Insertional inactivation of branched-chain α-keto acid dehydrogenase in Staphylococcus aureus leads to decreased branched-chain membrane fatty acid content and increased susceptibility to certain stresses

Applied and Environmental Microbiology

Volumn 74, Issue 19, 2008, Pages 5882-5890

  Singh, Vineet K ^a   Hattangady, Dipti S ^b   Giotis, Efstathios S ^b   Singh, Atul K ^b   Chamberlain, Neal R ^a   Stuart, Melissa K ^a   Wilkinson, Brian J ^b  

^a A T STILL UNIVERSITY   (United States)

^b ILLINOIS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; FATTY ACIDS; THEOREM PROVING; TOLUENE;

ACID CONTENTS; ALKALINE PHS; ANTIMICROBIAL SUBSTANCES; BACTERIAL SPECIES; CONSISTENT; EARLY STAGES; ENZYME COMPLEXES; EUKARYOTIC CELLS; FLUORESCENCE POLARIZATIONS; GROWTH MEDIUMS; INSERTIONAL INACTIVATIONS; KETO ACIDS; MEMBRANE FLUIDITIES; MULTIPLE STRESS CONDITIONS; S. AUREUS; STAPHYLOCOCCUS AUREUS; STRESS CONDITIONS;

ACIDS;

2 METHYLBUTYRIC ACID; 2 OXOISOVALERATE DEHYDROGENASE (LIPOAMIDE); FATTY ACID; HYDROGEN PEROXIDE; TOLUENE; 2-METHYLBUTYRATE; ALKALI; BACTERIAL PROTEIN; BUTYRIC ACID DERIVATIVE; OXIDIZING AGENT;

ADAPTATION; ANTIBIOTIC RESISTANCE; BACTERIUM; CATALYSIS; ENZYME ACTIVITY; FATTY ACID; GROWTH RATE; LOW TEMPERATURE; MUTATION; ORGANIC ACID; OXIDATION; PH; RODENT; SURVIVAL; TOLUENE;

ARTICLE; AUTOLYSIS; CONTROLLED STUDY; EUKARYOTIC CELL; FLUORESCENCE; GENETIC ANALYSIS; NONHUMAN; PH; STAPHYLOCOCCUS AUREUS; TEMPERATURE; ANIMAL; BACTERIAL COUNT; BACTERIUM ADHERENCE; CELL LINE; CELL MEMBRANE; CHEMISTRY; COLD; CULTURE MEDIUM; DRUG EFFECT; ENZYMOLOGY; EPITHELIUM CELL; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; INSTITUTE FOR CANCER RESEARCH MOUSE; LIVER; MEMBRANE FLUIDITY; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; MOUSE; OXIDATIVE STRESS; PHYSIOLOGY; SPLEEN; VIRULENCE;

BACTERIA (MICROORGANISMS); EUKARYOTA; STAPHYLOCOCCUS AUREUS;

3-METHYL-2-OXOBUTANOATE DEHYDROGENASE (LIPOAMIDE); ALKALIES; ANIMALS; BACTERIAL ADHESION; BACTERIAL PROTEINS; BUTYRATES; CELL LINE; CELL MEMBRANE; COLD; COLONY COUNT, MICROBIAL; CULTURE MEDIA; EPITHELIAL CELLS; FATTY ACIDS; FEMALE; GENE DELETION; HUMANS; LIVER; MEMBRANE FLUIDITY; MICE; MICE, INBRED ICR; MICROBIAL VIABILITY; MUTAGENESIS, INSERTIONAL; OXIDANTS; OXIDATIVE STRESS; SPLEEN; STAPHYLOCOCCUS AUREUS; TOLUENE; VIRULENCE;

EID: 54449095003     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.00882-08     Document Type: Article

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