rat heart and liver FABP. Biochim Biophys Acta 1001: 201-209
    • (1989) Biochim Biophys Acta , vol.1001 , pp. 201-209
    • Paulussen, R.J.1    Geelen, M.J.H.2    Beynen, A.C.3    Veerkamp, J.H.4
  • 34
    • 0025370919 scopus 로고
    • Transcriptional regulation of actin and myosin genes during differentiation of a mouse muscle cell line
    • 34. Cox RD, Garner I, Buckingham ME (1990) Transcriptional regulation of actin and myosin genes during differentiation of a mouse muscle cell line. Differentiation 43: 183-191
    • (1990) Differentiation , vol.43 , pp. 183-191
    • Cox, R.D.1    Garner, I.2    Buckingham, M.E.3
  • 35
    • 0033514948 scopus 로고    scopus 로고
    • Reversing adipocyte differentiation: Implications for treatment of obesity
    • 35. Zhou YT, Wang ZW, Higa M, Newgard CB, Unger R (1999) Reversing adipocyte differentiation: implications for treatment of obesity. Proc Natl Acad Sci USA 96: 2391-2395
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2391-2395
    • Zhou, Y.T.1    Wang, Z.W.2    Higa, M.3    Newgard, C.B.4    Unger, R.5
  • 36
    • 0030679687 scopus 로고    scopus 로고
    • PPAR gamma and the molecular control of adipogenesis
    • 36. Brun RP, Spiegelman BM (1997) PPAR gamma and the molecular control of adipogenesis. J Endocrinol 155: 217-218
    • (1997) J Endocrinol , vol.155 , pp. 217-218
    • Brun, R.P.1    Spiegelman, B.M.2
  • 37
    • 0031898610 scopus 로고    scopus 로고
    • PPAR-γ: Adipogenic regulator and thiazolidinedione receptor
    • 37. Spiegelman BM (1998) PPAR-γ: adipogenic regulator and thiazolidinedione receptor. Diabetes 47: 507-514
    • (1998) Diabetes , vol.47 , pp. 507-514
    • Spiegelman, B.M.1
  • 38
    • 0032994523 scopus 로고    scopus 로고
    • Insulin acutely regulates the expression of the peroxisome proliferator-activated receptor-γ in human adipocytes
    • 38. Rieusset J, Andreelli F, Auboeuf D et al. (1999) Insulin acutely regulates the expression of the peroxisome proliferator-activated receptor-γ in human adipocytes. Diabetes 48: 699-705
    • (1999) Diabetes , vol.48 , pp. 699-705
    • Rieusset, J.1    Andreelli, F.2    Auboeuf, D.3
  • 39
    • 0032006547 scopus 로고    scopus 로고
    • Skeletal muscle peroxisome proliferator-activated receptor-γ expression in obesity and non-insulin-dependent diabetes mellitus
    • 39. Kruszynska YT, Mukherjee R, Jow L, Dana S, Paterniti JR, Olefsky JM (1998) Skeletal muscle peroxisome proliferator-activated receptor-γ expression in obesity and non-insulin-dependent diabetes mellitus. J Clin Invest 101: 543-548
    • (1998) J Clin Invest , vol.101 , pp. 543-548
    • Kruszynska, Y.T.1    Mukherjee, R.2    Jow, L.3    Dana, S.4    Paterniti, J.R.5    Olefsky, J.M.6
  • 40
    • 0023847920 scopus 로고
    • Transcriptional and posttranscriptional regulation of tyrosine aminotransferase by insulin in rat hepatoma cells
    • 40. Crettaz M, Muller-Wieland D, Kahn CR (1988) Transcriptional and posttranscriptional regulation of tyrosine aminotransferase by insulin in rat hepatoma cells. Biochemistry 27: 495-500
    • (1988) Biochemistry , vol.27 , pp. 495-500
    • Crettaz, M.1    Muller-Wieland, D.2    Kahn, C.R.3
  • 41
    • 0033525535 scopus 로고    scopus 로고
    • Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects
    • 41. Berger J, Leibowitz MD, Doebber TW et al. (1999) Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects. J Biol Chem 274: 6718-6725
    • (1999) J Biol Chem , vol.274 , pp. 6718-6725
    • Berger, J.1    Leibowitz, M.D.2    Doebber, T.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.