Large-scale production of recombinant hepatitis B surface antigen from Pichia pastoris

Journal of Biotechnology

Volumn 77, Issue 2-3, 2000, Pages 157-167

  Hardy, Eugenio ^a   Martínez, Eduardo ^a   Diago, David ^a   Díaz, Raúl ^a   González, Daniel ^a   Herrera, Luis ^a  

^a CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

Author keywords

Hepatitis B; Pichia pastoris; Production; Recombinant; Vaccine

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; RECOMBINANT HEPATITIS B VACCINE;

ACID PRECIPITATION; ADSORPTION; ANTIGEN PURIFICATION; ARTICLE; BIOREACTOR; CELL DESTRUCTION; DESORPTION; GEL PERMEATION CHROMATOGRAPHY; IMMUNOAFFINITY CHROMATOGRAPHY; ION EXCHANGE CHROMATOGRAPHY; PICHIA PASTORIS; PRACTICE GUIDELINE; PRIORITY JOURNAL; STANDARD; TECHNOLOGY; VACCINE PRODUCTION;

ADSORPTION; CHROMATOGRAPHY; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; HUMANS; HYDROGEN-ION CONCENTRATION; PICHIA; PRECIPITATION; VACCINES, SYNTHETIC;

EID: 0343314905     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1656(99)00201-1     Document Type: Article

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