Plant pharming of a full-sized, tumour-targeting antibody using different expression strategies

Plant Biotechnology Journal

Volumn 7, Issue 1, 2009, Pages 59-72

  Villani, Maria Elena ^a   Morgun, Bogdan ^a   Brunetti, Patrizia ^a   Marusic, Carla ^a   Lombardi, Raffaele ^a   Pisoni, Ivan ^b   Bacci, Camilla ^b   Desiderio, Angiola ^a   Benvenuto, Eugenio ^a   Donini, Marcello ^a  

^a ENEA   (Italy)

^b Philogen SpA   (Italy)

Author keywords

Glycosylation; Immunotherapy; Molecular farming; Plantibody; Transient expression; Tumour targeting

Indexed keywords

CANCER ANTIBODY; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN; TENASCIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BIOSYNTHESIS; DRUG ANTAGONISM; EXPERIMENTAL NEOPLASM; GENE EXPRESSION; GENETIC TRANSFORMATION; GENETICS; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MOUSE; PROTEIN ENGINEERING; TOBACCO; TRANSGENIC PLANT;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEOPLASM; GENE EXPRESSION; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MOLECULAR SEQUENCE DATA; NEOPLASMS, EXPERIMENTAL; PLANTS, GENETICALLY MODIFIED; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; TENASCIN; TOBACCO; TRANSFORMATION, GENETIC;

AGROBACTERIUM; ARTICHOKE MOTTLED CRINKLE VIRUS; CYNARA SCOLYMUS; NICOTIANA BENTHAMIANA; NICOTIANA TABACUM; RHIZOBIUM;

EID: 57649121662     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/j.1467-7652.2008.00371.x     Document Type: Article

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