Production of a monoclonal antibody by ascites, hollow fiber system, and transgenic plants for vaccine production using CB.Hep-1 mAb as a study case

Biotechnology and Bioprocess Engineering

Volumn 17, Issue 1, 2012, Pages 145-159

  Valdés, Rodolfo ^a   Tamayo, Andrés ^a   González, Marcos ^a   Padilla, Sigifredo ^a   Geada, Déborah ^b   Ferro, William ^a   Milá, Lorely ^a   Gómez, Leonardo ^a   Alemán, Rosario ^a   Leyva, Alberto ^a   García, Cristina ^a   Mendoza, Otto ^a   Alvarez, Tatiana ^a   Dorta, Lamay ^a   Villega, Yanet ^a   Cecilia, Dobián ^a   Aragón, Hasel ^a   González, Tatiana ^a   Maylin La O ^a   López, Jorge ^a  

^a CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

^b Déborah Geada Institute of Tobacco Research   (Cuba)

Author keywords

Ascites; Hollow fiber bioreactor; Monoclonal antibody; Plantibody; Transgenic plants

Indexed keywords

ASCITES; HOLLOW FIBER; HOLLOW FIBER BIOREACTOR; IN-VITRO; MONOCLONAL ANTIBODIES (MAB); PLANTIBODY; PRODUCTION METHODS; STUDY CASE; TRANSGENIC ANIMALS; TRANSGENIC PLANTS; VACCINE PRODUCTION;

BIOTECHNOLOGY;

MONOCLONAL ANTIBODIES;

AFLATOXIN B1; AFLATOXIN B2; AFLATOXIN G1; AFLATOXIN G2; BOVINE SERUM ALBUMIN; EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CB.HEP 1; NICOTINE; PLANT DNA; PLANTIBODY; PLANTIBODY HB 01; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; ASCITES; BINDING AFFINITY; CASE STUDY; CONTROLLED STUDY; DNA CONTENT; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG PURIFICATION; ELECTROSPRAY MASS SPECTROMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL FILTRATION; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOLLOW FIBER; IN VITRO STUDY; ISOELECTRIC POINT; MASS SPECTROMETRY; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN SECRETION; RETROVIRUS; TANDEM MASS SPECTROMETRY; TOBACCO; TRANSGENIC PLANT; VACCINE PRODUCTION; VIRUS INACTIVATION;

ALGAE; ANIMALIA; BRYOPHYTA; DICOTYLEDONEAE; MUS; NICOTIANA TABACUM;

EID: 84861048197     PISSN: 12268372     EISSN: 19763816     Source Type: Journal    
DOI: 10.1007/s12257-011-0196-2     Document Type: Article

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