Staphylococcus aureus FabI: Inhibition, substrate recognition, and potential implications for in vivo essentiality

Structure

Volumn 20, Issue 5, 2012, Pages 802-813

  Schiebel, Johannes ^a   Chang, Andrew ^b,c   Lu, Hao ^b   Baxter, Michael V ^b   Tonge, Peter J ^b   Kisker, Caroline ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b STONY BROOK UNIVERSITY   (United States)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; ENZYME INHIBITOR; STAPHYLOCOCCUS AUREUS FABI; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; COMPARATIVE STUDY; DRUG TARGETING; ENZYME INHIBITION; ENZYME SUBSTRATE; FATTY ACID SYNTHESIS; IN VIVO STUDY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); FATTY ACIDS; KINETICS; LIGANDS; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 84861015861     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2012.03.013     Document Type: Article

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