In vivo genotoxicity of furan in F344 rats at cancer bioassay doses

Toxicology and Applied Pharmacology

Volumn 261, Issue 2, 2012, Pages 164-171

  Ding, Wei ^a   Petibone, Dayton M ^a   Latendresse, John R ^a   Pearce, Mason G ^a   Muskhelishvili, Levan ^a   White, Gene A ^a   Chang, Ching Wei ^a   Mittelstaedt, Roberta A ^a   Shaddock, Joseph G ^a   McDaniel, Lea P ^a   Doerge, Daniel R ^a   Morris, Suzanne M ^a   Bishop, Michelle E ^a   Manjanatha, Mugimane G ^a   Aidoo, Anane ^a   Heflich, Robert H ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Cell proliferation; DNA damage; In vivo Comet assay; Inflammation; Liver; Oxidative stress

Indexed keywords

DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; FURAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; FISCHER 344 RAT; GENE EXPRESSION; GENOTOXICITY; HISTOPATHOLOGY; IN VIVO STUDY; MALE; NEOPLASM; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALS; BONE MARROW; CARCINOGENICITY TESTS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FURANS; LIVER; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MUTAGENICITY TESTS; RATS; RATS, INBRED F344;

ANIMALIA; RATTUS; RODENTIA;

EID: 84860990389     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.03.021     Document Type: Article

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