Chromatographic removal combined with heat, acid and chaotropic inactivation of four model viruses

Journal of Biotechnology

Volumn 96, Issue 3, 2002, Pages 251-258

  Valdes R ^a   Ibarra, Neysi ^a   Ruibal, I ^b   Beldarrain A ^a   Noa, E ^b   Herrera, N ^b   Aleman R ^a   Padilla, S ^a   Garcia, J ^a   Perez M ^a   Morales, R ^c   Chong, E ^c   Reyes, B ^a   Quinones Y ^a   Agraz, A ^a   Herrera, L ^a  

^a CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

^b National Reference Center for AIDS   (Cuba)

^c National Center for Bioreagents   (Cuba)

Author keywords

Hybridoma; rHBsAg; Viral validation

Indexed keywords

AFFINITY CHROMATOGRAPHY; ANTIBODIES; DNA; PH EFFECTS; PROTEINS;

INACTIVATION CAPACITIES;

VIRUSES;

MONOCLONAL ANTIBODY; PROTEIN A;

ACIDITY; AFFINITY CHROMATOGRAPHY; ARTICLE; DNA VIRUS; ELUTION; HERPES SIMPLEX VIRUS 1; HIGH TEMPERATURE; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PARAINFLUENZA VIRUS 1; PARVOVIRUS; POLIOMYELITIS VIRUS 1; PRIORITY JOURNAL; VIRUS ENVELOPE; VIRUS INACTIVATION;

ANIMALS; ANTIBODIES, MONOCLONAL; CHROMATOGRAPHY, AFFINITY; DOGS; DRUG CONTAMINATION; FEASIBILITY STUDIES; HEAT; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; HIV; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; MICE, INBRED BALB C; PARVOVIRUS; POLIOVIRUS; SENDAI VIRUS; SENSITIVITY AND SPECIFICITY; STAPHYLOCOCCAL PROTEIN A; VACCINES, INACTIVATED; VACCINES, SYNTHETIC; VIRUSES;

CANINE PARVOVIRUS; HERPESVIRIDAE; PARVOVIRUS; POLIOVIRUS;

EID: 0037014561     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1656(02)00047-0     Document Type: Article

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